Standard name
Human Ortholog
Description Transcriptional activator; binds specific gene recruitment sequences and is required for DNA zip code-mediated targeting of genes to nuclear periphery; regulates proline utilization genes, constitutively binds PUT1 and PUT2 promoters as a dimer, undergoes conformational change to form active state; binds other promoters only under activating conditions; differentially phosphorylated in presence of different nitrogen sources; has a Zn(2)-Cys(6) binuclear cluster domain
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.07 0 0.07 0.07 0.11 0.09 – 0.14 0.11 0.1 0.18 0.19 0.08 0.1 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.08 0.14 0.28 0.08 0.52 0.53 0.59 0.83 – 0.8 0.81 0 0 0.11 0 0 0 0 0 0 0 0 0
Nucleus 0.95 0.91 0.92 0.85 0.87 0.77 0.7 0.59 0.49 – 0.37 0.39 0.88 0.78 0.75 0.83 0.83 0.84 0.87 0.87 0.88 0.88 0.75 0.6
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.05 0 0 0 0.05 0 0 0 0 – 0 0.05 0 0.05 0 0.08 0.06 0.05 0 0.05 0.08 0.06 0.15 0.18
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 4
Bud 0 0 0 0 0 1 0 6 2 – 1 4 0 0 1 0 1 0 2 0 1 2 2 2
Bud Neck 0 0 0 0 0 0 0 3 0 – 0 0 0 0 0 0 0 0 0 0 0 0 1 1
Bud Site 0 0 0 1 1 2 5 7 5 – 2 10 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1 9 5 11 7 14 20 33 20 – 26 18 29 70 77 13 13 11 0 2 0 0 3 2
Endoplasmic Reticulum 0 2 0 0 0 2 0 0 2 – 1 0 0 0 1 2 3 3 0 0 0 0 1 2
Endosome 0 0 1 0 2 0 0 0 0 – 0 0 0 1 0 2 3 2 2 2 0 0 1 6
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 1 1 0 0 1 4
Mitochondria 2 20 24 42 16 102 144 183 176 – 144 136 7 3 44 5 2 3 0 6 1 0 2 8
Nucleus 104 236 159 127 165 152 190 181 103 – 66 65 258 305 304 129 110 117 103 228 152 164 235 155
Nuclear Periphery 0 1 0 1 0 0 1 1 1 – 0 0 0 0 2 0 1 0 1 1 1 0 0 2
Nucleolus 2 2 1 2 5 1 3 1 1 – 0 3 0 2 4 0 2 3 0 0 0 2 8 14
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 1 1 0 0 0 0 0 0 0 0 0 1
SpindlePole 0 1 0 0 1 0 1 0 0 – 0 0 0 2 0 1 3 0 0 1 0 0 3 4
Vac/Vac Membrane 5 7 2 1 9 5 7 10 5 – 6 8 3 21 13 13 8 7 4 13 13 11 48 46
Unique Cell Count 110 258 173 149 189 198 271 308 212 180 168 293 393 408 155 132 139 118 263 174 186 314 260
Labelled Cell Count 114 278 192 185 206 279 371 425 315 246 244 298 405 446 166 146 146 118 263 174 186 314 260


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.6 5.3 4.6 4.5 4.8 3.8 3.9 3.7 3.0 – 3.1 3.1 5.4 5.4 4.6 8.0 8.8 9.0 5.7 5.7 6.6
Std Deviation (1e-4) 1.0 0.9 0.8 1.3 1.0 0.9 1.6 1.7 0.9 – 1.2 1.6 1.0 1.2 1.1 1.6 2.2 1.9 1.3 1.2 1.7
Intensity Change (Log2) – – – -0.02 0.06 -0.28 -0.25 -0.3 -0.59 – -0.56 -0.58 0.23 0.23 0.01 0.81 0.94 0.98 0.32 0.31 0.54

