Standard name
Human Ortholog
Description RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0.05 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.05 0 0.07 0 0 0 0 0 0.05 0.05 0.05 0 0 0.1 0.07 – – – 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.05 0 0.07 0 0 0 0 – – – 0 0 0 0 0 0
Nucleus 0.75 0.71 0.67 0.81 0.79 0.8 0.68 0.69 0.65 0.7 0.62 0.66 0.75 0.66 0.69 – – – 0.59 0.59 0.43 0.5 0.44 0.48
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0.7 0.76 0.62 0.37 0.29 0.31 0.48 0.51 0.57 0.54 0.69 0.62 0.49 0.32 0.35 – – – 0.32 0.36 0.5 0.35 0.45 0.41
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0.06 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 1 1 0 1 0 0 0 0 0 – – – 0 1 0 3 1 4
Bud Neck 0 1 0 0 0 0 1 1 1 2 1 0 1 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 4 0 8 4 6 1 0 2 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 1 2 4 2 10 6 8 11 12 14 10 5 6 19 16 – – – 1 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 1 0 0 0
Endosome 0 1 0 0 1 1 1 2 0 0 0 0 1 3 2 – – – 1 0 0 0 1 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 – – – 0 0 0 0 0 0
Mitochondria 0 1 0 0 1 1 9 3 12 7 16 5 1 0 0 – – – 0 0 0 0 2 1
Nucleus 15 119 41 107 181 173 212 182 164 197 135 134 131 123 150 – – – 33 104 41 38 121 110
Nuclear Periphery 0 0 0 0 0 0 2 1 1 0 0 0 0 0 0 – – – 0 0 0 0 1 0
Nucleolus 14 127 38 49 66 66 152 135 142 150 151 126 86 60 75 – – – 18 62 48 27 124 93
Peroxisomes 0 1 0 0 0 0 1 0 0 0 0 0 0 0 4 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 2 1 0 0 0 0 1 5 4 – – – 0 1 0 1 0 1
Vac/Vac Membrane 0 4 1 2 6 1 0 1 1 1 1 1 1 3 7 – – – 0 4 0 3 15 12
Unique Cell Count 20 168 61 132 229 216 314 264 251 280 219 203 175 187 217 57 176 97 77 276 228
Labelled Cell Count 30 256 84 160 265 248 393 338 341 376 320 272 228 215 259 57 176 97 77 276 228


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 15.1 26.1 18.1 16.8 16.5 14.1 13.0 13.6 12.3 12.4 11.3 12.4 18.7 18.9 19.6 – – – 17.4 20.6 22.4
Std Deviation (1e-4) 4.8 6.2 5.5 4.3 4.0 3.6 3.7 3.6 3.7 4.0 3.2 3.5 5.8 6.5 7.1 – – – 6.2 5.7 7.2
Intensity Change (Log2) – – – -0.1 -0.14 -0.36 -0.47 -0.42 -0.56 -0.55 -0.68 -0.54 0.05 0.06 0.11 – – – -0.06 0.18 0.31

