Standard name
Human Ortholog
Description 6-phosphogluconolactonase; protein abundance increases in response to DNA replication stress; SOL4 has a paralog, SOL3, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0.06 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0.05 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0 0 0 0 0 0 – 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.99 1.0 1.0 0.92 0.84 0.83 0.65 0.7 0.64 – 0.76 0.98 0.99 0.99 0.98 0.95 0.95 0.9 0.93 0.77 0.91 0.9 0.88
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.05 0.07 0.11 0.06 0.3 0.44 – 0.17 0 0 0 0 0 0 0 0 0.08 0 0 0
Nucleus 0 0 0 0 0 0 0 0.12 0.05 0.08 – 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0.06 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0.09 0.06 0.12 0.08 0.08 – 0.1 0 0 0 0 0.11 0.12 0 0 0.07 0 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 1 0 1 0 0
Bud 0 2 0 0 0 0 1 1 1 1 – 0 0 0 0 0 0 0 2 9 0 1 0 2
Bud Neck 1 0 0 0 0 2 0 0 0 0 – 0 0 0 0 0 0 0 2 0 0 1 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 1 0 0 0 0 0 0 0 – 2 0 0 1 3 4 2 0 0 0 0 0 0
Cytoplasm 394 588 20 18 34 36 39 11 51 16 – 32 83 279 269 297 243 231 369 546 30 171 93 139
Endoplasmic Reticulum 0 1 0 0 1 0 0 0 1 0 – 0 0 0 0 8 13 9 0 0 0 1 0 0
Endosome 1 1 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 2 5 0 0 0 0
Golgi 1 0 0 0 0 0 0 0 0 0 – 0 0 0 0 1 1 0 4 4 0 0 0 0
Mitochondria 3 2 0 0 2 3 5 1 22 11 – 7 0 0 2 5 0 4 11 5 3 0 1 2
Nucleus 0 0 0 0 0 0 2 2 4 2 – 2 0 5 2 0 3 2 0 1 0 1 0 0
Nuclear Periphery 0 1 0 0 0 0 0 1 0 1 – 0 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 1 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 2 3 0 0 0 0
Vac/Vac Membrane 3 0 0 0 1 4 3 2 6 2 – 4 1 1 1 10 28 30 4 2 2 3 5 6
Unique Cell Count 402 592 20 18 37 43 47 17 73 25 42 85 283 271 304 255 243 409 586 40 188 104 159
Labelled Cell Count 403 596 21 18 39 45 50 18 85 33 47 85 285 275 324 293 278 409 586 40 188 104 159


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.4 5.1 4.5 4.4 5.3 5.9 6.2 6.3 5.7 5.7 – 6.9 6.1 7.3 8.1 9.8 12.1 11.6 9.7 5.9 10.4
Std Deviation (1e-4) 1.6 1.6 0.5 0.4 1.8 1.7 2.4 2.5 2.7 3.2 – 4.2 1.7 2.8 3.5 3.2 4.1 4.4 17.3 1.7 19.1
Intensity Change (Log2) – – – -0.05 0.23 0.38 0.47 0.48 0.35 0.34 – 0.61 0.44 0.7 0.85 1.13 1.43 1.36 1.11 0.39 1.21

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP70001020WT3HU80HU120HU16001020WT3rpd3Δ_1rpd3Δ_2rpd3Δ_301020WT1AF100AF140AF18001020
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Neck – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Bud Site – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Cell Periphery – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Endosome – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Golgi – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Mitochondria – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nuclear Periphery – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Peroxisomes – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
