Standard name
Human Ortholog
Description Specific chaperone for ribosomal protein Rpl10p; binds nascent Rpl10p during translation; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.12 0.1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.48 0.89 0.48 0.49 0.32 0.47 0.42 0.39 0.51 0.33 0.35 0.47 0.67 0.55 0.6 0.29 0.32 0.25 0.49 0.35 0.4 0.38 0.27 0.28
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.08
Golgi 0 0 0 0.08 0.1 0 0 0.05 0.06 0 0 0 0 0.06 0.11 0.19 0.17 0.24 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.06 0.1 0.09 0.08 0.15 0.24 0.2 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0.24 0.09 0.12 0.14 0.13 0.14 0.1 0.15 0.09 0 0.06 0.06 0.07 0 0 0.39 0.47 0.35 0.42 0.31 0.26
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.08 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.13
Vac/Vac Membrane 0.63 0.16 0.63 0.41 0.61 0.44 0.38 0.4 0.32 0.43 0.34 0.29 0.55 0.57 0.49 0.67 0.66 0.62 0.06 0.11 0.14 0.08 0.1 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 5 0 1 2 2 1 0 0 0 0 1 0 0 0 2 0 1 1
Bud 0 0 0 0 0 1 3 5 1 5 2 3 0 0 0 0 1 0 0 4 7 24 92 69
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 3
Bud Site 0 0 0 0 0 0 0 1 0 1 2 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 1 0 1 3 1 3 0 1 2 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 35 192 153 64 77 156 161 186 152 125 109 120 288 334 362 78 87 53 41 79 135 150 201 187
Endoplasmic Reticulum 0 0 3 0 0 1 3 12 4 5 3 6 2 2 1 13 13 9 0 2 5 2 1 6
Endosome 0 0 0 0 1 0 3 0 0 1 1 0 1 1 1 0 0 0 0 0 3 4 43 53
Golgi 2 0 10 10 25 12 4 23 17 2 4 5 8 37 66 51 45 52 0 0 0 1 1 2
Mitochondria 0 0 1 0 2 19 39 44 23 58 77 51 0 0 1 3 0 2 0 0 2 0 0 2
Nucleus 0 6 11 31 23 41 54 63 42 37 46 24 11 36 36 18 4 9 33 105 118 163 235 170
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 2 5 2 6 6
Nucleolus 1 1 0 0 1 1 3 4 0 7 4 2 1 1 0 8 14 17 0 0 1 2 12 8
Peroxisomes 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 3
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 5 69 85
Vac/Vac Membrane 46 35 201 53 148 144 143 194 97 165 108 74 239 349 298 182 180 133 5 25 47 29 75 60
Unique Cell Count 73 216 317 130 243 330 379 480 299 380 315 258 433 607 604 271 272 216 86 227 340 392 759 669
Labelled Cell Count 84 234 379 158 278 376 419 535 338 411 358 289 553 761 766 353 345 275 86 227 340 392 759 669


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 21.7 30.7 23.9 20.3 18.7 16.1 14.7 14.8 14.2 13.6 13.3 13.0 23.8 23.0 20.3 33.7 32.1 34.9 23.2 23.7 23.1
Std Deviation (1e-4) 4.8 5.0 5.2 5.4 4.7 3.9 3.4 3.7 3.5 3.5 3.7 3.2 8.6 8.1 7.6 11.2 10.1 9.8 8.4 8.9 9.2
Intensity Change (Log2) – – – -0.24 -0.35 -0.57 -0.7 -0.69 -0.75 -0.81 -0.84 -0.88 -0.0 -0.05 -0.23 0.5 0.43 0.55 -0.04 -0.01 -0.05

