| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Inositol-3-phosphate synthase; involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 0 | – | – | 0 | 2 | 0 | 0 | – | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| Bud | 1 | – | – | 1 | 1 | 0 | 0 | – | 3 | 0 | 2 | 3 | – | 0 | 0 | 0 | 1 | 0 | 2 | 3 | 0 | 1 | 0 | 1 |
| Bud Neck | 0 | – | – | 0 | 1 | 2 | 2 | – | 0 | 0 | 5 | 4 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Bud Site | 0 | – | – | 0 | 0 | 0 | 0 | – | 0 | 0 | 1 | 1 | – | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
| Cell Periphery | 0 | – | – | 2 | 3 | 3 | 5 | – | 0 | 0 | 0 | 1 | – | 0 | 3 | 13 | 7 | 9 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cytoplasm | 110 | – | – | 110 | 206 | 194 | 255 | – | 67 | 91 | 92 | 139 | – | 18 | 104 | 145 | 179 | 212 | 105 | 54 | 11 | 6 | 27 | 49 |
| Endoplasmic Reticulum | 0 | – | – | 1 | 0 | 0 | 3 | – | 1 | 0 | 0 | 2 | – | 0 | 0 | 6 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Endosome | 0 | – | – | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Golgi | 0 | – | – | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | – | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Mitochondria | 5 | – | – | 2 | 1 | 11 | 27 | – | 43 | 23 | 70 | 78 | – | 0 | 1 | 3 | 0 | 1 | 2 | 2 | 0 | 0 | 0 | 0 |
| Nucleus | 0 | – | – | 1 | 1 | 2 | 1 | – | 1 | 1 | 2 | 1 | – | 0 | 2 | 2 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
| Nuclear Periphery | 0 | – | – | 0 | 0 | 1 | 0 | – | 0 | 0 | 0 | 1 | – | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Nucleolus | 0 | – | – | 0 | 0 | 0 | 0 | – | 1 | 1 | 0 | 0 | – | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Peroxisomes | 0 | – | – | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| SpindlePole | 0 | – | – | 0 | 0 | 0 | 0 | – | 0 | 0 | 4 | 0 | – | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| Vac/Vac Membrane | 0 | – | – | 3 | 7 | 9 | 13 | – | 4 | 5 | 1 | 10 | – | 0 | 1 | 21 | 24 | 33 | 1 | 0 | 0 | 0 | 1 | 3 |
| Unique Cell Count | 110 | 113 | 214 | 208 | 287 | 98 | 110 | 146 | 195 | 18 | 109 | 163 | 199 | 238 | 120 | 66 | 13 | 10 | 34 | 57 | ||||
| Labelled Cell Count | 116 | 120 | 222 | 222 | 306 | 120 | 121 | 177 | 240 | 18 | 113 | 192 | 216 | 259 | 120 | 66 | 13 | 10 | 34 | 57 | ||||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 6.3 | – | – | 6.6 | 7.0 | 5.7 | 6.3 | – | 4.8 | 4.7 | 4.4 | 4.6 | – | 6.5 | 7.8 | 22.5 | 19.7 | 20.0 | – | – | 8.0 |
| Std Deviation (1e-4) | 4.9 | – | – | 5.8 | 3.4 | 2.8 | 4.4 | – | 4.7 | 2.6 | 2.8 | 3.5 | – | 1.4 | 9.1 | 18.9 | 15.1 | 15.4 | – | – | 4.8 |
