Standard name
Human Ortholog
Description Subunit of Elongator complex; binds to microtubules via conserved alkaline residues; has two seven-bladed WD40 β propellers; Elongator complex is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0 0.05 0 0 0 0 0 0 0 0 0 0.05 0.09 0 0 0 0 0 0 0
Cytoplasm 0.99 0.97 0.97 0.94 0.93 0.92 0.87 0.83 0.77 0.74 0.73 0.79 0.99 0.99 1.0 0.91 0.94 0.94 0.98 0.94 0.94 0.84 0.81 0.82
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.12 0.11
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.08 0.14 0.1 0.36 0.38 0.37 0.26 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.08 0 0 0.1 0 0.05 0 0 0 0 0 0.09 0 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 1 0 2 5 4 3 1 2 2 0 0 0 0 0 1 0 0 0 0 0 0
Bud 0 0 1 3 2 2 12 12 5 10 13 6 3 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 7 14 6 14 23 15 10 7 11 14 18 0 4 4 21 23 11 0 0 0 0 0 0
Cytoplasm 84 169 267 241 362 435 607 468 206 243 252 333 306 378 480 372 253 247 95 167 281 166 243 308
Endoplasmic Reticulum 0 1 1 4 1 6 0 2 0 1 2 3 3 2 1 10 8 3 0 0 5 15 34 40
Endosome 0 0 0 1 1 1 3 3 0 2 2 2 0 0 0 0 0 1 0 1 1 0 0 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 0 0 0 1 1 1
Mitochondria 1 1 1 4 12 36 101 58 98 126 127 111 0 0 1 2 1 0 0 0 2 2 3 4
Nucleus 0 1 0 0 0 3 1 6 0 3 2 1 1 1 0 1 3 1 0 0 1 0 0 0
Nuclear Periphery 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 1 8 8 30 14 21 59 11 15 12 18 1 2 0 37 6 12 0 3 5 7 10 14
Unique Cell Count 85 175 275 256 391 473 697 566 269 328 347 421 310 382 482 410 270 262 97 178 299 197 299 375
Labelled Cell Count 86 181 292 268 424 522 767 625 331 413 427 495 314 387 486 445 295 278 97 178 299 197 299 375


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 13.2 11.7 11.1 10.3 9.8 7.4 7.0 7.2 5.7 5.5 5.4 5.9 12.9 12.3 11.9 18.4 18.2 17.6 11.4 11.8 12.5
Std Deviation (1e-4) 2.1 2.0 1.4 1.3 1.2 1.1 1.0 1.2 1.3 1.1 1.1 1.1 1.8 1.5 1.4 3.4 3.5 3.2 1.7 1.7 1.9
Intensity Change (Log2) – – – -0.12 -0.18 -0.59 -0.66 -0.64 -0.96 -1.02 -1.04 -0.91 0.22 0.15 0.1 0.72 0.71 0.66 0.04 0.09 0.17


