Standard name
Human Ortholog
Description ER integral membrane protein, ERMES complex subunit; ERMES links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; required for mitophagy; ERMES complex is often co-localized with peroxisomes and with concentrated areas of pyruvate dehydrogenase
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0.08 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Bud – 0.05 0.1 0.06 0.07 0.05 0.05 0.07 0.1 0.09 0.14 0.09 – – – 0.09 0.07 0.1 0 0 0 0 0.05 0
Bud Neck – 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0.05 0.07 0 0.05 0.09 0
Bud Site – 0.05 0 0 0 0.05 0 0 0.07 0.06 0 0.06 – – – 0.06 0.06 0.07 – – – – – –
Cell Periphery – 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Cytoplasm – 0.22 0.28 0.28 0.31 0.29 0.26 0.24 0.23 0.15 0.11 0.12 – – – 0.07 0.07 0.06 0.24 0.1 0.09 0.13 0.21 0.06
Endoplasmic Reticulum – 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Endosome – 0 0.11 0.13 0.09 0.1 0.08 0.07 0.05 0.06 0 0.05 – – – 0.12 0.18 0.16 0.15 0.22 0.15 0.24 0.09 0.17
Golgi – 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Mitochondria – 0.62 0.13 0.21 0.18 0.29 0.28 0.32 0.4 0.44 0.53 0.46 – – – 0.09 0.06 0.07 0 0.09 0.06 0 0.07 0.05
Nucleus – 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Nuclear Periphery – 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Nucleolus – 0.05 0 0 0 0.05 0.05 0 0.06 0 0.05 0 – – – 0.06 0.06 0.06 0.05 0 0 0 0 0
Peroxisomes – 0.11 0.24 0.23 0.2 0.16 0.2 0.15 0.15 0.15 0.14 0.22 – – – 0.47 0.45 0.41 0.1 0.16 0.18 0.28 0.08 0.25
SpindlePole – 0.22 0.43 0.39 0.41 0.35 0.43 0.41 0.35 0.4 0.35 0.33 – – – 0.59 0.64 0.61 0.23 0.16 0.32 0.24 0.16 0.19
Vac/Vac Membrane – 0 0 0 0 0 0 0 0 0 0 0 – – – 0 0 0 0.06 0.05 0 0 0.06 0.1
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 3 2 0 1 0 0 2 0 1 0 2 – – – 1 1 1 0 2 8 0 0 0
Bud – 2 26 13 22 16 24 31 31 37 38 36 – – – 11 21 17 0 1 9 0 1 0
Bud Neck – 0 5 2 1 3 5 12 6 7 4 2 – – – 0 1 0 1 5 10 0 2 0
Bud Site – 2 6 5 8 14 17 20 21 24 12 22 – – – 8 18 13 – – – – – –
Cell Periphery – 0 0 0 0 1 0 0 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Cytoplasm – 8 74 63 99 84 116 111 74 61 30 49 – – – 9 22 10 5 8 26 2 5 1
Endoplasmic Reticulum – 0 0 0 0 0 0 0 2 0 1 0 – – – 1 2 1 0 0 0 0 0 0
Endosome – 1 29 29 29 29 34 31 15 22 11 21 – – – 15 58 28 3 17 44 4 2 3
Golgi – 0 0 0 0 0 0 0 0 0 0 0 – – – 0 2 1 0 0 0 0 0 0
Mitochondria – 23 34 47 59 84 125 146 127 177 145 179 – – – 11 18 13 0 7 16 0 2 1
Nucleus – 0 4 8 12 9 16 17 13 8 7 14 – – – 1 2 2 0 1 3 0 0 0
Nuclear Periphery – 0 1 0 0 0 0 1 0 0 0 0 – – – 2 0 0 0 0 1 0 0 0
Nucleolus – 2 7 3 5 15 21 20 19 16 15 13 – – – 7 20 10 1 1 4 0 0 0
Peroxisomes – 4 62 53 66 48 88 67 48 60 39 85 – – – 58 146 73 2 13 53 4 2 5
SpindlePole – 8 112 90 132 103 193 186 110 160 96 131 – – – 73 205 108 5 12 93 4 4 4
Vac/Vac Membrane – 1 6 2 5 4 0 1 0 5 2 4 – – – 0 2 0 1 4 9 0 1 2
Unique Cell Count 37 263 229 323 293 449 457 318 399 273 392 124 321 178 23 81 291 17 28 23
Labelled Cell Count 54 368 315 439 410 639 645 466 578 400 558 197 518 277 23 81 291 17 28 23


