Standard name
Human Ortholog
Description Protein of unknown function; gene expression increases in cultures shifted to a lower temperature; protein abundance increases in response to DNA replication stress
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.06 0 0 0 0.1 0.07 0.09 0.07 0.06 0.07 0.06 0.08 0.15 0.18 0.09 0.08 0.11 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.08 0 0 0.28 0.11 0.09 0.09 0.58 0.19 0.3 0.41 0 0 0 0.05 0 0 0 0 0 0 0 0
Nucleus 0.9 0.89 0.96 0.96 0.85 0.8 0.82 0.81 0.67 0.8 0.74 0.65 0.89 0.78 0.74 0.81 0.76 0.73 0.89 0.87 0.92 0.79 0.7 0.68
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.09 0 0 0 0 0.05 0.06 0.05 0 0.06 0.05 0.09 0 0.07 0.06 0.11 0.16 0.16 0.05 0.05 0 0.09 0.15 0.19
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 1 5 0 2 0 2 4 1 5 0 0 0 0 0 0 1 2 0 8 6 6
Bud Neck 0 0 0 0 1 0 0 2 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0
Bud Site 0 0 0 0 2 2 1 1 6 3 1 21 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 11 24 2 2 4 22 13 23 19 12 19 24 29 75 92 28 28 33 3 8 1 9 9 5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 15 20 0 1 0 0 0 1
Endosome 0 0 0 1 0 1 1 1 0 0 0 1 3 5 15 1 10 6 4 2 0 1 2 4
Golgi 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1
Mitochondria 3 35 0 4 43 23 16 22 151 37 81 152 3 1 4 14 11 5 0 6 0 6 6 8
Nucleus 260 367 121 145 130 170 153 198 173 159 203 245 333 394 367 247 262 221 271 378 138 279 244 275
Nuclear Periphery 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 1 2
Nucleolus 1 1 0 1 2 2 5 1 4 1 3 16 1 0 5 0 2 0 0 0 0 3 8 12
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 1 0 3 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 1 1 1 1 1 1 0 0 2 1 1 2 4 3 1 0 4 9 4
Vac/Vac Membrane 26 18 3 2 6 11 12 13 10 11 15 33 10 36 29 33 56 47 13 23 5 30 50 76
Unique Cell Count 289 414 126 151 153 212 187 244 259 198 274 375 375 502 499 306 346 302 303 435 151 351 348 406
Labelled Cell Count 302 445 126 156 193 232 205 262 366 228 324 498 381 514 518 338 386 336 303 435 151 351 348 406


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.8 5.5 6.9 6.3 4.7 5.7 5.8 5.7 4.6 5.1 5.1 4.8 6.9 6.6 6.3 6.2 7.8 7.6 7.1 7.4 7.4
Std Deviation (1e-4) 1.3 0.9 1.0 0.9 1.2 1.4 1.3 1.2 1.0 1.0 1.0 0.9 1.3 1.3 1.5 1.6 1.8 2.0 1.7 1.8 1.4
Intensity Change (Log2) – – – -0.14 -0.55 -0.27 -0.26 -0.27 -0.59 -0.42 -0.43 -0.51 -0.01 -0.07 -0.14 -0.14 0.19 0.15 0.05 0.1 0.11

