Standard name
Human Ortholog
Description Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad16p) during NER; required for repair of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0.05 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.69 0.72 0.85 0.86 0.69 0.54 0.44 – 0.28 0.27 0.24 0.27 0.84 0.84 0.79 0.06 0 0.05 0.49 0.43 0.51 0.66 0.53 0.62
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.14 0 0 0 0 0.12 0.19 – 0.32 0.26 0.47 0.25 0 0 0 0.05 0.06 0 0.14 0.12 0.14 0 0 0
Nucleus 0.15 0.26 0.12 0.13 0.23 0.35 0.42 – 0.51 0.54 0.51 0.56 0.14 0.14 0.19 0.86 0.88 0.9 0.16 0.22 0.14 0.12 0.22 0.12
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0
Vac/Vac Membrane 0.08 0 0 0 0.07 0.07 0 – 0 0 0 0 0 0 0 0.05 0.05 0.07 0.11 0.13 0.11 0.08 0.11 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 – 0 0 0 0 0 0 0 1 0 0 1 2 1 0 0 1
Bud 2 0 0 0 0 1 0 – 3 3 5 4 1 0 0 0 1 1 0 0 1 0 0 3
Bud Neck 1 0 10 4 2 1 7 – 3 3 1 4 0 0 1 0 0 0 0 1 1 0 0 1
Bud Site 0 0 0 0 0 1 0 – 10 7 10 7 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 0 1 2 0 0 1 – 1 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0
Cytoplasm 128 41 185 230 180 194 150 – 99 87 103 110 113 117 126 14 6 10 112 42 115 27 48 79
Endoplasmic Reticulum 0 0 0 1 0 0 0 – 0 0 0 0 2 0 1 5 3 4 7 0 2 0 0 0
Endosome 5 0 1 0 1 0 0 – 3 3 1 0 0 1 0 2 5 0 2 1 1 0 0 1
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 2 1 0 0 0 0 0
Mitochondria 26 1 0 4 3 44 63 – 111 83 200 105 0 0 1 12 14 5 31 11 31 0 1 4
Nucleus 27 15 27 34 60 123 142 – 181 170 217 230 19 20 30 211 191 180 35 21 31 4 20 14
Nuclear Periphery 3 0 0 0 0 0 0 – 2 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1 0 0 0 1 0 2 – 9 7 24 12 0 0 0 3 4 0 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 2 0 1 1 4 0 7 – 5 10 3 13 0 0 2 2 2 0 5 1 2 2 2 4
Vac/Vac Membrane 14 2 4 4 17 24 11 – 5 6 10 8 1 5 3 13 11 13 25 12 25 3 10 11
Unique Cell Count 185 57 218 268 260 356 338 352 317 426 413 135 140 159 244 216 200 231 98 228 41 91 129
Labelled Cell Count 212 59 230 280 268 388 383 432 379 577 494 136 143 164 264 237 215 231 98 228 41 91 129


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.5 5.0 5.1 4.7 5.3 4.3 4.4 – 4.2 4.4 3.9 4.2 5.1 5.3 5.3 8.0 7.6 7.2 – 4.8 5.5
Std Deviation (1e-4) 0.6 1.3 1.0 1.4 1.4 0.9 1.3 – 1.0 1.2 1.3 1.2 1.7 1.3 1.5 1.6 1.5 1.5 – 1.3 1.9
Intensity Change (Log2) – – – -0.1 0.05 -0.25 -0.19 – -0.27 -0.21 -0.37 -0.26 0.02 0.06 0.05 0.65 0.59 0.51 – -0.08 0.11

