Standard name
Human Ortholog
Description Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase; GSY2 has a paralog, GSY1, that arose from the whole genome duplication; relocalizes from cytoplasm to plasma membrane upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0.11 0.14 – 0.25 0.25 0.18 0.26 0 0.09 0.14 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0.09 0.07 0.08 0.09 0 0 0 0 0 0 0.06 0.05 0 0 0.07 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0.05 – 0.09 0.11 0.05 0.09 0 0 0.07 0 0.05 0 0 0 0 0 0 0
Cytoplasm 0.98 0.94 0.97 0.95 0.9 0.66 0.56 – 0.29 0.27 0.16 0.19 0.9 0.76 0.72 0.91 0.92 0.82 0.87 0.8 0.84 0.83 0.76 0.78
Endoplasmic Reticulum 0 0 0 0 0 0.05 0.11 – 0 0.09 0.07 0.15 0 0.06 0.06 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0.05 0.06 0 0.1 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.16 0.14 – 0.4 0.35 0.55 0.24 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.05 0 0 0.08 0.11 0.12 – 0.11 0.14 0.17 0.18 0.06 0.06 0 0 0.08 0.13 0 0 0 0.05 0.05 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 8 9 66 109 – 153 158 110 153 1 24 34 0 0 0 1 3 2 0 3 1
Bud 0 0 2 4 6 14 26 – 56 45 47 54 4 9 9 1 0 0 8 11 15 5 16 5
Bud Neck 0 0 2 2 1 2 0 – 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 0
Bud Site 0 0 0 1 0 2 1 – 7 2 3 1 1 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 4 5 7 23 41 – 52 68 29 56 0 10 17 4 5 2 0 1 1 0 0 0
Cytoplasm 129 210 465 412 452 396 439 – 179 168 97 116 211 201 175 90 94 37 117 190 411 143 175 164
Endoplasmic Reticulum 0 2 10 5 3 32 83 – 26 58 43 88 1 17 15 3 3 1 0 3 1 3 6 6
Endosome 0 1 0 0 3 12 12 – 16 13 6 15 3 4 2 2 0 0 0 4 3 1 0 0
Golgi 1 1 1 2 1 3 13 – 33 35 20 58 0 10 10 0 1 0 0 1 2 0 1 2
Mitochondria 0 2 0 8 15 99 111 – 242 219 338 141 2 5 5 4 2 2 0 2 14 4 4 6
Nucleus 0 1 4 3 1 8 12 – 3 8 7 6 0 1 0 1 1 1 0 5 4 1 2 2
Nuclear Periphery 0 0 0 0 1 1 4 – 2 5 8 5 1 1 0 0 0 0 0 0 2 0 0 0
Nucleolus 0 0 2 0 2 1 5 – 2 3 12 5 1 1 1 1 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 11 7 – 29 10 1 5 2 3 5 0 0 0 0 0 0 0 0 1
SpindlePole 0 0 0 2 3 4 6 – 7 2 3 10 0 1 2 0 0 0 2 2 12 1 2 2
Vac/Vac Membrane 1 11 3 12 42 65 93 – 69 84 108 107 15 15 3 3 8 6 1 8 9 8 11 13
Unique Cell Count 131 224 478 432 503 602 780 611 622 618 596 234 263 242 99 102 45 135 240 489 173 231 212
Labelled Cell Count 132 228 494 464 546 739 962 876 878 832 820 242 302 278 109 114 49 135 240 489 173 231 212


Cytoplasm, Nucleus, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.2 9.0 6.5 5.8 7.2 6.5 7.5 – 8.0 8.4 7.8 9.1 6.9 10.5 11.5 10.2 9.6 9.4 5.8 6.5 7.1
Std Deviation (1e-4) 2.4 4.1 1.5 1.5 1.9 1.9 2.1 – 2.7 2.6 2.5 2.9 2.0 3.5 3.9 4.2 2.7 2.6 1.7 2.5 2.8
Intensity Change (Log2) – – – -0.18 0.14 -0.01 0.2 – 0.29 0.36 0.25 0.47 0.07 0.68 0.82 0.65 0.56 0.53 -0.18 0.0 0.12