SpindlePole – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Cytoplasm – -1.3 -1.9 -2.0 -2.9 -2.8 -3.0 – -2.4 -0.7 -0.5 -0.4 -0.7 -1.0 -1.0
Nucleus – 0 0 0 0 0 0 – 0 0 0 0 0 0 0
Vacuole – 0 0 0 0 0 0 – 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.275 3.1738 2.8474 3.3465 2.8533 3.2627 12.053 12.5208 12.6372 11.5783 11.6937 12.9677 7.0506 7.6174 6.836 6.8307 6.6893 7.3705
Actin 0.0292 0.0059 0.0064 0.0005 0.0003 0.0004 0.0144 0.0009 0.0039 0.001 0.0064 0.0076 0.0298 0.0084 0.0138 0.0106 0.0218 0.0039
Bud 0.0002 0.0011 0.0003 0.0002 0.0001 0.0002 0.0058 0.0007 0.0009 0.0002 0.0032 0.0014 0.0007 0.0049 0.0015 0.0016 0.0002 0.0006
Bud Neck 0.0011 0.0003 0.0008 0.0004 0.0004 0.0011 0.0052 0.0003 0.0005 0.0007 0.0007 0.0015 0.0007 0.0004 0.0013 0.0035 0.0006 0.0055
Bud Periphery 0.0002 0.0002 0.0002 0.0001 0 0.0001 0.0062 0.0001 0.0004 0.0001 0.0017 0.0011 0.0007 0.0015 0.0011 0.0011 0.0003 0.0003
Bud Site 0.0006 0.0019 0.0009 0.0001 0.0001 0.0001 0.004 0.0033 0.0007 0.0002 0.0003 0.0002 0.0011 0.0107 0.0039 0.0013 0.0004 0.0016
Cell Periphery 0.0001 0.0001 0.0001 0 0 0 0.0003 0.0001 0.0001 0 0 0 0.0001 0.0002 0.0003 0.0001 0.0002 0.0001
Cytoplasm 0.8233 0.8684 0.8669 0.9254 0.9359 0.9125 0.8374 0.9523 0.9182 0.926 0.9335 0.9132 0.746 0.866 0.8655 0.7935 0.7244 0.8602
Cytoplasmic Foci 0.0076 0.0042 0.0076 0.0072 0.0092 0.0087 0.0127 0.0024 0.006 0.0044 0.0068 0.0064 0.0273 0.0056 0.0035 0.0186 0.0056 0.0117
Eisosomes 0.0002 0.0001 0.0001 0 0 0 0.0001 0 0 0 0 0 0.0001 0 0.0001 0 0.0003 0.0001
Endoplasmic Reticulum 0.0047 0.0028 0.0058 0.0017 0.0014 0.0027 0.0046 0.0014 0.0017 0.0018 0.0044 0.0023 0.0045 0.002 0.004 0.0059 0.0086 0.0027
Endosome 0.0087 0.0015 0.0073 0.0011 0.0016 0.0042 0.0129 0.0007 0.0011 0.001 0.0066 0.0034 0.0155 0.0055 0.0043 0.021 0.0149 0.0035
Golgi 0.0021 0.0002 0.0007 0.0001 0.0001 0.0001 0.003 0.0001 0.0005 0.0001 0.0006 0.0009 0.0046 0.0018 0.002 0.0031 0.0044 0.0012
Lipid Particles 0.0014 0.0001 0.0004 0.0002 0 0.0001 0.0023 0 0.0002 0.0001 0.0001 0.0018 0.0059 0.0006 0.001 0.0008 0.0096 0.0016
Mitochondria 0.0006 0.0002 0.0003 0.0001 0.0001 0.0002 0.0025 0.0001 0.0003 0.0002 0.0007 0.0003 0.0021 0.0012 0.0057 0.0014 0.0065 0.0006
None 0.0893 0.1017 0.087 0.0545 0.0426 0.0498 0.0256 0.0189 0.0434 0.0317 0.0048 0.019 0.1111 0.0763 0.0757 0.08 0.0668 0.0914
Nuclear Periphery 0.007 0.0011 0.0031 0.0012 0.0013 0.002 0.0099 0.0015 0.0017 0.0014 0.0044 0.0029 0.0131 0.0027 0.0029 0.0151 0.0432 0.0027
Nucleolus 0.0002 0.0001 0.0001 0 0 0.0001 0.0003 0 0.0001 0 0 0.0001 0.0004 0.0001 0.0006 0.0004 0.0005 0.0001
Nucleus 0.0186 0.0075 0.0082 0.0059 0.0045 0.0141 0.0413 0.0155 0.0161 0.0289 0.0222 0.0336 0.0175 0.0082 0.0087 0.0129 0.0134 0.0077
Peroxisomes 0.0006 0.0004 0.0003 0.0001 0.0003 0.0001 0.0024 0.0001 0.0018 0.0002 0.0005 0.0009 0.0096 0.0008 0.0005 0.0034 0.072 0.0005
Punctate Nuclear 0.0027 0.0009 0.0012 0.0007 0.0015 0.0021 0.0061 0.0009 0.0017 0.0015 0.0018 0.0024 0.0074 0.0015 0.0016 0.0231 0.0024 0.0035
