Standard name
Human Ortholog
Description GTPase-activating protein (GAP) for yeast Rab family member Ypt6p; involved in vesicle mediated protein transport
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.07 0.18 0 0 0 0 0 0 0 0 0 0 0.06 0 0.11 0.05 0.19 0 0.07 0.07 0.09 0.08 0.1
Bud 0 0.07 0.05 0 0.08 0 0.05 0.06 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.19 0.34 0.13 0.57 0.44 0.27 0.3 0.29 0.22 0.26 0.29 0.25 0.58 0.61 0.51 0.29 0.27 0.24 0.06 0.13 0.08 0.22 0.27 0.19
Endoplasmic Reticulum 0 0.07 0.05 0 0 0 0 0.06 0.09 0.05 0 0 0.11 0.07 0.06 0.05 0 0.07 0 0 0 0 0.06 0.11
Endosome 0.53 0.29 0.08 0.05 0.29 0.17 0.09 0.13 0 0 0 0 0.22 0.2 0.29 0.37 0.44 0.27 0.42 0.38 0.39 0.31 0.28 0.23
Golgi 0 0.21 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.05 0.08 0.24 0.28 0.19 0.13 0.12 0.13 0.15
Mitochondria 0.35 0.21 0.64 0.41 0.27 0.64 0.58 0.56 0.76 0.74 0.8 0.79 0.05 0.06 0.05 0.14 0.12 0.11 0.07 0 0.13 0.11 0.08 0.08
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0
SpindlePole 0 0 0.05 0 0.08 0 0 0.07 0 0 0 0 0 0 0 0.19 0.15 0.07 0 0 0.05 0 0 0
Vac/Vac Membrane 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.05 0 0.07 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 10 4 7 2 2 3 0 5 5 4 3 1 8 22 14 24 8 14 21 7 6 24 37 56
Bud 15 4 2 2 4 3 8 12 9 9 6 11 3 13 1 4 3 2 2 3 0 3 2 8
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 3 1 0 2 6 8
Bud Site 0 0 1 0 0 0 1 1 1 2 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 1 0 0 0 0 1 0 2 1 1 3 1 4 1 3 0 1 0 0 0 0 0 1
Cytoplasm 78 20 5 35 23 26 51 60 49 53 41 51 113 232 189 64 41 18 26 13 6 63 122 113
Endoplasmic Reticulum 5 4 2 2 0 4 4 12 19 10 5 9 22 25 24 11 4 5 9 1 2 11 27 64
Endosome 220 17 3 3 15 16 16 26 7 6 4 7 44 77 107 82 68 20 199 40 32 87 129 131
Golgi 7 12 1 0 0 2 1 0 2 1 0 1 5 14 29 12 13 18 132 20 10 34 57 86
Mitochondria 146 12 25 25 14 61 99 115 169 153 113 161 9 21 17 32 18 8 35 4 11 30 34 48
Nucleus 5 1 0 0 0 0 1 0 0 0 0 0 0 2 1 0 0 0 0 0 0 1 1 0
Nuclear Periphery 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 1 0 1 0 0 1 1 2
Nucleolus 7 0 0 1 0 0 0 1 0 2 0 1 0 0 0 1 0 1 0 0 0 0 0 1
Peroxisomes 16 0 0 0 0 2 2 8 0 2 0 2 0 3 1 0 2 0 11 1 3 2 2 4
SpindlePole 9 0 2 0 4 1 6 14 5 7 0 1 0 5 6 42 23 5 12 3 4 7 10 13
Vac/Vac Membrane 11 3 1 1 1 1 5 7 1 7 1 4 3 10 16 8 13 4 10 7 2 10 19 32
Unique Cell Count 415 58 39 61 52 96 172 206 222 207 142 204 196 381 372 223 154 74 475 107 84 285 461 585
Labelled Cell Count 531 78 49 71 63 120 195 262 269 257 174 253 208 428 406 283 195 96 475 107 84 285 461 585


Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.0 7.8 5.9 5.5 6.0 5.0 4.7 4.9 4.5 4.5 4.4 4.3 7.9 7.7 7.8 7.1 8.5 9.7 7.7 7.7 8.5
Std Deviation (1e-4) 0.9 1.1 0.8 0.7 1.3 0.7 1.0 1.2 1.0 1.1 1.2 1.0 1.2 1.0 1.1 1.0 1.4 1.1 1.3 1.3 1.4
Intensity Change (Log2) – – – -0.11 0.0 -0.25 -0.35 -0.29 -0.39 -0.41 -0.42 -0.46 0.42 0.38 0.39 0.27 0.51 0.71 0.37 0.37 0.52