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 7.3 8.4 – 11.7 11.8 9.6 11.8 0 6.4 8.2 0 0 0
Bud 0 0 2.6 3.4 – 6.4 5.5 5.7 6.3 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0.8 3.1 4.1 – 5.7 6.7 3.7 6.1 0 0 4.7 0 0 0
Cytoplasm -1.5 -4.7 -12.8 -15.7 – -22.6 -23.4 -26.8 -25.4 -4.1 -9.0 -10.1 -3.0 -2.5 -4.9
Endoplasmic Reticulum -1.1 -2.0 2.7 5.6 – 2.0 4.9 3.7 7.2 0 3.0 2.8 0 0 0
Endosome 0 0 3.1 0 – 3.6 3.2 0 3.5 0 0 0 0 0 0
Golgi 0 0 0 2.4 – 4.9 5.0 3.6 6.8 0 0 0 0 0 0
Mitochondria 0 3.8 9.3 8.6 – 15.6 14.5 19.4 11.4 0 0 0 0 0 0
Nucleus 0 0 0.8 1.1 – 0 0.7 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 2.2 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 4.8 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 2.5 5.8 6.8 7.3 – 7.0 7.8 9.2 9.3 4.6 4.3 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.4592 6.5276 5.1009 4.6468 4.1725 6.0527 6.6363 6.4148 5.3232 4.2167 4.3574 5.5207 8.8368 9.6254 8.2633 7.4699 7.6395 7.9929
Actin 0.0187 0.0104 0.013 0.0016 0.0076 0.0072 0.0059 0.0194 0.013 0.0088 0.0682 0.0067 0.0113 0.0328 0.0156 0.0139 0.0002 0.0116
Bud 0.0016 0.0123 0.0049 0.0137 0.0066 0.0016 0.0003 0.0084 0.0034 0.0039 0.0076 0.0019 0.0026 0.0042 0.0016 0.0053 0.0001 0.0004
Bud Neck 0.007 0.0007 0.0013 0.0009 0.002 0.0043 0.0005 0.0005 0.0019 0.0013 0.0016 0.0035 0.0032 0.001 0.0038 0.0007 0.0006 0.0023
Bud Periphery 0.0016 0.0072 0.0029 0.0051 0.0091 0.0017 0.0002 0.004 0.0026 0.0039 0.0061 0.0018 0.0021 0.0031 0.0008 0.0033 0 0.0003
Bud Site 0.0065 0.0094 0.0052 0.0007 0.0023 0.001 0.0012 0.0122 0.0133 0.0006 0.0027 0.0003 0.0036 0.0136 0.0068 0.0007 0 0.0005
Cell Periphery 0.0009 0.0006 0.0006 0.0001 0.0007 0.0002 0.0002 0.0003 0.0007 0.0002 0.0003 0.0001 0.0005 0.0136 0.0002 0.0001 0 0.0061
Cytoplasm 0.78 0.884 0.8544 0.8797 0.8548 0.8951 0.8607 0.8849 0.8693 0.8615 0.8226 0.91 0.8526 0.8734 0.8941 0.9034 0.9792 0.928
Cytoplasmic Foci 0.0193 0.0063 0.0102 0.0035 0.007 0.0077 0.0271 0.0123 0.0174 0.0111 0.0164 0.0141 0.0189 0.0054 0.0286 0.0151 0.0028 0.0126
Eisosomes 0.0001 0 0.0001 0 0.0001 0 0.0001 0 0.0001 0 0.0002 0 0.0001 0.0051 0.0001 0 0 0.0001
Endoplasmic Reticulum 0.0066 0.003 0.0064 0.003 0.0085 0.0041 0.0028 0.0017 0.0033 0.0075 0.0036 0.0027 0.0044 0.0029 0.0034 0.0077 0.0009 0.0031
Endosome 0.0183 0.0036 0.0144 0.0024 0.0206 0.007 0.0065 0.0034 0.0054 0.011 0.0202 0.0055 0.0194 0.002 0.0085 0.0107 0.0008 0.0024
Golgi 0.004 0.0003 0.0046 0.0001 0.0041 0.0006 0.0015 0.0014 0.0007 0.0008 0.0049 0.0003 0.0034 0.0013 0.0039 0.0017 0 0.0004
Lipid Particles 0.0079 0.0002 0.0032 0 0.0037 0.0004 0.0041 0.0001 0.0012 0.0003 0.0021 0.0001 0.012 0.0002 0.0029 0.0007 0 0.0007
Mitochondria 0.0073 0.0005 0.0081 0.0005 0.0079 0.0006 0.0081 0.0013 0.0005 0.0012 0.0031 0.0005 0.0021 0.0005 0.0026 0.0006 0.0001 0.0051
None 0.0253 0.0401 0.0268 0.0236 0.0352 0.0225 0.0323 0.0195 0.0329 0.0672 0.008 0.0165 0.007 0.0223 0.0064 0.0242 0.0072 0.0032
Nuclear Periphery 0.0205 0.0031 0.0055 0.0066 0.005 0.0056 0.004 0.0021 0.0031 0.0034 0.007 0.0075 0.0096 0.0019 0.0021 0.003 0.0009 0.0031
Nucleolus 0.0009 0.0001 0.0027 0.0002 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001 0.0005 0.0001 0.0003 0.0002 0.0003 0 0 0
Nucleus 0.0536 0.0139 0.0194 0.0501 0.0159 0.0339 0.0361 0.0179 0.0233 0.009 0.0104 0.0204 0.0328 0.0134 0.0109 0.0051 0.0064 0.0168
Peroxisomes 0.005 0.0002 0.0069 0.0001 0.0005 0.0002 0.0031 0.0011 0.0025 0.0012 0.002 0.0004 0.005 0.0002 0.0025 0.0004 0 0.0002
Punctate Nuclear 0.0096 0.001 0.0046 0.0054 0.0013 0.0027 0.0035 0.0081 0.0032 0.0027 0.0096 0.0038 0.0056 0.0011 0.0026 0.0014 0.0004 0.0021
Vacuole 0.0035 0.0025 0.004 0.0024 0.0055 0.0027 0.0013 0.001 0.0018 0.0033 0.0024 0.0025 0.0028 0.0018 0.0017 0.0017 0.0003 0.0005
Vacuole Periphery 0.0018 0.0003 0.0008 0.0004 0.0013 0.0006 0.0003 0.0002 0.0003 0.0008 0.0007 0.0014 0.0007 0.0002 0.0005 0.0004 0.0001 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.6798 9.7799 9.6762 38.0284 31.0709 26.0338 11.8897 16.5262 43.7964 43.983
Translational Efficiency 0.6398 0.2236 0.497 1.0281 0.9278 0.5537 0.6296 0.6009 0.7643 0.6828

