Standard name
Human Ortholog
Description Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; links the (VFT/GARP) complex to the SNARE Tlg1p; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.11 0.06 0.05 0.05 – 0.06 0.08 0.08 0.06 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.05 0.08 0.07 0.08 0 – 0 0 0 0 0 0.06 0.06 0.07 0.14 0.17 0.2 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.32 0.2 0 0 0.12 0 – 0 0 0 0 0 0.33 0.24 0.45 0.42 0.34 0.33 0.35 0.31 0.34 0.28 0.29 0.28
Golgi 0 0.1 0 0 0 0 – 0 0 0 0 0 0.11 0.09 0 0.07 0 0 0.14 0.27 0.06 0.21 0.23 0.28
Mitochondria 0.67 0.65 0.85 0.89 0.68 0.92 – 0.86 0.92 0.87 0.91 0.9 0.44 0.59 0.31 0.1 0.11 0.08 0.18 0.14 0.18 0.09 0.12 0.12
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.25 0.14 0 0.15 0.22 0 – 0.08 0 0.1 0.07 0.07 0.17 0.07 0.21 0.23 0.32 0.29 0.21 0.17 0.3 0.35 0.28 0.23
SpindlePole 0.12 0.05 0.14 0.07 0.11 0.06 – 0.12 0.06 0.08 0.08 0.05 0.08 0 0.13 0.46 0.37 0.4 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 5 4 0 4 2 – 2 0 2 2 2 6 1 0 0 2 1 31 21 4 2 3 5
Bud 17 6 41 16 19 29 – 52 46 52 29 32 4 2 3 3 11 1 3 2 0 0 0 0
Bud Neck 3 0 7 0 1 0 – 3 0 1 0 0 0 0 0 1 0 0 3 1 0 0 0 0
Bud Site 8 0 4 1 7 5 – 16 11 16 12 12 0 0 0 1 1 2 – – – – – –
Cell Periphery 3 3 0 3 1 1 – 0 3 3 1 3 1 0 0 0 2 4 0 0 0 0 0 0
Cytoplasm 30 22 29 18 29 13 – 35 14 21 14 11 6 6 10 48 52 59 1 2 1 0 0 0
Endoplasmic Reticulum 1 12 3 2 5 4 – 2 3 3 3 6 8 3 1 6 4 6 0 1 3 0 0 0
Endosome 213 92 2 3 45 5 – 18 9 10 5 8 36 23 66 147 106 101 267 182 142 34 41 44
Golgi 0 49 0 0 0 0 – 0 0 0 0 1 12 8 6 24 12 11 107 157 24 25 32 44
Mitochondria 449 304 314 247 249 509 – 694 499 542 414 410 48 55 45 36 35 25 133 80 75 11 17 19
Nucleus 2 0 0 2 2 2 – 6 2 7 2 1 0 2 1 8 8 7 2 0 0 0 0 0
Nuclear Periphery 0 0 0 0 1 3 – 5 5 2 10 7 0 1 1 0 1 1 1 1 2 0 0 0
Nucleolus 13 3 0 4 6 16 – 28 17 8 15 10 0 0 1 4 8 7 3 0 0 0 0 0
Peroxisomes 166 67 13 41 80 23 – 65 17 61 30 33 19 7 31 80 100 89 155 97 125 43 40 37
SpindlePole 81 22 50 19 40 33 – 94 32 51 36 24 9 4 19 161 117 120 23 12 15 1 2 4
Vac/Vac Membrane 21 16 3 0 3 6 – 7 6 6 3 7 3 2 4 19 13 13 14 12 6 0 2 0
Unique Cell Count 668 468 370 276 367 556 811 542 624 454 458 109 94 146 353 314 302 756 579 414 123 142 160
Labelled Cell Count 1008 601 470 356 492 651 1027 664 785 576 567 152 114 188 538 472 447 756 579 414 123 142 160


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.9 5.9 3.7 3.8 4.6 3.8 – 4.0 3.8 4.2 4.0 4.2 5.8 5.8 5.7 7.9 7.6 7.7 5.4 5.9 6.0
