Standard name
Human Ortholog
Description AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis; mutations in human PEX1 can lead to severe peroxisomal disorders and early death
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.2 0.1 0.11 0.13 0.08 0.05 0 0.06 0 – 0 0 0.16 0.21 0.17 0 0 0 0.05 0.15 0.06 0.1 0.21 0.17
Bud 0.05 0.06 0.14 0.14 0.25 0.19 0.12 0.12 0.14 – 0.12 0.1 0.1 0.13 0.15 0.06 0.06 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0.06 0.06 0 0.06 0.08 0 0.05 – 0.06 0 0 0 0 0.05 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0.05 0.05 0 – 0 0 0 0.05 0.07 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.14 0.05 0 0 0.1 0.07 0.06 0.09 0 – 0 0 0.1 0.23 0.24 0.18 0.19 0.16 0.06 0.11 0.18 0.18 0.16 0.08
Golgi 0.11 0.06 0 0 0 0 0 0 0 – 0 0 0.13 0 0 0 0.05 0.05 0 0.06 0 0 0 0
Mitochondria 0.52 0.69 0.84 0.82 0.48 0.7 0.65 0.57 0.84 – 0.83 0.89 0.5 0.14 0.36 0.09 0.1 0.09 0 0.06 0 0.05 0 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0
Peroxisomes 0.53 0.36 0.27 0.33 0.53 0.28 0.3 0.27 0.15 – 0.12 0.12 0.49 0.54 0.31 0.51 0.54 0.38 0.79 0.54 0.59 0.5 0.47 0.64
SpindlePole 0.09 0.06 0.08 0.06 0.16 0.11 0.09 0.14 0.08 – 0.05 0.05 0.07 0.22 0.13 0.38 0.39 0.45 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 35 18 15 32 28 19 18 38 12 – 12 12 21 56 61 17 5 25 9 31 8 12 50 64
Bud 9 11 18 35 85 75 62 74 48 – 41 40 13 34 51 31 22 38 1 3 2 3 3 1
Bud Neck 0 0 0 1 1 1 0 0 0 – 0 0 0 0 0 0 6 2 0 3 3 2 5 3
Bud Site 4 2 8 14 10 22 39 22 17 – 21 11 4 3 11 24 11 31 – – – – – –
Cell Periphery 1 5 1 2 1 1 5 5 2 – 1 2 1 8 4 2 0 2 0 0 0 0 0 0
Cytoplasm 1 6 2 9 12 13 26 29 11 – 13 9 5 14 25 21 15 30 0 1 1 1 1 0
Endoplasmic Reticulum 1 2 3 6 3 5 6 16 9 – 7 10 0 1 9 4 3 8 0 0 0 0 0 1
Endosome 25 9 0 5 35 27 30 56 6 – 2 1 13 62 85 93 65 111 12 22 25 23 39 31
Golgi 20 10 2 0 0 0 2 1 0 – 0 1 17 10 11 22 19 36 7 12 5 4 3 13
Mitochondria 91 124 110 199 164 276 328 346 288 – 276 372 66 38 126 48 35 62 3 12 3 6 8 13
Nucleus 0 0 0 0 0 2 2 1 1 – 2 4 0 0 1 3 3 8 0 0 0 0 0 0
Nuclear Periphery 5 6 0 1 1 5 12 3 3 – 10 6 3 1 0 11 4 14 0 0 0 0 0 1
Nucleolus 4 8 3 2 6 9 8 21 2 – 1 6 1 4 5 28 17 27 0 0 0 0 0 0
Peroxisomes 93 65 36 81 184 112 151 165 50 – 41 49 65 145 109 260 190 272 151 112 85 63 115 243
SpindlePole 16 10 11 14 55 43 45 84 27 – 18 19 9 60 46 195 138 317 4 4 5 5 10 5
Vac/Vac Membrane 1 5 0 0 2 0 2 4 0 – 0 4 1 2 4 10 6 10 0 1 1 0 2 0
Unique Cell Count 175 181 131 243 345 396 507 605 344 331 419 133 268 349 514 350 708 192 207 145 126 245 383