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
460 1136 613 1020 1861 2238 1393 231 2321 3374 2006 1251

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 704.72 909.92 2454.78 1377.63 746.93 939.07 1111.20 1434.96 738.56 929.26 1521.78 1388.22
Standard Deviation 126.13 181.16 618.53 334.52 120.25 196.86 282.58 308.25 122.59 192.21 745.27 330.57
Intensity Change Log 2 — 0.368690 1.800472 0.967066 — 0.330260 0.573074 0.941966 — 0.349044 1.296605 0.954206

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000131 0.000324 0.170457 0.253194 0.000350 0.000220 0.013416 0.267068 0.000307 0.000255 0.061405 0.255756
Bud Neck 0.009129 0.007372 0.040942 0.013675 0.009827 0.005402 0.005684 0.016573 0.009689 0.006065 0.016458 0.014210
Bud Site 0.007755 0.012712 0.265074 0.156566 0.009718 0.011876 0.029385 0.229722 0.009329 0.012157 0.101407 0.170074
Cell Periphery 0.000182 0.000117 0.106160 0.002994 0.000225 0.000074 0.000450 0.006690 0.000216 0.000088 0.032753 0.003676
Cytoplasm 0.625791 0.666004 0.094892 0.224645 0.624592 0.760008 0.618729 0.210572 0.624830 0.728357 0.458653 0.222047
Cytoplasmic Foci 0.193636 0.142366 0.039079 0.049624 0.154197 0.094354 0.021563 0.050556 0.162013 0.110519 0.026916 0.049796
Eisosomes 0.000122 0.000057 0.014265 0.001615 0.000106 0.000024 0.000085 0.006340 0.000109 0.000035 0.004418 0.002488
Endoplasmic Reticulum 0.002283 0.001130 0.022110 0.004778 0.000965 0.000539 0.001875 0.005068 0.001227 0.000738 0.008059 0.004831
Endosome 0.011753 0.015719 0.009036 0.007470 0.008108 0.010265 0.001719 0.008205 0.008830 0.012101 0.003955 0.007605
Golgi 0.001109 0.003111 0.013970 0.009807 0.001192 0.002854 0.000288 0.017788 0.001175 0.002941 0.004469 0.011281
Lipid Particles 0.007015 0.002632 0.108097 0.010344 0.005237 0.001332 0.001729 0.008864 0.005589 0.001770 0.034233 0.010071
Mitochondria 0.000936 0.002653 0.001122 0.008858 0.002310 0.003261 0.000387 0.001216 0.002037 0.003056 0.000611 0.007447
Mitotic Spindle 0.000130 0.003907 0.003328 0.077851 0.002128 0.006940 0.014823 0.029125 0.001732 0.005919 0.011311 0.068854
None 0.003864 0.006210 0.001091 0.001860 0.005186 0.003847 0.007761 0.003450 0.004924 0.004643 0.005722 0.002154
Nuclear Periphery 0.000321 0.000229 0.000583 0.000406 0.000257 0.000139 0.000721 0.000264 0.000269 0.000170 0.000679 0.000380
Nuclear Periphery Foci 0.002495 0.001859 0.003052 0.002225 0.000954 0.000965 0.003006 0.003091 0.001260 0.001266 0.003020 0.002385
Nucleolus 0.000603 0.000882 0.000103 0.000138 0.000635 0.000365 0.000176 0.000078 0.000629 0.000539 0.000154 0.000127
Nucleus 0.066451 0.056480 0.055033 0.052898 0.115474 0.042090 0.198518 0.038999 0.105758 0.046935 0.154671 0.050331
Peroxisomes 0.002210 0.003594 0.000984 0.016564 0.002454 0.001814 0.002979 0.010853 0.002406 0.002414 0.002369 0.015510
Vacuole 0.063030 0.071374 0.049219 0.098526 0.055344 0.052427 0.076197 0.085097 0.056867 0.058806 0.067953 0.096046
Vacuole Periphery 0.001054 0.001268 0.001404 0.005962 0.000742 0.001203 0.000510 0.000381 0.000804 0.001225 0.000783 0.004932

