Standard name
Human Ortholog
Description Protein involved in 20S proteasome assembly; forms a heterodimer with Add66p that binds to proteasome precursors; interaction with Pba1p-Add66p may affect function of the mature proteasome and its role in maintaining respiratory metabolism; similar to human PAC1 constituent of the PAC1-PAC2 complex involved in proteasome assembly
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm – 0.96 0.99 0.98 0.97 0.93 0.94 0.9 0.81 0.78 0.75 0.75 1.0 0.99 0.98 0.92 0.97 0.95 0.87 0.85 0.8 0.82 0.82 0.79
Endoplasmic Reticulum – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria – 0 0 0 0 0.19 0.08 0.14 0.32 0.29 0.36 0.38 0 0 0 0 0 0 0.05 0.05 0.09 0.05 0.06 0
Nucleus – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole – 0 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 4 7 2 4 5
Bud – 2 0 1 0 7 1 7 7 15 8 11 0 0 0 1 0 1 0 5 5 3 9 14
Bud Neck – 1 13 6 9 10 10 10 6 7 6 1 1 0 0 0 0 1 0 0 1 0 1 5
Bud Site – 0 0 1 0 1 0 0 0 0 1 3 0 0 0 0 0 0 – – – – – –
Cell Periphery – 6 7 8 2 1 6 6 6 5 2 6 1 3 0 5 4 4 0 2 10 1 2 3
Cytoplasm – 363 548 401 434 306 480 574 289 282 233 262 226 329 322 396 365 312 47 308 425 198 313 308
Endoplasmic Reticulum – 1 0 2 0 0 0 0 1 0 0 0 1 3 2 11 13 12 0 0 1 1 1 2
Endosome – 1 0 2 0 0 1 0 0 2 0 1 1 0 0 1 0 0 0 7 6 2 2 3
Golgi – 1 1 0 0 0 0 0 0 0 0 0 0 1 2 0 1 0 1 3 1 1 1 2
Mitochondria – 15 1 8 7 63 41 89 113 104 113 131 2 2 0 9 0 6 2 16 46 11 23 13
Nucleus – 1 1 0 2 5 0 5 3 1 2 2 0 0 1 9 5 10 0 2 0 0 0 1
Nuclear Periphery – 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0
Nucleolus – 0 1 0 0 1 0 2 0 0 1 3 0 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes – 0 0 0 1 0 1 2 0 1 0 3 0 0 0 0 0 0 0 0 0 1 0 0
SpindlePole – 0 7 4 10 0 17 13 12 18 12 18 0 1 0 0 0 0 0 2 6 3 7 8
Vac/Vac Membrane – 1 1 0 4 0 3 6 4 4 3 3 0 0 0 41 17 16 0 3 5 4 3 8
Unique Cell Count 379 556 408 449 330 509 639 357 363 311 349 227 334 327 429 378 329 55 363 532 242 382 390
Labelled Cell Count 394 580 434 469 394 560 715 441 439 381 444 232 339 328 475 405 362 55 363 532 242 382 390


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 4.1 4.9 4.3 5.2 3.4 4.4 4.1 3.9 3.9 3.7 3.8 4.5 4.5 4.8 7.6 8.3 7.2 4.1 3.9 4.4
Std Deviation (1e-4) – 1.4 1.3 1.0 1.7 1.5 2.4 1.3 1.7 1.4 1.4 1.2 1.5 1.2 1.6 1.9 1.8 1.6 1.7 1.4 1.9
Intensity Change (Log2) – – – -0.19 0.08 -0.53 -0.18 -0.27 -0.36 -0.35 -0.4 -0.39 -0.15 -0.12 -0.03 0.62 0.76 0.54 -0.27 -0.32 -0.16


