Standard name
Human Ortholog
Description Protein that associates with mitochondrial ribosome; detected in highly purified mitochondria in high-throughput studies; predicted to be involved in ribosome biogenesis
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0.06 0 0 0.06 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0.05 0.07
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0.09 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.05 0.12 0.68 0.7 0.69 0.63 0.6 0.57 0.52 0.5 0.49 0.45 0.67 0.69 0.74 – – – 0 0 0.53 0.4 0.3 0.31
Endoplasmic Reticulum 0 0.06 0.05 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0.12 0 0 0 0.05 0 0 0 0 0 0 0 0.06 0.07 0 – – – 0.22 0.13 0.05 0.09 0.1 0.12
Golgi 0.05 0.25 0.05 0.05 0 0 0 0 0 0 0 0 0.08 0.07 0.06 – – – 0.15 0.16 0.06 0.12 0.09 0.08
Mitochondria 0.68 0.4 0.23 0.32 0.26 0.44 0.44 0.46 0.62 0.64 0.66 0.72 0.12 0.11 0.05 – – – 0.44 0.41 0.23 0.22 0.26 0.2
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0.23 0.29 0 0 0.05 0.05 0.06 0.05 0 0 0 0 0.07 0.09 0.1 – – – 0 0.11 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 15 15 0 4 1 0 2 0 0 1 1 10 2 1 – – – 8 17 5 6 26 16
Bud 2 3 11 4 2 2 5 11 8 16 3 19 2 3 0 – – – 2 4 8 2 20 25
Bud Neck 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 – – – 3 1 2 0 3 11
Bud Site 0 0 0 0 0 1 1 2 0 1 0 1 0 0 0 – – – – – – – – –
Cell Periphery 9 20 6 4 6 3 6 8 4 3 2 1 9 11 9 – – – 0 0 1 0 1 0
Cytoplasm 15 27 233 126 249 275 348 319 149 220 113 211 176 316 262 – – – 1 4 188 68 121 116
Endoplasmic Reticulum 5 14 17 1 3 8 2 5 9 3 5 4 10 8 12 – – – 3 4 5 3 6 6
Endosome 34 8 8 2 17 9 12 18 2 2 0 0 16 31 15 – – – 70 38 19 15 42 46
Golgi 13 57 18 9 9 1 1 3 0 1 1 0 21 30 21 – – – 47 45 20 20 36 28
Mitochondria 188 92 79 57 94 191 253 257 179 281 152 338 33 50 19 – – – 141 118 81 38 104 72
Nucleus 2 2 1 0 1 1 1 1 2 2 3 3 1 0 0 – – – 1 0 0 0 0 1
Nuclear Periphery 1 0 1 0 1 6 4 4 5 5 5 9 0 0 0 – – – 7 2 2 1 5 3
Nucleolus 19 2 0 0 2 4 5 8 3 7 4 4 0 0 0 – – – 0 1 0 0 2 2
Peroxisomes 3 3 1 0 0 0 0 1 1 0 0 0 0 6 1 – – – 6 5 7 4 6 9
SpindlePole 2 1 0 1 1 1 1 3 3 1 3 5 0 2 0 – – – 6 3 7 4 12 12
Vac/Vac Membrane 63 65 10 2 18 23 32 27 9 14 5 10 18 39 34 – – – 12 31 3 2 9 9
Unique Cell Count 276 228 344 180 360 437 578 557 289 437 229 471 264 457 352 320 288 359 173 406 372
Labelled Cell Count 358 309 400 206 407 526 673 669 374 558 297 606 296 498 374 320 288 359 173 406 372


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.1 9.3 5.7 5.5 5.4 4.5 4.5 4.6 4.2 3.9 3.9 3.8 7.8 7.7 7.5 – – – 7.2 7.4 7.9
Std Deviation (1e-4) 1.6 1.6 1.6 2.0 1.9 1.7 1.7 1.6 1.5 1.4 1.4 1.3 2.5 2.2 2.2 – – – 2.3 2.6 2.2
Intensity Change (Log2) – – – -0.04 -0.07 -0.33 -0.36 -0.3 -0.43 -0.56 -0.55 -0.57 0.45 0.43 0.39 – – – 0.33 0.37 0.47