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 -2.7 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.3 -4.0 -7.5 -9.5 – -13.2 -13.1 -14.7 -13.9 -0.3 -0.3 -1.4 -17.1 -17.2 -16.3
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0 0 0 0 0 0 0 3.3 3.8 0
Nucleus 0.1 3.0 5.9 7.4 – 9.4 9.7 9.5 10.5 0.5 0.5 1.7 15.9 15.8 15.9
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 2.5 2.6 1.0 – 0 0 0 0 0 0 0 2.0 1.9 2.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.5694 -0.9179 -0.7958 -0.9099 -1.2764 -0.7836 -0.9765 -0.5805 -0.9215 -0.9372 -1.3287 -0.9759 -0.2467 -0.9938 -0.8097 -1.1097 -0.7618 -1.0241
Actin 0.0473 0.0002 0.0016 0.0016 0.0007 0.0015 0.0131 0.0001 0.0131 0.0008 0.0011 0.0007 0.0542 0.002 0.0088 0.0319 0.1215 0.0005
Bud 0.0007 0.0023 0.0002 0.0001 0.0019 0.0001 0.0012 0.0004 0.0009 0.0027 0.0001 0.0013 0.003 0.001 0.0007 0.0117 0.001 0.0002
Bud Neck 0.0056 0.0004 0.0002 0.0002 0.0009 0.0016 0.0005 0.0008 0.0006 0.0014 0.0003 0.0011 0.0088 0.0003 0.0009 0.0019 0.0005 0.0011
Bud Periphery 0.0016 0.0037 0.0003 0.0001 0.0013 0.0002 0.001 0.0002 0.0025 0.0023 0.0001 0.0052 0.0061 0.0029 0.0008 0.0062 0.0019 0.0002
Bud Site 0.003 0.0061 0.0022 0.0001 0.0006 0.0002 0.0043 0.0087 0.0014 0.0332 0.0001 0.0005 0.0112 0.0203 0.013 0.0037 0.0014 0.0001
Cell Periphery 0.0002 0.0001 0 0 0.0001 0 0.0003 0.0002 0.0001 0.0003 0 0.0001 0.0009 0.0002 0.0003 0.0004 0.0002 0
Cytoplasm 0.0414 0.0435 0.0393 0.0339 0.0498 0.0671 0.0235 0.0174 0.044 0.0379 0.029 0.055 0.0417 0.067 0.0491 0.061 0.0431 0.1167
Cytoplasmic Foci 0.0196 0.0105 0.004 0.0144 0.0093 0.0148 0.0117 0.0095 0.0099 0.0288 0.0026 0.0072 0.0421 0.0046 0.0133 0.0175 0.0112 0.0172
Eisosomes 0.0009 0.0001 0.0002 0.0001 0.0001 0.0001 0.0004 0.0001 0.0002 0.0001 0.0002 0.0001 0.0006 0.0002 0.0002 0.0004 0.0005 0.0001
Endoplasmic Reticulum 0.0038 0.0011 0.0011 0.0008 0.0028 0.0015 0.0025 0.0003 0.0018 0.0008 0.0004 0.0004 0.0052 0.0007 0.0013 0.0025 0.0026 0.001
Endosome 0.0097 0.0011 0.001 0.0184 0.0029 0.0021 0.0215 0.0008 0.0166 0.0056 0.0024 0.0055 0.0302 0.0007 0.0115 0.0091 0.0066 0.003
Golgi 0.0052 0.0001 0.0001 0.0004 0.0002 0.0002 0.0063 0.0003 0.0055 0.0024 0.002 0.0007 0.0093 0.0002 0.0048 0.006 0.0177 0.0002
Lipid Particles 0.0092 0.0007 0.0004 0.0016 0.0006 0.0006 0.0067 0.0063 0.0037 0.0102 0.0045 0.0093 0.0308 0.0003 0.0046 0.0082 0.0568 0.0007
Mitochondria 0.0021 0.0006 0.0004 0.0005 0.0013 0.0005 0.0352 0.0004 0.0016 0.002 0.0788 0.0015 0.0148 0.0009 0.0109 0.0107 0.012 0.0006
None 0.6718 0.8021 0.8318 0.7207 0.7252 0.7657 0.7534 0.8222 0.7514 0.6282 0.6707 0.7536 0.5437 0.8124 0.7393 0.7393 0.5709 0.6433
Nuclear Periphery 0.0093 0.0038 0.0022 0.0048 0.0119 0.0041 0.0101 0.0016 0.0027 0.0026 0.0022 0.0011 0.0126 0.0008 0.0034 0.0083 0.0018 0.0027
Nucleolus 0.0021 0.0029 0.0015 0.003 0.0047 0.0021 0.0038 0.0057 0.0034 0.0049 0.0033 0.0027 0.0053 0.0007 0.0016 0.0039 0.0044 0.0022
Nucleus 0.112 0.1048 0.0976 0.1726 0.1389 0.1233 0.0876 0.1049 0.1208 0.2021 0.1829 0.1342 0.1238 0.0803 0.1064 0.0589 0.1019 0.1848
Peroxisomes 0.0099 0.0005 0.0003 0.0033 0.0004 0.0011 0.0055 0.0005 0.005 0.0108 0.0056 0.0013 0.0346 0.0012 0.013 0.007 0.0397 0.0008
Punctate Nuclear 0.0425 0.0145 0.0149 0.0199 0.0432 0.0122 0.0085 0.0188 0.0138 0.0184 0.0134 0.0165 0.0105 0.0024 0.0122 0.0063 0.0025 0.0225
Vacuole 0.0015 0.0008 0.0004 0.0027 0.0026 0.0007 0.0017 0.0008 0.001 0.0041 0.0002 0.0018 0.008 0.0011 0.0036 0.0038 0.0013 0.0016
Vacuole Periphery 0.0006 0.0002 0.0001 0.0007 0.0007 0.0002 0.0012 0.0001 0.0002 0.0005 0.0002 0.0002 0.0026 0.0001 0.0003 0.0013 0.0005 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.473 5.809 6.0348 9.808 7.5827 5.8452 9.6913 10.9016 11.0707 10.8481
Translational Efficiency 1.0364 1.6624 1.2989 0.9118 1.2055 2.0837 1.1621 1.0087 1.0473 1.0746

