Standard name
Human Ortholog
Description Protein component of the synaptonemal complex axial elements; involved in chromosome segregation during the first meiotic division; critical for coupling checkpoint signaling to SC formation; promotes interhomolog recombination by phosphorylating Hop1p; also interacts with Mec3p and Ddc1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.98 0.99 0.99 0.98 0.96 0.96 0.96 0.89 – 0.79 0.81 0.98 0.99 0.99 0.57 0.59 0.57 0.89 0.91 0.77 0.85 0.76 0.69
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.1 0.11 0.06 0.28 – 0.33 0.21 0.08 0 0 0 0 0 0 0 0.07 0.06 0.09 0.09
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.2 0.21 0.18 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.28 0.28 0.3 0 0 0 0 0 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 – 0 0 0 0 0 1 1 0 1 1 3 0 3 3
Bud 0 1 0 0 1 2 2 2 4 – 2 4 0 0 0 0 0 0 1 1 7 0 6 7
Bud Neck 1 1 10 7 14 6 5 10 8 – 1 8 0 0 0 0 2 0 0 0 1 0 3 2
Bud Site 0 0 0 0 0 0 0 0 1 – 1 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 2 1 2 2 0 4 3 1 – 0 0 0 1 2 1 1 0 1 1 5 0 3 3
Cytoplasm 189 302 492 332 503 328 455 362 258 – 142 208 114 331 321 232 198 169 174 280 338 57 252 154
Endoplasmic Reticulum 0 0 0 0 0 0 1 0 0 – 0 0 0 2 0 20 12 17 0 0 3 0 5 4
Endosome 0 0 0 0 0 1 0 0 0 – 0 1 0 0 0 19 5 11 0 3 4 0 2 2
Golgi 0 0 1 0 0 0 0 1 0 – 0 0 0 0 0 0 1 1 0 0 3 0 0 0
Mitochondria 2 9 2 4 6 34 52 21 80 – 59 55 9 0 0 6 8 8 5 8 29 3 29 20
Nucleus 1 0 5 5 2 1 4 5 3 – 3 7 0 0 0 81 71 52 0 0 1 0 1 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 2 0 0 0
Nucleolus 0 1 0 0 0 0 0 0 0 – 0 1 0 1 1 0 0 0 0 0 1 0 1 0
Peroxisomes 0 0 1 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 2 0 3 3 5 5 0 – 2 6 0 0 0 2 1 2 0 4 7 0 5 0
Vac/Vac Membrane 1 0 1 1 1 1 1 0 3 – 1 3 0 0 1 115 96 88 4 3 4 1 12 17
Unique Cell Count 193 307 498 336 511 340 474 376 289 180 258 116 333 323 410 338 297 196 308 438 68 333 222
Labelled Cell Count 197 316 515 351 532 376 529 410 358 211 296 123 335 325 478 396 348 196 308 438 68 333 222


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.6 4.0 4.8 4.3 4.9 3.8 4.2 4.5 3.4 – 3.1 3.6 4.1 4.2 4.3 6.4 6.6 6.1 4.0 3.9 4.4
Std Deviation (1e-4) 0.5 0.6 1.3 1.5 1.7 1.5 1.5 1.8 1.2 – 0.7 0.9 1.6 1.2 1.6 1.2 1.3 1.1 1.7 1.3 1.8
Intensity Change (Log2) – – – -0.13 0.03 -0.32 -0.2 -0.09 -0.51 – -0.64 -0.41 -0.21 -0.18 -0.14 0.42 0.46 0.35 -0.24 -0.29 -0.11

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 12.5 12.5 12.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.0128 1.5309 1.1406 0.5418 0.8498 1.1798 -0.3577 -0.4296 -0.3205 -0.1603 -0.5429 -0.7016 -1.1285 -1.2126 -1.3562 -1.1393 -1.199 -1.0311