Std Deviation (1e-4) 0.7 0.9 0.7 1.1 1.3 0.9 – 1.0 1.1 1.1 1.0 1.2 1.1 1.2 1.0 2.1 2.2 2.4 1.0 1.2 1.1
Intensity Change (Log2) – – – 0.03 0.32 0.03 – 0.11 0.02 0.18 0.1 0.17 0.63 0.63 0.62 1.08 1.02 1.04 0.54 0.67 0.68

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 – 0 0 0 0 0 -2.3 -2.7 -3.3 -5.8 -3.7 -5.7
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.6 0 -3.9 – -2.5 -3.7 -3.1 -3.1 -3.6 -0.8 -0.5 -0.4 2.5 3.5 4.5
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 – 0 0 0 0 0 11.0 9.2 13.5 13.7 11.9 11.8
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 5.1 3.8 0
Mitochondria 0 0 0 – 0 0 0 0 0 -8.7 -5.7 -12.0 -20.1 -19.2 -19.8
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 5.1 0 6.5 7.7 9.9 9.3
SpindlePole 0 0 0 – 0 0 0 0 0 -1.5 -2.5 -0.2 9.5 7.2 7.8
Vacuole 0 0 0 – 0 0 0 0 0 0 0 0 3.6 2.9 3.0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.0626 1.1981 1.2756 1.0832 1.2855 1.0349 0.6488 0.6733 0.8177 0.6603 0.8862 0.5485 2.0619 2.01 1.6753 1.3673 2.7996 2.2155
Actin 0.0153 0.0041 0.0172 0.0178 0.0209 0.0065 0.0285 0.0071 0.0449 0.036 0.0131 0.0105 0.0763 0.0139 0.0294 0.0094 0.0854 0.0028
Bud 0.0004 0.0071 0.0006 0.0043 0.0008 0.0005 0.0006 0.0049 0.0007 0.0015 0.0004 0.0089 0.0022 0.0029 0.0018 0.0001 0.0006 0.0001
Bud Neck 0.0013 0.0006 0.0021 0.0032 0.0017 0.0019 0.0027 0.0006 0.0014 0.0002 0.0008 0.001 0.0049 0.0037 0.0005 0.0004 0.0024 0.0023
Bud Periphery 0.0005 0.0026 0.0006 0.0046 0.001 0.0004 0.0006 0.0023 0.001 0.001 0.0005 0.0086 0.0029 0.0007 0.0011 0.0001 0.0007 0.0001
Bud Site 0.0019 0.0111 0.0026 0.0025 0.0044 0.0005 0.0063 0.0058 0.006 0.0007 0.0009 0.0006 0.0165 0.0126 0.0026 0.0003 0.0028 0.0002
Cell Periphery 0.0001 0.0002 0.0001 0.0003 0.0001 0.0001 0.0002 0.0002 0.0003 0.0002 0.0001 0.0004 0.0007 0.0003 0.0002 0 0.0004 0
Cytoplasm 0.0047 0.0112 0.0081 0.0055 0.0198 0.0109 0.0264 0.0196 0.0062 0.0112 0.0026 0.0262 0.0148 0.0159 0.0153 0.0075 0.0215 0.0141
Cytoplasmic Foci 0.1914 0.2674 0.2073 0.172 0.265 0.2105 0.2246 0.2693 0.2296 0.2656 0.2167 0.2512 0.2043 0.2489 0.2311 0.2064 0.1915 0.2492
Eisosomes 0.0002 0 0.0001 0.0003 0.0002 0 0.0003 0.0001 0.0003 0.0002 0.0004 0.0001 0.0009 0.0002 0.0001 0 0.0003 0
Endoplasmic Reticulum 0.0014 0.0007 0.0011 0.0004 0.0006 0.0006 0.0042 0.0015 0.0009 0.0008 0.0005 0.001 0.0061 0.0011 0.0017 0.001 0.0107 0.0004