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 4.4 3.2 1.8 2.1 2.1 1.3 1.7 2.0 1.7 5.1 5.8 4.5 2.1 1.8 1.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 2.5 1.4 0 0 0 0 0 0 2.1 1.9 2.8 3.6 4.2 2.4
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.9
Mitochondria -2.3 -3.5 -0.1 0 0 0 0 0 0 -9.6 0 0 -6.9 -7.0 -5.9
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 2.1 1.6 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.1235 3.2517 2.9291 1.8638 2.2978 2.8446 2.1094 2.9468 2.3988 1.832 1.6282 2.2448 3.8212 4.8622 4.1459 4.1092 3.6625 3.9389
Actin 0.1892 0.0255 0.0326 0.0006 0.0057 0.0155 0.0309 0.0249 0.0054 0.0062 0.0011 0.0038 0.0691 0.0137 0.0146 0.0222 0.0063 0.0149
Bud 0.0004 0.001 0.0005 0.0006 0.0004 0.0005 0.0004 0.0021 0.0004 0.0001 0.0002 0.0002 0.0006 0.001 0.0005 0.0027 0.0003 0.0003
Bud Neck 0.0007 0.0024 0.0005 0.001 0.0014 0.009 0.0007 0.0018 0.0005 0.0004 0.0005 0.002 0.0008 0.0007 0.0009 0.0012 0.0004 0.0017
Bud Periphery 0.0003 0.0005 0.0007 0.0004 0.0007 0.0003 0.0004 0.0022 0.0003 0 0.0001 0.0001 0.0006 0.0003 0.0002 0.0014 0.001 0.0001
Bud Site 0.0013 0.0084 0.0017 0.0027 0.0042 0.0007 0.0011 0.0494 0.0044 0.0003 0.0005 0.0008 0.0029 0.0091 0.003 0.001 0.0004 0.0004
Cell Periphery 0.0001 0.0003 0.0001 0.0001 0.0003 0.0001 0.0001 0.0006 0.0003 0 0 0 0.0001 0.0003 0.0001 0.0002 0.0002 0.0001
Cytoplasm 0.1148 0.0978 0.1734 0.1009 0.007 0.1419 0.0928 0.0992 0.0705 0.1116 0.0327 0.1232 0.0459 0.1382 0.0949 0.0799 0.0055 0.1139
Cytoplasmic Foci 0.1779 0.2864 0.1863 0.2785 0.2999 0.2822 0.2792 0.337 0.3275 0.3249 0.3732 0.3492 0.2954 0.3216 0.3124 0.2701 0.3717 0.3119
Eisosomes 0.0002 0.0001 0.0004 0 0.0002 0 0.0003 0.0001 0.0004 0 0 0 0.0003 0.0002 0 0.0001 0 0
Endoplasmic Reticulum 0.0037 0.0057 0.0087 0.0034 0.0005 0.0043 0.0083 0.0019 0.0016 0.0006 0.0005 0.0027 0.0062 0.004 0.0024 0.0016 0.0011 0.0024
Endosome 0.1989 0.2581 0.3504 0.3119 0.2838 0.2258 0.319 0.2278 0.2884 0.2921 0.399 0.3313 0.3085 0.2712 0.3237 0.3296 0.3386 0.2792
Golgi 0.1471 0.1628 0.1147 0.1018 0.0666 0.1596 0.0882 0.1745 0.1401 0.119 0.1504 0.1413 0.1071 0.1568 0.1693 0.137 0.174 0.1695
Lipid Particles 0.01 0.0153 0.0142 0.0114 0.0545 0.0222 0.0152 0.0046 0.0253 0.0036 0.0157 0.0037 0.0237 0.0098 0.0069 0.0062 0.0154 0.0138
Mitochondria 0.0048 0.0052 0.0102 0.0027 0.0457 0.0142 0.0084 0.0052 0.007 0.001 0.003 0.0037 0.0099 0.0061 0.007 0.0027 0.0239 0.0113
None 0.0501 0.0572 0.0085 0.0038 0.0003 0.0192 0.0942 0.0095 0.0527 0.0044 0.0021 0.0018 0.0361 0.0181 0.0101 0.064 0.0006 0.0119
Nuclear Periphery 0.0179 0.0104 0.004 0.0074 0.001 0.0072 0.0033 0.0003 0.0004 0.0001 0.0001 0.0003 0.0081 0.0008 0.0002 0.0003 0.0003 0.0002
Nucleolus 0.0001 0.0003 0.0002 0.0023 0.0017 0.0005 0.0011 0.0001 0.0002 0 0.0001 0 0.0002 0.0001 0.0001 0.0001 0.0001 0
Nucleus 0.0532 0.0218 0.0134 0.13 0.1988 0.0143 0.0024 0.0004 0.0003 0.0001 0.0001 0.0002 0.0015 0.0002 0.0001 0.0011 0.0001 0.0002
Peroxisomes 0.0244 0.0309 0.0273 0.0219 0.0202 0.071 0.042 0.0521 0.0691 0.1337 0.0179 0.031 0.0749 0.042 0.05 0.0728 0.0559 0.0637
Punctate Nuclear 0.0021 0.0036 0.0432 0.0045 0.0025 0.0041 0.0069 0.0004 0.0013 0.0004 0.0008 0.0004 0.0035 0.001 0.0006 0.0005 0.0005 0.0011
Vacuole 0.0018 0.0053 0.0064 0.0115 0.003 0.0047 0.0037 0.0046 0.0031 0.0011 0.0012 0.0029 0.0028 0.003 0.0018 0.0041 0.0025 0.0023
Vacuole Periphery 0.001 0.0011 0.0025 0.0026 0.0017 0.0025 0.0015 0.001 0.001 0.0005 0.0008 0.0013 0.0015 0.0016 0.001 0.0014 0.0013 0.001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 12.821 19.3407 27.1087 40.6747 28.0512 25.6277 24.8064 31.0411 41.3372 34.976
Translational Efficiency 0.7351 0.5422 0.7379 0.529 0.4084 0.4714 0.5217 0.5817 0.4573 0.4201

