Standard name
Human Ortholog
Description Mitochondrial matrix protein; required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase; null mutant temperature sensitive growth on glycerol is suppressed by multicopy expression of Odc1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0.08 0.11 0 0 0 0 0 0
Bud – 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Bud Neck – 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site – 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.06 0 0.1 0 0 0 0 0 0
Cytoplasm – 0 0.07 0.07 0.05 0 – 0 0 0 0 0 0 0.06 0.07 0.12 0.32 0.1 0 0 0 0 0 0
Endoplasmic Reticulum – 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome – 0 0 0 0.06 0 – 0 0 0 0 0 0 0.1 0.09 0.22 0.08 0.13 0.08 0 0.08 0.06 0.08 0.06
Golgi – 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.11 0.05 0.13 0 0.07 0 0 0.06 0.07
Mitochondria – 0.83 0.92 0.94 0.89 0.94 – 0.92 0.94 0.94 0.97 0.97 0.88 0.81 0.67 0.09 0.18 0.1 0.76 0.72 0.73 0.71 0.69 0.66
Nucleus – 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.08 0 0.05 0 0 0 0 0 0
Nuclear Periphery – 0 0 0 0 0.08 – 0.06 0.1 0.08 0.07 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus – 0 0 0 0 0.05 – 0.09 0.06 0.05 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes – 0 0 0 0.05 0 – 0 0 0 0 0 0 0.05 0.08 0.12 0.11 0.12 0 0 0 0.06 0.05 0.05
SpindlePole – 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.08 0.16 0.11 0 0 0 0 0 0
Vac/Vac Membrane – 0.22 0.05 0 0.05 0.06 – 0 0 0 0 0 0.1 0.09 0.12 0.22 0.16 0.24 0.1 0.08 0 0.05 0.05 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 1 3 1 0 0 – 0 0 0 0 0 5 4 0 3 3 9 0 3 3 2 3 7
Bud – 2 8 10 10 14 – 33 23 30 37 31 4 4 0 2 0 5 0 0 2 1 0 1
Bud Neck – 0 1 0 0 0 – 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 1 4
Bud Site – 0 5 1 1 3 – 9 9 10 9 20 0 0 0 0 0 0 – – – – – –
Cell Periphery – 6 2 4 3 3 – 2 3 5 7 7 2 6 8 4 0 8 0 0 0 0 0 0
Cytoplasm – 6 17 20 17 16 – 13 13 12 6 4 5 17 16 8 12 8 0 1 1 2 1 2
Endoplasmic Reticulum – 1 5 2 1 3 – 6 2 1 5 3 4 8 6 1 1 2 0 1 0 1 0 0
Endosome – 6 0 1 18 1 – 11 2 1 2 0 6 26 21 14 3 11 4 5 19 10 20 17
Golgi – 7 0 2 0 0 – 1 0 0 0 0 0 7 11 7 2 11 1 12 2 6 15 19
Mitochondria – 142 215 251 285 512 – 887 588 737 703 826 147 217 149 6 7 8 42 130 174 121 173 182
Nucleus – 1 2 1 4 6 – 28 5 15 6 3 1 1 1 5 1 4 0 0 0 0 0 2
Nuclear Periphery – 1 1 4 3 44 – 58 63 61 47 60 0 1 3 0 1 1 0 0 2 1 1 1
Nucleolus – 0 0 0 6 28 – 85 40 42 31 51 1 2 1 0 0 1 0 0 1 1 1 2
Peroxisomes – 2 0 0 16 3 – 21 6 6 6 8 7 13 17 8 4 10 0 6 10 10 11 13
SpindlePole – 0 4 1 7 5 – 33 11 16 18 23 6 3 2 5 6 9 0 1 2 1 4 1
