Standard name
Human Ortholog
Description Late endosomal protein involved in late endosome to vacuole transport; functional homolog of human obesity receptor gene-related protein (OB-RGRP)
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.14 0.14 0.22 0.09 0.17 0.11 – 0.07 0.06 0.05 0.06 0 0.18 0.16 0.12 0.12 0.1 0.09 0 0 0 0 0 0
Bud 0 0 0.07 0.06 0 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.75 0.82 0.64 0.64 0.56 0.52 – 0.27 0.43 0.35 0.38 0.37 0.78 0.7 0.78 0.82 0.83 0.76 0.83 0.86 0.85 0.82 0.84 0.85
Cytoplasm 0.26 0.21 0.3 0.23 0.31 0.38 – 0.49 0.4 0.5 0.35 0.37 0.38 0.37 0.38 0.18 0.17 0.27 0.05 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.3 0.18 0.4 0.71 0.47 0.57 – 0.52 0.64 0.56 0.66 0.7 0.18 0.24 0.17 0.09 0.1 0.11 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0.07 0.09 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 64 36 56 23 49 50 – 39 29 20 25 19 40 33 29 25 15 17 7 5 5 2 3 3
Bud 10 6 18 15 10 10 – 21 23 15 12 15 2 4 2 2 2 0 2 1 1 0 1 1
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 0 0 11 5 10 3 8 3
Bud Site 1 0 0 1 2 3 – 1 0 1 0 1 1 1 0 0 0 0 – – – – – –
Cell Periphery 341 214 162 159 161 229 – 141 208 145 146 181 169 144 186 166 131 146 427 254 248 81 170 158
Cytoplasm 117 55 75 57 91 168 – 258 196 208 135 180 82 75 91 37 27 51 25 8 6 2 4 3
Endoplasmic Reticulum 2 0 1 1 5 6 – 4 0 6 3 5 0 2 1 13 10 7 3 4 2 1 4 4
Endosome 2 0 0 0 0 0 – 2 0 0 0 0 0 0 2 0 0 0 8 1 2 0 0 1
Golgi 0 0 0 0 1 0 – 0 0 0 0 0 1 0 0 0 1 4 2 2 0 0 0 1
Mitochondria 134 48 102 175 136 252 – 278 308 233 256 337 39 49 40 19 16 22 7 5 6 0 1 3
Nucleus 2 2 0 0 1 0 – 4 0 2 2 4 0 1 0 3 4 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 4 0 0 1 3 0 0 0 0 1 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 0 1 – 0 2 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes 1 0 0 0 2 4 – 1 2 2 0 0 7 15 21 2 0 1 0 0 0 1 0 0
SpindlePole 6 3 2 1 4 2 – 0 1 2 0 1 2 2 2 1 1 2 0 0 0 0 0 0
Vac/Vac Membrane 10 0 5 4 3 1 – 11 8 2 6 9 0 2 1 7 1 4 10 4 2 1 3 0
Unique Cell Count 453 260 254 248 290 444 530 484 418 385 484 217 205 239 202 157 192 513 297 291 100 203 187
Labelled Cell Count 690 364 421 436 465 726 764 777 636 586 755 344 328 377 275 209 254 513 297 291 100 203 187


Endosome

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.9 7.6 5.1 5.6 6.2 5.2 – 5.2 4.8 5.0 4.7 4.7 7.3 7.6 7.5 9.6 9.5 9.2 7.2 8.0 8.0
Std Deviation (1e-4) 0.7 1.0 1.2 1.3 1.5 1.0 – 1.0 1.1 0.9 1.0 1.0 1.5 1.7 1.7 1.7 1.7 2.1 1.3 1.8 1.8
Intensity Change (Log2) – – – 0.12 0.29 0.02 – 0.02 -0.09 -0.05 -0.11 -0.13 0.51 0.57 0.56 0.9 0.9 0.85 0.49 0.65 0.65