| Intensity Change (Log2) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | 0.017 | 0.0002 | 0.023 | 0.0697 | 0.0002 | 0.0002 | – | – | – | – | – | – | 0.06 | 0.0272 | 0.0248 | 0 | 0.0255 | 0.0004 |
| Bud | 0.0004 | 0.0001 | 0.0012 | 0.0032 | 0 | 0.0001 | – | – | – | – | – | – | 0.0048 | 0.0006 | 0.0016 | 0 | 0.0147 | 0.0007 |
| Bud Neck | 0.0004 | 0.0001 | 0.0006 | 0.0009 | 0.0001 | 0.0007 | – | – | – | – | – | – | 0.002 | 0.0002 | 0.0007 | 0.0002 | 0.0017 | 0.0004 |
| Bud Periphery | 0.0006 | 0.0001 | 0.0032 | 0.002 | 0 | 0.0001 | – | – | – | – | – | – | 0.0027 | 0.0005 | 0.001 | 0 | 0.0085 | 0.0002 |
| Bud Site | 0.0011 | 0.0007 | 0.0041 | 0.0059 | 0 | 0 | – | – | – | – | – | – | 0.026 | 0.0012 | 0.003 | 0 | 0.146 | 0.0007 |
| Cell Periphery | 0.0002 | 0.0001 | 0.0013 | 0.0005 | 0 | 0 | – | – | – | – | – | – | 0.0011 | 0.0002 | 0.0002 | 0 | 0.0007 | 0.0001 |
| Cytoplasm | 0.3902 | 0.7544 | 0.5383 | 0.3741 | 0.4201 | 0.7113 | – | – | – | – | – | – | 0.4273 | 0.7293 | 0.7962 | 0.9947 | 0.3741 | 0.8619 |
| Cytoplasmic Foci | 0.0113 | 0.0036 | 0.0179 | 0.0205 | 0.0091 | 0.007 | – | – | – | – | – | – | 0.0366 | 0.0045 | 0.0243 | 0.0003 | 0.024 | 0.0163 |
| Eisosomes | 0.0002 | 0.0001 | 0.0017 | 0.0014 | 0 | 0 | – | – | – | – | – | – | 0.0006 | 0.0001 | 0 | 0 | 0.0001 | 0 |
| Endoplasmic Reticulum | 0.0076 | 0.0028 | 0.0052 | 0.0045 | 0.0128 | 0.0043 | – | – | – | – | – | – | 0.0198 | 0.003 | 0.0031 | 0.0006 | 0.0037 | 0.0021 |
| Endosome | 0.0557 | 0.0019 | 0.0154 | 0.0313 | 0.0155 | 0.0069 | – | – | – | – | – | – | 0.0479 | 0.0021 | 0.0064 | 0.0002 | 0.0757 | 0.001 |
| Golgi | 0.0157 | 0.0001 | 0.0103 | 0.0403 | 0.0003 | 0.0001 | – | – | – | – | – | – | 0.0141 | 0.0008 | 0.0053 | 0 | 0.0529 | 0.0001 |
| Lipid Particles | 0.011 | 0.0002 | 0.0034 | 0.0047 | 0.0001 | 0.0001 | – | – | – | – | – | – | 0.0114 | 0.0005 | 0.0019 | 0 | 0.021 | 0.0003 |
| Mitochondria | 0.0147 | 0.0002 | 0.0206 | 0.0092 | 0.0002 | 0.0004 | – | – | – | – | – | – | 0.0178 | 0.0002 | 0.0008 | 0 | 0.0143 | 0.0002 |
| None | 0.3971 | 0.2318 | 0.3419 | 0.3788 | 0.5354 | 0.2061 | – | – | – | – | – | – | 0.1317 | 0.2247 | 0.1138 | 0.0014 | 0.2164 | 0.1078 |
| Nuclear Periphery | 0.029 | 0.0008 | 0.0022 | 0.0048 | 0.0022 | 0.0343 | – | – | – | – | – | – | 0.0803 | 0.0009 | 0.0009 | 0.0004 | 0.003 | 0.001 |
| Nucleolus | 0.0005 | 0.0001 | 0.0002 | 0.0081 | 0 | 0 | – | – | – | – | – | – | 0.0036 | 0 | 0 | 0 | 0.0004 | 0.0002 |
| Nucleus | 0.0357 | 0.0014 | 0.0029 | 0.0063 | 0.0008 | 0.0173 | – | – | – | – | – | – | 0.0439 | 0.0018 | 0.0018 | 0.0015 | 0.0024 | 0.0035 |