Mitochondria, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 4.1 3.7 3.9 3.5 3.4 3.4 3.7 3.3 3.5 3.7 3.8 – – – 5.3 6.2 7.2 – – –
Std Deviation (1e-4) – 1.1 1.0 1.3 1.2 1.3 1.5 1.4 1.3 1.4 1.4 1.4 – – – 1.2 1.4 1.9 – – –
Intensity Change (Log2) – – – 0.08 -0.05 -0.1 -0.1 -0.0 -0.16 -0.07 -0.01 0.04 – – – 0.52 0.76 0.97 – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.003 0.0142 0.0152 0.049 0.0014 0.0089 0.0113 0.0009 0.0187 0.0021 0.0011 0.0087 0.0002 0.0008 0.0004 0.0031 0.0017 0.0009
Bud 0.0003 0.0016 0.001 0.0003 0.0002 0.0009 0.0001 0.0117 0.0005 0 0.0001 0 0 0 0.0001 0 0 0.0001
Bud Neck 0.0005 0.0032 0.0135 0.0147 0.027 0.0216 0.0025 0.0018 0.0217 0.0001 0.0001 0.0025 0.0001 0 0.1657 0.0002 0.0001 0.0003
Bud Periphery 0.0004 0.0035 0.0031 0.0006 0.0005 0.0017 0.0001 0.0101 0.0005 0 0.0002 0.0001 0 0 0.0001 0 0 0.0002
Bud Site 0.0013 0.0269 0.0075 0.0018 0.001 0.0014 0.0007 0.0707 0.0412 0.0003 0.0004 0.0001 0.0003 0 0.0004 0.0001 0.0001 0.0001
Cell Periphery 0.0002 0.0013 0.0004 0.0003 0.0001 0.0005 0.0002 0.0025 0.001 0 0.0001 0.0001 0.0001 0 0.0002 0 0 0.0004
Cytoplasm 0.0314 0.0618 0.0376 0.0122 0.0336 0.0657 0.0499 0.1017 0.0251 0.0007 0.1568 0.0561 0.1055 0 0.1482 0.0032 0.0001 0.1271
Cytoplasmic Foci 0.2497 0.2034 0.2332 0.2085 0.2293 0.2788 0.2212 0.1736 0.3296 0.1675 0.1468 0.353 0.1678 0.1029 0.2289 0.6559 0.1392 0.1393
Eisosomes 0.0005 0.0008 0.0006 0.0004 0.0003 0.0003 0.0012 0.0006 0.0005 0 0.0001 0.0003 0 0 0 0 0 0.0002
Endoplasmic Reticulum 0.0014 0.0011 0.0021 0.0002 0.0005 0.0007 0.0011 0.0027 0.0013 0.0001 0.0021 0.0007 0.0045 0 0.002 0 0 0.0374
Endosome 0.0377 0.0319 0.0355 0.0185 0.0338 0.019 0.0186 0.0065 0.0324 0.0064 0.0296 0.0218 0.1329 0.0045 0.0123 0.0028 0.0042 0.0176
Golgi 0.0073 0.0068 0.0084 0.011 0.005 0.0067 0.0037 0.0031 0.0062 0.0052 0.0063 0.0038 0.0052 0.0162 0.0011 0.0042 0.0104 0.0032
Lipid Particles 0.0687 0.0445 0.0251 0.0221 0.0183 0.0557 0.062 0.0304 0.028 0.0196 0.0239 0.0416 0.0205 0.1399 0.0023 0.1098 0.0943 0.0366
Mitochondria 0.0024 0.0081 0.0103 0.0239 0.0032 0.005 0.0028 0.0055 0.0033 0.0005 0.0017 0.0009 0.001 0.0006 0.0009 0.0004 0.0015 0.0038
None 0.4614 0.4377 0.4712 0.3756 0.5454 0.3654 0.5191 0.4436 0.2817 0.0013 0.5147 0.367 0.5491 0 0.4193 0.0143 0.0001 0.3822
Nuclear Periphery 0.0023 0.0007 0.0039 0.0001 0.0004 0.001 0.0008 0.001 0.001 0.0001 0.0006 0.0008 0.0011 0 0.0007 0 0 0.0028
Nucleolus 0.0024 0.0025 0.003 0.0008 0.0022 0.0017 0.0013 0.0175 0.0101 0.0001 0.0002 0.0002 0.0001 0 0.0002 0.0001 0 0.0003
Nucleus 0.0075 0.0028 0.0031 0.0003 0.0016 0.0026 0.0007 0.0042 0.0026 0.0001 0.0008 0.0005 0.0004 0 0.0009 0 0 0.0005
Peroxisomes 0.0933 0.1227 0.0934 0.2552 0.0861 0.114 0.0912 0.1028 0.1377 0.7763 0.1074 0.1132 0.0041 0.7337 0.0078 0.1991 0.7477 0.2423
Punctate Nuclear 0.0246 0.0179 0.0202 0.0033 0.0061 0.0406 0.0096 0.0047 0.0456 0.0194 0.0014 0.0267 0.0016 0.0011 0.002 0.0066 0.0007 0.0018
Vacuole 0.003 0.0063 0.0096 0.001 0.0035 0.0067 0.0018 0.0042 0.0103 0 0.0051 0.0018 0.0046 0 0.0059 0 0 0.0022