Labelled Cell Count 306 281 209 401 587 610 736 865 476 445 546 219 438 548 769 539 993 192 207 145 126 245 383


Peroxisomes

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.6 6.6 4.9 4.8 5.3 4.9 4.7 4.7 4.2 – 4.1 3.8 6.6 6.9 6.0 7.2 8.0 8.2 6.9 6.3 7.0
Std Deviation (1e-4) 1.1 0.9 0.7 1.0 1.2 1.2 1.1 1.1 0.9 – 0.8 0.8 1.0 1.1 1.0 1.5 1.9 1.8 1.7 1.3 1.2
Intensity Change (Log2) – – – -0.03 0.11 0.0 -0.07 -0.07 -0.23 – -0.28 -0.38 0.43 0.48 0.29 0.55 0.69 0.73 0.49 0.35 0.51

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – 2.6 1.4 0 0 – – – – -1.0 -0.3 0.2 -3.0 -2.6 -3.5
Bud Neck – 0 0 0 0 – – – – 0 0 0 0 0 0
Bud Site – 0 -0.2 0 0 – – – – -1.2 0 -1.5 -0.7 -1.5 -0.9
Cell Periphery – 0 0 0 0 – – – – 0 0 0 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – 0 0 0 0 – – – – 0 0 0 0 0 0
Endosome – 3.8 3.1 0 0 – – – – 3.7 6.0 6.2 5.3 5.3 4.9
Golgi – 0 0 0 0 – – – – 3.5 0 0 0 1.9 1.8
Mitochondria – -7.2 -3.2 0 0 – – – – -5.9 -13.6 -9.3 -17.7 -15.7 -19.6
Nuclear Periphery – 0 0 0 0 – – – – 0 0 0 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – 0 0 0 0 – – – – 0 0 0 1.5 1.3 0
Peroxisomes – 5.1 0.2 0 0 – – – – 3.6 5.0 0.8 4.7 5.2 2.4
SpindlePole – 2.1 0.8 0 0 – – – – -0.5 3.4 1.4 6.5 6.6 7.8
Vac – – – – – – – – – – – – – – –
Cortical Patches – -1.1 -2.7 0 0 – – – – 1.0 2.3 1.6 -3.8 -4.9 -3.9
Cytoplasm – 0 0 1.8 1.7 – – – – 0 1.8 2.4 0 0 0
Nucleus – 0 0 0 0 – – – – 0 0 0 0 0 0
Vacuole – 0 0 0 0 – – – – 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.0664 3.0847 2.9866 2.629 3.087 3.0596 3.1247 3.3334 3.2646 3.41 3.3518 3.4529 1.1654 2.0608 1.6187 1.4319 0.9427 1.6088
Actin 0.0639 0.0655 0.0957 0.0251 0.0548 0.0608 0.07 0.1013 0.1364 0.0466 0.0748 0.0833 0.066 0.0947 0.1017 0.0113 0.0193 0.0847
Bud 0.0005 0.0003 0.0005 0.0001 0.0001 0.0001 0.0006 0.0009 0.0009 0.0007 0.0013 0.0003 0.0002 0.0004 0.0005 0.0003 0.0001 0.0002
Bud Neck 0.0058 0.0008 0.0024 0.0015 0.0052 0.0094 0.0017 0.0014 0.0024 0.0014 0.0033 0.001 0.0102 0.003 0.008 0.0667 0.0013 0.014
Bud Periphery 0.0009 0.0003 0.0007 0.0001 0.0001 0.0002 0.0007 0.0008 0.0008 0.0008 0.001 0.0003 0.0003 0.0003 0.0006 0.0004 0 0.0002
Bud Site 0.0089 0.0066 0.0051 0.0004 0.0038 0.0004 0.0047 0.0112 0.0067 0.0018 0.0088 0.0006 0.0116 0.0422 0.0191 0.0018 0.0002 0.001
Cell Periphery 0.0006 0 0.0001 0 0.0001 0 0.0001 0.0001 0.0001 0 0.0001 0 0.0005 0.0001 0.0001 0.0002 0 0
Cytoplasm 0.0158 0.0042 0.0038 0.0005 0.0005 0.0004 0.0054 0.0141 0.0008 0.0007 0.0013 0.0005 0.0021 0.0056 0.001 0.0005 0.0004 0.0005