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
306 1312 1604 1031 1542 1034 1871 130 1848 2346 3475 1161

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 798.68 930.56 948.63 968.45 912.91 863.29 929.42 967.04 894.00 900.91 938.29 968.29
Standard Deviation 110.38 140.30 112.79 123.58 125.03 118.33 103.74 139.21 129.86 135.26 108.43 125.43
Intensity Change Log 2 — 0.220482 0.248228 0.278060 — -0.080627 0.025858 0.083103 — 0.067722 0.133898 0.177362

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002004 0.001242 0.009742 0.012471 0.001783 0.002284 0.003440 0.007551 0.001819 0.001701 0.006349 0.011920
Bud Neck 0.004061 0.001200 0.002580 0.007504 0.001505 0.002358 0.008159 0.008708 0.001928 0.001710 0.005584 0.007639
Bud Site 0.020027 0.011029 0.030620 0.063535 0.014771 0.015157 0.013903 0.087445 0.015641 0.012848 0.021619 0.066212
Cell Periphery 0.000105 0.000043 0.000054 0.000115 0.000077 0.000129 0.000039 0.001020 0.000082 0.000081 0.000046 0.000216
Cytoplasm 0.027801 0.026798 0.078184 0.135625 0.049911 0.029450 0.049491 0.138964 0.046250 0.027967 0.062736 0.135999
Cytoplasmic Foci 0.431080 0.449053 0.437451 0.324146 0.453360 0.409734 0.347757 0.266613 0.449671 0.431723 0.389158 0.317704
Eisosomes 0.000085 0.000032 0.000043 0.000068 0.000058 0.000054 0.000053 0.000069 0.000063 0.000042 0.000048 0.000068
Endoplasmic Reticulum 0.002808 0.000326 0.000915 0.000705 0.001203 0.000664 0.000699 0.000791 0.001469 0.000475 0.000799 0.000715
Endosome 0.103655 0.135231 0.131178 0.089970 0.111467 0.170814 0.316398 0.111619 0.110174 0.150915 0.230903 0.092394
Golgi 0.316224 0.286257 0.107045 0.023661 0.292465 0.299272 0.052873 0.025392 0.296399 0.291994 0.077878 0.023855
Lipid Particles 0.009072 0.003046 0.010039 0.006469 0.006134 0.004549 0.014588 0.005806 0.006621 0.003708 0.012488 0.006395
Mitochondria 0.014478 0.007663 0.001497 0.003277 0.008490 0.009350 0.003380 0.001947 0.009481 0.008407 0.002511 0.003129
Mitotic Spindle 0.021158 0.043258 0.109334 0.080523 0.028972 0.020347 0.047489 0.050194 0.027678 0.033160 0.076036 0.077127
None 0.000142 0.000509 0.000045 0.000110 0.000204 0.000058 0.000058 0.000568 0.000194 0.000310 0.000052 0.000162
Nuclear Periphery 0.000070 0.000047 0.000146 0.000194 0.000101 0.000023 0.000431 0.000234 0.000096 0.000037 0.000299 0.000199
Nuclear Periphery Foci 0.000861 0.000618 0.003123 0.001166 0.001128 0.000257 0.001821 0.001188 0.001084 0.000459 0.002422 0.001168
Nucleolus 0.000216 0.000364 0.000085 0.000381 0.000180 0.000102 0.001174 0.000305 0.000186 0.000249 0.000672 0.000372
Nucleus 0.002024 0.000825 0.001299 0.004350 0.000523 0.000243 0.003553 0.013703 0.000771 0.000568 0.002513 0.005397
Peroxisomes 0.036362 0.018011 0.039555 0.131239 0.010293 0.022280 0.041145 0.118518 0.014610 0.019893 0.040411 0.129815
Vacuole 0.004459 0.009844 0.035443 0.112644 0.010273 0.008158 0.091200 0.157233 0.009311 0.009101 0.065464 0.117637
Vacuole Periphery 0.003306 0.004604 0.001622 0.001847 0.007103 0.004715 0.002348 0.002132 0.006474 0.004653 0.002013 0.001879

