Standard name
Human Ortholog
Description Methylene-fatty-acyl-phospholipid synthase; catalyzes the last two steps in phosphatidylcholine biosynthesis; also known as phospholipid methyltransferase
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0 0 0 0
Cytoplasm 0.46 0.47 0.37 0.37 0.55 0.57 0.59 0.66 0.67 0.66 0.7 0.67 0.19 0.26 0.23 0.33 0.26 0.32 0.05 0 0 0 0 0
Endoplasmic Reticulum 0.34 0.49 0.5 0.6 0.4 0.37 0.31 0.28 0.24 0.24 0.23 0.22 0.72 0.68 0.66 0 0 0 0.6 0.7 0.69 0.78 0.74 0.66
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.3 0.1 0.19 0 0.06 0 0.1 0.07 0.09 0.11 0.1 0.12 0.12 0.06 0.12 0.64 0.71 0.64 0.31 0.24 0.25 0.17 0.2 0.26
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 1 1 5 5 1 0 4 6 2 3 1 3 1 3 0 0 1 0 1 0 0 0 0
Bud 1 1 1 2 2 6 4 3 2 2 2 4 0 1 1 0 0 0 0 1 0 2 2 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 3 2 9 7 9 11 10 8 10 8 12 2 8 9 1 1 2 0 0 0 0 0 0
Cytoplasm 116 108 52 65 117 131 174 238 199 188 153 178 24 37 36 35 32 33 15 8 3 2 2 2
Endoplasmic Reticulum 87 113 70 105 84 84 91 100 70 69 50 58 92 95 103 1 1 1 176 196 117 166 176 179
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1
Golgi 1 0 0 2 2 0 0 0 0 1 0 0 0 4 1 3 3 4 0 0 0 0 1 2
Mitochondria 0 0 0 1 0 2 3 0 1 2 0 2 0 0 0 0 0 0 1 0 0 0 1 0
Nucleus 1 0 0 0 0 0 0 1 0 0 0 1 0 1 0 3 2 6 0 0 0 0 0 1
Nuclear Periphery 0 0 1 2 0 1 1 0 1 0 1 0 0 0 0 0 1 0 7 2 5 2 2 5
Nucleolus 0 0 0 1 0 1 1 1 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 77 24 26 7 12 9 29 25 26 32 21 31 16 8 19 69 89 65 91 66 43 36 48 71
Unique Cell Count 253 231 140 176 212 228 293 362 295 286 219 267 128 140 155 107 125 102 296 280 171 214 239 271
Labelled Cell Count 286 250 153 199 229 244 314 382 313 306 238 288 137 155 172 112 129 113 296 280 171 214 239 271


Endoplasmic Reticulum, Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 31.8 38.3 21.4 28.3 34.0 31.8 29.8 32.5 31.0 30.1 31.2 29.7 34.2 28.8 26.9 40.8 42.2 45.2 37.3 40.1 38.6
Std Deviation (1e-4) 7.0 9.7 5.7 7.9 9.8 8.7 8.5 7.9 9.2 8.4 9.8 8.7 7.7 8.0 7.2 12.2 12.3 13.3 10.3 12.7 12.1
Intensity Change (Log2) – – – 0.4 0.66 0.57 0.48 0.6 0.53 0.49 0.54 0.47 0.67 0.43 0.33 0.93 0.98 1.07 0.8 0.9 0.85