Vacuole 0.0011 0.0011 0.0019 0.0005 0.0005 0.0011 0.0022 0.0005 0.0006 0.0003 0.001 0.0007 0.001 0.0014 0.0015 0.0018 0.0014 0.0006
Vacuole Periphery 0.0004 0.0001 0.0003 0.0001 0.0001 0.0002 0.0008 0.0001 0.0001 0.0001 0.0002 0.0002 0.0008 0.0003 0.0003 0.0006 0.0024 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression – – – – – – – – – –
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression –
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
693 122 2275 617 1188 2088 2116 1363 1881 2210 4391 1980

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 618.16 870.33 1311.74 809.00 662.81 840.62 831.68 879.00 646.36 842.26 1080.40 857.19
Standard Deviation 71.69 98.46 704.20 295.23 89.70 117.26 230.18 285.48 86.25 116.50 583.10 290.37
Intensity Change Log 2 — 0.493582 1.085430 0.388159 — 0.342858 0.327433 0.407268 — 0.417561 0.742678 0.398078

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000167 0.000317 0.000166 0.000880 0.000071 0.000249 0.000266 0.000398 0.000106 0.000253 0.000214 0.000548
Bud Neck 0.022828 0.021184 0.005695 0.009508 0.004195 0.027857 0.005481 0.006773 0.011060 0.027489 0.005592 0.007625
Bud Site 0.008306 0.012862 0.009074 0.019118 0.002029 0.018706 0.015932 0.044816 0.004341 0.018383 0.012379 0.036808
Cell Periphery 0.000330 0.000193 0.000264 0.000240 0.000132 0.000243 0.000150 0.000457 0.000205 0.000240 0.000209 0.000390
Cytoplasm 0.423777 0.464788 0.691364 0.468129 0.584310 0.536291 0.521813 0.574666 0.525166 0.532344 0.609658 0.541467
Cytoplasmic Foci 0.329330 0.251382 0.007217 0.050740 0.166494 0.133573 0.012425 0.019076 0.226486 0.140077 0.009726 0.028943
Eisosomes 0.000321 0.000118 0.000012 0.000073 0.000086 0.000154 0.000028 0.000036 0.000173 0.000152 0.000020 0.000048
Endoplasmic Reticulum 0.000745 0.001655 0.000432 0.001831 0.000673 0.000565 0.001503 0.001029 0.000700 0.000626 0.000948 0.001279
Endosome 0.009272 0.017695 0.000930 0.023104 0.006156 0.009705 0.001918 0.003475 0.007304 0.010146 0.001406 0.009592
Golgi 0.005856 0.002592 0.000222 0.003027 0.000722 0.002588 0.000629 0.003015 0.002613 0.002588 0.000418 0.003019
Lipid Particles 0.012740 0.004958 0.000349 0.003644 0.005516 0.003680 0.000883 0.001010 0.008177 0.003751 0.000607 0.001831
Mitochondria 0.013722 0.001816 0.000475 0.005931 0.000929 0.006260 0.000999 0.000691 0.005642 0.006015 0.000727 0.002324
Mitotic Spindle 0.000227 0.006200 0.018285 0.046466 0.000901 0.006495 0.021827 0.026978 0.000653 0.006479 0.019991 0.033051
None 0.004622 0.001323 0.024207 0.011049 0.006452 0.003696 0.007341 0.016979 0.005778 0.003565 0.016079 0.015131
Nuclear Periphery 0.000264 0.000388 0.000562 0.001158 0.000396 0.000386 0.001591 0.000998 0.000347 0.000386 0.001058 0.001048
Nuclear Periphery Foci 0.000380 0.001316 0.000545 0.001838 0.000604 0.000261 0.000611 0.001802 0.000521 0.000319 0.000577 0.001813
Nucleolus 0.003272 0.000881 0.000727 0.001114 0.000759 0.001330 0.001138 0.000973 0.001685 0.001305 0.000925 0.001017