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -2.8 -2.7 0 0 0 0 0 0 0 -0.4 -3.8 -3.6 – – –
Bud -0.6 -2.6 0 0 0 0 0 0 0 -2.1 -2.7 -3.4 – – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Cell Periphery 0 -0.1 0 0 0 0 0 0 0 1.3 0.6 0.7 – – –
Cytoplasm 0.5 0.4 -1.4 -2.3 -3.1 -4.1 -4.9 -4.4 -6.5 -0.3 0.4 1.9 – – –
Endoplasmic Reticulum -2.6 -3.3 0 0 0 0 0 0 0 -0.7 -2.6 -1.0 – – –
Endosome 0 1.7 0 0 0 0 0 0 0 2.3 2.9 1.4 – – –
Golgi -0.1 -1.9 0 0 0 0 0 0 0 1.4 0.8 0.4 – – –
Mitochondria 2.2 1.0 0 0 0 0 0 0 0 -3.3 -4.6 -6.7 – – –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 – – –
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 – – –
Vacuole 0 1.4 1.6 1.9 1.4 0.2 0.2 -0.5 -0.7 2.3 3.3 3.7 – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.0735 6.4505 6.0751 5.9635 5.5417 6.0617 6.8222 7.3944 7.7226 6.5769 7.0518 7.5384 8.3708 9.6822 9.6348 9.5814 8.6258 9.4223
Actin 0.0344 0.061 0.0425 0.0692 0.0053 0.0116 0.0396 0.0423 0.0356 0.0252 0.0164 0.0209 0.0793 0.0725 0.0501 0.0549 0.0831 0.0559
Bud 0.005 0.009 0.003 0.0104 0.0151 0.0017 0.0017 0.0038 0.0017 0.0021 0.0017 0.0006 0.0033 0.0065 0.0026 0.0096 0.0028 0.0012
Bud Neck 0.0086 0.0031 0.0075 0.0011 0.0008 0.0085 0.0037 0.0008 0.0006 0.0004 0.0004 0.0015 0.0044 0.0049 0.0015 0.0015 0.001 0.0016
Bud Periphery 0.0074 0.0088 0.0049 0.0192 0.0267 0.0043 0.0024 0.0027 0.0015 0.0035 0.0065 0.0011 0.0058 0.0085 0.0029 0.0238 0.0043 0.0023
Bud Site 0.0095 0.0709 0.0125 0.0019 0.0102 0.0012 0.0107 0.0182 0.01 0.0016 0.0019 0.0013 0.017 0.0356 0.0134 0.0041 0.0034 0.0025
Cell Periphery 0.0009 0.003 0.0015 0.0006 0.0017 0.0006 0.0009 0.0003 0.0006 0.0002 0.0013 0.0011 0.0035 0.0015 0.0005 0.0051 0.0003 0.0009
Cytoplasm 0.003 0.0165 0.0084 0.0023 0.0067 0.0016 0.0281 0.0263 0.014 0.0031 0.0077 0.0035 0.0052 0.0251 0.026 0.0223 0.0036 0.0043
Cytoplasmic Foci 0.0202 0.061 0.0277 0.0232 0.0133 0.0202 0.0423 0.0656 0.0466 0.0368 0.0593 0.0309 0.0384 0.0674 0.0391 0.0289 0.0379 0.0227