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 2.5 2.8 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.7 -1.0 -0.1 -2.4 -2.7 -1.5 -1.1 -0.6 -0.5 -4.0 -3.1 -3.7 0 1.6 -0.5
Cytoplasm -1.7 -2.5 -2.8 -4.7 -5.9 -7.1 -7.8 -8.2 -6.7 1.4 1.8 2.9 -3.3 -1.9 -1.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 2.5 4.4 6.5 5.3 10.9 11.4 11.1 9.1 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0.1 2.6 0 0.1 3.8 0.7 1.1 0.4 0.9 0 0 0 3.2 -0.5 1.0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.3959 6.1362 5.3407 5.1354 5.4018 6.2193 4.4387 6.2783 5.2764 4.9472 5.2123 5.3727 4.9044 7.4423 6.6937 6.5153 4.9898 6.8328
Actin 0.0144 0.0022 0.0057 0.088 0.0517 0.0023 0.0236 0.0003 0.0164 0.0106 0.0033 0.0162 0.0216 0.0001 0.0088 0.0124 0.007 0.0061
Bud 0.0005 0.0008 0.0011 0.0011 0.0004 0.0007 0.0009 0.0008 0.0019 0.0012 0.0042 0.0005 0.0017 0.0018 0.0005 0.0013 0.0006 0.0047
Bud Neck 0.0033 0.0004 0.0011 0.0024 0.0007 0.0017 0.0028 0.0002 0.0014 0.0006 0.0006 0.0008 0.0016 0.0001 0.0003 0.0007 0.0008 0.0011
Bud Periphery 0.0005 0.0003 0.0009 0.0012 0.0001 0.001 0.0011 0.0003 0.0021 0.0007 0.0074 0.0005 0.0014 0.0004 0.0002 0.0009 0.0005 0.0037
Bud Site 0.0064 0.0101 0.0038 0.0027 0.0006 0.0004 0.0044 0.0028 0.0066 0.001 0.0082 0.0003 0.0017 0.005 0.001 0.0046 0.0008 0.0004
Cell Periphery 0.001 0.0009 0.0011 0.0011 0.0001 0.0006 0.0006 0.0001 0.0004 0.0001 0.0002 0.0001 0.0004 0.0001 0.0001 0.0002 0.0001 0.0002
Cytoplasm 0.7018 0.8583 0.7891 0.7662 0.619 0.8786 0.8131 0.9563 0.817 0.7629 0.7834 0.8627 0.8094 0.9599 0.9001 0.8666 0.7364 0.9038
Cytoplasmic Foci 0.0327 0.0194 0.0282 0.0128 0.058 0.0156 0.0191 0.0092 0.0243 0.0246 0.0208 0.0191 0.0214 0.0074 0.0195 0.0175 0.0461 0.0135
Eisosomes 0.0004 0 0.0003 0.0099 0.0001 0 0.0002 0 0.0004 0.0001 0 0 0.0002 0 0.0001 0 0.0001 0.0002
Endoplasmic Reticulum 0.0267 0.0088 0.0125 0.0212 0.0065 0.0106 0.0245 0.0037 0.0103 0.0058 0.0064 0.0108 0.0258 0.0018 0.006 0.0113 0.0087 0.0152
Endosome 0.0557 0.0427 0.0389 0.0369 0.2094 0.0331 0.0504 0.0165 0.0646 0.1035 0.0928 0.0586 0.0488 0.0173 0.0314 0.0459 0.1224 0.0342
Golgi 0.0094 0.0043 0.0066 0.0089 0.0135 0.0058 0.0071 0.0012 0.0148 0.0203 0.0235 0.0132 0.0087 0.0007 0.0055 0.0061 0.0207 0.0041
Lipid Particles 0.0095 0.0005 0.0089 0.0029 0.004 0.0001 0.0055 0 0.0038 0.0053 0.0013 0.0009 0.006 0 0.0014 0.0037 0.0227 0.0003
Mitochondria 0.0171 0.0014 0.014 0.0036 0.0021 0.0023 0.0043 0.0003 0.0119 0.0083 0.0159 0.0072 0.011 0.0004 0.0064 0.0032 0.0064 0.0043
None 0.0966 0.0366 0.0605 0.0067 0.0037 0.0374 0.007 0.0023 0.0052 0.0012 0.0009 0.0009 0.0062 0.0011 0.0077 0.0029 0.0025 0.0011
Nuclear Periphery 0.0034 0.0009 0.0025 0.007 0.0017 0.001 0.0139 0.0005 0.0024 0.0091 0.0017 0.0017 0.0079 0.0003 0.0021 0.0026 0.0049 0.0019
Nucleolus 0.0005 0.0001 0.0002 0.0004 0 0.0001 0.0004 0 0.0003 0.0003 0.0005 0 0.0003 0 0.0001 0.0003 0.0003 0.0001
Nucleus 0.0019 0.0011 0.0017 0.0019 0.0009 0.0009 0.005 0.0007 0.0014 0.0018 0.002 0.0007 0.0015 0.0005 0.001 0.0029 0.0032 0.0008
Peroxisomes 0.0058 0.0002 0.0096 0.0009 0.0132 0.0002 0.0026 0.0001 0.0013 0.0017 0.001 0.0005 0.0075 0 0.002 0.0037 0.0031 0.0001
Punctate Nuclear 0.002 0.0002 0.0011 0.0009 0.0041 0.0001 0.0024 0.0001 0.0012 0.0027 0.0003 0.0004 0.0075 0.0001 0.0004 0.0015 0.0021 0.0002
Vacuole 0.0092 0.009 0.0106 0.0198 0.007 0.006 0.0087 0.0037 0.0097 0.0294 0.0201 0.0031 0.0078 0.0023 0.0042 0.0091 0.0073 0.0026
Vacuole Periphery 0.0015 0.0017 0.0015 0.0037 0.0034 0.0017 0.0023 0.0007 0.0027 0.0088 0.0053 0.0016 0.0016 0.0007 0.0012 0.0025 0.0037 0.0013

