Standard name
Human Ortholog
Description Phosphatidic acid transfer protein; plays a role in phospholipid metabolism by transporting phosphatidic acid from the outer to the inner mitochondrial membrane; localizes to the mitochondrial intermembrane space; null mutant has altered cardiolipin and phosphatidic acid levels; ortholog of human PRELI
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0.05
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.05 0 0.05 0.05 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.05 0.06 0.05 0.05 0 0.05 0 0 0 0 0 0 0 0 0.66 0.68 0.67 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0.08 0.09 0 0 0 0 0 0
Endosome 0.13 0 0.08 0.16 0.16 0 0.16 0.18 0.06 0 0.05 0.05 0.08 0.06 0.1 0.15 0.09 0.09 0.07 0 0.06 0.06 0.09 0.07
Golgi 0.06 0.09 0.26 0 0.13 0 0 0 0 0 0 0 0.11 0.18 0.19 0 0 0 0.08 0.11 0 0.09 0.09 0.09
Mitochondria 0.78 0.89 0.55 0.83 0.64 0.89 0.69 0.73 0.87 0.84 0.92 0.87 0.81 0.77 0.72 0.09 0.1 0.07 0.71 0.67 0.82 0.69 0.65 0.58
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0.18 0.08 0 0 0.05 0 0 0 0 0 0.07 0 0 0 0 0.05 0 0 0.07 0.07 0.06
SpindlePole 0 0 0.06 0.07 0 0 0.06 0.06 0 0 0 0.05 0 0 0 0.06 0.05 0 0 0 0 0 0 0
Vac/Vac Membrane 0.19 0.15 0.11 0.05 0.14 0.12 0.17 0.19 0.1 0.1 0.07 0.08 0.13 0.13 0.13 0.1 0.08 0.1 0 0.05 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 5 7 2 2 2 0 0 0 1 0 2 2 4 1 3 5 17 4 5 1 2 14 20
Bud 1 0 4 5 6 7 7 20 9 8 9 6 4 4 3 4 4 8 0 1 0 0 2 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 1 1 0 2 3 6
Bud Site 0 0 0 0 1 0 0 1 4 1 2 4 0 0 0 1 0 0 – – – – – –
Cell Periphery 8 6 3 11 13 3 1 4 2 2 1 3 10 13 6 5 10 5 0 0 0 0 1 0
Cytoplasm 0 6 6 11 14 9 17 19 6 12 5 7 5 9 10 206 213 215 0 0 0 0 0 2
Endoplasmic Reticulum 3 2 6 0 1 7 0 0 2 2 1 3 7 2 16 19 26 28 1 1 0 0 3 2
Endosome 35 4 8 38 45 4 56 94 17 15 13 16 16 21 34 45 28 28 21 6 8 15 37 27
Golgi 17 12 27 10 38 0 5 5 0 5 1 6 22 62 62 1 2 2 23 15 6 22 41 35
Mitochondria 217 116 58 194 185 230 237 384 261 308 251 269 164 260 239 29 31 22 217 98 128 174 283 218
Nucleus 1 0 1 2 3 4 3 13 5 8 2 2 0 2 3 2 2 6 0 0 0 0 2 0
Nuclear Periphery 9 3 0 0 1 9 7 19 4 13 7 17 5 1 3 0 0 0 3 1 0 1 1 1
Nucleolus 5 0 1 1 1 9 12 20 15 9 9 12 3 6 0 0 0 1 0 0 0 1 2 1
Peroxisomes 6 4 3 42 22 2 8 26 9 9 1 7 2 22 15 9 7 0 14 5 2 18 28 22
SpindlePole 3 0 6 16 11 5 22 31 12 8 4 14 2 1 1 18 15 10 3 0 0 0 3 7
Vac/Vac Membrane 54 19 12 11 40 30 57 102 29 35 18 25 26 43 42 30 26 32 12 6 4 8 9 22
Unique Cell Count 278 130 105 235 288 257 343 528 299 366 272 308 203 338 334 310 315 321 309 146 157 251 438 376