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 1.8 0.4 1.8 2.0 3.1 2.6 – 3.8 2.9 2.8 4.8 5.1 2.2 2.6 2.0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 – 0 0 -4.8 -6.7 0 -3.4 -3.8 -3.7
Nucleus -1.9 -1.4 -4.0 -5.5 -7.7 -9.1 – -10.8 -10.3 -1.3 -4.1 -4.8 -2.4 -2.3 -2.1
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vacuole 0 2.0 0 0 0 0 – 0 0 0 2.3 0 3.1 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.5987 3.3757 3.7876 2.9168 3.4768 3.0259 4.6309 4.5767 4.1642 4.7013 4.5216 4.385 4.4395 4.2674 4.2277 4.0899 4.2314 4.236
Actin 0.0027 0 0.0031 0 0.0001 0.0002 0.0194 0 0.013 0.0009 0.0021 0.0034 0.0224 0.0001 0.0002 0.0021 0.001 0
Bud 0.0002 0 0.0022 0 0 0 0.0005 0 0.0007 0.0002 0.0004 0.0007 0.0008 0.0017 0.0001 0.0001 0.0003 0
Bud Neck 0.0027 0.0002 0.0006 0.0001 0.0002 0.0014 0.0013 0.0001 0.0011 0.0005 0.0012 0.0023 0.0032 0.0001 0.0003 0.0002 0.0006 0.0004
Bud Periphery 0.0004 0 0.0023 0 0 0.0001 0.0009 0 0.0007 0.0001 0.0007 0.0016 0.0017 0.0002 0.0001 0.0001 0.0007 0
Bud Site 0.0002 0.0004 0.002 0 0 0.0001 0.0023 0.0001 0.0161 0.0014 0.0055 0.0009 0.0022 0.0006 0.0001 0.0001 0.0005 0
Cell Periphery 0.0001 0 0.0001 0 0 0 0.0002 0 0.0002 0 0.0002 0.0002 0.0002 0 0 0 0.0001 0
Cytoplasm 0.0138 0.0039 0.0219 0.0001 0.0047 0.0002 0.0142 0.0042 0.0037 0.003 0.0039 0.0008 0.0026 0.0066 0.0012 0.0006 0.0032 0.0001
Cytoplasmic Foci 0.0004 0.0001 0.0003 0 0 0 0.0343 0.0002 0.0136 0.011 0.0131 0.0044 0.0076 0.0002 0.0001 0.0151 0.001 0
Eisosomes 0 0 0 0 0 0 0.0002 0 0.0001 0 0 0.0001 0.0004 0 0 0 0 0
Endoplasmic Reticulum 0.0034 0.0004 0.0009 0 0.0004 0.0001 0.0086 0.0001 0.0006 0.0009 0.001 0.0006 0.0043 0.0006 0.0004 0.0005 0.0024 0
Endosome 0.0059 0.0012 0.0012 0 0.0003 0.0001 0.0393 0.0003 0.009 0.0268 0.0165 0.0031 0.0099 0.0002 0.0009 0.0141 0.0085 0
Golgi 0.0005 0 0.0002 0 0 0 0.0054 0 0.0091 0.01 0.0069 0.0016 0.0034 0 0 0.0101 0.0003 0
Lipid Particles 0.0003 0.0001 0.0001 0 0 0 0.0119 0 0.0054 0.0087 0.015 0.0012 0.0018 0 0.0001 0.0146 0.0012 0
Mitochondria 0.0015 0.0002 0.0015 0.0001 0.0006 0.0001 0.0031 0.0001 0.005 0.0021 0.0027 0.0056 0.0066 0.0012 0.0003 0.001 0.0063 0
None 0.001 0.0036 0.0005 0 0.0007 0.0001 0.0068 0.0005 0.0011 0.0009 0.0012 0.0002 0.004 0.0013 0.0002 0.0001 0.0017 0
Nuclear Periphery 0.0585 0.0077 0.0131 0.0011 0.0105 0.002 0.0485 0.0034 0.0062 0.0051 0.0069 0.0054 0.0093 0.0072 0.0026 0.0019 0.0141 0.0003
Nucleolus 0.0044 0.012 0.0053 0.0052 0.008 0.0191 0.0102 0.0067 0.0077 0.0062 0.0135 0.0125 0.0085 0.0085 0.0078 0.0087 0.0126 0.0117
Nucleus 0.8966 0.9527 0.9297 0.9928 0.9692 0.9742 0.736 0.9715 0.8919 0.9085 0.8909 0.949 0.9018 0.9656 0.9711 0.9252 0.9363 0.9746
Peroxisomes 0.0001 0 0.0001 0 0 0 0.0067 0 0.0064 0.0037 0.0068 0.0021 0.001 0 0 0.0044 0.0008 0
Punctate Nuclear 0.0031 0.014 0.0135 0.0005 0.0045 0.0018 0.0381 0.0119 0.0073 0.0076 0.0084 0.0027 0.0054 0.0052 0.0138 0.0007 0.0029 0.0127
Vacuole 0.0022 0.0027 0.0011 0 0.0003 0.0003 0.0088 0.0008 0.0009 0.0017 0.0024 0.0012 0.0016 0.0006 0.0005 0.0002 0.0034 0.0001
Vacuole Periphery 0.0021 0.0007 0.0005 0 0.0003 0.0001 0.0032 0.0001 0.0003 0.0005 0.0007 0.0005 0.0015 0.0002 0.0001 0.0002 0.0019 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 16.5135 18.4526 20.9124 20.9221 14.8414 14.6289 24.8483 24.8416 17.2098 19.7138
Translational Efficiency 0.325 0.3353 0.2065 0.1954 0.2467 0.3071 0.2452 0.2059 0.319 0.2046