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.40 -7.55 -5.05 -5.88 0.30 -0.93 -2.67 -2.36 -2.00 -1.34 0.34 -8.02 -5.69 -5.80 -1.94
Bud Neck 3.93 1.63 -4.65 -14.00 -10.24 -2.29 -10.81 -5.88 -4.91 0.15 0.89 -10.11 -13.59 -13.69 -3.96
Bud Site 2.21 -2.66 -6.98 -13.05 -6.52 -0.19 0.35 -5.62 -5.57 -5.67 1.79 -4.15 -12.54 -13.70 -10.93
Cell Periphery 2.57 2.08 0.26 -2.15 -1.67 -0.68 3.41 -4.22 -3.90 -4.35 0.02 3.49 -3.60 -2.85 -4.56
Cytoplasm 0.17 -9.35 -16.87 -19.44 -9.84 4.88 -0.89 -6.10 -7.18 -5.92 5.55 -6.07 -17.25 -20.88 -14.18
Cytoplasmic Foci -1.56 0.52 13.07 21.42 18.16 5.80 16.42 13.09 10.48 6.78 3.09 12.23 24.35 22.92 15.97
Eisosomes 4.73 3.82 2.17 -5.00 -3.40 0.41 0.51 -0.72 -1.58 -1.79 2.31 1.57 0.16 -3.97 -2.76
Endoplasmic Reticulum 1.32 0.95 1.10 -2.97 1.36 1.60 1.69 1.26 -0.34 -0.21 2.51 1.54 1.80 -1.82 0.70
Endosome -3.70 -2.73 3.93 12.64 11.63 -9.26 -29.13 2.29 6.61 16.56 -9.11 -23.11 8.44 17.07 30.06
Golgi 2.04 15.50 22.19 43.04 22.13 -0.75 38.82 35.76 32.40 6.08 0.64 38.85 50.30 56.62 22.37
Lipid Particles 2.73 -0.72 1.21 -3.77 4.54 1.55 -5.69 0.75 -0.24 4.83 3.75 -6.14 0.49 -3.18 6.53
Mitochondria 2.19 4.48 4.06 3.88 -0.94 -0.49 5.34 5.81 4.62 2.07 0.84 7.61 6.27 5.32 0.36
Mitotic Spindle -4.75 -14.79 -9.38 -6.14 3.28 2.33 -5.73 -2.33 -2.86 -0.81 -1.84 -14.27 -9.30 -8.26 -0.54
None -1.14 3.10 -1.33 0.82 -2.76 4.47 3.77 -2.56 -3.41 -3.30 -0.64 4.69 -1.37 0.12 -3.48
Nuclear Periphery 0.82 -2.60 -6.71 -10.67 -5.65 2.20 -3.24 -4.37 -6.30 0.69 1.95 -3.67 -7.54 -12.91 -0.58
Nuclear Periphery Foci 0.31 -3.84 -3.30 -3.59 1.96 3.63 -2.49 -1.74 -4.72 0.68 2.06 -4.34 -3.44 -5.31 1.41
Nucleolus -0.60 1.49 -2.52 -0.94 -3.66 1.16 -3.66 -1.86 -2.73 3.00 -0.50 -3.37 -3.10 -1.90 0.98
Nucleus 1.06 0.34 -2.98 -5.30 -4.72 3.29 -5.33 -4.01 -4.05 -3.47 0.74 -4.90 -6.73 -6.90 -5.16
Peroxisomes 4.19 -0.52 -9.39 -14.94 -10.62 -5.78 -13.97 -5.12 -4.23 -2.92 -3.32 -13.90 -16.58 -15.41 -11.22
Vacuole -4.39 -15.90 -24.70 -24.05 -18.90 1.89 -22.58 -8.91 -9.00 -5.02 0.26 -26.05 -25.75 -25.80 -16.13
Vacuole Periphery -1.75 2.66 2.76 6.67 0.72 2.82 8.03 7.61 4.08 1.29 3.02 8.92 8.88 7.33 1.87
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description GTPase-activating protein (GAP) for yeast Rab family member Ypt6p; involved in vesicle mediated protein transport
Localization
Cell Percentages cytoplasm (34%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-3

Gyp6

Gyp6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gyp6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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