Labelled Cell Count 360 177 142 343 383 321 432 738 375 436 324 393 268 450 435 374 370 374 309 146 157 251 438 376


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.2 7.1 7.0 6.9 7.6 5.0 6.6 6.4 6.0 6.1 5.7 6.2 6.9 7.1 7.2 5.3 5.5 5.4 5.9 5.9 6.1
Std Deviation (1e-4) 0.9 2.1 1.3 1.7 1.8 1.2 1.6 1.4 1.5 1.6 1.5 1.6 1.2 1.2 1.1 1.0 0.9 1.0 1.2 1.0 1.7
Intensity Change (Log2) – – – -0.02 0.12 -0.48 -0.09 -0.13 -0.23 -0.2 -0.29 -0.18 -0.02 0.02 0.04 -0.4 -0.34 -0.37 -0.26 -0.25 -0.19


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -0.5
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.4 -0.3 0 -0.3 0 0 0 0 0 0 0 0 10.8 11.0 10.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 -0.4 0.2 0.8 1.0
Endosome 2.1 2.1 0 2.2 2.6 -0.7 -1.5 -1.1 -0.9 0.1 -0.5 0.8 1.8 0.4 0.4
Golgi -5.9 -3.0 -8.5 -8.4 -10.6 -9.1 -8.7 -8.4 -7.8 -3.4 -1.6 -1.6 -9.0 -8.8 -8.9
Mitochondria 5.3 1.6 7.3 2.6 3.6 6.9 6.3 8.4 7.0 4.7 4.3 3.1 -10.0 -9.9 -11.0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 3.8 1.7 0 0 0 0 0 0 0 0 1.4 0 0 0 0
SpindlePole 0.4 0 0 0.3 0.1 0 0 0 -0.5 0 0 0 0 -0.4 0
Vacuole -2.3 0.6 0.1 1.3 1.9 -0.5 -0.6 -1.5 -1.0 0.3 0.4 0.3 -0.5 -1.0 -0.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.1512 2.4559 2.3953 2.1524 2.4542 2.4545 3.5777 4.0503 4.2322 3.651 3.7653 3.9292 5.0281 5.909 5.6455 5.6252 5.1337 5.863
Actin 0.0218 0.0136 0.0023 0.0002 0.0151 0.0015 0.0117 0.0049 0.0117 0.0006 0.0034 0.0036 0.0093 0.0278 0.04 0.0495 0.0067 0.0102
Bud 0.0005 0.0005 0.0002 0 0.0005 0.0002 0.0006 0.0014 0.0003 0.0003 0.0009 0.0002 0.0008 0.002 0.0012 0.0018 0.0032 0.0019
Bud Neck 0.0003 0.0002 0.0019 0.0001 0.0002 0.0003 0.0013 0.0007 0.0002 0.0002 0.0006 0.0004 0.0008 0.001 0.0004 0.0004 0.0002 0.0014
Bud Periphery 0.0013 0.001 0.0004 0.0001 0.0009 0.0004 0.0012 0.0034 0.0005 0.0008 0.0017 0.0005 0.0013 0.0027 0.0035 0.0029 0.0062 0.007
Bud Site 0.0012 0.0014 0.0005 0.0001 0.0003 0.0002 0.0053 0.0105 0.001 0.0003 0.0011 0.0002 0.0097 0.0163 0.0047 0.0048 0.001 0.0004
Cell Periphery 0.0004 0.0002 0.0002 0 0.0002 0.0001 0.0005 0.0006 0.0002 0.0001 0.0002 0.0001 0.0008 0.001 0.0006 0.0003 0.0002 0.0007
Cytoplasm 0.0007 0.0029 0.0003 0 0.0007 0.0039 0.0009 0.0011 0.0004 0.0002 0.0015 0.0001 0.0005 0.0065 0.0021 0.0005 0.0025 0.0104
Cytoplasmic Foci 0.0175 0.0146 0.0074 0.0034 0.0051 0.017 0.0186 0.0271 0.0068 0.0061 0.021 0.0032 0.0196 0.0359 0.0156 0.0067 0.011 0.0081
Eisosomes 0.0007 0.0002 0.0001 0.0001 0.0002 0.0001 0.0003 0.0003 0.0004 0.0001 0.0001 0.0003 0.0003 0.0004 0.001 0.0005 0.0002 0.0003