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -3.9 -1.5 -3.8 – -5.9 0 -6.9 0 0 -1.0 -1.6 -2.9 -2.7 -3.3 -3.7
Bud -0.5 -1.9 -3.1 – -1.9 0 -2.0 0 0 -3.3 -2.6 -3.5 -3.2 -2.7 -3.8
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.1 -2.0 -3.1 – -10.0 0 -7.3 0 0 3.3 1.5 3.4 4.3 4.3 2.8
Cytoplasm -1.7 0.5 2.2 – 5.1 2.9 5.2 1.5 2.1 1.9 1.6 2.0 -2.8 -2.8 -0.7
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 0 0 0 3.7 0 0
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 6.8 1.6 4.2 – 3.2 0 3.9 0 0 -5.2 -3.7 -5.7 -7.4 -6.5 -6.7
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 4.4 4.8 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 – 0.1 0 0 0 0 0 0 0 1.0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.7252 3.0299 2.4017 2.8676 1.5294 2.839 2.5367 2.5002 2.3628 2.0076 2.6321 2.8081 3.5985 3.8848 3.6899 4.6547 3.2532 3.8413
Actin 0.0101 0.0001 0.0144 0.0225 0 0.0152 0.0126 0.0005 0.0038 0.0088 0.0008 0.0016 0.0123 0.0001 0.0039 0.0164 0.0001 0.0001
Bud 0.0001 0.0001 0.0003 0.0004 0 0.0001 0.0006 0.0001 0.0007 0.0001 0.0001 0.0004 0.0002 0.0002 0.0003 0.0007 0 0
Bud Neck 0.0004 0.0011 0.0008 0.0012 0.0001 0.0029 0.0012 0.0011 0.0005 0.0002 0.0002 0.0006 0.0004 0.0004 0.0004 0.0002 0.0001 0.0004
Bud Periphery 0.0003 0.0001 0.0003 0.0004 0 0.0002 0.001 0.0001 0.0006 0.0001 0.0001 0.0003 0.0002 0.0003 0.0003 0.001 0 0
Bud Site 0.0008 0.0011 0.0024 0.0043 0 0.0009 0.0028 0.0011 0.0024 0.0004 0.0002 0.0006 0.0013 0.0021 0.001 0.0009 0.0001 0.0001
Cell Periphery 0.0003 0.0002 0.0001 0.0001 0 0.0001 0.0011 0.0001 0.0001 0 0 0.0001 0.0001 0.0001 0.0001 0.0001 0 0
Cytoplasm 0.0034 0.0113 0.0098 0.0009 0.0003 0.0388 0.0082 0.0047 0.0059 0.024 0.0013 0.0057 0.0015 0.0141 0.0034 0.0017 0.0006 0.016
Cytoplasmic Foci 0.1285 0.1431 0.1075 0.0809 0.0932 0.0918 0.1418 0.2032 0.1841 0.1283 0.1245 0.1743 0.1562 0.1971 0.2062 0.1195 0.1543 0.1702
Eisosomes 0.0007 0 0.0001 0.0002 0 0.0001 0.0008 0 0 0 0 0 0.0001 0 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.001 0.0008 0.0032 0.0005 0.0002 0.0008 0.0056 0.0005 0.0015 0.0005 0.0012 0.0013 0.0009 0.0021 0.0006 0.0002 0.0002 0.0013
Endosome 0.4842 0.5229 0.5334 0.5819 0.6265 0.3877 0.5484 0.5387 0.5147 0.6347 0.5768 0.4518 0.4458 0.486 0.4982 0.6671 0.5696 0.4568
Golgi 0.1171 0.1125 0.1484 0.2005 0.0907 0.1099 0.0711 0.0712 0.1284 0.0804 0.0921 0.1094 0.0919 0.0874 0.1206 0.0709 0.106 0.0983
Lipid Particles 0.1602 0.1236 0.0889 0.027 0.1366 0.2961 0.0772 0.0765 0.064 0.0537 0.016 0.1497 0.1664 0.0992 0.0693 0.0669 0.1462 0.1662
Mitochondria 0.0123 0.0023 0.0074 0.0307 0.0013 0.0048 0.0215 0.0089 0.0061 0.0068 0.1211 0.0111 0.0219 0.002 0.0221 0.0116 0.0012 0.0016
None 0.0061 0.0012 0.0053 0.0001 0 0.0007 0.0107 0.0006 0.0025 0.001 0.0001 0.0026 0.0007 0.0151 0.0014 0.0002 0 0.0026
Nuclear Periphery 0.0015 0.0007 0.0031 0.0004 0.0002 0.0014 0.0111 0.0007 0.0015 0.0003 0.0008 0.0057 0.0024 0.0022 0.0003 0.0003 0.0002 0.0004
Nucleolus 0.0014 0.0064 0.0008 0.0001 0.0001 0.0003 0.0032 0.0007 0.0006 0.0003 0.0001 0.0106 0.0003 0.0029 0.0003 0.0001 0.0005 0.0004
Nucleus 0.0008 0.0011 0.0011 0.0001 0 0.0005 0.0021 0.0005 0.0003 0.0002 0.0001 0.003 0.0007 0.0006 0.0003 0.0001 0.0001 0.0001
Peroxisomes 0.021 0.0141 0.0262 0.0245 0.0222 0.0168 0.0346 0.0468 0.0638 0.0244 0.0566 0.0479 0.0717 0.0507 0.0497 0.0254 0.0144 0.0693
Punctate Nuclear 0.01 0.0008 0.0033 0.0003 0.0003 0.0013 0.0082 0.0059 0.0025 0.001 0.0003 0.0035 0.0037 0.0052 0.0012 0.0006 0.0006 0.0018
Vacuole 0.0296 0.0424 0.0283 0.0104 0.0179 0.011 0.0266 0.0311 0.011 0.0177 0.0044 0.0114 0.0156 0.025 0.0168 0.0104 0.0031 0.0103
Vacuole Periphery 0.0102 0.0141 0.0148 0.0126 0.0102 0.0185 0.0097 0.007 0.005 0.0171 0.003 0.0082 0.0059 0.007 0.0034 0.0057 0.0028 0.0039