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700010203040WT3HU80HU120HU160010203040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3010203040WT1AF100AF140AF180010203040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.2 -4.0 -0.3 -1.5 -2.7 0.6 -4.1 -3.5 -0.4 5.0 2.0 3.4 -4.8 -4.0 -5.5
Endoplasmic Reticulum 0 0 0 0 1.6 0 0 0 0 0 0 0 2.9 2.9 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 2.1 3.5 0.3 -2.0 1.1 1.5 -2.7 -1.6 -0.9 -1.2 1.9 4.1 6.2 5.6 7.4
Mitochondria 0 0 4.0 5.6 5.3 4.7 7.1 9.2 8.1 0 0 0 0 0 0
Nucleus 6.7 2.9 4.2 4.9 4.6 4.7 3.3 4.9 2.9 -0.7 1.6 1.6 1.8 -1.5 0.4
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 4.1 5.1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -4.4 -0.6 -5.0 -6.7 -6.4 -7.7 -5.3 -7.3 -8.3 -2.3 -1.7 -4.1 1.0 0.7 -0.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 21.6944 28.0211 24.9157 21.6141 23.0447 24.5591 18.6267 27.2651 23.8677 19.585 25.2234 23.8229 25.164 29.2112 27.9901 26.0021 26.343 26.8448
Actin 0.0112 0.0001 0.0007 0.0008 0.0086 0.0001 0.0274 0.0002 0.0168 0.0298 0.0044 0.0022 0.007 0.0002 0.001 0.0001 0.0047 0.0009
Bud 0.0009 0 0.0003 0.0002 0.0032 0.0001 0.0013 0.0001 0.0005 0.0045 0.0001 0.0003 0.0003 0.0001 0.0003 0.0002 0.0002 0.0001
Bud Neck 0.0007 0.0002 0.0003 0.0002 0.0004 0.0008 0.0161 0.0002 0.0005 0.0027 0.0006 0.0012 0.001 0.0002 0.0002 0.0004 0.0005 0.0007
Bud Periphery 0.0005 0 0.0001 0.0001 0.0048 0.0001 0.0015 0 0.0006 0.0109 0.0001 0.0002 0.0002 0 0.0003 0.0001 0.0001 0.0002
Bud Site 0.0016 0.0001 0.0002 0.0002 0.0139 0 0.01 0.0001 0.0005 0.0116 0.0003 0.0004 0.0008 0.0001 0.0031 0.0001 0.0003 0.0001
Cell Periphery 0.0001 0 0 0.0001 0.0002 0 0.0005 0 0.0001 0.0011 0 0 0.0001 0 0 0.0001 0.0001 0.0001
Cytoplasm 0.3836 0.5813 0.5041 0.4783 0.4656 0.4044 0.2438 0.4578 0.3166 0.2568 0.4832 0.3032 0.2696 0.4213 0.322 0.2986 0.3374 0.2253
Cytoplasmic Foci 0.0055 0.0001 0.0006 0.0049 0.0034 0.0001 0.0305 0.0004 0.0063 0.0218 0.0105 0.0015 0.0125 0.0002 0.001 0.0006 0.0022 0.0002
Eisosomes 0.0001 0 0 0 0.0001 0 0.0003 0 0.0001 0.0003 0 0 0.0001 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0044 0.0002 0.0011 0.006 0.0014 0.0016 0.008 0.0003 0.0013 0.0059 0.0005 0.0007 0.0039 0.0006 0.0006 0.0011 0.0024 0.0016
Endosome 0.0042 0.0001 0.0005 0.0103 0.0037 0.0006 0.0257 0.0001 0.0094 0.0157 0.0068 0.0013 0.0108 0.0001 0.0005 0.0007 0.0022 0.0021
Golgi 0.0011 0 0.0001 0.0007 0.0018 0 0.0069 0.0001 0.0015 0.011 0.0058 0.0011 0.0017 0 0.0001 0 0.0021 0.0001
Lipid Particles 0.0016 0 0.0003 0.0013 0.0039 0 0.016 0.0001 0.0042 0.0196 0.0181 0.0035 0.006 0 0.0002 0.0001 0.012 0.0001
Mitochondria 0.0025 0.0001 0.0005 0.0011 0.0015 0.0003 0.0059 0.0003 0.0025 0.0324 0.0011 0.0009 0.0036 0.0002 0.0003 0.0003 0.0053 0.0025
None 0.0029 0.0001 0.0004 0.0134 0.0008 0.0001 0.0106 0.0001 0.0086 0.0043 0.0003 0.0002 0.0036 0.0002 0.0005 0.0006 0.0011 0.0002
Nuclear Periphery 0.0458 0.0154 0.0246 0.0284 0.0183 0.0383 0.0429 0.018 0.0213 0.0229 0.0227 0.0295 0.0365 0.0207 0.0185 0.022 0.0337 0.0302
Nucleolus 0.0005 0.0001 0.0003 0.0002 0.0007 0.0002 0.0044 0.0007 0.0003 0.0015 0.0001 0.0007 0.0016 0.0003 0.0004 0.0012 0.0004 0.0003
Nucleus 0.524 0.4011 0.4628 0.4473 0.4609 0.5493 0.4931 0.5173 0.5968 0.5086 0.4338 0.6464 0.6207 0.554 0.6479 0.6674 0.5913 0.7326
Peroxisomes 0.0004 0 0 0.0001 0.002 0 0.0142 0.0001 0.0058 0.0154 0.0084 0.0011 0.0017 0 0.0002 0 0.0007 0
Punctate Nuclear 0.0055 0.0006 0.0016 0.0013 0.0029 0.0007 0.0323 0.0037 0.0027 0.0085 0.0025 0.0034 0.0101 0.0012 0.0022 0.0032 0.0022 0.001
Vacuole 0.002 0.0003 0.001 0.0037 0.0014 0.0022 0.0061 0.0003 0.0025 0.0096 0.0005 0.0016 0.0062 0.0005 0.0004 0.0026 0.0007 0.0011
Vacuole Periphery 0.0009 0.0001 0.0004 0.0013 0.0004 0.0008 0.0026 0.0001 0.0009 0.005 0.0002 0.0004 0.002 0.0001 0.0001 0.0007 0.0004 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 83.4364 85.2424 79.0669 75.1898 94.3807 58.7135 79.0702 82.5826 72.5236 79.1672
Translational Efficiency 1.9346 1.9883 1.716 1.7925 1.358 1.9107 1.6138 1.1302 1.2559 1.3558