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
943 1437 420 664 1713 1838 285 762 2656 3275 705 1426

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 612.77 691.19 951.92 824.13 663.96 687.24 896.59 798.69 645.79 688.97 929.55 810.54
Standard Deviation 85.56 107.49 109.20 106.88 75.15 90.68 93.99 112.99 82.71 98.43 106.83 110.91
Intensity Change Log 2 — 0.173737 0.635495 0.427526 — 0.049718 0.433352 0.266539 — 0.110573 0.533909 0.346050

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000182 0.000205 0.000902 0.000609 0.000059 0.000288 0.000258 0.000409 0.000103 0.000251 0.000642 0.000502
Bud Neck 0.002556 0.024643 0.005251 0.013813 0.011071 0.033530 0.001131 0.006798 0.008048 0.029631 0.003586 0.010065
Bud Site 0.001639 0.005712 0.010498 0.019085 0.002153 0.014047 0.000934 0.021086 0.001970 0.010390 0.006632 0.020155
Cell Periphery 0.000291 0.000181 0.000229 0.000205 0.000126 0.000252 0.000150 0.000228 0.000185 0.000221 0.000197 0.000217
Cytoplasm 0.073762 0.387368 0.099236 0.275877 0.476902 0.355885 0.169538 0.360283 0.333769 0.369699 0.127656 0.320980
Cytoplasmic Foci 0.010735 0.186676 0.007407 0.009769 0.171604 0.182800 0.028350 0.010445 0.114488 0.184501 0.015873 0.010130
Eisosomes 0.000041 0.000134 0.000098 0.000056 0.000096 0.000138 0.000090 0.000052 0.000077 0.000136 0.000095 0.000054
Endoplasmic Reticulum 0.001677 0.000873 0.009853 0.005537 0.000645 0.000897 0.003884 0.003807 0.001012 0.000886 0.007440 0.004613
Endosome 0.000691 0.011488 0.003897 0.003114 0.005742 0.022915 0.003459 0.004785 0.003949 0.017901 0.003720 0.004006
Golgi 0.000104 0.001803 0.000120 0.006503 0.001355 0.004248 0.000073 0.001943 0.000911 0.003175 0.000101 0.004067
Lipid Particles 0.002659 0.008473 0.003534 0.001691 0.006879 0.010471 0.004068 0.001379 0.005381 0.009594 0.003750 0.001524
Mitochondria 0.001219 0.008544 0.000988 0.001516 0.002581 0.017223 0.000359 0.001998 0.002097 0.013415 0.000734 0.001773
Mitotic Spindle 0.001193 0.002084 0.001330 0.011520 0.003751 0.008238 0.001149 0.029307 0.002843 0.005538 0.001257 0.021024
None 0.024557 0.011483 0.002911 0.006889 0.004548 0.006811 0.004335 0.013174 0.011652 0.008861 0.003487 0.010247
Nuclear Periphery 0.001055 0.000649 0.002310 0.002202 0.000584 0.000808 0.001708 0.001819 0.000751 0.000738 0.002066 0.001997
Nuclear Periphery Foci 0.000517 0.000467 0.001753 0.001447 0.000333 0.000301 0.001055 0.000896 0.000398 0.000374 0.001471 0.001152
Nucleolus 0.013046 0.003520 0.002378 0.000551 0.001412 0.004616 0.001139 0.001002 0.005542 0.004135 0.001877 0.000792
Nucleus 0.860705 0.291500 0.781931 0.564821 0.278464 0.268657 0.720171 0.461366 0.485186 0.278680 0.756964 0.509539
Peroxisomes 0.000659 0.010953 0.000569 0.000551 0.003301 0.015260 0.000480 0.001161 0.002363 0.013370 0.000533 0.000877
Vacuole 0.002514 0.042214 0.064478 0.071461 0.027918 0.049999 0.057480 0.076310 0.018899 0.046583 0.061649 0.074052
Vacuole Periphery 0.000199 0.001030 0.000329 0.002782 0.000474 0.002615 0.000189 0.001752 0.000376 0.001919 0.000273 0.002231