Vac/Vac Membrane – 37 11 6 17 30 – 36 20 25 18 20 17 24 26 14 6 20 5 14 8 8 13 19
Unique Cell Count 171 234 267 319 543 965 626 782 722 852 167 269 223 64 38 84 56 182 239 172 252 278
Labelled Cell Count 212 274 304 388 668 1223 786 963 895 1056 205 333 261 77 46 107 56 182 239 172 252 278


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 6.0 3.6 4.0 5.0 4.2 – 4.4 4.1 4.3 4.2 4.2 4.8 5.6 5.5 6.6 5.9 6.3 5.4 5.6 5.6
Std Deviation (1e-4) – 1.2 0.8 1.5 1.5 1.1 – 1.0 1.2 1.0 1.1 1.0 0.8 1.1 0.9 1.5 1.2 1.4 1.0 1.3 1.3
Intensity Change (Log2) – – – 0.19 0.48 0.25 – 0.31 0.21 0.28 0.24 0.24 0.44 0.66 0.62 0.89 0.74 0.81 0.6 0.66 0.66

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 -0.2 0 – 0 0 0 0 0 0 -1.4 0 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.1 -0.9 -2.7 – -5.2 -3.7 -4.6 -5.6 0 -1.9 -0.4 0 1.3 0 0.7
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 0 0.6 0.4 0 0 0
Endosome 0 3.7 0 – 0 0 0 0 0 0 4.9 4.8 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 3.4 0 0 0
Mitochondria 0 -1.0 0 – 0 0 0 0 0 0 -3.6 -6.7 -13.4 -10.8 -14.1
Nucleus 0 0 0 – 1.8 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 3.5 0 – 0 0 0 0 0 0 3.4 4.3 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vacuole -1.5 0.3 0.5 – -0.7 -1.1 -1.1 -1.7 -1.9 2.1 1.9 2.7 4.4 0 5.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.3118 1.0849 0.9522 0.8733 0.3319 1.0144 0.6268 0.892 0.7151 0.6117 0.7435 0.5819 2.0556 2.0606 1.725 1.9771 1.2504 1.464
Actin 0.0483 0.009 0.0216 0.0053 0.0032 0.0195 0.0373 0.0069 0.0118 0.0302 0.0582 0.0128 0.0213 0.018 0.0122 0.0614 0.01 0.0039
Bud 0.0035 0.0016 0.0011 0.0008 0.0012 0.0007 0.004 0.0091 0.005 0.0067 0.0016 0.0006 0.0007 0.0028 0.0019 0.0027 0.0097 0.0005
Bud Neck 0.0037 0.0008 0.0016 0.0003 0.0008 0.0073 0.001 0.0013 0.0016 0.0024 0.0009 0.002 0.0011 0.0019 0.0021 0.0096 0.0014 0.0009
Bud Periphery 0.0049 0.002 0.0016 0.0019 0.0036 0.0014 0.0033 0.0094 0.0084 0.0157 0.0028 0.0018 0.0015 0.0042 0.0061 0.0119 0.0075 0.0017
Bud Site 0.0098 0.0174 0.0068 0.0006 0.001 0.0011 0.0028 0.04 0.0144 0.0077 0.0041 0.0008 0.0034 0.0309 0.0122 0.0042 0.0023 0.0007
Cell Periphery 0.0024 0.0005 0.0009 0.0002 0.0007 0.0003 0.0006 0.0026 0.0012 0.0015 0.0002 0.0004 0.0011 0.0013 0.0019 0.002 0.0005 0.0005
Cytoplasm 0.0122 0.0181 0.0159 0.0074 0.0033 0.0116 0.0236 0.0134 0.0061 0.0106 0.0011 0.0167 0.0158 0.0177 0.0201 0.051 0.0125 0.0041
Cytoplasmic Foci 0.045 0.08 0.042 0.0272 0.0438 0.0524 0.0735 0.048 0.0463 0.0661 0.0564 0.0648 0.0621 0.0665 0.055 0.0638 0.0853 0.0373