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2018 939 2921 1213 1357 1677 1348 2759 3375 2616 4269 3972

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1620.34 2031.39 2287.85 2581.34 1629.29 1868.62 2303.68 2828.68 1623.94 1927.05 2292.85 2753.15
Standard Deviation 289.87 350.74 382.50 597.64 280.75 331.68 419.16 527.26 286.27 347.53 394.51 561.39
Intensity Change Log 2 — 0.326171 0.497696 0.671824 — 0.197730 0.499697 0.795886 — 0.263202 0.498700 0.735358

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000125 0.000282 0.000069 0.001788 0.000182 0.000216 0.000271 0.000452 0.000148 0.000240 0.000133 0.000860
Bud Neck 0.001841 0.002720 0.002377 0.029129 0.002784 0.002176 0.003771 0.023454 0.002220 0.002371 0.002817 0.025187
Bud Site 0.000523 0.002110 0.000319 0.023422 0.001142 0.001369 0.000950 0.011418 0.000772 0.001635 0.000518 0.015084
Cell Periphery 0.000071 0.000091 0.000046 0.000671 0.000093 0.000080 0.000144 0.000239 0.000080 0.000084 0.000076 0.000371
Cytoplasm 0.251507 0.104096 0.129917 0.069653 0.192028 0.146995 0.038439 0.073212 0.227592 0.131597 0.101032 0.072125
Cytoplasmic Foci 0.000663 0.001361 0.000082 0.008697 0.001216 0.001019 0.000424 0.005010 0.000885 0.001141 0.000190 0.006136
Eisosomes 0.000002 0.000004 0.000002 0.000018 0.000003 0.000003 0.000007 0.000008 0.000002 0.000003 0.000003 0.000011
Endoplasmic Reticulum 0.000423 0.000438 0.000186 0.001987 0.000966 0.000425 0.000352 0.000441 0.000641 0.000430 0.000238 0.000913
Endosome 0.000116 0.000251 0.000033 0.008608 0.000144 0.000342 0.000078 0.000507 0.000127 0.000309 0.000047 0.002981
Golgi 0.000125 0.000506 0.000026 0.008646 0.000327 0.000302 0.000057 0.002707 0.000206 0.000375 0.000036 0.004520
Lipid Particles 0.000060 0.000197 0.000031 0.001925 0.000099 0.000153 0.000065 0.000156 0.000076 0.000169 0.000042 0.000696
Mitochondria 0.000524 0.000538 0.000775 0.004586 0.000484 0.001069 0.001116 0.002220 0.000508 0.000878 0.000883 0.002942
Mitotic Spindle 0.000448 0.003586 0.004602 0.094022 0.001196 0.006233 0.002698 0.095755 0.000749 0.005283 0.004001 0.095226
None 0.005994 0.005697 0.008437 0.015169 0.004504 0.007235 0.005327 0.016698 0.005395 0.006683 0.007455 0.016231
Nuclear Periphery 0.000321 0.000351 0.000613 0.001559 0.000547 0.000459 0.000520 0.001384 0.000412 0.000420 0.000584 0.001438
Nuclear Periphery Foci 0.000268 0.000554 0.000036 0.003106 0.000878 0.001420 0.000090 0.000881 0.000514 0.001109 0.000053 0.001561
Nucleolus 0.000118 0.000463 0.000119 0.001349 0.000171 0.000439 0.000176 0.003618 0.000140 0.000447 0.000137 0.002925
Nucleus 0.735187 0.873668 0.850916 0.702880 0.789979 0.827037 0.943510 0.759713 0.757217 0.843775 0.880154 0.742357
Peroxisomes 0.000042 0.000060 0.000007 0.000895 0.000017 0.000053 0.000021 0.000422 0.000032 0.000056 0.000011 0.000566
Vacuole 0.001598 0.002727 0.001382 0.013908 0.002894 0.002655 0.001950 0.001442 0.002119 0.002681 0.001561 0.005249
Vacuole Periphery 0.000045 0.000301 0.000025 0.007983 0.000345 0.000322 0.000034 0.000263 0.000165 0.000314 0.000028 0.002620

