Standard name
Human Ortholog
Description Inositol-3-phosphate synthase; involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0.1 0 0
Bud Neck 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 – – – – – –
Cell Periphery 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0.08 0 0 0 0 0 0 0 0
Cytoplasm 1.0 – – 0.97 0.96 0.93 0.89 – 0.68 0.83 0.63 0.71 – 1.0 0.95 0.89 0.9 0.89 0.88 0.82 0.89 0.68 0.8 0.88
Endoplasmic Reticulum 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 – – 0 0 0.05 0.09 – 0.44 0.21 0.48 0.4 – 0 0 0 0 0 0 0 0 0.08 0 0
Nucleus 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0
Nuclear Periphery 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 – – 0 0 0 0.05 – 0 0.05 0 0.05 – 0 0 0.13 0.12 0.14 0 0 0.05 0 0.05 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 – – 0 2 0 0 – 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 1
Bud 1 – – 1 1 0 0 – 3 0 2 3 – 0 0 0 1 0 2 3 0 1 0 1
Bud Neck 0 – – 0 1 2 2 – 0 0 5 4 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 – – 0 0 0 0 – 0 0 1 1 – 0 0 0 0 0 – – – – – –
Cell Periphery 0 – – 2 3 3 5 – 0 0 0 1 – 0 3 13 7 9 0 0 0 0 0 0
Cytoplasm 110 – – 110 206 194 255 – 67 91 92 139 – 18 104 145 179 212 105 54 11 6 27 49
Endoplasmic Reticulum 0 – – 1 0 0 3 – 1 0 0 2 – 0 0 6 2 2 0 0 0 0 0 0
Endosome 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 1 1 0 0 0 0 0
Golgi 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 2 1 0 0 0 0 0 0 0
Mitochondria 5 – – 2 1 11 27 – 43 23 70 78 – 0 1 3 0 1 2 2 0 0 0 0
Nucleus 0 – – 1 1 2 1 – 1 1 2 1 – 0 2 2 1 1 0 1 0 0 1 0
Nuclear Periphery 0 – – 0 0 1 0 – 0 0 0 1 – 0 1 0 0 0 0 0 0 0 0 0
Nucleolus 0 – – 0 0 0 0 – 1 1 0 0 – 0 0 0 1 0 0 0 0 0 0 0
Peroxisomes 0 – – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 – – 0 0 0 0 – 0 0 4 0 – 0 1 0 0 0 0 1 0 0 0 0
Vac/Vac Membrane 0 – – 3 7 9 13 – 4 5 1 10 – 0 1 21 24 33 1 0 0 0 1 3
Unique Cell Count 110 113 214 208 287 98 110 146 195 18 109 163 199 238 120 66 13 10 34 57
Labelled Cell Count 116 120 222 222 306 120 121 177 240 18 113 192 216 259 120 66 13 10 34 57


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.3 – – 6.6 7.0 5.7 6.3 – 4.8 4.7 4.4 4.6 – 6.5 7.8 22.5 19.7 20.0 – – 8.0
Std Deviation (1e-4) 4.9 – – 5.8 3.4 2.8 4.4 – 4.7 2.6 2.8 3.5 – 1.4 9.1 18.9 15.1 15.4 – – 4.8
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –

RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700010203040HU120HU160010203040rpd3Δ_1rpd3Δ_2rpd3Δ_3010203040WT1AF180010203040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.017 0.0002 0.023 0.0697 0.0002 0.0002 – – – – – – 0.06 0.0272 0.0248 0 0.0255 0.0004
Bud 0.0004 0.0001 0.0012 0.0032 0 0.0001 – – – – – – 0.0048 0.0006 0.0016 0 0.0147 0.0007
Bud Neck 0.0004 0.0001 0.0006 0.0009 0.0001 0.0007 – – – – – – 0.002 0.0002 0.0007 0.0002 0.0017 0.0004
Bud Periphery 0.0006 0.0001 0.0032 0.002 0 0.0001 – – – – – – 0.0027 0.0005 0.001 0 0.0085 0.0002
Bud Site 0.0011 0.0007 0.0041 0.0059 0 0 – – – – – – 0.026 0.0012 0.003 0 0.146 0.0007
Cell Periphery 0.0002 0.0001 0.0013 0.0005 0 0 – – – – – – 0.0011 0.0002 0.0002 0 0.0007 0.0001
Cytoplasm 0.3902 0.7544 0.5383 0.3741 0.4201 0.7113 – – – – – – 0.4273 0.7293 0.7962 0.9947 0.3741 0.8619
Cytoplasmic Foci 0.0113 0.0036 0.0179 0.0205 0.0091 0.007 – – – – – – 0.0366 0.0045 0.0243 0.0003 0.024 0.0163
Eisosomes 0.0002 0.0001 0.0017 0.0014 0 0 – – – – – – 0.0006 0.0001 0 0 0.0001 0
Endoplasmic Reticulum 0.0076 0.0028 0.0052 0.0045 0.0128 0.0043 – – – – – – 0.0198 0.003 0.0031 0.0006 0.0037 0.0021
Endosome 0.0557 0.0019 0.0154 0.0313 0.0155 0.0069 – – – – – – 0.0479 0.0021 0.0064 0.0002 0.0757 0.001
Golgi 0.0157 0.0001 0.0103 0.0403 0.0003 0.0001 – – – – – – 0.0141 0.0008 0.0053 0 0.0529 0.0001
Lipid Particles 0.011 0.0002 0.0034 0.0047 0.0001 0.0001 – – – – – – 0.0114 0.0005 0.0019 0 0.021 0.0003
Mitochondria 0.0147 0.0002 0.0206 0.0092 0.0002 0.0004 – – – – – – 0.0178 0.0002 0.0008 0 0.0143 0.0002
None 0.3971 0.2318 0.3419 0.3788 0.5354 0.2061 – – – – – – 0.1317 0.2247 0.1138 0.0014 0.2164 0.1078
Nuclear Periphery 0.029 0.0008 0.0022 0.0048 0.0022 0.0343 – – – – – – 0.0803 0.0009 0.0009 0.0004 0.003 0.001
Nucleolus 0.0005 0.0001 0.0002 0.0081 0 0 – – – – – – 0.0036 0 0 0 0.0004 0.0002
Nucleus 0.0357 0.0014 0.0029 0.0063 0.0008 0.0173 – – – – – – 0.0439 0.0018 0.0018 0.0015 0.0024 0.0035
Peroxisomes 0.0016 0 0.0023 0.003 0.0001 0 – – – – – – 0.0059 0.0006 0.0129 0 0.0036 0
Punctate Nuclear 0.0024 0.0005 0.0009 0.0281 0.0006 0.0007 – – – – – – 0.0487 0.0006 0.0004 0 0.0019 0.0019
Vacuole 0.0045 0.0009 0.0023 0.0018 0.0018 0.005 – – – – – – 0.0082 0.001 0.0009 0.0006 0.0069 0.0008
Vacuole Periphery 0.0033 0.0001 0.0009 0.0009 0.0005 0.0052 – – – – – – 0.0055 0.0001 0.0002 0 0.0023 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 8.2652 5.5414 3.6551 3.4653 4.9116 3.4419 6.6924 5.2522 4.2769 3.6252
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2067 270 181 679 1832 672 175 272 3899 942 356 951

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 715.31 766.10 927.69 785.57 683.91 729.26 890.21 858.92 700.56 739.82 909.27 806.55
Standard Deviation 178.05 193.98 121.43 209.39 202.39 461.86 88.38 115.20 190.52 404.03 108.11 190.26
Intensity Change Log 2 — 0.098964 0.375074 0.135171 — 0.092627 0.380339 0.328717 — 0.095870 0.377650 0.233017

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000146 0.000858 0.001208 0.000190 0.000105 0.000148 0.000259 0.000262 0.000126 0.000351 0.000742 0.000211
Bud Neck 0.021087 0.010739 0.004137 0.004695 0.009643 0.027299 0.001528 0.002952 0.015710 0.022552 0.002854 0.004197
Bud Site 0.025790 0.019566 0.008398 0.015648 0.004875 0.009027 0.001793 0.026694 0.015963 0.012048 0.005151 0.018807
Cell Periphery 0.000331 0.000208 0.000376 0.000255 0.000322 0.000272 0.000225 0.000122 0.000327 0.000254 0.000302 0.000217
Cytoplasm 0.648264 0.536347 0.155139 0.488196 0.608396 0.390347 0.385018 0.513346 0.629532 0.432194 0.268142 0.495389
Cytoplasmic Foci 0.092771 0.217829 0.015968 0.040056 0.175872 0.190542 0.033081 0.026252 0.131817 0.198363 0.024381 0.036107
Eisosomes 0.000103 0.000091 0.000126 0.000086 0.000128 0.000150 0.000110 0.000048 0.000115 0.000133 0.000118 0.000076
Endoplasmic Reticulum 0.000772 0.001206 0.016710 0.001171 0.000681 0.001172 0.003967 0.001764 0.000729 0.001182 0.010446 0.001341
Endosome 0.003582 0.025897 0.005711 0.007230 0.006137 0.037887 0.006600 0.015526 0.004782 0.034451 0.006148 0.009603
Golgi 0.001695 0.003372 0.000541 0.002102 0.001932 0.005030 0.000101 0.000491 0.001806 0.004555 0.000324 0.001642
Lipid Particles 0.002398 0.004087 0.004987 0.001441 0.004969 0.012722 0.004381 0.001325 0.003606 0.010247 0.004689 0.001408
Mitochondria 0.002812 0.001266 0.000762 0.001183 0.002598 0.011514 0.000224 0.001392 0.002711 0.008577 0.000497 0.001243
Mitotic Spindle 0.001706 0.002586 0.000973 0.015667 0.001831 0.006279 0.000388 0.009296 0.001765 0.005221 0.000685 0.013844
None 0.029051 0.009184 0.002518 0.009487 0.007395 0.007715 0.006000 0.007640 0.018876 0.008136 0.004230 0.008958
Nuclear Periphery 0.000191 0.000322 0.002452 0.000970 0.000300 0.001121 0.001880 0.001246 0.000242 0.000892 0.002171 0.001049
Nuclear Periphery Foci 0.000862 0.002429 0.003522 0.001371 0.000368 0.000897 0.002881 0.000952 0.000630 0.001336 0.003207 0.001252
Nucleolus 0.001912 0.003983 0.001296 0.001030 0.000727 0.004500 0.000663 0.000587 0.001355 0.004352 0.000985 0.000903
Nucleus 0.138439 0.073046 0.677492 0.300405 0.137897 0.175898 0.419503 0.218253 0.138184 0.146418 0.550671 0.276908
Peroxisomes 0.001270 0.006477 0.000700 0.000613 0.001573 0.009691 0.000426 0.000341 0.001412 0.008770 0.000565 0.000535
Vacuole 0.025666 0.078072 0.096389 0.107057 0.033329 0.103694 0.130743 0.170442 0.029267 0.096350 0.113277 0.125186
Vacuole Periphery 0.001152 0.002436 0.000595 0.001148 0.000924 0.004094 0.000229 0.001070 0.001045 0.003619 0.000415 0.001126