Eisosomes 0.0007 0.0003 0.0008 0.0002 0.0003 0.0005 0.0007 0.0009 0.0005 0.0008 0.0004 0.0003 0.0011 0.0028 0.0007 0.0005 0.0005 0.0002
Endoplasmic Reticulum 0.0078 0.0038 0.002 0.001 0.0016 0.0027 0.0035 0.0014 0.0016 0.0005 0.0006 0.0024 0.0073 0.0016 0.0023 0.002 0.0009 0.0006
Endosome 0.0817 0.0964 0.083 0.1284 0.1863 0.0774 0.1393 0.0605 0.0539 0.0378 0.1033 0.0672 0.1207 0.0667 0.0717 0.0394 0.125 0.0594
Golgi 0.0515 0.0845 0.0501 0.0603 0.1385 0.0702 0.0833 0.0511 0.0424 0.0322 0.0866 0.054 0.0484 0.0462 0.0427 0.0466 0.1346 0.0517
Lipid Particles 0.032 0.024 0.0231 0.0043 0.0319 0.0325 0.0612 0.0202 0.0203 0.0044 0.0323 0.0169 0.0425 0.0207 0.0221 0.0037 0.0084 0.0229
Mitochondria 0.5808 0.5512 0.6403 0.6488 0.5497 0.6443 0.432 0.6482 0.6868 0.6871 0.5427 0.6347 0.5464 0.5377 0.6287 0.6201 0.4974 0.7095
None 0.0191 0.0293 0.0107 0.0536 0.0006 0.018 0.0321 0.0292 0.0205 0.0385 0.0007 0.0193 0.0327 0.0876 0.0393 0.036 0.0386 0.014
Nuclear Periphery 0.0163 0.0011 0.0028 0.0005 0.0021 0.0021 0.0087 0.0005 0.0019 0.0002 0.0041 0.0046 0.0082 0.0009 0.0018 0.0007 0.0015 0.0008
Nucleolus 0.0012 0.0008 0.0006 0.0002 0.0004 0.001 0.0017 0.0013 0.0018 0.0007 0.0004 0.0004 0.0013 0.0009 0.001 0.001 0.0015 0.0004
Nucleus 0.0068 0.0007 0.0013 0.0002 0.0006 0.0006 0.0028 0.0019 0.0021 0.0011 0.0005 0.0014 0.0204 0.0008 0.0018 0.0014 0.0013 0.0004
Peroxisomes 0.0489 0.0682 0.0768 0.0476 0.0124 0.0472 0.0667 0.0425 0.0563 0.043 0.0871 0.0908 0.0477 0.0819 0.0646 0.0267 0.0472 0.0837
Punctate Nuclear 0.0059 0.0019 0.002 0.0002 0.0003 0.0021 0.0112 0.0023 0.0052 0.0005 0.01 0.001 0.005 0.0006 0.0033 0.0039 0.0044 0.0005
Vacuole 0.01 0.0046 0.0095 0.0062 0.0092 0.0033 0.0063 0.007 0.0082 0.0088 0.0031 0.0039 0.0072 0.0061 0.0054 0.0087 0.0055 0.0034
Vacuole Periphery 0.0076 0.0035 0.0056 0.005 0.0084 0.0038 0.0044 0.0023 0.0039 0.0036 0.0029 0.0032 0.0043 0.0024 0.003 0.0028 0.0039 0.0029

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2.3577 2.1076 14.0756 10.2732 9.1706 18.8512 13.8517 20.1363 23.2743 13.2868
Translational Efficiency 11.205 9.984 1.4646 2.635 2.744 1.7428 2.4027 1.8084 1.4289 2.6888

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1944 2138 1628 1435 1898 1968 324 1251 3842 4106 1952 2686

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 692.21 770.00 997.99 944.64 696.36 745.00 949.91 949.40 694.26 758.02 990.01 946.86
Standard Deviation 88.34 103.59 136.41 141.93 96.72 103.20 127.93 122.08 92.60 104.15 136.22 133.07
Intensity Change Log 2 — 0.153649 0.527816 0.448555 — 0.097407 0.447957 0.447183 — 0.125718 0.488320 0.447867