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 1.9 2.0 0 0 0
Cytoplasm 0 3.3 3.8 4.3 5.8 6.0 5.6 6.1 5.7 -3.3 -1.9 -2.6 -0.7 -2.0 -0.8
Endoplasmic Reticulum 1.7 -1.9 -2.5 -3.8 -4.8 -5.5 -5.4 -5.3 -5.8 3.7 3.0 2.9 -8.4 -9.0 -8.3
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -4.2 -3.8 -4.6 -2.5 -3.9 -2.9 -2.1 -2.5 -1.9 -1.4 -3.3 -1.5 7.3 8.6 7.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 32.2212 38.7672 33.5083 28.3789 32.486 35.2274 39.2674 50.1015 43.6663 40.7836 41.9466 45.3281 37.921 45.4359 38.0212 36.6986 34.1921 41.2838
Actin 0.0082 0.0001 0.0109 0.0003 0.0059 0.0017 0.0078 0 0.0096 0.0001 0.0041 0 0.0001 0 0.0001 0.0001 0 0.0001
Bud 0.0003 0.0001 0.0006 0.0006 0.0006 0.0003 0.0002 0 0.0001 0.0003 0.0003 0.0001 0.0001 0.0001 0.0001 0.0003 0.0001 0.0002
Bud Neck 0.0007 0.0003 0.0007 0.001 0.001 0.0008 0.0003 0.0003 0.0006 0.0014 0.0007 0.0005 0.0003 0.0003 0.0008 0.0006 0.0005 0.0008
Bud Periphery 0.0014 0.0008 0.0016 0.0025 0.0037 0.0018 0.001 0.0005 0.001 0.0023 0.0013 0.0011 0.0007 0.0006 0.0014 0.0021 0.0011 0.0017
Bud Site 0.0014 0.0001 0.0025 0.0031 0.0006 0.0002 0.0002 0 0.0003 0.0002 0.0004 0 0.0001 0 0.0001 0.0003 0.0001 0.0001
Cell Periphery 0.1249 0.17 0.1071 0.1261 0.1037 0.108 0.0796 0.124 0.1267 0.1333 0.1127 0.0691 0.071 0.1284 0.1049 0.0817 0.0807 0.0651
Cytoplasm 0.0093 0.0061 0.0143 0.0092 0.0074 0.0037 0.0098 0.0055 0.0092 0.0072 0.0099 0.0042 0.0063 0.0038 0.0062 0.0049 0.0041 0.0038
Cytoplasmic Foci 0.003 0.0002 0.0092 0.0113 0.008 0.0015 0.0062 0 0.0024 0.0001 0.014 0 0.0001 0 0.0001 0.0001 0.0001 0.0001
Eisosomes 0.0002 0 0.0005 0.0002 0 0 0.0001 0 0.0002 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.255 0.211 0.2683 0.0677 0.0468 0.1333 0.3661 0.4339 0.2922 0.2009 0.1659 0.2651 0.4014 0.4361 0.407 0.3058 0.2586 0.4507
Endosome 0.0076 0.0016 0.0135 0.0094 0.0056 0.0037 0.0082 0.0009 0.0043 0.0027 0.0097 0.002 0.0027 0.0006 0.0023 0.0103 0.0029 0.0032
Golgi 0.0017 0.0001 0.0037 0.0023 0.003 0.0004 0.0007 0 0.0006 0.0001 0.0017 0.0001 0.0002 0 0.0001 0.0004 0.0001 0.0002
Lipid Particles 0.007 0.0045 0.0101 0.0081 0.0255 0.0057 0.0083 0.0033 0.0117 0.0035 0.0083 0.0029 0.0066 0.0039 0.0033 0.0021 0.0058 0.0081
Mitochondria 0.0082 0.0001 0.002 0.0103 0.0018 0.002 0.0019 0.0001 0.0012 0.0003 0.0004 0.0001 0.0008 0 0.0002 0.0007 0.0002 0.0003
None 0.0006 0 0.0079 0.0042 0.0005 0.0011 0.0045 0 0.003 0.0001 0.0024 0 0.0001 0 0 0.0001 0 0
Nuclear Periphery 0.0957 0.0458 0.0461 0.0303 0.0408 0.0713 0.13 0.0543 0.0626 0.0884 0.1067 0.1121 0.2201 0.0767 0.0787 0.0793 0.087 0.1252
Nucleolus 0.0034 0.0017 0.0038 0.0082 0.0013 0.0057 0.0091 0.0002 0.0026 0.0009 0.002 0.0004 0.0052 0.0001 0.0004 0.0049 0.0012 0.0006
Nucleus 0.0096 0.0036 0.0079 0.0094 0.0061 0.009 0.0119 0.0032 0.0045 0.0065 0.0142 0.0037 0.0122 0.0026 0.0032 0.0095 0.0046 0.0077
Peroxisomes 0.0005 0 0.0039 0.0011 0.046 0.0001 0.0004 0 0.0011 0 0.0031 0 0 0 0 0 0 0
Punctate Nuclear 0.0006 0.0001 0.0094 0.0006 0.0046 0.001 0.0035 0 0.0008 0 0.0062 0 0.0002 0 0 0 0 0.0001
Vacuole 0.4168 0.5292 0.4449 0.6471 0.6192 0.592 0.3073 0.3579 0.4263 0.5015 0.4875 0.4777 0.2421 0.3269 0.3637 0.4336 0.4637 0.2975
Vacuole Periphery 0.0442 0.0247 0.031 0.0467 0.068 0.0567 0.0428 0.0159 0.039 0.0503 0.0487 0.061 0.0296 0.0197 0.0274 0.0634 0.0891 0.0347