Endoplasmic Reticulum 0.0005 0.0014 0.0001 0 0.0002 0.0002 0.0023 0.0009 0.0005 0.0002 0.0007 0.0003 0.0003 0.0014 0.001 0.0005 0.0005 0.0003
Endosome 0.035 0.041 0.0301 0.0138 0.0181 0.0226 0.0583 0.0545 0.0257 0.059 0.1 0.025 0.0392 0.0909 0.0433 0.0671 0.0712 0.0196
Golgi 0.0467 0.0371 0.0447 0.016 0.0448 0.0411 0.0652 0.0702 0.0463 0.0505 0.0682 0.0299 0.0578 0.0782 0.0642 0.0176 0.0651 0.0396
Lipid Particles 0.015 0.0107 0.0036 0.0028 0.0128 0.0082 0.0317 0.0124 0.0088 0.022 0.0052 0.0038 0.0329 0.0067 0.0076 0.0029 0.0088 0.0017
Mitochondria 0.8207 0.8433 0.8916 0.9551 0.8851 0.8664 0.7535 0.7845 0.8811 0.8483 0.7663 0.9095 0.7704 0.6694 0.7815 0.7787 0.7588 0.8776
None 0.0013 0.0002 0.0001 0 0.0001 0.0018 0.0007 0.0002 0.0011 0.0001 0.0003 0.0001 0.0005 0.0012 0.001 0.0002 0.0003 0.005
Nuclear Periphery 0.0005 0.0014 0.0001 0 0 0.0001 0.0019 0.0003 0.0016 0.0002 0.0007 0.0004 0.0002 0.0004 0.0013 0.0002 0.0003 0.0001
Nucleolus 0.0003 0.0002 0.0002 0 0.0001 0.0004 0.0021 0.0003 0.0002 0.0002 0.0002 0.0001 0.0004 0.0012 0.0002 0.0001 0.0001 0.0001
Nucleus 0.0003 0.0002 0.0001 0 0.0001 0.0002 0.0023 0.0003 0.0002 0.0001 0.0003 0.0001 0.0002 0.0007 0.0002 0.0001 0.0002 0.0001
Peroxisomes 0.023 0.0185 0.008 0.0069 0.0114 0.0311 0.0208 0.0179 0.0079 0.0042 0.0127 0.0087 0.0478 0.0334 0.0255 0.0595 0.0499 0.0128
Punctate Nuclear 0.0026 0.0001 0 0 0 0.0001 0.0014 0.0001 0.0005 0.0001 0.0001 0 0.0008 0.0002 0.0002 0.0004 0.0001 0
Vacuole 0.0049 0.0045 0.0043 0.0004 0.0019 0.0018 0.0111 0.0048 0.002 0.0032 0.0072 0.004 0.0033 0.0154 0.0029 0.0034 0.0074 0.0012
Vacuole Periphery 0.0049 0.0068 0.0039 0.0007 0.0022 0.0022 0.0082 0.0036 0.0027 0.0032 0.0078 0.0095 0.0033 0.0072 0.0021 0.0022 0.0061 0.0018

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 24.0325 24.2858 22.1798 25.1583 23.0307 27.1521 30.2219 28.6844 26.9514 28.9979
Translational Efficiency 1.6239 1.1538 1.1706 1.1024 1.5269 1.3633 1.4478 1.2468 1.3452 1.4501

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
283 141 118 205 1342 2507 246 741 1625 2648 364 946

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 722.27 920.54 1063.49 997.66 724.12 875.06 1034.43 911.32 723.80 877.48 1043.85 930.03
Standard Deviation 100.21 136.18 134.94 122.66 90.38 120.73 117.61 118.77 92.17 122.03 124.24 124.80
Intensity Change Log 2 — 0.349942 0.558196 0.466010 — 0.273153 0.514535 0.331729 — 0.312009 0.536503 0.400345

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000756 0.005184 0.017914 0.024543 0.000880 0.000666 0.011513 0.013255 0.000858 0.000907 0.013588 0.015701