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 3.0 2.2 2.8 2.3 1.9 2.2 2.1 2.5 4.1 4.7 2.8 2.6 3.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3.0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 3.8 3.4 3.5 0 5.2 6.8 0 0 0 0 0 0 0
Nucleus 0 -3.1 -4.1 -3.7 -3.9 -6.3 -4.0 -5.2 -6.7 -2.4 -4.6 -5.5 -4.1 -5.0 -5.4
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 1.3 1.6 1.3 0 1.4 1.4 2.4 0 2.0 1.6 2.9 4.0 3.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.7334 6.8496 6.7592 6.857 6.3277 6.9998 8.4433 9.5338 8.2776 8.899 8.0782 8.6599 4.5933 5.1024 4.7825 4.8911 4.7421 5.0634
Actin 0.0313 0 0.0059 0.0001 0.0177 0.0006 0.0069 0 0.0045 0 0.0011 0.0001 0.0166 0 0.0055 0.0006 0.0002 0
Bud 0.0005 0 0.0005 0 0.001 0 0.0002 0 0.0001 0 0.0001 0 0.0003 0.0011 0.0002 0.0001 0 0
Bud Neck 0.0027 0.0001 0.001 0.0001 0.0022 0.0007 0.0005 0.0001 0.0009 0.0001 0.0148 0.0004 0.001 0.0001 0.0002 0.0003 0.0003 0.0008
Bud Periphery 0.0008 0 0.001 0 0.003 0.0001 0.0007 0 0.0006 0 0.0002 0 0.0008 0.0002 0.0001 0.0004 0.0001 0
Bud Site 0.0027 0.0001 0.005 0 0.0018 0.0001 0.0007 0.0004 0.0002 0 0.0003 0 0.0006 0.0001 0.0045 0.0001 0.0002 0
Cell Periphery 0.0002 0 0.0004 0 0.0012 0 0.0002 0 0.0001 0 0.0001 0 0.0002 0 0 0.0001 0 0
Cytoplasm 0.0071 0.0003 0.0039 0.0001 0.003 0.0003 0.0011 0.0005 0.0004 0.0001 0.0003 0.0001 0.0021 0.0004 0.0018 0.0002 0.0005 0.0001
Cytoplasmic Foci 0.0066 0 0.002 0.0019 0.0074 0.0002 0.0014 0 0.0006 0 0.0027 0.0009 0.0034 0 0.0024 0.0003 0.0073 0
Eisosomes 0.0006 0 0 0 0.0004 0 0.0001 0 0 0 0 0 0.0001 0 0 0 0 0
Endoplasmic Reticulum 0.0036 0 0.0024 0.0003 0.0054 0.0006 0.0034 0 0.0008 0 0.0002 0 0.0071 0 0.0007 0.0011 0.0002 0
Endosome 0.0093 0 0.0053 0.0154 0.0109 0.0008 0.0103 0.0002 0.0018 0 0.0125 0.0007 0.011 0 0.0058 0.0024 0.0085 0
Golgi 0.0032 0 0.0025 0.0076 0.005 0.0002 0.0039 0 0.001 0 0.01 0.0002 0.0045 0 0.0056 0.0007 0.0099 0
Lipid Particles 0.0041 0 0.0025 0.0269 0.0174 0.0007 0.0085 0 0.0015 0 0.0006 0.0009 0.0053 0 0.0009 0.0087 0.0067 0
Mitochondria 0.007 0.0001 0.0045 0.0009 0.0374 0.0004 0.0048 0 0.0025 0.0001 0.002 0.0001 0.0035 0.0002 0.0021 0.0029 0.0034 0.0001
None 0.0038 0 0.0052 0 0.0048 0.0001 0.0008 0 0.0001 0 0.0001 0 0.0014 0.0001 0.0011 0.0002 0.0002 0
Nuclear Periphery 0.0254 0.002 0.009 0.0023 0.0104 0.002 0.0181 0.002 0.0034 0.0014 0.0008 0.0003 0.0263 0.0014 0.0068 0.0257 0.0028 0.0007
Nucleolus 0.0068 0.0068 0.0058 0.0012 0.009 0.014 0.0061 0.0052 0.0057 0.0108 0.0088 0.0091 0.0086 0.0056 0.0023 0.0065 0.0168 0.0128
Nucleus 0.8606 0.9896 0.9333 0.94 0.8511 0.9781 0.9233 0.9877 0.9729 0.987 0.9429 0.9848 0.8955 0.9895 0.9561 0.9444 0.9245 0.9827
Peroxisomes 0.007 0 0.0034 0.0002 0.0026 0.0001 0.0007 0 0.0003 0 0.0004 0.0011 0.0015 0 0.0009 0.0002 0.0168 0
Punctate Nuclear 0.0136 0.0008 0.0033 0.0004 0.0033 0.0008 0.0028 0.0005 0.0014 0.0001 0.0013 0.0011 0.0068 0.0011 0.0025 0.0014 0.0007 0.0025
Vacuole 0.0016 0.0001 0.0021 0.001 0.0031 0.0002 0.004 0.0033 0.0006 0.0003 0.0006 0 0.0018 0.0001 0.0002 0.0014 0.0006 0.0001
Vacuole Periphery 0.0016 0 0.0009 0.0014 0.0017 0.0001 0.0016 0.0001 0.0005 0.0002 0.0003 0 0.0017 0 0.0002 0.0022 0.0003 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 19.7678 51.4072 30.1992 27.9849 24.8532 21.553 30.3204 31.0618 27.8499 19.7452
Translational Efficiency 0.9823 0.6996 1.0845 1.0209 0.9899 0.7004 1.2461 1.095 0.9348 1.2426