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 7.2 4.7 4.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.4381 -0.1602 -0.2639 -0.8465 -0.3141 -0.1792 0.731 1.1027 1.0126 0.6164 0.4894 1.0987 3.2015 3.9237 3.1479 2.9582 3.3134 3.4664
Actin 0.0684 0.0003 0.0127 0.0069 0.0043 0.0015 0.0001 0.0004 0.0014 0.0002 0.0002 0.0003 0.007 0.0012 0.0013 0.0008 0.0003 0.0004
Bud 0.0099 0.0025 0.0004 0.0043 0.001 0.004 0.0001 0.0022 0.0018 0.0002 0.0008 0.0003 0.001 0.0004 0.0005 0.0003 0.0001 0.0001
Bud Neck 0.0065 0.0003 0.0016 0.0005 0.0009 0.0009 0.0001 0.0003 0.0002 0.0001 0.0001 0.0005 0.0017 0.0006 0.0003 0.0024 0.0001 0.0022
Bud Periphery 0.0031 0.0005 0.0009 0.0014 0.0013 0.0021 0.0001 0.0008 0.0018 0.0002 0.0025 0.0004 0.0018 0.0003 0.0004 0.0004 0.0002 0.0001
Bud Site 0.0062 0.0078 0.0008 0.0027 0.0015 0.0003 0.0003 0.0035 0.0009 0.0001 0.0001 0.0001 0.0008 0.0076 0.0016 0.0002 0.0001 0.0004
Cell Periphery 0.0008 0.0003 0.0001 0.0004 0.0002 0.0001 0 0.0001 0.0001 0 0.0001 0 0.0002 0.0001 0.0001 0.0001 0 0
Cytoplasm 0.1481 0.2168 0.2042 0.1231 0.1901 0.2925 0.2743 0.2461 0.2321 0.1993 0.2066 0.3084 0.2678 0.256 0.2549 0.1663 0.1922 0.3794
Cytoplasmic Foci 0.0196 0.0107 0.0075 0.0133 0.0147 0.0086 0.005 0.0152 0.0068 0.0047 0.0073 0.0079 0.0096 0.0102 0.0035 0.0089 0.0059 0.0057
Eisosomes 0.0009 0.0001 0.0002 0.0003 0.0002 0.0001 0.0001 0.0001 0.0001 0 0 0 0.0001 0.0001 0.0001 0.0001 0.0001 0
Endoplasmic Reticulum 0.0066 0.0018 0.0037 0.0015 0.0032 0.0022 0.0009 0.0009 0.0008 0.0007 0.0008 0.0007 0.0022 0.0006 0.0009 0.0007 0.0006 0.0008
Endosome 0.015 0.0072 0.0033 0.0049 0.0117 0.0035 0.0009 0.0027 0.0021 0.0013 0.0019 0.0013 0.0028 0.001 0.0007 0.0012 0.001 0.001
Golgi 0.0056 0.0014 0.0004 0.0004 0.0015 0.0005 0.0001 0.0003 0.0002 0.0001 0.0001 0.0001 0.0005 0.0002 0.0001 0.0002 0.0001 0.0001
Lipid Particles 0.0101 0.0003 0.0007 0.0004 0.0022 0.0014 0.0002 0.0001 0.0002 0.0001 0.0001 0.0001 0.0004 0.0001 0.0002 0.0009 0.0001 0.0001
Mitochondria 0.0035 0.0008 0.0005 0.0008 0.0025 0.001 0.0003 0.0006 0.0014 0.0003 0.0007 0.0002 0.0008 0.0002 0.0002 0.0003 0.0002 0.0001
None 0.6415 0.7293 0.748 0.8244 0.7261 0.6639 0.7135 0.7098 0.7404 0.7862 0.7722 0.6719 0.6941 0.7117 0.732 0.813 0.7951 0.6054
Nuclear Periphery 0.0091 0.0012 0.0014 0.0011 0.0118 0.0021 0.0004 0.0007 0.0007 0.0009 0.0004 0.0006 0.0019 0.0003 0.0005 0.0004 0.0004 0.0003
Nucleolus 0.0063 0.0007 0.0006 0.0019 0.0021 0.0004 0.0002 0.0006 0.0003 0.0001 0.0002 0.0001 0.0002 0.0005 0.0001 0.0002 0.0001 0.0001
Nucleus 0.0127 0.0092 0.0029 0.0041 0.012 0.0066 0.0019 0.0052 0.0036 0.0035 0.002 0.004 0.0022 0.0034 0.0011 0.0008 0.0011 0.0023
Peroxisomes 0.013 0.0002 0.0005 0.0025 0.0008 0.001 0.0001 0.0043 0.0022 0.0001 0.0001 0.0002 0.0025 0.0009 0.0001 0.0015 0.0002 0.0001
Punctate Nuclear 0.0083 0.0068 0.0087 0.004 0.0081 0.0064 0.001 0.0046 0.002 0.001 0.0008 0.0025 0.0013 0.0037 0.0009 0.0008 0.0016 0.001
Vacuole 0.0037 0.0016 0.0008 0.0009 0.0027 0.0008 0.0005 0.0013 0.0008 0.0007 0.0025 0.0004 0.0008 0.0007 0.0005 0.0005 0.0005 0.0003
Vacuole Periphery 0.001 0.0002 0.0002 0.0002 0.0013 0.0002 0.0001 0.0001 0.0001 0.0001 0.0004 0.0001 0.0003 0.0001 0.0001 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 20.5809 21.3655 24.662 30.8965 23.241 25.2143 24.6031 26.7307 30.2319 26.6134
Translational Efficiency 2.2148 1.7063 1.8502 1.2518 1.569 2.2027 2.0818 1.9244 1.7085 1.7433