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.39 0.93 -6.88 -4.90 -6.99 -2.34 -11.11 -13.09 -8.88 -3.69 -5.34 -6.34 -12.88 -8.75 -11.18
Bud Neck -3.72 -5.03 -18.22 -15.51 -17.62 -1.72 -7.20 -30.77 -29.08 -21.11 -4.33 -8.45 -35.90 -32.46 -32.09
Bud Site -3.25 -0.56 -15.56 -12.21 -15.54 -2.06 -4.66 -19.60 -17.51 -15.05 -4.24 -4.06 -25.83 -20.91 -24.52
Cell Periphery -4.22 1.87 -16.69 -15.05 -17.15 -0.40 -10.95 -14.45 -12.65 -0.42 -3.39 -6.40 -21.96 -19.17 -18.75
Cytoplasm 23.27 26.31 37.67 10.98 18.12 7.26 26.49 25.47 25.73 -3.48 21.04 34.24 47.23 27.55 20.53
Cytoplasmic Foci -2.32 4.14 -9.50 -8.15 -9.70 -0.93 -2.17 -7.81 -7.22 -5.02 -2.79 -0.18 -12.33 -10.54 -12.11
Eisosomes -4.56 -5.34 -23.57 -19.92 -22.72 -1.23 -14.58 -32.38 -29.73 -4.97 -4.90 -14.50 -39.68 -34.28 -28.00
Endoplasmic Reticulum -0.50 3.65 -4.85 -3.74 -6.42 6.44 5.16 3.37 -6.46 -4.45 3.46 6.99 -3.03 -6.50 -11.28
Endosome -1.55 0.85 -4.15 -3.65 -4.40 -2.02 0.55 -13.92 -1.90 -12.25 -2.44 1.14 -6.31 -4.18 -7.21
Golgi -1.44 0.79 -2.73 -2.05 -2.87 0.05 0.53 -3.13 -4.13 -4.75 -1.15 0.96 -4.74 -4.22 -5.54
Lipid Particles -2.37 -0.60 -7.88 -6.10 -7.84 -2.88 -3.99 -9.26 -4.33 -2.48 -3.89 -3.44 -11.23 -7.29 -9.91
Mitochondria -0.81 -3.88 -10.07 -11.12 -9.28 -1.30 -22.35 -29.66 -4.63 -13.82 -1.37 -8.59 -20.37 -7.87 -18.83
Mitotic Spindle -2.62 -5.95 -13.26 -12.03 -11.86 -3.88 -4.46 -27.45 -25.07 -24.08 -4.83 -7.38 -30.35 -27.73 -27.64
None -0.36 -9.14 -11.65 -10.82 -7.65 -4.51 -3.50 -31.80 -25.14 -28.73 -3.40 -10.19 -32.93 -27.51 -26.96
Nuclear Periphery -1.87 -15.55 -20.22 -17.92 -15.68 0.06 -7.83 -17.52 -15.73 -13.91 -1.41 -15.85 -25.61 -21.92 -19.95
Nuclear Periphery Foci -1.85 2.74 -6.10 -4.86 -6.66 -0.93 1.83 -3.94 -1.24 -8.14 -1.78 3.09 -8.61 -3.24 -11.65
Nucleolus -3.56 -2.46 -11.98 -10.99 -11.56 -2.87 -4.59 -25.49 -25.16 -23.33 -4.62 -5.15 -27.02 -26.49 -26.07
Nucleus -16.29 -21.86 5.44 16.05 17.85 -4.50 -16.45 19.13 25.46 37.45 -14.82 -26.18 18.44 30.42 40.09
Peroxisomes -1.45 0.81 -7.43 -6.92 -7.99 -3.31 -3.69 -12.83 -10.48 -7.11 -2.51 -1.59 -13.59 -12.46 -13.21
Vacuole -3.63 -5.49 -13.33 -9.90 -11.91 -3.02 -5.11 -6.00 -2.16 1.21 -5.39 -7.16 -14.95 -8.84 -9.66
Vacuole Periphery -1.89 0.83 -2.68 -2.07 -2.70 0.17 1.09 0.53 0.90 -8.69 -0.98 1.17 -2.10 -1.49 -3.50
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Specific chaperone for ribosomal protein Rpl10p; binds nascent Rpl10p during translation; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cytoplasm (74%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Sqt1

Sqt1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sqt1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available