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1866 1060 521 1548 2162 1735 137 1129 4028 2795 658 2677

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 779.32 829.54 1032.15 1096.78 713.63 900.57 1128.24 1082.92 744.06 873.63 1052.16 1090.93
Standard Deviation 106.13 155.55 147.91 221.60 106.29 117.43 136.79 164.15 111.15 137.57 150.80 199.52
Intensity Change Log 2 — 0.090096 0.405365 0.492986 — 0.335662 0.660826 0.601678 — 0.212698 0.533126 0.545964

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000095 0.000755 0.000578 0.000929 0.000075 0.000748 0.001195 0.001618 0.000084 0.000750 0.000706 0.001219
Bud Neck 0.001750 0.006009 0.010090 0.033381 0.003013 0.006077 0.005889 0.025302 0.002428 0.006051 0.009215 0.029974
Bud Site 0.000409 0.003191 0.000861 0.006716 0.001021 0.002697 0.000988 0.006042 0.000737 0.002884 0.000888 0.006431
Cell Periphery 0.000150 0.000297 0.000055 0.000119 0.000156 0.000165 0.000054 0.000178 0.000153 0.000215 0.000055 0.000144
Cytoplasm 0.036983 0.028523 0.000715 0.007712 0.045270 0.012534 0.000980 0.009218 0.041431 0.018598 0.000770 0.008347
Cytoplasmic Foci 0.002848 0.003201 0.000013 0.001772 0.002224 0.002856 0.000051 0.001798 0.002513 0.002987 0.000021 0.001783
Eisosomes 0.000011 0.000024 0.000024 0.000024 0.000009 0.000017 0.000052 0.000031 0.000010 0.000020 0.000030 0.000027
Endoplasmic Reticulum 0.002204 0.006912 0.004124 0.004643 0.001645 0.004211 0.007799 0.006401 0.001904 0.005235 0.004889 0.005384
Endosome 0.000526 0.002381 0.000114 0.004754 0.000364 0.001369 0.000159 0.002859 0.000439 0.001753 0.000124 0.003955
Golgi 0.000302 0.001869 0.000031 0.003061 0.000058 0.001008 0.000052 0.004105 0.000171 0.001335 0.000035 0.003501
Lipid Particles 0.001518 0.000676 0.000043 0.000171 0.000338 0.001156 0.000168 0.000359 0.000885 0.000974 0.000069 0.000250
Mitochondria 0.002460 0.002670 0.000964 0.005832 0.000660 0.003036 0.001039 0.005982 0.001494 0.002897 0.000980 0.005895
Mitotic Spindle 0.000870 0.002889 0.000590 0.047888 0.000321 0.003015 0.000084 0.017584 0.000575 0.002967 0.000484 0.035108
None 0.007947 0.017882 0.000960 0.003729 0.012402 0.005203 0.000684 0.006515 0.010338 0.010011 0.000903 0.004904
Nuclear Periphery 0.000689 0.000653 0.000262 0.004142 0.000597 0.001160 0.000305 0.002440 0.000640 0.000968 0.000271 0.003424
Nuclear Periphery Foci 0.000759 0.001146 0.000024 0.003488 0.000194 0.000551 0.000121 0.001879 0.000455 0.000776 0.000044 0.002810
Nucleolus 0.001882 0.006359 0.001659 0.002636 0.002426 0.004146 0.002138 0.002808 0.002174 0.004986 0.001759 0.002709
Nucleus 0.936930 0.908807 0.977591 0.849435 0.927408 0.945948 0.974949 0.892755 0.931819 0.931863 0.977041 0.867705
Peroxisomes 0.000237 0.001510 0.000103 0.000245 0.000222 0.001419 0.000237 0.000564 0.000229 0.001454 0.000131 0.000379
Vacuole 0.001285 0.003264 0.001139 0.011474 0.001301 0.002250 0.002983 0.009069 0.001293 0.002634 0.001523 0.010460
Vacuole Periphery 0.000146 0.000983 0.000062 0.007852 0.000296 0.000433 0.000075 0.002491 0.000227 0.000641 0.000065 0.005591