Eisosomes 0.0008 0.0007 0.0008 0.0007 0.0002 0.0003 0.0008 0.0003 0.0006 0.0005 0.001 0.0004 0.0024 0.0008 0.0004 0.0008 0.0003 0.0018
Endoplasmic Reticulum 0.0057 0.0011 0.003 0.0014 0.0008 0.0031 0.003 0.0014 0.0008 0.0003 0.006 0.0014 0.0065 0.0033 0.009 0.0226 0.0012 0.0041
Endosome 0.0814 0.1335 0.0779 0.0348 0.0676 0.0813 0.0989 0.1229 0.0821 0.0419 0.1316 0.0632 0.1206 0.1475 0.106 0.1453 0.0943 0.0774
Golgi 0.0733 0.1122 0.1057 0.0813 0.1088 0.1211 0.154 0.2134 0.1518 0.1685 0.2152 0.1841 0.1663 0.2452 0.1579 0.1865 0.2297 0.2014
Lipid Particles 0.0367 0.0079 0.007 0.0062 0.0065 0.0116 0.0298 0.0031 0.0052 0.0131 0.006 0.0076 0.0263 0.011 0.0099 0.0021 0.0332 0.0086
Mitochondria 0.6085 0.465 0.6411 0.7227 0.7096 0.696 0.5141 0.4614 0.6211 0.6608 0.4957 0.6482 0.454 0.3326 0.5525 0.4721 0.4741 0.5874
None 0.0149 0.0007 0.0005 0.0023 0.0003 0.0002 0.0098 0.0003 0.0004 0.0002 0.0011 0.0002 0.0034 0.0005 0.0013 0.0009 0.0003 0.0004
Nuclear Periphery 0.0164 0.0005 0.0021 0.0005 0.0002 0.0022 0.005 0.0002 0.0002 0.0001 0.0011 0.0001 0.0046 0.0006 0.0038 0.0036 0.0007 0.0053
Nucleolus 0.0069 0.0009 0.0006 0.0002 0.0022 0.0002 0.0024 0.0002 0.0001 0.0001 0.0001 0.0002 0.004 0.0008 0.0002 0.0001 0.0001 0.0002
Nucleus 0.0079 0.001 0.0014 0.0003 0.0007 0.0005 0.0041 0.0002 0.0002 0.0001 0.0004 0.0002 0.0019 0.0008 0.0008 0.0006 0.0002 0.0018
Peroxisomes 0.0194 0.0247 0.0151 0.014 0.0083 0.0124 0.0196 0.0304 0.0229 0.0394 0.0407 0.0289 0.0227 0.0181 0.0078 0.0042 0.0242 0.01
Punctate Nuclear 0.0076 0.0005 0.0007 0.0006 0.0001 0.0001 0.0162 0.0002 0.0002 0.0001 0.0003 0.0003 0.005 0.0005 0.0016 0.0002 0.0004 0.0004
Vacuole 0.0149 0.0123 0.0232 0.0037 0.0106 0.0113 0.0084 0.0035 0.0017 0.0008 0.0025 0.0017 0.0125 0.0098 0.0071 0.0056 0.002 0.0038
Vacuole Periphery 0.0168 0.0056 0.0129 0.0033 0.0043 0.0101 0.0046 0.0025 0.002 0.001 0.0031 0.0027 0.0127 0.0064 0.0055 0.0052 0.0029 0.0059