| Peroxisomes | 0.0016 | 0 | 0.0023 | 0.003 | 0.0001 | 0 | – | – | – | – | – | – | 0.0059 | 0.0006 | 0.0129 | 0 | 0.0036 | 0 |
| Punctate Nuclear | 0.0024 | 0.0005 | 0.0009 | 0.0281 | 0.0006 | 0.0007 | – | – | – | – | – | – | 0.0487 | 0.0006 | 0.0004 | 0 | 0.0019 | 0.0019 |
| Vacuole | 0.0045 | 0.0009 | 0.0023 | 0.0018 | 0.0018 | 0.005 | – | – | – | – | – | – | 0.0082 | 0.001 | 0.0009 | 0.0006 | 0.0069 | 0.0008 |
| Vacuole Periphery | 0.0033 | 0.0001 | 0.0009 | 0.0009 | 0.0005 | 0.0052 | – | – | – | – | – | – | 0.0055 | 0.0001 | 0.0002 | 0 | 0.0023 | 0.0002 |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 8.2652 | 5.5414 | 3.6551 | 3.4653 | 4.9116 | 3.4419 | 6.6924 | 5.2522 | 4.2769 | 3.6252 |
| Translational Efficiency | – | – | – | – | – | – | – | – | – | – |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | ✘ |
| Gene Expression | ✘ |
| Translational Efficiency | – |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 2067 | 270 | 181 | 679 | 1832 | 672 | 175 | 272 | 3899 | 942 | 356 | 951 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 715.31 | 766.10 | 927.69 | 785.57 | 683.91 | 729.26 | 890.21 | 858.92 | 700.56 | 739.82 | 909.27 | 806.55 |
| Standard Deviation | 178.05 | 193.98 | 121.43 | 209.39 | 202.39 | 461.86 | 88.38 | 115.20 | 190.52 | 404.03 | 108.11 | 190.26 |
| Intensity Change Log 2 | — | 0.098964 | 0.375074 | 0.135171 | — | 0.092627 | 0.380339 | 0.328717 | — | 0.095870 | 0.377650 | 0.233017 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000146 | 0.000858 | 0.001208 | 0.000190 | 0.000105 | 0.000148 | 0.000259 | 0.000262 | 0.000126 | 0.000351 | 0.000742 | 0.000211 |
| Bud Neck | 0.021087 | 0.010739 | 0.004137 | 0.004695 | 0.009643 | 0.027299 | 0.001528 | 0.002952 | 0.015710 | 0.022552 | 0.002854 | 0.004197 |
| Bud Site | 0.025790 | 0.019566 | 0.008398 | 0.015648 | 0.004875 | 0.009027 | 0.001793 | 0.026694 | 0.015963 | 0.012048 | 0.005151 | 0.018807 |
| Cell Periphery | 0.000331 | 0.000208 | 0.000376 | 0.000255 | 0.000322 | 0.000272 | 0.000225 | 0.000122 | 0.000327 | 0.000254 | 0.000302 | 0.000217 |
| Cytoplasm | 0.648264* | 0.536347* | 0.155139* | 0.488196* | 0.608396* | 0.390347* | 0.385018* | 0.513346* | 0.629532* | 0.432194* | 0.268142* | 0.495389* |
| Cytoplasmic Foci | 0.092771 | 0.217829* | 0.015968 | 0.040056 | 0.175872 | 0.190542* | 0.033081 | 0.026252 | 0.131817 | 0.198363* | 0.024381 | 0.036107 |
| Eisosomes | 0.000103 | 0.000091 | 0.000126 | 0.000086 | 0.000128 | 0.000150 | 0.000110 | 0.000048 | 0.000115 | 0.000133 | 0.000118 | 0.000076 |
| Endoplasmic Reticulum | 0.000772 | 0.001206 | 0.016710 | 0.001171 | 0.000681 | 0.001172 | 0.003967 | 0.001764 | 0.000729 | 0.001182 | 0.010446 | 0.001341 |