Vacuole Periphery 0.0007 0.0005 0.002 0.0003 0.0004 0.001 0.0002 0.0003 0.0009 0 0.0005 0.0002 0.0008 0 0.0006 0 0 0.0007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 16.7966 9.2401 13.1417 16.6379 17.3103 18.0786 18.8799 22.0697 20.5718 17.9514
Translational Efficiency 0.5935 1.2519 1.094 0.7656 0.6447 0.6862 0.8908 0.5873 0.8181 0.8197

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
88 163 173 310 1552 1150 1778 1354 1640 1313 1951 1664

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 927.33 702.81 779.63 1078.22 616.27 702.82 840.41 977.90 632.96 702.82 835.02 996.59
Standard Deviation 142.70 118.66 122.86 244.44 81.12 108.12 147.76 235.75 110.60 109.49 146.74 240.59
Intensity Change Log 2 — -0.399948 -0.250293 0.217497 — 0.189593 0.447531 0.666124 — -0.135082 0.069730 0.413626

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.013977 0.006733 0.002307 0.036063 0.000572 0.000617 0.006978 0.061525 0.001292 0.001377 0.006564 0.056781
Bud Neck 0.020653 0.138574 0.015494 0.023154 0.163725 0.177580 0.023611 0.019960 0.156048 0.172738 0.022892 0.020555
Bud Site 0.046807 0.037827 0.028409 0.061466 0.033079 0.023879 0.071593 0.064462 0.033815 0.025610 0.067764 0.063904
Cell Periphery 0.000248 0.000271 0.000316 0.000230 0.000765 0.000526 0.000226 0.000360 0.000737 0.000494 0.000234 0.000336
Cytoplasm 0.052193 0.181972* 0.101735* 0.031164 0.094107 0.105956* 0.153951* 0.055902 0.091858 0.115393* 0.149321* 0.051293
Cytoplasmic Foci 0.181612* 0.190913* 0.102238 0.233458* 0.249604* 0.143406 0.186838* 0.172432 0.245955* 0.149304 0.179336 0.183801*
Eisosomes 0.000147 0.000225 0.000130 0.000169 0.000180 0.000183 0.000095 0.000344 0.000178 0.000188 0.000098 0.000312
Endoplasmic Reticulum 0.003415 0.000601 0.006708 0.005110 0.000507 0.000663 0.001621 0.001589 0.000663 0.000656 0.002072 0.002245
Endosome 0.073387 0.055379 0.016651 0.068257 0.071675 0.110248 0.019902 0.051712 0.071767 0.103436 0.019614 0.054794
Golgi 0.021717 0.005381 0.004174 0.024402 0.026061 0.017761 0.007168 0.038080 0.025828 0.016224 0.006902 0.035532
Lipid Particles 0.043527 0.010292 0.015163 0.050001 0.023109 0.026688 0.016751 0.079859 0.024205 0.024653 0.016610 0.074296
Mitochondria 0.000788 0.020201 0.001142 0.004946 0.039343 0.033127 0.001672 0.003049 0.037274 0.031522 0.001625 0.003403
Mitotic Spindle 0.016577 0.011662 0.018965 0.100355* 0.007578 0.008577 0.107767* 0.042037 0.008061 0.008960 0.099892 0.052901
None 0.001730 0.003812 0.005795 0.004848 0.007597 0.005787 0.002125 0.001220 0.007283 0.005542 0.002451 0.001896
Nuclear Periphery 0.000612 0.000547 0.001284 0.000599 0.000269 0.000615 0.001070 0.000300 0.000287 0.000607 0.001089 0.000355
Nuclear Periphery Foci 0.002874 0.000431 0.008288 0.003210 0.001297 0.000438 0.002538 0.002538 0.001382 0.000437 0.003048 0.002663
Nucleolus 0.003491 0.010570 0.004256 0.001282 0.008337 0.012340 0.002981 0.001368 0.008077 0.012121 0.003094 0.001352
Nucleus 0.112490 0.121531 0.505827* 0.014928 0.066906 0.123849 0.149365* 0.025883 0.069352 0.123561 0.180974* 0.023842