Nucleus 0.128134 0.117040 0.214347 0.199686 0.182660 0.182072 0.350552 0.213237 0.162571 0.178482 0.279984 0.209014
Peroxisomes 0.010302 0.008864 0.000106 0.002074 0.001746 0.005170 0.000369 0.000441 0.004898 0.005374 0.000233 0.000950
Vacuole 0.024194 0.083383 0.024792 0.145459 0.034633 0.059251 0.053919 0.080237 0.030787 0.060583 0.038828 0.100561
Vacuole Periphery 0.001212 0.001046 0.000230 0.004931 0.000535 0.001468 0.000625 0.002912 0.000785 0.001445 0.000420 0.003541

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.36 -2.03 -2.59 -1.44 -2.25 -5.65 -6.82 -7.98 -2.89 -2.25 -4.81 -7.71 -6.27 -3.13 -3.50
Bud Neck 0.37 6.75 6.24 2.15 -0.55 -13.35 -3.36 -1.65 11.51 0.47 -8.61 4.78 4.33 11.94 0.30
Bud Site -1.17 -0.39 -2.18 -0.31 -2.37 -10.03 -6.81 -8.87 -2.92 -5.24 -8.47 -6.46 -8.82 -2.10 -6.13
Cell Periphery 2.88 2.13 4.63 0.57 3.74 -4.66 -0.57 -4.36 -1.16 -4.10 -1.75 -0.08 -1.94 -0.35 -1.94
Cytoplasm -1.03 -16.85 1.04 1.56 15.55 5.10 14.88 7.48 3.29 -6.30 -0.81 -0.73 5.63 6.57 7.11
Cytoplasmic Foci 3.86 36.03 31.50 10.73 -9.40 5.26 29.79 28.03 30.91 -4.77 14.10 43.50 39.80 30.91 -10.23
Eisosomes 8.32 16.17 13.15 3.23 -15.58 -3.49 14.45 11.89 5.95 -3.65 1.15 19.17 15.56 5.75 -15.36
Endoplasmic Reticulum -1.40 2.28 -5.87 -0.27 -7.46 1.09 -12.40 -6.36 -7.54 6.79 0.81 -8.93 -8.64 -8.35 -1.14
Endosome -2.58 9.59 -1.00 1.55 -4.91 -4.15 8.64 6.84 9.89 -1.76 -3.46 13.29 2.51 5.00 -5.45
Golgi 2.88 7.69 5.18 1.00 -2.54 -4.11 1.72 -1.57 1.69 -2.27 0.09 7.76 2.52 2.04 -3.21
Lipid Particles 4.35 10.48 8.14 1.48 -4.54 2.48 6.26 6.21 8.92 -0.21 6.55 11.77 10.30 6.93 -4.91
Mitochondria 4.86 5.49 4.04 -0.86 -1.95 -5.67 -0.31 1.85 6.09 3.56 -0.28 5.42 4.43 4.93 -1.49
Mitotic Spindle -1.17 -11.95 -6.03 -3.73 -1.81 -4.24 -9.31 -8.34 -5.97 -0.52 -4.82 -14.49 -10.31 -7.35 -1.60
None 2.25 -7.95 -1.11 -3.21 5.37 2.46 -0.61 -2.89 -5.30 -3.00 2.34 -7.35 -3.10 -5.51 2.36
Nuclear Periphery -1.20 -15.49 -11.62 -6.93 -5.90 -0.05 -23.13 -11.97 -11.04 10.71 -0.87 -24.97 -16.62 -13.01 3.18
Nuclear Periphery Foci -2.36 -2.82 -4.79 -1.18 -3.69 3.89 -2.61 -4.48 -6.05 -3.45 2.29 -3.88 -6.38 -7.58 -4.84
Nucleolus 1.43 1.55 1.52 0.55 -0.36 -3.36 -0.25 0.24 2.50 0.36 0.54 1.48 1.53 2.90 0.18
Nucleus 0.29 -18.45 -7.23 -4.73 5.75 0.16 -26.40 -6.35 -6.96 18.26 -2.91 -29.38 -9.65 -7.01 15.55
Peroxisomes 0.65 8.59 7.60 2.91 -5.73 -6.43 6.35 5.22 10.05 -1.24 -0.64 10.09 8.90 10.11 -4.50
Vacuole -5.83 -11.31 -20.99 -10.09 -17.47 -9.01 -15.85 -20.08 -15.92 -9.33 -12.52 -18.34 -28.50 -22.20 -19.31
Vacuole Periphery 0.78 8.60 -1.42 -1.64 -2.81 -3.12 0.83 -2.05 -0.11 -2.35 -2.40 4.48 -2.41 -0.67 -3.66
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description 6-phosphogluconolactonase; protein abundance increases in response to DNA replication stress; SOL4 has a paralog, SOL3, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (42%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Sol4

Sol4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sol4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available