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
57 1331 188 1986 2471 1894 1747 1690 2528 3225 1935 3676

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 731.30 643.74 867.40 747.72 658.62 736.72 814.68 812.78 660.26 698.35 819.80 777.63
Standard Deviation 190.81 89.55 108.51 156.59 72.91 85.01 119.95 129.33 78.31 98.23 119.91 148.28
Intensity Change Log 2 — -0.183985 0.246234 0.032035 — 0.161670 0.306787 0.303419 — -0.009853 0.275244 0.167007

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000830 0.000197 0.000449 0.000310 0.000069 0.000899 0.000220 0.000472 0.000086 0.000609 0.000243 0.000384
Bud Neck 0.062697 0.023106 0.002078 0.010379 0.014190 0.024450 0.004477 0.011358 0.015284 0.023895 0.004243 0.010829
Bud Site 0.034173 0.008453 0.001376 0.024225 0.002277 0.017587 0.007772 0.029346 0.002996 0.013817 0.007151 0.026579
Cell Periphery 0.000453 0.000135 0.000221 0.000258 0.000142 0.000201 0.000118 0.000262 0.000149 0.000174 0.000128 0.000260
Cytoplasm 0.164420* 0.470444* 0.152524* 0.420452* 0.518560* 0.509885* 0.421038* 0.449557* 0.510575* 0.493607* 0.394950* 0.433833*
Cytoplasmic Foci 0.109987 0.237119* 0.027024 0.023335 0.119281 0.125088 0.008420 0.014139 0.119072 0.171325 0.010227 0.019107
Eisosomes 0.000178 0.000110 0.000102 0.000052 0.000119 0.000106 0.000026 0.000044 0.000120 0.000108 0.000033 0.000049
Endoplasmic Reticulum 0.012330 0.000821 0.006466 0.001751 0.000404 0.000614 0.002443 0.001385 0.000673 0.000700 0.002834 0.001583
Endosome 0.057161 0.014327 0.002760 0.004703 0.002563 0.006281 0.001640 0.004847 0.003794 0.009602 0.001749 0.004769
Golgi 0.009990 0.003054 0.000096 0.000708 0.001132 0.003414 0.000162 0.000718 0.001331 0.003265 0.000155 0.000713
Lipid Particles 0.014165 0.006689 0.003569 0.001372 0.005167 0.003747 0.000776 0.000997 0.005370 0.004961 0.001047 0.001200
Mitochondria 0.014146 0.006901 0.000430 0.001930 0.003512 0.010221 0.000694 0.002377 0.003752 0.008851 0.000668 0.002135
Mitotic Spindle 0.014931 0.001348 0.000426 0.024007 0.001795 0.007072 0.007693 0.020799 0.002091 0.004710 0.006987 0.022532
None 0.007497 0.005728 0.005338 0.006025 0.003888 0.003152 0.007843 0.008564 0.003970 0.004215 0.007600 0.007192
Nuclear Periphery 0.001816 0.000494 0.001435 0.001734 0.000646 0.000458 0.001656 0.001298 0.000673 0.000473 0.001635 0.001534
Nuclear Periphery Foci 0.009395 0.000627 0.000911 0.000506 0.000147 0.000231 0.000752 0.000429 0.000356 0.000395 0.000767 0.000471
Nucleolus 0.016549 0.002028 0.001377 0.000752 0.000895 0.000918 0.000535 0.001389 0.001248 0.001376 0.000616 0.001045
Nucleus 0.316728* 0.154522* 0.744122* 0.397732* 0.307773* 0.251737* 0.489582* 0.383964* 0.307975* 0.211615* 0.514313* 0.391402*
Peroxisomes 0.012441 0.009589 0.000503 0.000601 0.003415 0.007848 0.000142 0.000638 0.003618 0.008567 0.000177 0.000618
Vacuole 0.124854 0.052262 0.048603 0.077518 0.013695 0.025128 0.043671 0.065531 0.016201 0.036326 0.044151 0.072007
Vacuole Periphery 0.015260 0.002048 0.000189 0.001650 0.000330 0.000961 0.000340 0.001886 0.000667 0.001409 0.000325 0.001759