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 163.4673 127.0694 90.7551 85.4827 85.2378 159.8252 111.6168 103.5162 139.4716 106.8394
Translational Efficiency 1.2524 1.1493 0.9656 1.3972 0.9821 1.5155 0.991 1.0841 0.9215 0.8619

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
158 1633 1536 142 2030 1582 2206 1459 2188 3215 3742 1601

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2179.08 2408.51 3362.10 2853.64 2209.76 2065.47 2893.21 3148.59 2207.54 2239.71 3085.68 3122.43
Standard Deviation 618.63 638.46 784.64 768.49 505.89 502.20 785.66 1050.69 514.92 600.47 818.42 1032.20
Intensity Change Log 2 — 0.144422 0.625643 0.389084 — -0.097420 0.388781 0.510816 — 0.027719 0.511242 0.451659

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000065 0.000102 0.000174 0.000081 0.000077 0.000183 0.000350 0.000182 0.000076 0.000142 0.000278 0.000173
Bud Neck 0.001029 0.000650 0.005314 0.005306 0.000591 0.000518 0.003839 0.002348 0.000623 0.000585 0.004444 0.002611
Bud Site 0.000613 0.001192 0.001432 0.003211 0.000905 0.001559 0.005870 0.004364 0.000884 0.001372 0.004048 0.004262
Cell Periphery 0.059177 0.009938 0.013580 0.055095 0.009695 0.014291 0.010792 0.037022 0.013268 0.012080 0.011936 0.038625
Cytoplasm 0.005743 0.008150 0.006578 0.006618 0.004687 0.006548 0.023505 0.007524 0.004763 0.007362 0.016557 0.007443
Cytoplasmic Foci 0.000545 0.000721 0.000319 0.000482 0.000268 0.000896 0.001792 0.001179 0.000288 0.000807 0.001187 0.001117
Eisosomes 0.000014 0.000017 0.000039 0.000084 0.000013 0.000015 0.000040 0.000091 0.000013 0.000016 0.000040 0.000090
Endoplasmic Reticulum 0.339221* 0.879553* 0.479752* 0.520646* 0.820787* 0.817371* 0.718610* 0.775672* 0.786012* 0.848955* 0.620565* 0.753053*
Endosome 0.007770 0.008867 0.016366 0.018332 0.007352 0.009493 0.019030 0.014782 0.007382 0.009175 0.017937 0.015097
Golgi 0.001525 0.003101 0.003122 0.011334 0.001044 0.001841 0.002680 0.007681 0.001078 0.002481 0.002861 0.008005
Lipid Particles 0.002888 0.003334 0.010408 0.042224 0.002143 0.002549 0.013719 0.032499 0.002197 0.002948 0.012360 0.033362
Mitochondria 0.000078 0.000318 0.000718 0.000156 0.000241 0.000939 0.000984 0.000545 0.000230 0.000624 0.000875 0.000511
Mitotic Spindle 0.000023 0.000066 0.000104 0.000492 0.000017 0.000420 0.001289 0.000369 0.000018 0.000240 0.000803 0.000380
None 0.000023 0.001728 0.000339 0.000139 0.000285 0.000675 0.001126 0.000685 0.000266 0.001210 0.000803 0.000636
Nuclear Periphery 0.002755 0.003386 0.053624 0.009355 0.003276 0.001786 0.014656 0.003304 0.003239 0.002599 0.030651 0.003841
Nuclear Periphery Foci 0.017078 0.010974 0.059068 0.038770 0.005402 0.006482 0.039091 0.009356 0.006245 0.008764 0.047291 0.011965
Nucleolus 0.000073 0.000031 0.000140 0.000055 0.000039 0.000108 0.000146 0.000045 0.000042 0.000069 0.000143 0.000046
Nucleus 0.000449 0.000249 0.000804 0.000463 0.000222 0.000337 0.002948 0.000505 0.000239 0.000292 0.002068 0.000501
Peroxisomes 0.000038 0.000019 0.000009 0.000013 0.000032 0.000081 0.000059 0.000096 0.000032 0.000050 0.000038 0.000089
Vacuole 0.534564* 0.063006 0.322893* 0.269641* 0.136904 0.129932 0.133200 0.096408 0.165620 0.095938 0.211065* 0.111773
Vacuole Periphery 0.026327 0.004598 0.025217 0.017502 0.006019 0.003976 0.006274 0.005342 0.007486 0.004292 0.014050 0.006421