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 36.5193 34.9779 29.4158 63.5096 27.0565 31.2849 45.3865 65.2439 45.686 52.1444
Translational Efficiency 1.8864 1.3723 1.8433 0.6249 1.7794 3.1288 1.4913 1.0782 1.6771 1.471

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
349 1194 2435 860 840 1775 140 256 1189 2969 2575 1116

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 602.02 844.47 1293.97 976.45 727.82 847.74 1167.55 1137.79 690.89 846.42 1287.10 1013.46
Standard Deviation 107.55 122.22 216.06 177.42 124.65 127.77 162.32 211.49 132.87 125.58 215.40 197.78
Intensity Change Log 2 — 0.488235 1.103921 0.697735 — 0.220040 0.681831 0.644581 — 0.347656 0.888297 0.668886

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000413 0.000357 0.000254 0.001375 0.000425 0.000472 0.000368 0.001276 0.000421 0.000426 0.000260 0.001352
Bud Neck 0.041212 0.003320 0.003178 0.005785 0.011285 0.005331 0.004005 0.003290 0.020069 0.004522 0.003223 0.005212
Bud Site 0.018784 0.008693 0.004032 0.019055 0.022973 0.008113 0.008391 0.034002 0.021743 0.008346 0.004269 0.022484
Cell Periphery 0.000237 0.000076 0.000166 0.000085 0.000314 0.000099 0.000072 0.000131 0.000291 0.000090 0.000161 0.000096
Cytoplasm 0.096495 0.012697 0.000951 0.017939 0.020294 0.012259 0.001713 0.019009 0.042661 0.012435 0.000992 0.018184
Cytoplasmic Foci 0.192511* 0.142640 0.031939 0.127093 0.134590 0.123848 0.154639 0.149334 0.151591 0.131406 0.038610 0.132195
Eisosomes 0.000165 0.000031 0.000019 0.000023 0.000063 0.000032 0.000020 0.000023 0.000093 0.000032 0.000019 0.000023
Endoplasmic Reticulum 0.000856 0.000656 0.000420 0.000729 0.000845 0.000832 0.000309 0.000316 0.000848 0.000761 0.000414 0.000634
Endosome 0.402149* 0.521884* 0.152272 0.391614* 0.445005* 0.487276* 0.560997* 0.352751* 0.432426* 0.501194* 0.174494 0.382699*
Golgi 0.032507 0.110156* 0.094481 0.093653 0.089151 0.105322 0.067401 0.196569* 0.072524 0.107266 0.093009 0.117261*
Lipid Particles 0.028776 0.006831 0.006998 0.006417 0.003018 0.005619 0.008081 0.001241 0.010578 0.006106 0.007056 0.005230
Mitochondria 0.010603 0.025975 0.035999 0.007275 0.025816 0.034843 0.003516 0.012237 0.021351 0.031277 0.034233 0.008413
Mitotic Spindle 0.002013 0.013128 0.013905 0.054308 0.005002 0.008211 0.014087 0.024545 0.004124 0.010189 0.013915 0.047481
None 0.009347 0.000273 0.000263 0.000242 0.000228 0.000303 0.000013 0.000070 0.002905 0.000291 0.000249 0.000203
Nuclear Periphery 0.000617 0.000433 0.007602 0.002011 0.000199 0.000437 0.000452 0.000154 0.000322 0.000435 0.007213 0.001585
Nuclear Periphery Foci 0.001740 0.001274 0.013275 0.008051 0.000967 0.001645 0.004433 0.000811 0.001194 0.001496 0.012795 0.006390
Nucleolus 0.008159 0.001629 0.002996 0.001429 0.002031 0.000854 0.000475 0.000151 0.003830 0.001166 0.002859 0.001136
Nucleus 0.025518 0.001343 0.001212 0.001524 0.004150 0.002163 0.001425 0.000278 0.010422 0.001833 0.001223 0.001238
Peroxisomes 0.038174 0.009957 0.001650 0.011048 0.011079 0.010212 0.025879 0.017206 0.019032 0.010110 0.002968 0.012460
Vacuole 0.080222 0.096160 0.334841* 0.215240* 0.140332 0.122036 0.120590 0.153765 0.122688 0.111630 0.323193* 0.201138*
Vacuole Periphery 0.009502 0.042488 0.293547* 0.035103 0.082234 0.070092 0.023136 0.032838 0.060885 0.058991 0.278845* 0.034584