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.28 -8.66 -4.22 -5.17 4.30 -3.84 -8.08 -11.73 -3.10 -2.43 -3.33 -11.83 -8.98 -5.82 4.00
Bud Neck -10.85 -5.08 -5.19 5.45 -2.44 -10.06 7.62 2.30 12.66 -7.23 -13.57 3.74 -0.93 12.74 -4.75
Bud Site -3.81 -2.45 -3.96 -2.44 -0.48 -8.31 2.23 -4.99 0.15 -5.36 -9.25 -2.26 -6.37 -1.28 -2.51
Cell Periphery 2.87 0.98 2.90 0.00 3.69 -4.18 -1.95 -2.24 2.54 -0.67 -1.57 -1.55 0.59 2.36 2.66
Cytoplasm -33.79 -1.66 -12.26 15.93 -9.98 13.05 24.02 18.94 8.09 -7.06 -4.44 25.29 11.55 16.37 -12.83
Cytoplasmic Foci -30.85 2.50 2.18 32.34 -0.44 -1.67 25.51 34.69 35.61 3.88 -14.19 27.31 31.09 48.12 3.23
Eisosomes -10.86 -9.25 -6.87 6.45 4.69 -4.74 -1.43 5.40 7.78 4.71 -9.67 -6.63 -0.01 10.02 6.90
Endoplasmic Reticulum 4.59 -14.72 -13.45 -15.45 5.05 -2.08 -9.59 -14.60 -13.74 -0.46 1.24 -17.20 -19.88 -20.46 5.07
Endosome -11.81 -10.09 -6.75 9.43 4.42 -11.81 3.45 3.85 13.40 0.96 -15.12 -0.84 2.54 16.21 3.44
Golgi -9.47 -2.55 -1.56 -0.20 -1.52 -4.82 3.90 1.18 5.18 -1.28 -6.25 3.74 -0.60 2.65 -1.89
Lipid Particles -8.25 -2.49 2.25 10.76 5.88 -3.77 4.01 8.59 12.11 5.05 -6.61 3.04 8.75 16.03 7.92
Mitochondria -5.99 1.00 0.47 6.07 -0.46 -9.14 4.06 1.74 10.21 -3.61 -10.64 3.69 1.96 11.87 -2.86
Mitotic Spindle -0.70 -1.34 -4.05 -3.88 -2.82 -2.32 1.84 -4.20 -3.11 -5.07 -2.09 0.08 -5.61 -4.72 -5.38
None 4.32 8.43 7.32 3.41 -3.93 -2.59 1.05 -2.65 -0.89 -3.19 2.23 8.06 4.09 1.94 -4.81
Nuclear Periphery 3.74 -12.05 -13.60 -16.64 -3.05 -2.96 -12.73 -14.59 -12.70 -5.44 -0.11 -18.61 -20.58 -20.13 -5.37
Nuclear Periphery Foci 0.36 -6.17 -4.16 -5.77 2.31 0.94 -6.46 -4.69 -4.94 -0.35 0.54 -9.14 -6.72 -7.57 2.07
Nucleolus 8.86 10.79 12.53 7.53 6.66 -6.36 1.67 1.96 8.23 0.53 2.76 9.20 11.76 11.09 5.69
Nucleus 52.49 7.48 20.71 -20.93 10.07 1.05 -22.99 -18.72 -18.53 8.72 23.36 -19.39 -5.62 -27.73 13.95
Peroxisomes -9.67 1.27 2.21 9.96 1.33 -9.99 5.51 4.86 13.41 -0.25 -13.19 5.53 5.29 16.72 0.37
Vacuole -17.18 -12.05 -18.46 -12.70 -4.44 -8.77 -7.28 -15.01 -11.85 -3.56 -15.63 -12.86 -22.89 -17.28 -5.69
Vacuole Periphery -10.38 -4.15 -1.35 0.14 -1.10 -9.13 5.95 -0.58 4.56 -1.38 -11.21 2.85 -1.33 3.20 -1.65
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad16p) during NER; required for repair of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex
Localization
Cell Percentages nucleus (34%), cytoplasm (25%), mixed (27%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Rad7

Rad7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rad7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available