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2307 904 956 668 2330 1450 1292 210 4637 2354 2248 878

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 705.75 841.22 927.24 863.67 721.20 779.04 877.41 942.15 713.51 802.92 898.60 882.44
Standard Deviation 77.28 111.78 106.95 125.65 95.20 132.30 121.94 131.31 87.09 128.43 118.39 131.37
Intensity Change Log 2 — 0.253326 0.393786 0.291323 — 0.111298 0.282852 0.385557 — 0.183291 0.338784 0.339719

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000043 0.000209 0.000553 0.000604 0.000075 0.000362 0.000381 0.001287 0.000059 0.000303 0.000454 0.000767
Bud Neck 0.001580 0.003902 0.010747 0.008090 0.002491 0.003718 0.005551 0.018397 0.002038 0.003789 0.007761 0.010556
Bud Site 0.000782 0.001451 0.002213 0.005574 0.000312 0.001735 0.001006 0.022852 0.000546 0.001626 0.001520 0.009707
Cell Periphery 0.000078 0.000071 0.000066 0.000232 0.000132 0.000975 0.000199 0.000414 0.000105 0.000628 0.000142 0.000275
Cytoplasm 0.022282 0.004551 0.002021 0.063583 0.017516 0.011754 0.015766 0.019999 0.019887 0.008988 0.009921 0.053159
Cytoplasmic Foci 0.001427 0.000977 0.000049 0.004030 0.000959 0.001787 0.001207 0.005330 0.001192 0.001476 0.000715 0.004341
Eisosomes 0.000007 0.000014 0.000021 0.000035 0.000009 0.002805 0.000033 0.000053 0.000008 0.001733 0.000028 0.000039
Endoplasmic Reticulum 0.001099 0.003685 0.005609 0.004963 0.001847 0.003410 0.004142 0.007370 0.001475 0.003515 0.004766 0.005539
Endosome 0.000194 0.000411 0.000259 0.007020 0.000191 0.000523 0.000405 0.024435 0.000193 0.000480 0.000343 0.011185
Golgi 0.000100 0.000180 0.000107 0.005744 0.000059 0.000471 0.000079 0.001843 0.000079 0.000359 0.000091 0.004811
Lipid Particles 0.000480 0.000419 0.000104 0.000766 0.000311 0.001574 0.000245 0.000735 0.000395 0.001131 0.000185 0.000759
Mitochondria 0.001719 0.001658 0.000968 0.005343 0.000952 0.002047 0.001049 0.005140 0.001333 0.001898 0.001015 0.005294
Mitotic Spindle 0.000830 0.003305 0.001512 0.018788 0.001160 0.003487 0.001832 0.030553 0.000996 0.003417 0.001696 0.021602
None 0.006711 0.004551 0.001448 0.019518 0.008675 0.018032 0.013941 0.012991 0.007698 0.012855 0.008628 0.017956
Nuclear Periphery 0.000636 0.000831 0.000539 0.001532 0.000832 0.001291 0.000524 0.001128 0.000735 0.001114 0.000531 0.001436
Nuclear Periphery Foci 0.000178 0.000327 0.000091 0.001527 0.000174 0.000755 0.000099 0.000533 0.000176 0.000590 0.000096 0.001289
Nucleolus 0.003019 0.005033 0.002660 0.003358 0.004618 0.003143 0.003225 0.001611 0.003822 0.003869 0.002984 0.002940
Nucleus 0.957790 0.966791 0.969079 0.828655 0.958913 0.935406 0.947644 0.821294 0.958354 0.947459 0.956759 0.826895
Peroxisomes 0.000431 0.000497 0.000116 0.000762 0.000217 0.004526 0.000103 0.001953 0.000324 0.002979 0.000108 0.001047
Vacuole 0.000501 0.000942 0.001671 0.016434 0.000463 0.001985 0.002059 0.020688 0.000482 0.001584 0.001894 0.017452
Vacuole Periphery 0.000112 0.000194 0.000168 0.003440 0.000095 0.000214 0.000511 0.001395 0.000104 0.000206 0.000365 0.002951