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.83 -10.49 -1.00 1.70 10.46 -1.51 -5.92 -4.78 -3.50 1.26 -1.96 -10.68 -2.99 1.12 9.61
Bud Neck 5.24 11.26 12.68 3.30 1.20 -5.77 8.65 5.29 7.88 -4.79 -2.88 14.15 12.68 8.29 -0.93
Bud Site 2.13 5.33 4.25 1.78 -1.16 -2.26 4.38 -2.44 -1.36 -3.15 2.45 6.17 1.21 -0.53 -3.07
Cell Periphery 3.70 -2.19 5.29 0.46 5.72 0.62 1.08 2.59 3.40 6.87 1.41 0.16 3.67 2.26 6.59
Cytoplasm 6.49 41.52 17.31 4.59 -19.66 17.85 14.23 13.46 1.74 -1.12 19.69 31.69 21.01 1.20 -12.40
Cytoplasmic Foci -9.90 19.57 17.02 14.95 -5.66 -1.68 26.47 29.93 22.18 2.71 -9.86 31.68 33.16 26.57 -2.35
Eisosomes 0.61 -3.98 3.00 0.55 5.96 -1.75 -0.57 5.38 7.10 5.22 -1.88 -3.31 5.83 5.93 7.76
Endoplasmic Reticulum -2.40 -13.06 -2.42 -0.75 12.47 -2.27 -9.40 -6.41 -5.45 3.20 -3.27 -13.51 -5.28 -3.35 11.91
Endosome -6.01 -4.10 -1.63 5.43 1.28 -9.22 -1.44 -0.07 7.11 0.32 -11.08 -4.03 -0.65 10.10 1.26
Golgi -2.23 5.25 0.83 2.31 -1.38 -2.86 6.32 5.62 4.59 -1.43 -3.47 8.34 2.03 4.14 -1.66
Lipid Particles -2.33 -5.28 3.64 3.81 7.33 -4.93 0.14 6.54 7.51 6.67 -5.96 -3.59 7.53 8.12 9.97
Mitochondria 4.22 6.57 5.14 1.09 0.20 -4.03 3.75 2.76 5.07 -2.13 -3.75 6.43 4.92 5.08 -1.10
Mitotic Spindle -0.75 0.94 -3.15 -2.64 -3.32 -2.01 2.12 -3.06 -1.74 -3.44 -2.18 2.22 -4.17 -2.42 -4.57
None 6.77 17.07 10.17 0.56 -3.62 -0.22 1.57 1.70 1.35 -0.47 6.52 12.67 8.52 0.80 -2.65
Nuclear Periphery -2.50 -14.65 -6.48 -5.59 6.85 -1.99 -12.86 -11.19 -2.57 -0.17 -2.23 -18.95 -9.82 -2.29 5.91
Nuclear Periphery Foci -2.98 -6.39 -0.71 2.36 5.80 -1.82 -6.92 -5.48 -1.39 4.26 -2.48 -8.98 -1.89 0.43 6.67
Nucleolus -1.39 2.83 3.62 2.20 1.53 -4.10 1.32 0.58 4.16 -0.15 -3.85 3.24 2.89 4.57 0.97
Nucleus 6.85 -25.34 -14.34 -16.09 16.26 -4.25 -13.25 -7.10 -4.09 6.64 -1.19 -25.09 -16.02 -12.20 14.61
Peroxisomes -4.58 4.38 6.01 5.36 2.30 -5.20 10.06 12.35 6.07 3.43 -6.32 9.55 10.56 7.23 2.62
Vacuole -8.40 -8.95 -17.91 -9.67 -1.97 -11.84 -10.22 -16.12 -11.64 -5.17 -14.75 -13.54 -23.25 -13.52 -3.69
Vacuole Periphery -1.72 3.68 1.71 2.27 -0.80 -5.00 3.21 1.82 5.98 -1.15 -5.29 4.91 2.03 6.01 -1.47
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Inositol-3-phosphate synthase; involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
Localization
Cell Percentages cytoplasm (80%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ino1

Ino1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ino1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available