Cytoplasmic Foci 0.1097 0.1788 0.1198 0.1686 0.0979 0.1119 0.1225 0.1863 0.1165 0.1244 0.1673 0.1075 0.1109 0.1498 0.1312 0.1516 0.1574 0.1304
Eisosomes 0.0004 0.0001 0.0004 0 0.0004 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0005 0 0 0.0001
Endoplasmic Reticulum 0.0027 0.0001 0.0014 0 0.0005 0.0005 0.001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0002 0.0003 0 0 0
Endosome 0.0474 0.0347 0.0212 0.0129 0.0396 0.014 0.0563 0.0399 0.0252 0.0612 0.0739 0.0544 0.0123 0.0211 0.0171 0.0154 0.0096 0.0095
Golgi 0.0364 0.0488 0.0217 0.0368 0.03 0.0224 0.0756 0.0622 0.0472 0.0968 0.0656 0.076 0.0223 0.0265 0.0268 0.0475 0.0123 0.014
Lipid Particles 0.0868 0.0333 0.0284 0.033 0.0811 0.0475 0.1004 0.0132 0.0224 0.0139 0.0205 0.0648 0.0713 0.0418 0.0308 0.1121 0.0596 0.0509
Mitochondria 0.0061 0.0081 0.0099 0.0023 0.0076 0.0046 0.0183 0.0099 0.025 0.0173 0.0055 0.0188 0.0043 0.0043 0.0172 0.0119 0.0009 0.0016
None 0.0035 0.0004 0.0026 0.0004 0.0001 0.0032 0.0015 0.0002 0.0002 0.0002 0.0002 0.0001 0.0029 0.0016 0.0145 0.0001 0.0001 0.0002
Nuclear Periphery 0.0008 0.0001 0.0022 0.0002 0.0001 0.0006 0.0086 0 0.0001 0 0.0001 0.0001 0.0001 0.0006 0.0033 0 0 0.0002
Nucleolus 0.0002 0.0001 0.0001 0.0001 0 0.0001 0.0007 0.0001 0.0001 0.0001 0.0003 0.0001 0.0028 0.0002 0.0005 0.0001 0.0001 0.0001
Nucleus 0.0003 0.0001 0.0005 0 0 0.0001 0.0053 0.0001 0.0001 0 0.0002 0 0.0002 0.0013 0.0004 0 0 0
Peroxisomes 0.6044 0.6106 0.6788 0.7067 0.6766 0.7153 0.5071 0.5562 0.6127 0.6326 0.571 0.5901 0.6779 0.5822 0.6231 0.5792 0.7362 0.6888
Punctate Nuclear 0.0022 0.0065 0.0039 0.011 0.0009 0.0081 0.0169 0.0015 0.0013 0.0008 0.0012 0.0011 0.003 0.0235 0.0025 0.0005 0.0023 0.0037
Vacuole 0.0018 0.0004 0.0005 0.0001 0.0003 0.0001 0.0014 0.0004 0.0005 0.0003 0.003 0.0005 0.0005 0.0004 0.0004 0.0003 0.0001 0.0001
Vacuole Periphery 0.0009 0.0002 0.0003 0 0.0003 0.0001 0.0009 0.0002 0.0003 0.0002 0.0005 0.0003 0.0001 0.0001 0.0005 0.0001 0 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.6883 11.6526 10.2826 15.8255 10.7342 9.8589 14.807 14.3996 16.4352 15.0402
Translational Efficiency 0.7514 0.5433 0.5979 0.5038 0.5259 0.7074 0.5889 0.5564 0.5054 0.4982

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
804 1381 138 402 1367 1246 1736 142 2171 2627 1874 544

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 702.73 883.06 1066.31 1008.50 707.69 862.18 941.13 1040.91 705.85 873.16 950.35 1016.96
Standard Deviation 88.73 1163.61 158.21 117.58 101.41 114.65 120.38 144.30 96.94 847.42 127.82 125.91