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 52.6763 55.4238 51.9497 49.2096 51.6761 37.7382 40.4491 37.8225 38.6696 47.4851
Translational Efficiency 1.1106 1.0454 1.018 1.0798 0.8797 1.0387 1.0413 0.7398 0.7145 0.7237

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1643 931 2825 1143 1271 1016 1458 2014 2914 1947 4283 3157

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1069.60 1313.28 1391.02 1374.31 1176.86 1267.92 1343.99 1408.93 1116.38 1289.61 1375.01 1396.40
Standard Deviation 180.31 217.16 173.79 190.08 174.01 197.49 190.28 192.53 185.39 208.36 180.95 192.37
Intensity Change Log 2 — 0.296103 0.379072 0.361636 — 0.107521 0.191580 0.259657 — 0.200389 0.283893 0.309112

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000162 0.000533 0.000155 0.000790 0.000208 0.000892 0.000180 0.000462 0.000182 0.000720 0.000164 0.000581
Bud Neck 0.000477 0.000342 0.000806 0.002000 0.000302 0.000584 0.001357 0.001018 0.000401 0.000469 0.000994 0.001374
Bud Site 0.018529 0.020209 0.010306 0.029010 0.016906 0.032884 0.010123 0.014530 0.017821 0.026824 0.010244 0.019773
Cell Periphery 0.000169 0.000254 0.000260 0.000831 0.000203 0.000251 0.000145 0.000518 0.000184 0.000252 0.000221 0.000632
Cytoplasm 0.839829* 0.837300* 0.737436* 0.761637* 0.826600* 0.757310* 0.658757* 0.820886* 0.834059* 0.795559* 0.710652* 0.799434*
Cytoplasmic Foci 0.084459 0.094604 0.022161 0.035532 0.108215 0.142388 0.052973 0.025755 0.094821 0.119539 0.032650 0.029295
Eisosomes 0.000004 0.000004 0.000002 0.000010 0.000003 0.000010 0.000006 0.000003 0.000004 0.000007 0.000004 0.000005
Endoplasmic Reticulum 0.002985 0.004570 0.000910 0.000607 0.004104 0.003539 0.002629 0.000651 0.003473 0.004032 0.001495 0.000635
Endosome 0.004576 0.004888 0.005040 0.009249 0.004417 0.009563 0.010169 0.004760 0.004507 0.007327 0.006786 0.006385
Golgi 0.009332 0.011863 0.003424 0.008103 0.013067 0.016736 0.001961 0.006214 0.010961 0.014406 0.002926 0.006898
Lipid Particles 0.000550 0.001016 0.001981 0.004275 0.000545 0.000913 0.002183 0.001806 0.000548 0.000963 0.002050 0.002700
Mitochondria 0.000500 0.000561 0.000406 0.000762 0.000211 0.000993 0.000053 0.000253 0.000374 0.000786 0.000286 0.000437
Mitotic Spindle 0.001119 0.002489 0.000328 0.009061 0.000698 0.002816 0.000990 0.002087 0.000935 0.002659 0.000553 0.004612
None 0.001046 0.001032 0.000137 0.000124 0.000263 0.000141 0.000607 0.000084 0.000704 0.000567 0.000297 0.000099
Nuclear Periphery 0.000038 0.000019 0.000030 0.000111 0.000015 0.000047 0.000154 0.000046 0.000028 0.000034 0.000072 0.000070
Nuclear Periphery Foci 0.000483 0.000835 0.000470 0.001498 0.000461 0.000390 0.001770 0.000624 0.000473 0.000603 0.000912 0.000941
Nucleolus 0.000249 0.000043 0.000169 0.000149 0.000020 0.000056 0.000151 0.000143 0.000149 0.000050 0.000163 0.000145
Nucleus 0.003933 0.002129 0.003921 0.003770 0.001636 0.001483 0.013665 0.004457 0.002931 0.001792 0.007238 0.004209
Peroxisomes 0.000297 0.000255 0.000370 0.000935 0.000187 0.000744 0.000364 0.000503 0.000249 0.000511 0.000368 0.000660
Vacuole 0.017265 0.011107 0.199749 0.124627 0.011319 0.020899 0.236365* 0.108330 0.014672 0.016217 0.212214* 0.114230
Vacuole Periphery 0.013998 0.005947 0.011938 0.006919 0.010621 0.007360 0.005400 0.006870 0.012525 0.006685 0.009712 0.006888