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000334 0.001775 0.003304 0.018045 0.000598 0.000755 0.005246 0.011976 0.000464 0.001286 0.003626 0.015218
Bud Neck 0.015921 0.005162 0.002948 0.002498 0.008471 0.009394 0.013130 0.004339 0.012241 0.007190 0.004638 0.003355
Bud Site 0.012297 0.010187 0.019554 0.035276 0.009701 0.006870 0.057672 0.036160 0.011015 0.008597 0.025881 0.035688
Cell Periphery 0.000228 0.000352 0.000233 0.001612 0.000823 0.000373 0.000432 0.001409 0.000522 0.000362 0.000266 0.001517
Cytoplasm 0.032942 0.005134 0.004693 0.005247 0.005552 0.006449 0.007841 0.007325 0.019411 0.005764 0.005215 0.006214
Cytoplasmic Foci 0.121940 0.058392 0.094495 0.035533 0.024860 0.056478 0.082259 0.036133 0.073981 0.057475 0.092464 0.035813
Eisosomes 0.000108 0.000083 0.000070 0.000141 0.000071 0.000095 0.000118 0.000138 0.000090 0.000089 0.000078 0.000140
Endoplasmic Reticulum 0.001264 0.000220 0.001480 0.001109 0.000598 0.000152 0.001793 0.001128 0.000935 0.000187 0.001532 0.001118
Endosome 0.074966 0.082043 0.096303 0.050498 0.047677 0.082494 0.112741 0.058482 0.061485 0.082259 0.099032 0.054216
Golgi 0.096550 0.146089 0.160288 0.087253 0.065358 0.136221 0.082367 0.086833 0.081141 0.141360 0.147354 0.087057
Lipid Particles 0.013586 0.002526 0.002227 0.000759 0.003580 0.005016 0.002245 0.000529 0.008643 0.003719 0.002230 0.000652
Mitochondria 0.515064 0.599711 0.410187 0.653237 0.779227 0.619156 0.337878 0.644322 0.645564 0.609031 0.398185 0.649085
Mitotic Spindle 0.010213 0.019005 0.074560 0.029501 0.003213 0.009514 0.098653 0.024074 0.006755 0.014456 0.078559 0.026973
None 0.002425 0.000321 0.000319 0.000243 0.001258 0.000647 0.000208 0.000204 0.001849 0.000477 0.000300 0.000225
Nuclear Periphery 0.000439 0.000076 0.000818 0.000099 0.000072 0.000044 0.000207 0.000069 0.000258 0.000061 0.000717 0.000085
Nuclear Periphery Foci 0.000619 0.000128 0.001702 0.000323 0.000145 0.000090 0.000744 0.000110 0.000385 0.000109 0.001543 0.000224
Nucleolus 0.003225 0.000452 0.000470 0.000049 0.000526 0.000440 0.000755 0.000080 0.001891 0.000446 0.000517 0.000063
Nucleus 0.009435 0.000622 0.001092 0.000104 0.002786 0.000753 0.003251 0.000203 0.006150 0.000685 0.001450 0.000150
Peroxisomes 0.031714 0.045691 0.028587 0.052405 0.022336 0.048275 0.139283 0.062748 0.027081 0.046930 0.046961 0.057222
Vacuole 0.032173 0.012693 0.048107 0.013409 0.008916 0.008798 0.035383 0.012066 0.020684 0.010826 0.045995 0.012784
Vacuole Periphery 0.024558 0.009338 0.048563 0.012660 0.014232 0.007985 0.017795 0.011673 0.019457 0.008690 0.043456 0.012200