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.18 -4.43 -0.96 0.60 3.77 -1.62 -2.54 -2.82 -0.24 1.71 -1.64 -3.13 -2.84 -0.99 1.84
Bud Neck 1.30 -9.77 -3.00 -3.29 0.22 0.61 -9.29 -4.15 -4.37 3.45 0.46 -13.92 -4.83 -5.03 4.31
Bud Site -1.67 -2.61 -1.36 -1.04 -0.75 -1.30 -6.84 -4.49 -3.65 1.93 -1.30 -6.71 -4.66 -4.12 0.25
Cell Periphery 6.03 5.56 0.43 -6.30 -5.75 -3.34 -1.23 -12.71 -9.76 -12.07 0.94 0.98 -11.76 -12.71 -13.02
Cytoplasm -0.91 -0.82 -0.45 -0.14 -0.19 -2.28 -11.63 -3.17 -1.30 8.61 -3.17 -11.36 -3.05 -0.72 6.55
Cytoplasmic Foci -0.46 0.50 0.15 0.90 -0.58 -2.63 -8.05 -3.59 -0.87 2.43 -3.30 -7.51 -3.55 -1.18 0.71
Eisosomes -0.81 -4.56 -5.26 -5.04 -3.11 -0.45 -3.21 -8.33 -8.54 -4.19 -0.73 -4.50 -8.93 -9.05 -5.21
Endoplasmic Reticulum -19.06 -4.30 -4.26 11.80 -1.57 0.42 12.91 5.19 4.54 -6.71 -7.91 20.75 3.88 11.07 -14.36
Endosome -0.91 -6.34 -3.33 -3.16 -0.57 -2.83 -13.69 -8.97 -5.46 4.53 -3.27 -16.26 -9.57 -7.26 3.66
Golgi -2.25 -4.23 -5.13 -4.10 -4.29 -2.05 -4.29 -6.16 -5.20 -4.39 -3.51 -6.40 -6.93 -5.23 -5.02
Lipid Particles -0.46 -5.27 -4.74 -4.70 -3.74 -0.64 -9.29 -12.18 -11.92 -6.30 -1.62 -11.63 -13.06 -12.70 -7.91
Mitochondria -5.21 -5.62 -1.71 2.65 4.85 -1.28 -5.72 -3.65 0.65 3.05 -1.48 -7.23 -3.69 0.29 3.57
Mitotic Spindle -1.02 -2.07 -1.31 -1.18 -0.94 -1.24 -5.08 -1.92 -0.21 2.10 -1.35 -5.32 -2.05 -0.92 1.05
None -2.84 -2.83 -2.13 2.64 1.82 -1.44 -3.34 -1.53 -0.05 1.17 -2.79 -3.33 -1.55 1.39 0.59
Nuclear Periphery -1.18 -21.18 -2.34 -2.12 12.02 4.15 -9.32 -0.10 -6.22 9.50 1.80 -21.58 -1.46 -3.51 21.08
Nuclear Periphery Foci 0.87 -6.12 -2.32 -3.68 2.35 -1.18 -14.85 -4.28 -2.60 12.82 -2.63 -21.91 -4.89 -2.64 17.57
Nucleolus 3.28 -1.36 0.98 -1.29 1.71 -1.33 -4.31 -0.70 1.24 4.12 -1.07 -4.12 -0.51 0.93 3.99
Nucleus 0.71 -1.89 -0.33 -1.02 1.25 -1.69 -6.92 -1.78 -1.50 3.68 -1.13 -7.75 -1.81 -1.67 2.84
Peroxisomes 1.14 1.73 1.47 1.15 -0.68 -1.55 -1.90 -2.15 -0.06 -1.15 -1.15 -0.66 -2.07 -1.01 -1.80
Vacuole 18.04 7.56 7.32 -8.13 2.31 0.93 -1.07 5.27 4.07 6.42 10.62 -7.65 6.73 -3.03 15.49
Vacuole Periphery 5.14 0.31 1.44 -2.60 1.58 3.25 -0.46 0.89 -2.08 1.35 4.80 -7.64 1.24 -2.82 8.34
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Methylene-fatty-acyl-phospholipid synthase; catalyzes the last two steps in phosphatidylcholine biosynthesis; also known as phospholipid methyltransferase
Localization
Cell Percentages ER (88%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

Opi3

Opi3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Opi3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available