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.0852 18.9688 20.6443 21.7961 10.5462 11.3107 15.8229 18.9856 16.2169 15.1169
Translational Efficiency 0.8978 1.0329 1.0291 0.915 1.1385 0.6305 1.0801 0.9472 1.1692 0.791

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
628 1547 347 1352 1488 1665 2073 1498 2116 3212 2420 2850

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 710.12 996.75 1212.63 1099.49 986.71 958.72 1139.26 1152.25 904.62 977.04 1149.78 1127.22
Standard Deviation 91.52 158.52 155.99 162.93 129.53 159.87 151.00 165.60 173.93 160.35 153.89 166.44
Intensity Change Log 2 — 0.489169 0.772005 0.630700 — -0.041517 0.207399 0.223756 — 0.204673 0.470979 0.408198

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000653 0.006647 0.005693 0.041098 0.000780 0.001351 0.007419 0.029012 0.000742 0.003902 0.007171 0.034745
Bud Neck 0.010360 0.002887 0.009678 0.002510 0.002483 0.003926 0.002599 0.002062 0.004821 0.003426 0.003614 0.002275
Bud Site 0.027340 0.044886 0.056053 0.069231 0.017613 0.028035 0.047485 0.061879 0.020500 0.036151 0.048713 0.065366
Cell Periphery 0.000473 0.000391 0.000219 0.001603 0.000197 0.000267 0.000239 0.001081 0.000279 0.000327 0.000236 0.001329
Cytoplasm 0.018358 0.014756 0.011429 0.018373 0.004773 0.012788 0.015565 0.016313 0.008805 0.013735 0.014972 0.017290
Cytoplasmic Foci 0.082262 0.076597 0.145575 0.039480 0.054773 0.069938 0.069292 0.039064 0.062932 0.073145 0.080230 0.039261
Eisosomes 0.000098 0.000091 0.000068 0.000200 0.000040 0.000053 0.000079 0.000179 0.000057 0.000072 0.000077 0.000189
Endoplasmic Reticulum 0.001532 0.001053 0.002260 0.001314 0.000512 0.000548 0.000662 0.000889 0.000815 0.000791 0.000891 0.001090
Endosome 0.091988 0.106240 0.149542 0.044246 0.086268 0.136811 0.077059 0.046520 0.087965 0.122087 0.087452 0.045442
Golgi 0.092181 0.193323 0.145699 0.125799 0.155727 0.156943 0.164129 0.144706 0.136867 0.174465 0.161486 0.135737
Lipid Particles 0.008334 0.001553 0.002622 0.000395 0.001099 0.001324 0.000378 0.000391 0.003247 0.001434 0.000700 0.000393
Mitochondria 0.536930 0.422175 0.073036 0.547573 0.574254 0.421171 0.411141 0.546432 0.563177 0.421655 0.362661 0.546973
Mitotic Spindle 0.019642 0.037519 0.186352 0.038205 0.018195 0.039864 0.108205 0.037486 0.018625 0.038735 0.119410 0.037827
None 0.001651 0.000263 0.000208 0.000319 0.000248 0.000341 0.000253 0.000377 0.000665 0.000303 0.000247 0.000350
Nuclear Periphery 0.000324 0.000104 0.001757 0.000127 0.000191 0.000428 0.000210 0.000501 0.000230 0.000272 0.000432 0.000324
Nuclear Periphery Foci 0.000604 0.000333 0.006278 0.000226 0.000379 0.000750 0.000339 0.000370 0.000446 0.000549 0.001191 0.000301
Nucleolus 0.003741 0.000102 0.001424 0.000124 0.000088 0.000578 0.000108 0.000111 0.001172 0.000349 0.000297 0.000118
Nucleus 0.006240 0.000277 0.003193 0.000535 0.000260 0.000632 0.000308 0.000172 0.002035 0.000461 0.000722 0.000344
Peroxisomes 0.033754 0.023585 0.041321 0.040543 0.011217 0.017416 0.028265 0.027495 0.017905 0.020387 0.030137 0.033685
Vacuole 0.027565 0.037958 0.111470 0.016913 0.032271 0.062080 0.039971 0.023398 0.030874 0.050462 0.050223 0.020322
Vacuole Periphery 0.035971 0.029258 0.046123 0.011186 0.038633 0.044757 0.026294 0.021561 0.037843 0.037292 0.029137 0.016639