| Endosome | 0.003582 | 0.025897 | 0.005711 | 0.007230 | 0.006137 | 0.037887 | 0.006600 | 0.015526 | 0.004782 | 0.034451 | 0.006148 | 0.009603 |
| Golgi | 0.001695 | 0.003372 | 0.000541 | 0.002102 | 0.001932 | 0.005030 | 0.000101 | 0.000491 | 0.001806 | 0.004555 | 0.000324 | 0.001642 |
| Lipid Particles | 0.002398 | 0.004087 | 0.004987 | 0.001441 | 0.004969 | 0.012722 | 0.004381 | 0.001325 | 0.003606 | 0.010247 | 0.004689 | 0.001408 |
| Mitochondria | 0.002812 | 0.001266 | 0.000762 | 0.001183 | 0.002598 | 0.011514 | 0.000224 | 0.001392 | 0.002711 | 0.008577 | 0.000497 | 0.001243 |
| Mitotic Spindle | 0.001706 | 0.002586 | 0.000973 | 0.015667 | 0.001831 | 0.006279 | 0.000388 | 0.009296 | 0.001765 | 0.005221 | 0.000685 | 0.013844 |
| None | 0.029051 | 0.009184 | 0.002518 | 0.009487 | 0.007395 | 0.007715 | 0.006000 | 0.007640 | 0.018876 | 0.008136 | 0.004230 | 0.008958 |
| Nuclear Periphery | 0.000191 | 0.000322 | 0.002452 | 0.000970 | 0.000300 | 0.001121 | 0.001880 | 0.001246 | 0.000242 | 0.000892 | 0.002171 | 0.001049 |
| Nuclear Periphery Foci | 0.000862 | 0.002429 | 0.003522 | 0.001371 | 0.000368 | 0.000897 | 0.002881 | 0.000952 | 0.000630 | 0.001336 | 0.003207 | 0.001252 |
| Nucleolus | 0.001912 | 0.003983 | 0.001296 | 0.001030 | 0.000727 | 0.004500 | 0.000663 | 0.000587 | 0.001355 | 0.004352 | 0.000985 | 0.000903 |
| Nucleus | 0.138439* | 0.073046 | 0.677492* | 0.300405* | 0.137897* | 0.175898* | 0.419503* | 0.218253* | 0.138184* | 0.146418* | 0.550671* | 0.276908* |
| Peroxisomes | 0.001270 | 0.006477 | 0.000700 | 0.000613 | 0.001573 | 0.009691 | 0.000426 | 0.000341 | 0.001412 | 0.008770 | 0.000565 | 0.000535 |
| Vacuole | 0.025666 | 0.078072 | 0.096389 | 0.107057 | 0.033329 | 0.103694 | 0.130743 | 0.170442 | 0.029267 | 0.096350 | 0.113277 | 0.125186 |
| Vacuole Periphery | 0.001152 | 0.002436 | 0.000595 | 0.001148 | 0.000924 | 0.004094 | 0.000229 | 0.001070 | 0.001045 | 0.003619 | 0.000415 | 0.001126 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | -1.83 | -10.49 | -1.00 | 1.70 | 10.46 | -1.51 | -5.92 | -4.78 | -3.50 | 1.26 | -1.96 | -10.68 | -2.99 | 1.12 | 9.61 |
| Bud Neck | 5.24 | 11.26 | 12.68 | 3.30 | 1.20 | -5.77 | 8.65 | 5.29 | 7.88 | -4.79 | -2.88 | 14.15 | 12.68 | 8.29 | -0.93 |
| Bud Site | 2.13 | 5.33 | 4.25 | 1.78 | -1.16 | -2.26 | 4.38 | -2.44 | -1.36 | -3.15 | 2.45 | 6.17 | 1.21 | -0.53 | -3.07 |
| Cell Periphery | 3.70 | -2.19 | 5.29 | 0.46 | 5.72 | 0.62 | 1.08 | 2.59 | 3.40 | 6.87 | 1.41 | 0.16 | 3.67 | 2.26 | 6.59 |