Intensity Change Log 2 — 0.329541 0.601585 0.521169 — 0.284872 0.411276 0.556656 — 0.307301 0.509232 0.539084

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.023913 0.046711 0.200869 0.347990 0.023216 0.059802 0.087128 0.383699 0.023474 0.052920 0.095504 0.357311
Bud Neck 0.002473 0.001510 0.003533 0.001814 0.003885 0.001637 0.002380 0.001450 0.003362 0.001570 0.002465 0.001719
Bud Site 0.006932 0.009132 0.059556 0.028373 0.013379 0.006707 0.022275 0.019459 0.010991 0.007982 0.025020 0.026046
Cell Periphery 0.000147 0.000321 0.000160 0.000142 0.000134 0.000073 0.000088 0.000137 0.000139 0.000203 0.000094 0.000141
Cytoplasm 0.005960 0.004361 0.006723 0.009160 0.007826 0.004017 0.006132 0.005416 0.007135 0.004198 0.006175 0.008183
Cytoplasmic Foci 0.121639 0.101258 0.154462 0.077914 0.137809 0.120817 0.090577 0.067092 0.131821 0.110535 0.095282 0.075089
Eisosomes 0.000102 0.000094 0.000131 0.000208 0.000081 0.000105 0.000097 0.000190 0.000088 0.000099 0.000099 0.000204
Endoplasmic Reticulum 0.000056 0.000132 0.001008 0.000166 0.000074 0.000184 0.000123 0.000930 0.000067 0.000157 0.000188 0.000366
Endosome 0.030985 0.041484 0.039160 0.029697 0.033652 0.057493 0.021036 0.048889 0.032665 0.049077 0.022371 0.034706
Golgi 0.049476 0.045815 0.021198 0.019110 0.037445 0.071462 0.015245 0.019092 0.041900 0.057979 0.015684 0.019105
Lipid Particles 0.016725 0.017401 0.042230 0.005715 0.017144 0.008548 0.016074 0.009996 0.016989 0.013202 0.018000 0.006832
Mitochondria 0.009034 0.004637 0.000227 0.001343 0.004435 0.012113 0.002158 0.003183 0.006138 0.008183 0.002015 0.001823
Mitotic Spindle 0.002217 0.009152 0.059452 0.019746 0.002364 0.008586 0.021301 0.009048 0.002309 0.008884 0.024110 0.016954
None 0.000154 0.000152 0.000023 0.000023 0.000322 0.000021 0.000587 0.000008 0.000260 0.000090 0.000545 0.000019
Nuclear Periphery 0.000012 0.000015 0.000050 0.000021 0.000005 0.000010 0.000022 0.000113 0.000008 0.000013 0.000024 0.000045
Nuclear Periphery Foci 0.000202 0.000206 0.004353 0.000077 0.000231 0.000068 0.000408 0.001224 0.000220 0.000141 0.000699 0.000376
Nucleolus 0.000165 0.000099 0.000034 0.000006 0.000234 0.000071 0.000033 0.000005 0.000208 0.000085 0.000033 0.000006
Nucleus 0.000193 0.000423 0.000188 0.000046 0.000319 0.000213 0.000140 0.000073 0.000272 0.000324 0.000143 0.000053
Peroxisomes 0.729271 0.715550 0.400253 0.455035 0.716902 0.647114 0.712971 0.420266 0.721483 0.683091 0.689943 0.445959
Vacuole 0.000233 0.001149 0.006304 0.003356 0.000442 0.000633 0.001177 0.007885 0.000365 0.000904 0.001554 0.004538