Endosome 0.2486 0.2742 0.2635 0.2487 0.1788 0.1887 0.2094 0.1884 0.1883 0.195 0.1359 0.138 0.1587 0.1905 0.1841 0.2815 0.3213 0.1906
Golgi 0.135 0.1436 0.1621 0.1558 0.1148 0.1345 0.1024 0.119 0.1699 0.0824 0.1197 0.1025 0.1032 0.1448 0.1441 0.1413 0.1327 0.1848
Lipid Particles 0.1226 0.0649 0.0867 0.0713 0.1147 0.1013 0.1561 0.0703 0.0638 0.0817 0.0493 0.1069 0.1318 0.0931 0.0801 0.0778 0.0531 0.1088
Mitochondria 0.0244 0.0167 0.0237 0.0469 0.0467 0.0173 0.0172 0.0277 0.0376 0.0095 0.0571 0.0053 0.0299 0.0219 0.0273 0.0114 0.0082 0.0059
None 0.0036 0.0039 0.0111 0.034 0.0127 0.0035 0.062 0.0224 0.0347 0.1258 0.0426 0.0262 0.0357 0.0091 0.022 0.0017 0.0067 0.027
Nuclear Periphery 0.0072 0.0003 0.0015 0.0002 0.0017 0.0007 0.0047 0.0013 0.0005 0.0009 0.0008 0.0004 0.0222 0.0004 0.0034 0.0002 0.0358 0.0002
Nucleolus 0.0005 0.0004 0.0003 0.0005 0.0009 0.0002 0.0006 0.0009 0.0004 0.0005 0.0021 0.0003 0.0018 0.0007 0.0008 0.0001 0.0007 0.0001
Nucleus 0.0037 0.0006 0.0005 0.0003 0.0018 0.0003 0.0016 0.0008 0.0003 0.001 0.0008 0.0003 0.0074 0.0006 0.0033 0.0001 0.0152 0.0001
Peroxisomes 0.2292 0.1785 0.2044 0.2254 0.2033 0.3165 0.1422 0.2474 0.2082 0.1784 0.3489 0.3074 0.1507 0.2335 0.2456 0.2569 0.0969 0.2103
Punctate Nuclear 0.0032 0.0069 0.0028 0.0022 0.0063 0.0016 0.0044 0.0024 0.0015 0.0037 0.0042 0.0022 0.021 0.0021 0.0032 0.0007 0.0074 0.001
Vacuole 0.0029 0.0037 0.0022 0.0022 0.0025 0.0022 0.0032 0.0067 0.0023 0.0029 0.0009 0.0014 0.0045 0.0022 0.0016 0.0021 0.0033 0.0012
Vacuole Periphery 0.0018 0.0011 0.0014 0.0015 0.0014 0.0011 0.0018 0.0015 0.0012 0.001 0.0014 0.0006 0.0033 0.0009 0.0008 0.001 0.0024 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.5727 11.9561 4.436 8.311 7.2253 6.6836 11.5851 14.2784 11.0024 10.1919
Translational Efficiency 6.3729 1.7972 5.2528 3.3649 4.3741 4.7211 2.3154 2.7826 3.3377 3.3017

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1419 1551 303 1029 1882 1783 2221 680 3301 3334 2524 1709

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 709.98 750.76 991.34 900.82 608.10 785.35 870.72 879.44 651.90 769.26 885.20 892.31
Standard Deviation 77.38 104.17 118.26 129.71 74.92 99.29 102.29 117.85 91.21 103.05 111.46 125.56
Intensity Change Log 2 — 0.080573 0.481602 0.343460 — 0.369027 0.517900 0.532277 — 0.220844 0.498462 0.433650

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001100 0.002851 0.015223 0.016338 0.000656 0.002278 0.007177 0.019142 0.000847 0.002545 0.008143 0.017454