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70001020WT3HU80HU120HU16001020WT301020WT1AF100AF140AF18001020
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0.8 0 – – –
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nucleus 2.1 1.9 2.1 0 0.3 -0.3 0.5 -0.8 -0.2 1.2 -0.2 0.3 – – –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nucleolus -3.3 -4.8 -4.5 -2.0 -1.6 -0.8 -1.2 1.0 0 -1.8 -4.2 -3.9 – – –
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 – – –
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 13.295 16.5946 14.7211 14.4105 13.7248 14.7298 15.2336 17.3373 16.4744 14.0084 12.7878 16.1865 15.0051 20.0802 19.4052 19.5747 17.7278 19.1686
Actin 0.028 0 0.0202 0 0 0.0003 0.0452 0 0.0058 0.0525 0.0097 0.0049 0.0286 0 0.0117 0 0.0046 0.0015
Bud 0.0007 0 0.0004 0 0.0001 0.0001 0.0007 0.0002 0.0003 0.0005 0.0002 0 0.0017 0 0.0006 0 0.0001 0.0001
Bud Neck 0.0022 0 0.0082 0 0.0001 0.0003 0.0009 0.0001 0.0002 0.0015 0.0006 0.0002 0.0006 0 0.0004 0 0.0001 0.0001
Bud Periphery 0.0008 0 0.0004 0 0.0001 0.0001 0.0008 0.0002 0.0004 0.0011 0.0002 0.0001 0.0025 0 0.0009 0 0.0001 0.0001
Bud Site 0.0031 0 0.0026 0 0.0002 0.0002 0.0027 0.0019 0.0006 0.0006 0.0004 0.0001 0.005 0 0.0017 0 0.0001 0
Cell Periphery 0.0005 0 0.0003 0 0.0003 0.0001 0.0005 0.0001 0.0003 0.0003 0.0002 0 0.0005 0 0.0001 0 0.0001 0.0001
Cytoplasm 0.0112 0 0.0008 0 0 0.0001 0.0098 0.0006 0.0008 0.0002 0.0005 0 0.0021 0.0019 0.0015 0 0.0002 0.0001
Cytoplasmic Foci 0.0147 0 0.0048 0 0.0001 0.0078 0.0314 0 0.0043 0.0012 0.012 0.0018 0.0157 0.0001 0.0043 0 0.0002 0.0001
Eisosomes 0.0002 0 0.0002 0 0 0 0.0003 0 0.0001 0.0004 0.0001 0.0001 0.0004 0 0.0001 0 0 0
Endoplasmic Reticulum 0.0044 0 0.0006 0 0 0.0001 0.0025 0 0.0004 0.0006 0.0004 0 0.0041 0.0004 0.0013 0 0.0013 0.0003
Endosome 0.057 0 0.0023 0 0 0.0018 0.0198 0 0.0069 0.0017 0.0108 0.0002 0.0111 0.0016 0.0139 0 0.0032 0.0022
Golgi 0.0087 0 0.0027 0 0 0.0008 0.009 0 0.0015 0.0042 0.0052 0.0003 0.003 0 0.0103 0 0.0007 0.0006
Lipid Particles 0.0256 0 0.0078 0 0.0001 0.005 0.0195 0 0.0068 0.0031 0.0254 0.0011 0.006 0 0.0034 0 0.0003 0.0002
Mitochondria 0.0244 0.0001 0.0047 0.0311 0.0523 0.0017 0.0077 0.0001 0.0073 0.0232 0.0026 0.0008 0.0145 0.0002 0.0067 0 0.0036 0.0025
None 0.0046 0 0.0005 0 0 0.0001 0.0047 0 0.0006 0.0002 0.0009 0.0002 0.0044 0.0002 0.0007 0 0.0002 0.0001
Nuclear Periphery 0.0154 0.0006 0.0089 0.0001 0.0001 0.0036 0.008 0.0004 0.0012 0.0007 0.0033 0.0002 0.0451 0.0027 0.014 0 0.0527 0.0039
Nucleolus 0.1628 0.0657 0.085 0.0592 0.5803 0.3429 0.1461 0.0688 0.0747 0.051 0.5713 0.307 0.1608 0.0786 0.0665 0.0395 0.506 0.299
Nucleus 0.5829 0.9334 0.8402 0.9092 0.3649 0.6326 0.6604 0.9269 0.8833 0.8379 0.2943 0.6788 0.6586 0.9135 0.849 0.9604 0.4237 0.6882
Peroxisomes 0.0143 0 0.0055 0 0.0001 0.0008 0.0069 0 0.0013 0.0177 0.0422 0.0005 0.0025 0 0.0038 0 0.0001 0
Punctate Nuclear 0.0216 0.0001 0.001 0.0001 0.0005 0.0006 0.0188 0.0002 0.0012 0.0003 0.019 0.0033 0.0248 0.0001 0.0048 0 0.0011 0.0004
Vacuole 0.0139 0 0.0011 0 0.0004 0.0005 0.0019 0.0003 0.0014 0.0005 0.0004 0.0001 0.0024 0.0004 0.0027 0 0.0002 0.0002
Vacuole Periphery 0.0031 0 0.0018 0 0.0005 0.0005 0.0023 0.0001 0.0006 0.0007 0.0003 0.0001 0.0054 0.0003 0.0015 0 0.0013 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 40.9309 34.013 32.1225 49.9281 42.6044 33.418 39.6012 49.236 43.8749 48.7322
Translational Efficiency 1.9364 2.7428 2.4088 1.5168 1.9551 2.4137 2.6404 1.7589 1.8058 1.9662