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.84 -7.70 -9.14 -8.25 -7.46 -0.64 -5.63 -7.14 -7.09 -3.72 -3.58 -8.76 -11.57 -10.84 -8.78
Bud Neck 7.20 9.20 9.98 3.63 0.96 -0.54 -2.30 2.91 3.35 4.56 4.53 7.49 9.17 4.72 2.10
Bud Site 1.61 -4.57 -8.12 -8.75 -5.16 2.17 -7.45 -8.39 -9.72 3.13 2.60 -8.63 -11.68 -13.05 -3.77
Cell Periphery -0.74 -0.23 -3.40 -2.87 -3.38 1.60 1.46 -1.46 -3.25 -3.17 0.98 1.94 -3.43 -4.17 -4.82
Cytoplasm 12.04 12.48 12.10 0.05 -0.68 -0.40 -1.17 -1.32 -0.93 0.43 10.11 10.56 9.90 -0.68 -1.34
Cytoplasmic Foci 15.89 6.08 21.59 8.30 15.95 -12.89 -9.01 -4.32 6.98 7.03 6.72 -5.11 15.30 10.82 17.96
Eisosomes 3.84 7.13 -3.70 -6.34 -8.52 -3.29 -4.84 -6.16 -3.58 -1.21 0.24 2.61 -7.18 -6.86 -8.74
Endoplasmic Reticulum 4.04 -0.85 0.46 -5.41 1.69 1.85 -3.02 -1.33 -3.06 1.62 4.22 -2.78 -0.78 -5.40 1.99
Endosome -1.89 -5.46 6.85 8.53 12.01 -8.95 -7.57 -2.87 5.58 6.17 -7.65 -11.37 2.80 9.95 13.24
Golgi -9.27 -11.24 1.68 9.96 11.79 -13.65 -2.10 -4.21 8.44 -0.67 -16.11 -14.28 -1.61 13.03 12.06
Lipid Particles 9.26 9.46 11.46 3.92 3.50 -1.28 1.34 4.66 4.75 3.49 5.98 8.44 12.16 6.02 4.47
Mitochondria -7.88 8.98 -11.30 -4.41 -19.02 15.45 21.16 11.05 -1.96 -13.91 4.58 25.61 -0.47 -4.55 -24.02
Mitotic Spindle -4.75 -16.31 -7.49 -3.80 9.99 -5.52 -9.27 -9.74 -6.19 7.09 -6.96 -19.67 -11.91 -6.78 13.03
None 4.59 4.70 4.87 1.15 4.67 1.37 2.89 2.92 1.63 0.42 4.29 5.36 5.63 1.90 5.75
Nuclear Periphery 5.14 -2.61 4.98 -0.86 5.58 2.07 -3.66 0.21 -2.16 3.81 5.38 -4.08 4.86 -1.62 5.89
Nuclear Periphery Foci 2.31 -2.45 1.04 -1.33 3.05 1.83 -3.73 1.30 -0.93 4.05 2.58 -3.18 1.14 -1.44 3.58
Nucleolus 4.42 5.01 5.98 2.15 3.78 0.62 -0.67 2.35 3.23 2.78 4.30 4.44 6.41 3.19 4.47
Nucleus 7.26 6.69 7.82 3.44 3.36 2.48 -0.46 3.18 3.11 2.54 7.38 5.72 8.24 4.66 4.10
Peroxisomes -4.27 1.08 -4.90 -1.42 -5.35 -8.02 -9.61 -8.11 -2.67 5.97 -8.62 -6.10 -9.33 -2.89 -2.41
Vacuole 10.00 -5.99 8.67 -0.56 14.22 0.14 -6.05 -2.40 -2.60 5.26 8.86 -12.10 5.99 -2.05 16.04
Vacuole Periphery 11.04 -9.39 6.80 -2.48 14.08 6.44 -1.02 1.81 -3.08 1.76 12.64 -11.41 6.38 -3.88 14.67
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial matrix protein; required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase; null mutant temperature sensitive growth on glycerol is suppressed by multicopy expression of Odc1p
Localization
Cell Percentages mitochondrion (94%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Fmc1

Fmc1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Fmc1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available