Bud Neck 0.001567 0.001245 0.002806 0.003014 0.003489 0.000881 0.003981 0.002775 0.002663 0.001050 0.003840 0.002919
Bud Site 0.001476 0.001609 0.013457 0.023226 0.001708 0.001921 0.009569 0.014866 0.001608 0.001776 0.010036 0.019900
Cell Periphery 0.000056 0.000030 0.000075 0.000093 0.000056 0.000041 0.000040 0.000040 0.000056 0.000036 0.000044 0.000072
Cytoplasm 0.006443 0.002916 0.001976 0.009102 0.006940 0.002061 0.011224 0.011999 0.006727 0.002459 0.010113 0.010255
Cytoplasmic Foci 0.295952 0.316047 0.350947 0.300994 0.250492 0.280192 0.323025 0.315630 0.270034 0.296872 0.326377 0.306818
Eisosomes 0.000119 0.000071 0.000069 0.000072 0.000109 0.000088 0.000061 0.000062 0.000113 0.000080 0.000062 0.000068
Endoplasmic Reticulum 0.000112 0.000110 0.001983 0.001538 0.000196 0.000132 0.000818 0.000508 0.000160 0.000122 0.000958 0.001128
Endosome 0.088151 0.148836 0.128626 0.203129 0.175286 0.163664 0.136240 0.171222 0.137829 0.156765 0.135326 0.190433
Golgi 0.406447 0.370928 0.103222 0.083961 0.339648 0.389460 0.059644 0.078860 0.368363 0.380839 0.064875 0.081932
Lipid Particles 0.027750 0.019703 0.033889 0.012397 0.064653 0.016429 0.036942 0.010680 0.048790 0.017952 0.036575 0.011714
Mitochondria 0.032772 0.019682 0.001969 0.008756 0.050565 0.031344 0.009082 0.005857 0.042916 0.025919 0.008228 0.007602
Mitotic Spindle 0.007007 0.017484 0.191310 0.122581 0.005835 0.009639 0.190154 0.080883 0.006339 0.013288 0.190293 0.105989
None 0.000150 0.000384 0.000023 0.000047 0.000743 0.000043 0.000226 0.000184 0.000488 0.000202 0.000201 0.000101
Nuclear Periphery 0.000079 0.000031 0.000333 0.000502 0.000072 0.000041 0.000292 0.000097 0.000075 0.000037 0.000297 0.000341
Nuclear Periphery Foci 0.000420 0.000521 0.006545 0.002522 0.000925 0.000139 0.002179 0.000650 0.000708 0.000317 0.002703 0.001777
Nucleolus 0.000309 0.000438 0.000776 0.000229 0.004637 0.000433 0.001515 0.000550 0.002777 0.000435 0.001427 0.000357
Nucleus 0.000324 0.000238 0.000705 0.000493 0.002533 0.001144 0.002323 0.001195 0.001583 0.000723 0.002129 0.000772
Peroxisomes 0.127184 0.094422 0.132383 0.171838 0.087449 0.095840 0.186511 0.263391 0.104530 0.095180 0.180013 0.208266
Vacuole 0.001591 0.001688 0.012849 0.033558 0.002748 0.002597 0.018464 0.019276 0.002251 0.002174 0.017790 0.027875
Vacuole Periphery 0.000990 0.000766 0.000835 0.005610 0.001260 0.001634 0.000532 0.002132 0.001144 0.001230 0.000568 0.004226