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
50 264 217 1203 1699 1456 406 939 1749 1720 623 2142

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1691.42 1846.77 2305.03 1760.14 1560.27 1831.73 2062.99 2008.51 1564.02 1834.04 2147.30 1869.02
Standard Deviation 392.78 436.70 424.70 452.21 373.48 398.02 364.90 571.72 374.68 404.23 403.60 522.80
Intensity Change Log 2 — 0.126769 0.446551 0.057455 — 0.231411 0.402941 0.364330 — 0.177928 0.425790 0.212858

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000717 0.000735 0.000968 0.001284 0.000590 0.000689 0.001039 0.001063 0.000594 0.000696 0.001014 0.001187
Bud Neck 0.003458 0.006249 0.008081 0.019467 0.003467 0.005131 0.008596 0.016437 0.003466 0.005302 0.008416 0.018139
Bud Site 0.000894 0.001378 0.001033 0.007076 0.000650 0.000850 0.001183 0.003662 0.000657 0.000931 0.001131 0.005579
Cell Periphery 0.000038 0.000095 0.000021 0.000332 0.000052 0.000072 0.000027 0.000209 0.000052 0.000075 0.000025 0.000278
Cytoplasm 0.000034 0.000118 0.000020 0.003334 0.000593 0.000343 0.000052 0.002995 0.000577 0.000309 0.000041 0.003185
Cytoplasmic Foci 0.000792 0.000790 0.000633 0.005631 0.000384 0.000405 0.000743 0.004589 0.000396 0.000465 0.000705 0.005174
Eisosomes 0.000176 0.000167 0.000225 0.000086 0.000152 0.000210 0.000216 0.000070 0.000152 0.000204 0.000219 0.000079
Endoplasmic Reticulum 0.000335 0.000393 0.000196 0.000789 0.000261 0.000268 0.000332 0.000423 0.000263 0.000287 0.000285 0.000629
Endosome 0.000014 0.000118 0.000006 0.005490 0.000072 0.000040 0.000011 0.001920 0.000070 0.000052 0.000009 0.003925
Golgi 0.000054 0.000105 0.000089 0.002554 0.000055 0.000069 0.000119 0.003051 0.000055 0.000074 0.000108 0.002772
Lipid Particles 0.000005 0.000085 0.000007 0.001057 0.000019 0.000026 0.000011 0.000361 0.000019 0.000035 0.000009 0.000752
Mitochondria 0.001348 0.001671 0.002557 0.005817 0.001160 0.001567 0.002295 0.005058 0.001165 0.001583 0.002386 0.005484
Mitotic Spindle 0.000122 0.002926 0.000104 0.013235 0.000342 0.001771 0.000324 0.020997 0.000335 0.001948 0.000247 0.016638
None 0.000600 0.000764 0.000682 0.004046 0.001000 0.001124 0.000911 0.002486 0.000989 0.001069 0.000832 0.003362
Nuclear Periphery 0.000061 0.000067 0.000029 0.000915 0.000048 0.000058 0.000049 0.000901 0.000048 0.000060 0.000042 0.000909
Nuclear Periphery Foci 0.000008 0.000368 0.000003 0.001505 0.000052 0.000089 0.000008 0.000767 0.000051 0.000132 0.000006 0.001181
Nucleolus 0.215302 0.158224 0.123001 0.059274 0.132940 0.142338 0.151847 0.059682 0.135294 0.144777 0.141799 0.059453
Nucleus 0.754614 0.810133 0.832356 0.857856 0.851421 0.837649 0.800498 0.868980 0.848653 0.833425 0.811595 0.862732
Peroxisomes 0.020989 0.011333 0.029404 0.003918 0.006184 0.005824 0.031154 0.003495 0.006607 0.006670 0.030544 0.003733
Vacuole 0.000205 0.003311 0.000233 0.004001 0.000217 0.000623 0.000276 0.001622 0.000217 0.001036 0.000261 0.002958
Vacuole Periphery 0.000233 0.000971 0.000352 0.002335 0.000343 0.000853 0.000312 0.001232 0.000340 0.000871 0.000326 0.001851