Peroxisomes 0.326330* 0.124608* 0.119025* 0.292109* 0.171466* 0.130357* 0.212653* 0.352580* 0.179776* 0.129643* 0.204351* 0.341315*
Vacuole 0.076607 0.076085 0.041454 0.041960 0.031616 0.072685 0.030637 0.024094 0.034030 0.073107 0.031597 0.027423
Vacuole Periphery 0.000818 0.002386 0.000638 0.002287 0.002207 0.004715 0.000456 0.000707 0.002132 0.004426 0.000472 0.001001

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.98 2.62 -2.44 -2.92 -4.32 -0.25 -6.66 -13.82 -13.82 -12.31 -0.16 -5.82 -14.37 -14.13 -12.89
Bud Neck -5.37 0.61 -0.00 5.59 -0.85 -1.18 18.99 19.92 18.44 2.90 -1.46 18.94 19.83 19.26 2.65
Bud Site 0.66 1.06 -1.26 -3.00 -3.86 3.10 -8.80 -7.94 -10.48 -0.08 2.80 -8.16 -8.47 -11.11 -0.75
Cell Periphery 0.22 -0.63 0.52 0.45 1.62 2.15 5.25 3.73 2.14 -4.18 2.36 5.16 3.98 2.36 -3.57
Cytoplasm -5.27 -2.54 0.36 6.02 3.37 -1.79 -10.26 4.17 5.54 14.36 -3.47 -10.32 4.58 7.60 15.10
Cytoplasmic Foci -0.99 3.21 -1.99 -1.05 -6.43 12.63 10.74 10.09 -2.83 -0.70 11.89 11.45 8.98 -3.39 -2.86
Eisosomes -1.06 0.82 0.75 1.92 -0.15 -0.31 6.40 -6.92 -7.02 -11.47 -0.67 6.29 -6.33 -6.14 -11.46
Endoplasmic Reticulum 2.43 -1.71 0.20 -1.33 1.46 -1.59 -11.04 -4.87 -4.32 2.93 0.67 -10.38 -2.67 -2.88 1.65
Endosome 0.92 4.06 0.53 -0.57 -5.33 -6.18 14.08 5.09 10.40 -10.03 -5.53 14.62 4.81 9.74 -11.43
Golgi 3.45 3.90 -0.35 -4.94 -5.54 4.22 14.08 -3.86 -7.39 -15.36 5.19 14.57 -3.16 -7.86 -16.13
Lipid Particles 2.66 2.25 -0.04 -4.41 -3.62 -0.95 3.66 -10.09 -8.88 -12.38 -0.05 4.15 -9.90 -9.42 -12.89
Mitochondria -2.75 -0.24 -1.09 2.11 -1.06 1.51 12.74 12.18 9.81 -1.69 1.53 12.71 11.89 9.87 -1.81
Mitotic Spindle 1.39 -0.20 -6.43 -7.04 -5.85 -0.75 -18.66 -10.68 -10.01 9.02 -0.62 -18.47 -12.76 -12.20 6.61
None -1.08 -1.49 -0.69 -0.12 0.14 1.11 4.67 5.73 4.08 3.83 1.16 4.39 4.55 3.27 1.32
Nuclear Periphery 1.22 -1.77 0.93 -0.48 3.08 -3.91 -12.84 -2.82 2.08 11.67 -3.55 -13.17 -2.93 1.40 11.53
Nuclear Periphery Foci 2.75 -1.22 0.06 -4.20 1.32 4.77 -4.83 -2.82 -5.19 1.20 5.45 -4.84 -3.33 -6.46 1.47
Nucleolus -0.95 0.46 1.48 2.66 1.75 -2.89 2.14 6.73 8.48 5.51 -2.91 2.23 6.72 8.81 5.55
Nucleus 0.57 -8.38 3.99 6.22 15.60 -7.66 -14.25 6.27 12.77 19.48 -7.44 -16.72 7.60 14.24 23.30
Peroxisomes 4.39 4.96 0.94 -5.32 -6.17 4.44 0.51 -14.27 -17.62 -14.70 5.46 1.94 -13.40 -18.15 -15.33
Vacuole 0.25 1.39 0.05 -0.25 -1.82 -8.69 -6.71 -1.66 6.66 4.17 -8.68 -5.97 -3.16 5.10 1.85
Vacuole Periphery -2.48 0.62 -1.10 0.30 -1.36 -4.45 7.18 5.58 7.55 -1.68 -4.52 7.19 3.86 6.91 -2.13
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description ER integral membrane protein, ERMES complex subunit; ERMES links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; required for mitophagy; ERMES complex is often co-localized with peroxisomes and with concentrated areas of pyruvate dehydrogenase
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Mmm1

Mmm1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mmm1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available