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.32 -0.15 -5.68 -1.29 -5.33 -2.08 1.13 -1.18 1.19 -1.30 -2.86 0.25 -2.90 0.70 -2.91
Bud Neck 2.63 -6.68 -12.03 -13.35 -9.20 -6.51 -12.59 -9.44 -5.83 2.82 -2.07 -13.78 -14.27 -13.55 -5.11
Bud Site -0.99 6.91 -4.16 -3.31 -8.19 -7.91 6.31 2.08 9.15 -3.77 -6.67 9.26 -1.36 4.88 -8.70
Cell Periphery -4.03 -4.23 -8.48 -7.11 -7.12 -2.24 3.57 -2.53 -2.08 -3.07 -4.59 -2.29 -5.39 -4.43 -4.91
Cytoplasm 0.37 14.67 9.41 8.20 -1.78 6.91 17.35 1.83 -5.82 -16.84 5.80 21.83 7.57 0.74 -13.59
Cytoplasmic Foci -1.88 18.29 12.96 12.49 -6.90 -5.13 12.21 19.44 21.56 11.79 -5.72 22.70 23.71 24.84 2.45
Eisosomes -0.11 3.63 -3.42 -3.38 -4.57 -5.74 -6.00 0.50 5.85 6.16 -5.08 0.56 -2.68 2.04 -3.07
Endoplasmic Reticulum -1.18 3.83 4.55 3.24 1.75 0.51 2.16 5.05 3.24 4.94 -0.64 4.58 6.75 4.54 4.60
Endosome -0.51 -1.27 -4.03 -3.47 -3.63 -5.29 -8.42 -0.47 5.03 7.96 -4.80 -6.51 -3.37 1.77 1.20
Golgi -2.83 9.14 1.47 3.14 -2.92 -2.46 13.92 6.29 7.14 -4.33 -3.92 15.64 5.40 7.81 -4.54
Lipid Particles -3.74 -11.26 -8.79 -7.57 -5.23 -3.27 -11.78 -10.86 -5.92 2.33 -4.86 -15.95 -12.45 -9.49 -3.28
Mitochondria -0.19 0.66 -0.51 -0.24 -0.80 -2.12 6.30 -0.47 2.04 -3.69 -1.64 0.93 -0.15 1.43 -0.78
Mitotic Spindle -1.30 1.30 -3.52 -2.71 -3.98 -2.22 -1.24 -2.86 0.69 -1.71 -2.37 0.88 -4.06 -1.71 -4.67
None 0.02 5.68 6.16 1.29 0.52 4.20 -1.12 7.12 2.91 1.75 0.39 3.08 7.11 1.38 1.95
Nuclear Periphery 1.06 0.26 -2.29 -3.44 -2.88 -1.45 -5.35 -2.60 -0.07 3.66 -0.38 -3.43 -2.69 -2.16 0.27
Nuclear Periphery Foci -2.30 -0.44 -6.93 -3.65 -7.05 0.95 -9.05 -3.55 -3.94 7.55 -1.56 -7.45 -7.48 -4.20 -0.59
Nucleolus 1.37 0.53 0.65 -4.89 1.15 -1.66 -13.35 -16.96 -4.03 0.31 1.17 -0.16 0.02 -6.37 1.77
Nucleus 2.25 -1.02 -0.83 -3.52 0.28 0.94 -11.86 -7.57 -7.80 7.53 2.71 -9.19 -4.79 -7.63 4.97
Peroxisomes 1.44 -2.44 -7.24 -7.67 -6.37 -8.02 -6.43 -7.94 3.09 -3.15 -6.65 -5.65 -9.91 -2.69 -6.81
Vacuole 3.12 -39.89 -20.19 -20.97 8.90 -4.70 -31.47 -27.09 -23.08 15.04 -1.31 -50.98 -33.26 -31.73 18.11
Vacuole Periphery 4.58 1.84 5.03 -0.19 5.00 2.36 5.11 3.60 0.84 -1.94 5.15 3.51 6.35 0.36 4.61
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of Elongator complex; binds to microtubules via conserved alkaline residues; has two seven-bladed WD40 β propellers; Elongator complex is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Elp2

Elp2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Elp2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available