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.59 -3.59 -11.82 -9.59 -9.50 -2.04 -7.67 -10.70 -10.46 -7.80 -5.82 -8.42 -15.90 -14.00 -12.15
Bud Neck 5.07 0.19 5.27 0.53 5.77 -1.95 -0.52 0.52 3.43 2.24 2.07 1.52 3.93 3.09 4.67
Bud Site -3.96 -4.68 -8.11 -5.24 -1.91 -4.02 -10.46 -11.54 -8.71 -3.52 -6.75 -10.84 -14.82 -9.70 -4.95
Cell Periphery 0.83 2.81 -3.00 -3.29 -3.77 -2.29 -2.36 -5.88 -5.36 -5.62 -1.27 1.46 -5.45 -5.21 -5.73
Cytoplasm 1.16 1.89 -0.24 -2.06 -2.70 -5.42 -10.01 -7.89 -2.08 -0.65 -3.90 -5.22 -6.77 -2.91 -1.96
Cytoplasmic Foci 1.18 -6.68 8.45 11.21 12.88 -4.55 -4.58 5.36 10.05 10.60 -3.62 -5.41 9.35 15.03 15.54
Eisosomes 1.05 4.42 -8.42 -9.37 -11.45 -4.97 -12.74 -10.93 -9.81 -7.76 -4.48 -6.47 -15.29 -13.47 -12.86
Endoplasmic Reticulum 1.32 -1.53 0.40 -0.57 1.72 -0.47 -2.07 -3.59 -3.27 -2.11 0.13 -0.82 -1.24 -1.37 -0.81
Endosome -2.19 -6.17 7.99 16.01 14.04 -9.84 2.41 10.46 20.82 10.73 -8.80 0.27 13.40 26.13 16.39
Golgi -12.49 -4.61 -4.16 8.90 1.65 -0.11 -1.00 1.59 1.79 2.72 -6.75 -3.99 0.35 7.48 4.54
Lipid Particles 5.00 4.10 6.09 3.16 4.68 -0.43 1.67 1.65 3.09 -0.10 3.34 5.09 5.80 4.41 3.22
Mitochondria 6.75 27.57 -0.49 -8.87 -34.34 12.00 13.61 2.33 -9.26 -10.69 14.11 19.02 1.84 -12.83 -18.00
Mitotic Spindle -5.10 -12.26 -5.14 -0.20 10.82 -6.98 -20.60 -6.58 0.64 14.76 -8.84 -23.83 -8.53 0.33 18.42
None 4.92 5.12 4.73 -2.74 -4.35 -2.88 -0.35 -5.81 -0.93 -6.24 4.14 4.90 3.70 -2.10 -7.53
Nuclear Periphery 2.41 -2.96 1.97 -0.82 3.40 -1.49 -0.45 -1.34 -0.26 -1.23 -0.49 -2.41 -0.77 -0.37 0.78
Nuclear Periphery Foci 2.30 -2.06 3.10 1.29 2.20 -1.61 0.16 0.01 1.67 -0.17 -0.81 -1.86 1.34 2.01 2.23
Nucleolus 3.20 1.94 3.17 -0.25 3.62 -3.54 -1.16 -0.47 3.13 0.10 2.39 2.51 3.07 2.60 2.54
Nucleus 4.21 1.63 3.65 -1.09 2.96 -3.28 -1.53 0.53 3.40 1.78 3.62 2.56 3.19 -0.09 1.40
Peroxisomes 2.62 -1.18 -1.25 -4.42 0.25 -3.11 -7.49 -5.98 -3.52 0.22 -1.23 -5.34 -6.45 -5.61 -1.31
Vacuole -3.52 -9.92 3.34 7.49 11.11 -9.04 -3.63 2.76 11.31 6.39 -8.66 -8.38 4.68 13.44 12.47
Vacuole Periphery 1.93 -1.75 7.68 9.50 7.34 -2.07 5.03 6.66 8.78 2.16 0.27 4.06 10.90 12.44 7.17
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein that associates with mitochondrial ribosome; detected in highly purified mitochondria in high-throughput studies; predicted to be involved in ribosome biogenesis
Localization
Cell Percentages mitochondrion (90%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mrx12

Mrx12


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrx12-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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Images are not yet available