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.55 -12.48 -7.88 -1.34 -3.38 -1.76 -10.74 -6.74 -1.87 0.03 -2.71 -15.89 -10.14 -1.92 -3.58
Bud Neck -6.42 -9.93 -15.72 -12.94 -10.14 -3.59 -5.04 -14.03 -11.47 -10.53 -6.34 -10.20 -20.63 -16.96 -13.22
Bud Site -3.31 -3.69 -8.37 -2.18 -7.36 -1.92 -1.71 -5.63 -2.36 -4.50 -3.48 -1.89 -9.64 -3.32 -9.09
Cell Periphery -2.96 3.50 1.63 4.45 -4.76 -0.39 4.62 0.34 0.68 -3.81 -2.54 5.97 1.77 4.29 -6.19
Cytoplasm 2.09 15.24 11.25 6.42 -8.98 11.60 11.17 13.14 1.86 -2.10 10.07 21.87 17.41 6.35 -8.88
Cytoplasmic Foci -0.30 5.64 3.95 3.77 -3.69 -0.85 5.34 2.75 3.07 -2.49 -0.76 7.87 4.85 4.77 -4.42
Eisosomes -6.35 -9.95 -12.59 -1.71 -1.96 -5.36 -11.34 -11.84 -7.24 4.56 -8.13 -14.55 -17.39 -7.07 0.06
Endoplasmic Reticulum -11.29 -3.68 -10.33 3.34 -1.88 -9.11 -9.15 -13.23 -6.59 1.42 -14.02 -7.07 -17.05 -3.13 -2.13
Endosome -3.27 2.24 -3.28 0.54 -4.57 -3.40 1.76 -3.97 -0.70 -4.30 -4.57 3.26 -4.92 -0.32 -6.21
Golgi -2.19 1.90 -2.56 0.76 -3.66 -3.12 -1.39 -2.12 -0.97 -2.09 -3.51 1.93 -3.21 -0.40 -3.58
Lipid Particles 1.58 2.87 2.57 4.23 -7.18 -3.12 1.01 -0.97 2.79 -2.45 -0.41 3.30 2.39 4.10 -6.54
Mitochondria -0.18 1.49 -2.07 -2.29 -7.13 -3.29 -3.26 -4.36 -1.36 -3.73 -2.13 0.81 -4.91 -2.42 -7.22
Mitotic Spindle -1.80 -0.79 -8.58 -7.68 -7.23 -2.87 -0.35 -6.30 -5.11 -6.26 -3.28 -0.93 -10.61 -9.24 -8.50
None -3.87 8.28 4.00 5.59 -8.62 4.95 9.78 5.33 0.35 -4.69 0.28 12.66 6.92 4.84 -8.58
Nuclear Periphery 0.39 5.59 -5.38 -5.44 -6.15 -2.80 1.11 -8.66 -5.51 -8.91 -2.55 5.89 -8.27 -6.76 -9.21
Nuclear Periphery Foci -0.90 1.95 -1.27 -0.59 -3.00 -2.24 -0.61 -2.65 -1.58 -2.25 -1.49 2.10 -2.55 -1.65 -3.94
Nucleolus -5.62 0.78 -4.00 3.03 -4.42 -3.13 0.46 -2.51 0.06 -2.55 -6.19 1.53 -4.40 1.98 -5.19
Nucleus 3.99 -8.40 8.78 3.71 15.28 -3.44 -6.26 5.54 7.90 9.82 0.14 -11.81 10.20 9.18 18.79
Peroxisomes -1.88 2.11 0.64 1.96 -2.23 -2.86 0.02 -0.55 2.70 -0.93 -3.38 1.34 -0.13 3.41 -2.47
Vacuole -3.80 0.31 -8.85 -6.61 -8.78 -2.43 -3.64 -7.38 -6.79 -5.10 -4.31 -1.95 -11.38 -9.77 -10.45
Vacuole Periphery -2.19 1.31 -3.84 -2.54 -3.95 -0.71 1.15 -2.09 -1.89 -2.74 -2.28 1.56 -4.29 -3.38 -4.69
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; gene expression increases in cultures shifted to a lower temperature; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages nucleus (95%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Lot5

Lot5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Lot5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available