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.34 0.10 1.90 -2.45 4.42 -2.72 -6.73 -5.23 1.37 -2.01 -2.91 -7.80 -6.92 1.23 -0.64
Bud Neck 1.94 2.94 2.65 6.47 -5.05 -5.27 7.20 1.96 6.92 -5.43 -5.19 7.91 3.64 9.67 -6.38
Bud Site 1.96 2.41 1.13 -4.87 -7.96 -8.45 -4.04 -8.65 -1.39 -5.98 -9.19 -3.26 -11.25 -3.37 -7.71
Cell Periphery 4.07 2.69 2.99 -3.38 0.69 -4.79 3.00 -2.72 0.46 -3.92 -2.69 2.47 -3.69 -1.79 -4.88
Cytoplasm -9.95 1.51 -6.56 10.62 -16.61 0.96 18.39 14.86 13.07 -2.78 2.33 20.67 18.62 17.48 -4.87
Cytoplasmic Foci -6.56 4.90 4.98 37.06 -0.06 -1.16 34.26 32.67 29.43 -4.00 -11.24 34.19 31.83 44.82 -7.65
Eisosomes 2.96 2.47 5.43 10.81 6.32 1.06 7.87 6.70 10.62 -5.18 1.09 7.36 6.55 14.45 -4.01
Endoplasmic Reticulum 3.14 0.32 2.62 -11.85 6.67 -1.91 -17.95 -15.12 -11.09 5.50 -0.27 -16.50 -14.71 -16.21 8.02
Endosome 2.90 3.68 3.68 9.32 -0.01 -5.66 3.23 -1.07 3.63 -2.51 -8.44 4.32 0.61 9.12 -3.82
Golgi 1.27 1.83 1.76 6.08 -2.34 -3.19 4.05 2.44 4.38 -1.64 -3.80 4.44 3.14 6.47 -2.62
Lipid Particles 2.20 3.16 3.85 11.59 5.00 2.38 9.03 8.90 6.43 -0.75 0.75 8.96 9.00 12.00 -0.03
Mitochondria 1.50 2.93 2.70 5.38 -5.28 -4.57 6.18 3.16 5.94 -3.22 -4.96 6.69 4.31 7.76 -5.15
Mitotic Spindle 1.47 1.52 -0.83 -8.07 -8.48 -3.73 -5.38 -7.13 -4.54 -3.05 -2.42 -5.00 -10.12 -8.49 -5.05
None 0.61 1.03 0.86 1.00 -0.62 1.17 -3.57 -3.66 -4.13 -0.55 -0.20 -3.24 -2.77 -2.41 0.62
Nuclear Periphery 2.24 -0.72 -1.57 -18.63 -2.47 2.75 -19.74 -12.98 -14.70 2.01 3.13 -20.13 -20.13 -24.09 -0.30
Nuclear Periphery Foci 1.86 1.62 1.82 -0.87 2.53 -0.82 -11.73 -5.41 -3.45 3.48 -0.34 -6.13 -3.26 -3.20 4.17
Nucleolus 3.04 3.23 3.36 6.84 2.55 0.54 3.93 -0.07 -0.42 -2.18 -0.31 4.60 2.61 3.58 -2.15
Nucleus 3.90 -8.58 -2.04 -31.49 15.39 7.12 -22.59 -11.58 -17.30 9.41 14.48 -25.60 -14.47 -31.75 13.93
Peroxisomes 0.71 3.36 3.37 10.85 0.29 -5.14 8.86 7.97 9.66 -3.28 -7.19 9.29 8.55 14.27 -5.12
Vacuole 2.73 0.98 -0.49 -15.84 -3.13 -8.53 -19.69 -23.39 -20.25 -5.80 -13.61 -19.81 -33.87 -26.49 -8.72
Vacuole Periphery 2.46 2.81 2.64 2.39 -3.04 -3.18 1.03 -2.31 -0.31 -2.51 -3.50 2.87 -1.67 1.25 -3.76
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in 20S proteasome assembly; forms a heterodimer with Add66p that binds to proteasome precursors; interaction with Pba1p-Add66p may affect function of the mature proteasome and its role in maintaining respiratory metabolism; similar to human PAC1 constituent of the PAC1-PAC2 complex involved in proteasome assembly
Localization
Cell Percentages cytoplasm (25%), nucleus (17%), mixed (47%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Pba1

Pba1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pba1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available