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.23 -5.72 -6.98 -5.99 -0.13 -4.27 -8.92 -5.84 -5.28 -3.72 -5.25 -10.35 -9.12 -8.06 -4.78
Bud Neck 0.77 -1.87 -5.29 -5.15 -0.77 6.06 -2.47 0.57 -5.29 3.10 5.37 -4.95 -2.08 -7.82 3.03
Bud Site -0.29 -3.99 -10.06 -9.93 -2.87 -0.44 -8.60 -7.47 -7.26 -3.04 -0.50 -9.67 -12.36 -12.15 -6.20
Cell Periphery 2.82 -1.95 -2.47 -4.85 -0.97 2.16 2.77 2.70 -0.22 0.13 3.62 1.85 -1.87 -4.39 -3.22
Cytoplasm 3.01 2.35 -2.90 -5.72 -4.85 5.42 -4.94 -3.34 -5.62 -0.43 5.91 -4.95 -4.40 -8.21 0.00
Cytoplasmic Foci -3.29 -3.46 0.37 2.93 3.47 -5.37 -10.88 -6.62 -3.31 0.88 -6.48 -9.41 -4.98 -0.44 3.09
Eisosomes 5.51 5.20 5.36 -0.42 -0.34 1.93 5.59 5.25 2.47 0.28 4.61 8.42 6.93 1.47 -0.81
Endoplasmic Reticulum 0.00 -3.58 -3.67 -3.68 0.88 1.10 -3.46 -2.24 -2.57 0.81 0.99 -4.65 -4.16 -4.34 -0.38
Endosome -12.09 -4.86 -15.80 -6.79 -7.38 1.70 7.32 0.90 -0.38 -4.53 -4.79 1.27 -8.88 -5.39 -9.60
Golgi 3.99 31.40 41.81 41.64 2.73 -6.64 46.87 36.83 45.62 -4.17 -2.36 63.99 54.75 61.62 -4.79
Lipid Particles 2.84 -1.22 5.93 3.01 4.08 13.03 6.55 14.22 2.38 10.08 12.56 3.72 15.24 3.69 11.40
Mitochondria 4.54 13.04 9.55 5.12 -4.29 5.26 14.27 14.25 9.44 1.99 7.07 17.32 17.03 10.51 0.72
Mitotic Spindle -5.11 -11.20 -16.09 -14.39 3.57 -3.18 -31.12 -11.44 -10.79 11.55 -6.05 -33.05 -19.71 -18.14 10.69
None -1.03 3.66 2.86 1.44 -2.31 6.84 3.66 3.67 -1.57 0.43 2.54 2.64 5.07 0.71 1.47
Nuclear Periphery 0.88 -2.11 -2.68 -3.13 -0.80 1.63 -9.13 -2.78 -3.51 5.89 1.54 -7.95 -3.07 -3.56 0.41
Nuclear Periphery Foci -0.32 -2.23 -4.14 -4.06 1.26 4.11 -4.62 -0.21 -4.25 4.40 2.45 -5.42 -3.76 -5.16 1.84
Nucleolus -0.66 -1.05 -0.64 0.22 0.86 4.88 2.49 3.85 -1.13 2.32 4.73 1.10 4.17 -0.90 3.91
Nucleus 0.35 -1.62 -2.61 -2.63 0.66 1.77 -1.87 0.65 -0.78 2.13 1.91 -3.35 0.90 -0.96 3.96
Peroxisomes 5.10 -0.40 -4.57 -8.51 -2.52 -1.58 -15.25 -15.19 -14.17 -6.58 2.31 -12.73 -14.37 -15.63 -3.75
Vacuole -0.51 -4.34 -12.97 -12.91 -5.56 0.30 -14.25 -8.33 -8.32 -0.55 0.06 -15.17 -15.29 -15.24 -4.66
Vacuole Periphery 1.43 0.52 -3.82 -4.03 -3.89 -1.31 6.30 -0.75 -0.37 -1.44 -0.52 6.02 -3.59 -3.43 -4.32
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; links the (VFT/GARP) complex to the SNARE Tlg1p; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p
Localization
Cell Percentages mitochondrion (15%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Vps51

Vps51


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Vps51-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available