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.22 -15.59 -11.42 -11.39 5.46 0.89 -4.25 -6.17 -6.18 -5.68 0.44 -14.56 -12.95 -12.96 -4.75
Bud Neck 1.05 -13.15 -2.08 -3.99 13.02 4.52 3.35 -2.56 -5.16 -4.59 4.19 -5.72 -2.85 -7.81 2.90
Bud Site -1.87 -21.48 -14.43 -13.97 13.23 -1.22 -5.04 -8.57 -8.43 -7.38 -1.88 -18.13 -17.03 -16.75 -0.27
Cell Periphery 4.66 -13.08 -6.14 -6.46 12.87 3.88 -2.76 -5.31 -5.62 -5.00 4.07 -12.03 -7.72 -8.49 11.25
Cytoplasm -2.49 33.75 25.14 33.99 -11.43 -16.66 10.70 18.77 26.24 12.98 -14.30 25.01 39.44 53.29 13.44
Cytoplasmic Foci 5.35 15.35 17.58 18.11 1.07 12.03 32.44 12.34 4.71 -6.33 11.62 33.78 27.35 18.56 -5.49
Eisosomes 6.22 -5.68 -3.74 -4.29 5.41 8.20 3.12 -1.92 -2.00 -1.96 8.85 -5.53 -3.48 -3.83 3.92
Endoplasmic Reticulum 0.82 -5.84 -0.73 -5.38 6.35 3.10 -8.48 -3.44 -4.11 -1.18 1.64 -7.77 -4.80 -7.63 4.84
Endosome -2.53 3.28 7.38 9.40 3.59 -2.09 11.56 2.83 3.98 -2.12 -3.88 9.61 8.26 10.74 -0.64
Golgi -2.75 -5.15 -1.55 0.51 4.06 -3.21 7.99 -1.14 -0.68 -1.41 -4.20 -3.89 -1.88 -0.11 0.44
Lipid Particles 2.59 -11.63 -1.62 -9.95 11.48 6.50 4.94 -3.87 -7.17 -6.44 6.59 -9.90 -5.36 -12.90 7.97
Mitochondria -1.64 -0.69 -1.63 0.12 -1.45 -0.92 4.32 3.65 3.20 -0.30 -1.28 3.92 -0.01 0.96 -1.96
Mitotic Spindle -3.31 -4.56 -12.12 -11.31 -11.16 -3.15 -7.28 -4.53 -3.98 -2.68 -3.63 -7.71 -12.56 -11.70 -9.88
None -1.73 3.72 1.65 2.93 -5.51 2.39 -1.36 0.75 -0.82 1.84 0.67 0.47 3.65 3.16 4.74
Nuclear Periphery 1.26 -6.51 -12.41 -17.16 -6.99 4.34 -21.36 -7.78 -8.95 4.15 4.03 -22.19 -17.79 -19.55 -2.29
Nuclear Periphery Foci 0.48 -1.24 -2.28 -7.82 -2.67 -0.30 -8.35 -5.05 -5.02 -2.45 -0.16 -7.63 -9.67 -11.09 -3.45
Nucleolus -1.61 4.18 3.22 3.02 -2.57 4.29 8.11 8.21 3.68 1.24 0.30 9.15 7.72 3.63 -2.24
Nucleus 1.89 -4.92 -7.56 -10.03 -0.02 21.41 -18.73 2.85 -5.36 14.25 19.95 -16.69 -0.45 -13.56 13.94
Peroxisomes -1.69 2.61 -2.71 -1.41 -4.45 1.45 0.96 -1.24 -1.62 -1.56 0.09 1.74 -2.93 -3.05 -3.81
Vacuole -2.11 -1.61 -23.44 -22.72 -21.98 0.41 -15.76 -11.22 -11.29 -6.02 -1.66 -14.96 -28.28 -27.78 -18.27
Vacuole Periphery -0.66 -0.40 -0.60 -0.33 -0.46 -2.01 2.43 5.30 4.55 0.51 -2.38 1.65 -0.80 -0.05 -1.24
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase; GSY2 has a paralog, GSY1, that arose from the whole genome duplication; relocalizes from cytoplasm to plasma membrane upon DNA replication stress
Localization
Cell Percentages cytoplasm (65%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Gsy2

Gsy2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gsy2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available