| Cytoplasm | 6.49 | 41.52 | 17.31 | 4.59 | -19.66 | 17.85 | 14.23 | 13.46 | 1.74 | -1.12 | 19.69 | 31.69 | 21.01 | 1.20 | -12.40 |
| Cytoplasmic Foci | -9.90 | 19.57 | 17.02 | 14.95 | -5.66 | -1.68 | 26.47 | 29.93 | 22.18 | 2.71 | -9.86 | 31.68 | 33.16 | 26.57 | -2.35 |
| Eisosomes | 0.61 | -3.98 | 3.00 | 0.55 | 5.96 | -1.75 | -0.57 | 5.38 | 7.10 | 5.22 | -1.88 | -3.31 | 5.83 | 5.93 | 7.76 |
| Endoplasmic Reticulum | -2.40 | -13.06 | -2.42 | -0.75 | 12.47 | -2.27 | -9.40 | -6.41 | -5.45 | 3.20 | -3.27 | -13.51 | -5.28 | -3.35 | 11.91 |
| Endosome | -6.01 | -4.10 | -1.63 | 5.43 | 1.28 | -9.22 | -1.44 | -0.07 | 7.11 | 0.32 | -11.08 | -4.03 | -0.65 | 10.10 | 1.26 |
| Golgi | -2.23 | 5.25 | 0.83 | 2.31 | -1.38 | -2.86 | 6.32 | 5.62 | 4.59 | -1.43 | -3.47 | 8.34 | 2.03 | 4.14 | -1.66 |
| Lipid Particles | -2.33 | -5.28 | 3.64 | 3.81 | 7.33 | -4.93 | 0.14 | 6.54 | 7.51 | 6.67 | -5.96 | -3.59 | 7.53 | 8.12 | 9.97 |
| Mitochondria | 4.22 | 6.57 | 5.14 | 1.09 | 0.20 | -4.03 | 3.75 | 2.76 | 5.07 | -2.13 | -3.75 | 6.43 | 4.92 | 5.08 | -1.10 |
| Mitotic Spindle | -0.75 | 0.94 | -3.15 | -2.64 | -3.32 | -2.01 | 2.12 | -3.06 | -1.74 | -3.44 | -2.18 | 2.22 | -4.17 | -2.42 | -4.57 |
| None | 6.77 | 17.07 | 10.17 | 0.56 | -3.62 | -0.22 | 1.57 | 1.70 | 1.35 | -0.47 | 6.52 | 12.67 | 8.52 | 0.80 | -2.65 |
| Nuclear Periphery | -2.50 | -14.65 | -6.48 | -5.59 | 6.85 | -1.99 | -12.86 | -11.19 | -2.57 | -0.17 | -2.23 | -18.95 | -9.82 | -2.29 | 5.91 |
| Nuclear Periphery Foci | -2.98 | -6.39 | -0.71 | 2.36 | 5.80 | -1.82 | -6.92 | -5.48 | -1.39 | 4.26 | -2.48 | -8.98 | -1.89 | 0.43 | 6.67 |
| Nucleolus | -1.39 | 2.83 | 3.62 | 2.20 | 1.53 | -4.10 | 1.32 | 0.58 | 4.16 | -0.15 | -3.85 | 3.24 | 2.89 | 4.57 | 0.97 |
| Nucleus | 6.85 | -25.34 | -14.34 | -16.09 | 16.26 | -4.25 | -13.25 | -7.10 | -4.09 | 6.64 | -1.19 | -25.09 | -16.02 | -12.20 | 14.61 |
| Peroxisomes | -4.58 | 4.38 | 6.01 | 5.36 | 2.30 | -5.20 | 10.06 | 12.35 | 6.07 | 3.43 | -6.32 | 9.55 | 10.56 | 7.23 | 2.62 |
| Vacuole | -8.40 | -8.95 | -17.91 | -9.67 | -1.97 | -11.84 | -10.22 | -16.12 | -11.64 | -5.17 | -14.75 | -13.54 | -23.25 | -13.52 | -3.69 |
| Vacuole Periphery | -1.72 | 3.68 | 1.71 | 2.27 | -0.80 | -5.00 | 3.21 | 1.82 | 5.98 | -1.15 | -5.29 | 4.91 | 2.03 | 6.01 | -1.47 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Inositol-3-phosphate synthase; involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element |
| Localization | |
| Cell Percentages | cytoplasm (80%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | cytoplasm-9 |
Ino1
Ino1
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Ino1-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