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.21 0.66 -1.66 -1.82 -2.07 -0.16 0.31 -2.19 -1.94 -2.44 0.00 1.08 -2.12 -2.09 -2.56
Bud Neck 6.71 6.73 6.05 -3.63 -3.85 3.51 3.75 4.71 2.04 0.74 7.52 8.20 6.61 -1.81 -3.63
Bud Site 2.92 4.45 -0.61 -5.55 -8.57 6.30 4.19 -1.86 -4.56 -4.08 6.86 9.22 -0.88 -7.53 -9.72
Cell Periphery 5.28 2.34 4.73 -0.96 6.26 3.43 3.83 2.74 -0.96 -1.76 4.48 2.90 4.24 -0.65 5.25
Cytoplasm 8.18 9.44 6.75 -3.90 -8.49 3.16 8.59 -0.33 -2.15 -4.78 8.34 11.99 4.26 -4.62 -9.76
Cytoplasmic Foci 4.85 16.57 6.68 3.28 -19.66 1.71 -1.34 -1.21 -2.39 0.44 3.81 23.00 3.82 0.66 -20.88
Eisosomes 5.96 6.54 6.29 1.77 -1.91 3.28 4.58 4.31 1.72 -0.41 6.53 8.12 7.48 2.34 -2.09
Endoplasmic Reticulum 0.89 2.03 0.29 -0.93 -3.01 0.12 4.17 4.37 3.10 -0.11 0.68 4.37 1.32 0.63 -2.78
Endosome -6.80 14.79 1.50 12.56 -22.32 -3.63 -4.65 5.49 8.43 7.89 -7.15 27.49 5.82 14.60 -21.42
Golgi -14.61 -14.06 -9.15 3.52 1.24 -2.89 2.39 -6.58 -5.60 -7.29 -8.15 -4.62 -6.10 -0.56 -2.96
Lipid Particles 4.37 4.43 4.36 0.09 0.19 -2.83 -1.61 2.66 5.08 2.14 2.70 2.17 2.75 0.52 1.24
Mitochondria -5.69 -10.34 1.94 7.33 12.42 -2.81 6.85 3.30 5.76 -2.07 -4.19 -4.89 6.07 11.86 11.58
Mitotic Spindle -5.26 -10.01 -10.81 -8.15 -8.34 -2.24 -2.03 -3.82 -3.20 -1.71 -4.72 -7.55 -10.95 -9.40 -8.49
None 2.85 2.86 2.85 -0.01 -0.19 -0.67 2.44 1.71 3.08 -2.01 2.78 2.82 2.84 0.82 0.31
Nuclear Periphery 1.07 -11.93 -3.04 -3.55 7.78 -2.07 -1.65 0.18 3.47 2.13 -1.17 -12.70 -3.67 -3.40 8.83
Nuclear Periphery Foci 1.19 -11.15 -3.89 -4.23 2.59 -1.07 -1.56 0.38 1.91 1.68 -0.57 -11.67 -4.03 -3.93 3.92
Nucleolus 2.49 1.98 2.46 -0.23 2.28 1.43 1.93 2.49 2.80 2.04 2.75 1.14 2.61 -0.32 3.12
Nucleus 4.78 4.80 4.64 -1.64 -2.21 1.20 1.43 2.30 2.18 0.84 4.45 4.86 4.61 0.28 -1.45
Peroxisomes 5.68 7.57 5.45 -0.67 -7.74 0.62 -3.15 -1.46 -1.76 1.65 4.84 9.17 3.13 -1.60 -7.22
Vacuole -1.75 -28.24 -12.95 -14.28 11.29 2.35 0.87 -1.83 -3.30 -2.04 1.79 -30.32 -10.47 -13.56 13.14
Vacuole Periphery -11.79 -58.76* -9.01 2.84 50.54* 2.12 8.17 7.71 7.43 -1.33 0.45 -37.28 6.74 9.27 49.48*
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Late endosomal protein involved in late endosome to vacuole transport; functional homolog of human obesity receptor gene-related protein (OB-RGRP)
Localization
Cell Percentages vacuole (20%), Golgi (8%), mixed (24%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Vps55

Vps55


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Vps55-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available