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.00 -15.58 -11.58 -9.29 -5.04 -1.56 -13.29 -10.12 -5.03 -7.03 -2.13 -20.35 -14.72 -6.53 -8.12
Bud Neck -4.19 -8.11 -9.30 -7.03 -0.72 -2.49 -8.06 -6.94 -6.27 -4.55 -4.70 -11.25 -11.32 -9.34 -3.98
Bud Site -0.83 -1.83 -5.15 -3.87 -3.06 -2.25 -3.98 -2.57 -2.19 -2.30 -2.13 -3.10 -5.39 -4.25 -4.25
Cell Periphery 0.48 0.97 -4.31 -4.22 -4.58 -3.89 -1.62 -1.24 3.44 -0.43 -3.91 -1.55 -3.35 3.26 -2.11
Cytoplasm 8.59 11.82 -5.44 -9.68 -10.68 2.82 1.84 0.58 -1.36 -0.70 7.19 7.90 -5.67 -8.81 -9.02
Cytoplasmic Foci 0.90 4.82 -1.79 -2.34 -4.65 -1.58 0.18 -0.93 0.10 -0.98 -0.75 3.10 -2.35 -1.57 -3.86
Eisosomes -5.27 -14.18 -12.19 -9.96 -7.73 -3.82 -11.78 -8.41 3.74 -4.35 -3.82 -16.17 -14.56 3.71 -7.46
Endoplasmic Reticulum -10.92 -17.97 -13.22 -8.02 -4.18 -4.93 -9.85 -8.93 -7.36 -5.64 -9.63 -17.75 -15.48 -10.77 -6.82
Endosome -2.08 -1.43 -3.36 -3.13 -3.28 -2.29 -2.73 -1.77 -1.68 -1.71 -2.93 -3.03 -3.54 -3.28 -3.40
Golgi -1.00 0.00 -1.61 -1.56 -1.61 -3.20 -0.54 -1.98 -0.37 -1.91 -3.26 -0.21 -1.73 -1.48 -1.73
Lipid Particles 0.30 2.12 -1.67 -2.31 -5.05 -3.31 0.58 -3.18 1.62 -3.64 -2.88 2.05 -3.13 0.94 -5.54
Mitochondria 0.04 1.24 -1.55 -1.50 -2.28 -1.55 -0.51 -2.70 -0.81 -2.51 -1.03 0.79 -2.29 -1.53 -2.66
Mitotic Spindle -1.78 -0.65 -5.05 -4.14 -4.79 -1.69 -1.46 -3.35 -3.16 -3.23 -2.48 -1.63 -5.89 -5.20 -5.58
None 1.54 6.83 -2.78 -3.47 -5.57 -3.10 -1.47 0.34 2.99 1.45 -2.65 0.37 -2.30 0.48 -2.29
Nuclear Periphery -1.28 0.17 -8.89 -6.86 -9.57 -0.91 0.92 -5.73 -2.58 -6.21 -1.25 0.67 -10.37 -4.50 -11.18
Nuclear Periphery Foci -1.10 0.81 -2.50 -2.21 -2.60 -1.63 0.66 -2.04 -0.82 -2.09 -1.83 0.99 -3.00 -1.85 -3.08
Nucleolus -2.02 0.75 -1.58 1.04 -2.05 2.15 2.23 3.23 1.04 1.46 -0.02 2.20 0.52 0.44 -1.27
Nucleus -1.66 -2.26 12.55 12.77 13.43 3.98 3.01 7.29 5.85 6.58 2.81 1.27 14.65 12.42 14.04
Peroxisomes -0.39 1.41 -0.26 0.19 -2.74 -3.31 1.61 -1.16 2.86 -1.52 -3.29 1.90 -1.17 3.02 -3.12
Vacuole -2.54 -6.86 -8.28 -8.09 -7.77 -3.42 -5.44 -5.14 -4.96 -4.86 -4.06 -7.56 -9.60 -9.20 -8.93
Vacuole Periphery -1.58 -0.73 -2.43 -2.28 -2.34 -2.40 -1.00 -1.72 -1.18 -0.20 -2.79 -1.10 -2.63 -2.39 -2.04
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transcriptional activator; binds specific gene recruitment sequences and is required for DNA zip code-mediated targeting of genes to nuclear periphery; regulates proline utilization genes, constitutively binds PUT1 and PUT2 promoters as a dimer, undergoes conformational change to form active state; binds other promoters only under activating conditions; differentially phosphorylated in presence of different nitrogen sources; has a Zn(2)-Cys(6) binuclear cluster domain
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Put3

Put3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Put3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available