Bud Neck 0.035488 0.006284 0.018270 0.007646 0.014014 0.009183 0.015943 0.016893 0.017754 0.009028 0.016697 0.014889
Bud Site 0.024916 0.032376 0.097041 0.118310* 0.027204 0.015828 0.129306* 0.114386* 0.026806 0.016710 0.118847* 0.115236*
Cell Periphery 0.002279 0.000695 0.000568 0.000248 0.000431 0.000652 0.000384 0.000552 0.000753 0.000654 0.000444 0.000486
Cytoplasm 0.026449 0.007832 0.063699 0.039872 0.036018 0.004742 0.055642 0.040280 0.034351 0.004906 0.058254 0.040192
Cytoplasmic Foci 0.083270 0.037789 0.160043 0.164023 0.098738 0.025668 0.151494 0.112499 0.096044 0.026313 0.154265 0.123664
Eisosomes 0.000146 0.000118 0.000212 0.000158 0.000104 0.000069 0.000170 0.000148 0.000111 0.000072 0.000184 0.000150
Endoplasmic Reticulum 0.000926 0.000813 0.008611 0.003200 0.001067 0.000424 0.005347 0.004440 0.001042 0.000444 0.006405 0.004171
Endosome 0.093587 0.095155 0.118427 0.084053 0.076895 0.080663 0.105897 0.103242 0.079802 0.081435 0.109959 0.099084
Golgi 0.060365 0.087087 0.074760 0.092847 0.098777 0.066926 0.078079 0.090367 0.092088 0.067999 0.077003 0.090905
Lipid Particles 0.006709 0.001651 0.012385 0.003218 0.005159 0.004421 0.006178 0.002452 0.005429 0.004273 0.008190 0.002618
Mitochondria 0.542021* 0.620419* 0.061474 0.054916 0.522069* 0.716006* 0.042095 0.219277* 0.525544* 0.710916* 0.048377 0.183660*
Mitotic Spindle 0.008906 0.011085 0.099060 0.249632* 0.017087 0.009013 0.137716* 0.097072 0.015662 0.009123 0.125185* 0.130132*
None 0.000410 0.000381 0.000339 0.000103 0.001855 0.001235 0.000312 0.000297 0.001603 0.001190 0.000321 0.000255
Nuclear Periphery 0.000223 0.000197 0.000931 0.000160 0.000218 0.000333 0.000644 0.000294 0.000219 0.000326 0.000737 0.000265
Nuclear Periphery Foci 0.000239 0.001274 0.007294 0.001090 0.000321 0.000742 0.002615 0.000805 0.000307 0.000770 0.004132 0.000867
Nucleolus 0.001637 0.000950 0.003978 0.000169 0.001819 0.001965 0.001584 0.000731 0.001788 0.001911 0.002360 0.000610
Nucleus 0.012541 0.000852 0.039795 0.002224 0.006370 0.001175 0.021924 0.005718 0.007444 0.001157 0.027717 0.004960
Peroxisomes 0.056824 0.042346 0.076361 0.082787 0.030057 0.022837 0.123508* 0.071269 0.034719 0.023876 0.108224* 0.073765
Vacuole 0.020113 0.029528 0.113574 0.066357 0.032817 0.023045 0.097920 0.085941 0.030604 0.023391 0.102995 0.081697
Vacuole Periphery 0.022196 0.017985 0.025264 0.004444 0.028101 0.014407 0.011731 0.020080 0.027073 0.014597 0.016118 0.016692

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.09 -4.30 -3.78 -2.84 -0.72 0.85 -6.18 -5.24 -5.36 -0.59 -0.20 -7.26 -6.45 -6.44 -0.60