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.14 -2.80 -4.13 -4.13 -2.41 -1.97 -11.38 -10.13 -7.21 -1.59 -2.25 -12.47 -10.02 -7.54 -2.63
Bud Neck -1.60 -3.44 -8.40 -7.56 -7.55 -5.48 -10.47 -13.19 -11.83 -7.84 -5.78 -13.23 -16.51 -14.46 -10.36
Bud Site -0.51 -0.28 -4.21 -4.17 -4.77 -0.41 -2.88 -5.19 -4.99 -4.26 -0.68 -2.64 -6.71 -6.46 -6.05
Cell Periphery -0.69 0.59 -4.64 -2.65 -6.93 -0.77 1.62 -4.05 -3.21 -4.99 -0.94 1.80 -6.68 -5.16 -8.49
Cytoplasm -1.22 0.54 -3.34 -3.27 -3.36 0.81 1.51 -2.00 -2.66 -3.06 0.88 1.54 -3.07 -3.98 -4.42
Cytoplasmic Foci 0.04 0.29 -3.00 -3.54 -4.14 0.39 -1.16 -3.12 -3.29 -2.83 0.16 -1.05 -5.06 -5.37 -4.89
Eisosomes 0.31 -0.83 1.74 3.18 9.79 -4.68 -6.40 9.56 12.28 15.00 -4.28 -7.31 9.51 12.33 17.60
Endoplasmic Reticulum -0.42 1.82 -3.73 -2.40 -5.40 -0.30 -3.05 -6.39 -6.16 -4.41 -0.73 -1.69 -6.41 -5.84 -5.95
Endosome -1.56 0.85 -4.17 -4.05 -4.18 0.72 1.45 -2.76 -2.83 -2.89 0.42 1.51 -4.85 -4.89 -4.97
Golgi -1.46 -2.78 -3.66 -3.54 -3.57 -0.62 -6.16 -2.09 -2.07 -2.01 -1.01 -5.85 -3.63 -3.60 -3.51
Lipid Particles -1.76 -1.18 -1.65 -1.47 -1.65 -0.27 0.82 -2.80 -2.77 -2.92 -0.82 0.94 -2.10 -2.05 -2.14
Mitochondria -0.53 -3.27 -4.55 -4.05 -3.13 -3.63 -9.25 -3.84 -3.43 -2.58 -3.50 -10.50 -6.38 -5.67 -4.16
Mitotic Spindle -1.43 0.14 -5.54 -3.06 -5.56 -1.53 -0.22 -5.89 -5.40 -5.88 -1.91 0.22 -7.90 -6.68 -7.96
None -1.39 -1.15 -5.59 -5.26 -5.44 -0.25 0.39 -4.37 -3.81 -6.70 -0.15 0.67 -5.33 -5.23 -7.09
Nuclear Periphery 0.03 0.64 -4.52 -4.75 -5.08 -0.63 -0.65 -3.66 -3.62 -3.64 -0.75 0.29 -5.91 -5.82 -5.93
Nuclear Periphery Foci -1.60 1.51 -2.29 -1.43 -2.30 -0.42 1.88 -3.73 -3.46 -4.11 -1.10 1.95 -3.07 -2.79 -3.28
Nucleolus 1.77 2.97 5.22 8.29 6.74 -1.45 -2.84 11.94 12.82 10.24 -1.57 -1.63 14.55 16.18 12.36
Nucleus -1.60 -2.25 -3.33 -3.47 -2.50 1.93 5.47 -0.57 -2.02 -5.24 2.29 5.09 -1.43 -3.57 -6.00
Peroxisomes 2.31 -1.68 4.44 5.35 6.90 0.69 -8.88 5.30 4.78 9.81 -0.14 -10.60 6.61 7.07 12.01
Vacuole -1.62 -0.51 -3.75 -0.38 -3.72 -1.89 -1.69 -4.58 -3.09 -4.37 -2.39 -1.49 -4.93 -3.09 -4.81
Vacuole Periphery -1.59 -1.67 -2.86 -1.13 -2.64 -3.62 0.46 -1.65 -0.46 -1.70 -3.82 0.11 -3.14 -1.51 -3.16
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit
Localization
Cell Percentages nucleus (84%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-2

Rpb3

Rpb3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpb3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available