Vacuole Periphery 0.000113 0.000397 0.000086 0.000059 0.000101 0.000327 0.000048 0.001844 0.000106 0.000364 0.000051 0.000525

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.99 -7.36 -17.94 -16.60 -4.92 -8.09 -13.18 -11.63 -10.36 -9.47 -9.37 -15.07 -21.49 -19.42 -16.25
Bud Neck 1.41 -1.55 0.66 -1.02 2.57 2.42 1.78 2.61 0.14 1.48 3.00 1.34 2.46 -0.65 1.55
Bud Site -1.09 -5.26 -4.82 -4.39 2.96 3.26 -3.55 -1.77 -3.27 0.17 1.98 -6.24 -4.48 -5.43 -0.45
Cell Periphery -1.27 -0.87 0.09 1.29 1.06 3.02 2.27 -0.25 -2.94 -2.29 -0.88 2.62 -0.18 0.82 -2.66
Cytoplasm 0.80 -0.64 -1.88 -2.96 -1.24 2.28 0.90 0.15 -0.96 -0.28 2.31 0.53 -1.35 -3.15 -1.84
Cytoplasmic Foci 2.90 -2.11 4.63 2.77 4.74 2.79 8.32 6.65 4.99 2.21 4.68 7.51 8.33 5.38 2.84
Eisosomes 0.59 -2.17 -5.11 -5.78 -3.58 -2.74 -2.26 -4.81 -3.72 -4.17 -1.49 -1.68 -7.37 -6.71 -6.80
Endoplasmic Reticulum -1.23 -4.28 -4.19 -0.76 3.76 -1.66 -2.31 -1.78 -1.53 -1.65 -1.97 -4.86 -2.42 -1.62 -1.30
Endosome -2.85 -1.16 0.14 2.36 1.16 -6.08 4.72 -1.55 0.85 -2.86 -6.18 4.52 -0.59 3.17 -3.05
Golgi 0.91 6.35 6.49 6.85 0.43 -8.94 10.62 3.72 9.21 -0.70 -6.11 13.62 7.18 11.73 -1.09
Lipid Particles -0.24 -2.51 4.05 4.71 3.61 3.45 0.40 1.80 -0.51 1.65 1.89 -0.43 4.73 3.43 5.13
Mitochondria 2.23 4.74 3.95 3.68 -1.77 -3.86 2.20 0.51 2.96 -0.36 -1.59 4.15 3.62 5.33 0.27
Mitotic Spindle -4.42 -5.32 -4.35 -2.42 3.42 -4.32 -9.25 -2.07 -0.92 1.35 -6.15 -10.57 -4.81 -2.67 1.57
None -0.03 1.72 1.70 1.41 -0.06 1.58 -0.41 1.64 3.43 1.04 1.28 -0.51 1.93 1.44 1.02
Nuclear Periphery -0.38 -3.24 -0.96 -0.82 1.97 -2.64 -6.26 -1.16 -1.11 -0.97 -1.33 -4.52 -1.55 -1.37 -0.88
Nuclear Periphery Foci -0.59 -1.77 1.08 1.34 1.79 2.22 -1.71 -1.83 -2.13 -1.49 0.41 -2.31 -1.21 -1.38 1.47
Nucleolus 0.65 1.72 2.17 1.39 2.23 1.15 1.77 2.06 1.15 2.37 1.31 2.26 2.66 1.78 2.28
Nucleus -0.66 -0.33 1.23 1.00 2.33 0.22 1.19 2.17 0.71 0.97 -0.36 0.95 2.68 1.25 1.43
Peroxisomes 1.16 11.70 14.55 14.51 -1.86 5.70 0.52 10.16 7.72 10.04 4.46 3.68 18.05 15.57 15.48
Vacuole -2.10 -3.65 -3.59 -2.86 1.02 -1.34 -2.37 -2.58 -2.52 -2.23 -2.25 -3.57 -4.35 -3.93 -2.97
Vacuole Periphery -1.23 0.51 1.37 1.47 1.16 -2.85 2.07 -1.19 -1.03 -1.23 -2.03 2.46 -1.09 -0.37 -1.23
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis; mutations in human PEX1 can lead to severe peroxisomal disorders and early death
Localization
Cell Percentages peroxisome (52%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Pex1

Pex1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pex1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available