Bud Neck 4.09 2.24 3.79 -1.19 2.88 2.95 -0.87 -1.31 -4.06 -0.41 4.66 0.47 1.25 -3.83 0.80
Bud Site -0.95 -5.08 -7.51 -6.14 -1.06 4.52 -8.54 -12.53 -14.71 0.93 4.43 -9.88 -14.52 -16.71 0.22
Cell Periphery 1.63 1.77 2.11 3.83 4.30 -1.96 0.62 -0.93 1.04 -1.53 0.49 1.72 1.53 1.77 -0.34
Cytoplasm 3.41 -3.16 -2.06 -5.16 1.70 10.11 -3.33 -2.41 -10.44 1.91 10.86 -4.29 -2.91 -11.85 2.44
Cytoplasmic Foci 4.52 -4.20 -5.57 -10.01 -0.36 18.02 -5.03 -1.63 -16.38 3.72 18.83 -6.35 -4.08 -19.87 3.24
Eisosomes 1.40 -2.86 -0.44 -1.37 1.79 6.10 -5.26 -2.70 -5.23 1.65 7.35 -6.48 -2.75 -6.02 2.50
Endoplasmic Reticulum 0.32 -5.87 -3.75 -3.84 3.78 4.52 -5.15 -2.15 -2.57 0.72 4.72 -7.62 -2.61 -3.11 1.95
Endosome -0.15 -1.23 1.36 1.33 2.36 -0.85 -2.55 -3.76 -3.27 0.10 -0.40 -3.15 -2.82 -2.61 1.20
Golgi -1.96 -0.62 -1.78 0.33 -0.87 6.54 3.11 2.17 -3.10 -1.50 5.45 2.95 1.39 -3.08 -1.79
Lipid Particles 2.85 -2.00 1.87 -1.62 3.04 0.80 -1.32 2.64 2.18 3.60 1.34 -2.51 3.04 1.73 4.72
Mitochondria -2.11 18.39 20.00 18.26 0.45 -16.89 40.96* 21.79 40.63* -13.09 -17.18 43.82* 27.95 49.10* -11.49
Mitotic Spindle -0.82 -4.48 -10.86 -10.76 -5.15 5.11 -7.83 -11.26 -12.46 1.80 4.70 -8.89 -15.08 -16.05 -0.86
None 0.28 0.64 5.20 2.59 3.57 0.94 2.31 2.54 3.18 1.07 0.74 2.36 2.66 3.37 1.69
Nuclear Periphery 0.18 -4.10 -0.57 -0.44 3.98 -0.82 -2.94 -1.86 -0.55 1.85 -0.83 -4.45 -1.89 -0.41 3.34
Nuclear Periphery Foci -1.29 -2.16 -4.16 -0.16 1.82 -1.93 -5.17 -3.13 -1.59 2.96 -2.25 -3.45 -4.15 -1.92 2.64
Nucleolus 0.72 -1.65 1.86 1.22 3.02 -0.20 0.19 2.33 1.96 1.81 -0.19 -1.10 2.91 2.24 3.28
Nucleus 2.93 -3.05 1.92 -3.07 3.81 5.26 -3.59 -0.77 -3.68 3.18 5.85 -4.87 0.11 -4.13 4.83
Peroxisomes 1.26 -1.18 -1.80 -3.01 -0.41 2.54 -7.57 -6.63 -8.37 3.91 3.75 -7.73 -6.93 -9.77 3.33
Vacuole -1.19 -7.03 -6.16 -4.93 1.15 4.21 -7.90 -10.16 -12.00 1.44 3.46 -10.26 -11.76 -13.24 1.95
Vacuole Periphery 0.89 -0.21 6.15 3.65 3.96 7.97 7.24 3.71 -2.17 -3.09 8.03 4.99 5.52 -0.61 -0.33
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Phosphatidic acid transfer protein; plays a role in phospholipid metabolism by transporting phosphatidic acid from the outer to the inner mitochondrial membrane; localizes to the mitochondrial intermembrane space; null mutant has altered cardiolipin and phosphatidic acid levels; ortholog of human PRELI
Localization
Cell Percentages mitochondrion (90%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Ups1

Ups1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ups1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available