Actin 0.0292 0.0002 0.0053 0.0001 0.0316 0.0034 0.0267 0.001 0.0066 0.0125 0.0033 0.0071 0.0458 0.0004 0.0025 0.0129 0.0215 0.0091
Bud 0.0028 0.011 0.0017 0 0.0014 0.0006 0.006 0.0061 0.0079 0.0031 0.0007 0.0038 0.0019 0.0024 0.0001 0.0012 0.0016 0.0014
Bud Neck 0.0088 0.0001 0.0011 0 0.025 0.0022 0.0032 0.0003 0.003 0.0019 0.0011 0.0026 0.0056 0.0008 0.0001 0.0002 0.0011 0.0011
Bud Periphery 0.0056 0.002 0.0028 0 0.0038 0.0017 0.0119 0.01 0.0159 0.0151 0.0009 0.007 0.0049 0.0036 0.0002 0.0029 0.0035 0.002
Bud Site 0.0133 0.0104 0.0112 0 0.0071 0.002 0.0088 0.0177 0.027 0.006 0.0126 0.0022 0.0036 0.0203 0.0003 0.0012 0.0024 0.0005
Cell Periphery 0.0007 0.0003 0.0009 0 0.0003 0.0002 0.0008 0.0006 0.0009 0.0003 0.0002 0.0002 0.0004 0.0004 0 0.0001 0.0002 0.0001
Cytoplasm 0.0266 0.0234 0.0455 0.0314 0.0283 0.0797 0.0847 0.1078 0.1005 0.1158 0.129 0.1572 0.0291 0.0541 0.0219 0.0208 0.0129 0.0388
Cytoplasmic Foci 0.0151 0.0016 0.0073 0.0049 0.0298 0.0133 0.0186 0.0049 0.014 0.0414 0.0145 0.0099 0.0104 0.0042 0.0046 0.0032 0.0062 0.007
Eisosomes 0.0016 0.0002 0.0006 0.0001 0.0004 0.0003 0.0004 0.0001 0.0003 0.0004 0.0001 0.0001 0.001 0.0001 0.0002 0.0002 0.0002 0.0001
Endoplasmic Reticulum 0.0024 0.0004 0.0021 0.0003 0.0017 0.0004 0.0049 0.0011 0.0022 0.0019 0.0026 0.0008 0.003 0.0004 0.0009 0.0009 0.0047 0.0011
Endosome 0.0142 0.0001 0.0037 0.0005 0.015 0.004 0.0172 0.001 0.0056 0.0416 0.0259 0.0019 0.0164 0.0005 0.0019 0.0041 0.006 0.0047
Golgi 0.0067 0 0.0022 0.0005 0.0078 0.0022 0.0054 0.0001 0.0013 0.018 0.0073 0.0007 0.0035 0.0001 0.0014 0.0013 0.0024 0.0013
Lipid Particles 0.0133 0.0001 0.0094 0.0074 0.0043 0.0095 0.0108 0.0002 0.0017 0.0131 0.0261 0.0006 0.0037 0.0002 0.0024 0.0013 0.0011 0.0012
Mitochondria 0.0211 0.0003 0.0083 0.0002 0.0369 0.0018 0.0057 0.0005 0.0064 0.0193 0.029 0.0028 0.0018 0.0008 0.0018 0.0042 0.0026 0.0058
None 0.8059 0.9484 0.8676 0.9267 0.7609 0.8596 0.7419 0.8407 0.7831 0.6816 0.7247 0.7941 0.8424 0.9012 0.9537 0.9326 0.8985 0.9129
Nuclear Periphery 0.0045 0.0002 0.0017 0.0001 0.0038 0.0016 0.0132 0.0007 0.0051 0.0019 0.0063 0.0007 0.0067 0.0007 0.0026 0.0052 0.019 0.0033
Nucleolus 0.0015 0.0001 0.0009 0.0001 0.0044 0.0009 0.0026 0.0004 0.0035 0.0013 0.0012 0.0004 0.0014 0.0008 0.0002 0.0006 0.0002 0.0004
Nucleus 0.0023 0.0004 0.002 0.0002 0.0235 0.0011 0.0143 0.0025 0.0043 0.0024 0.0027 0.0018 0.0048 0.0019 0.0006 0.002 0.0023 0.0021
Peroxisomes 0.0178 0.0001 0.0211 0.0269 0.0052 0.0088 0.0091 0.0003 0.0016 0.0069 0.0041 0.0014 0.0018 0.0003 0.0017 0.0015 0.0102 0.0014
Punctate Nuclear 0.0038 0.0004 0.0029 0.0003 0.0037 0.0056 0.0056 0.0025 0.0045 0.0105 0.0039 0.0037 0.0069 0.006 0.0024 0.0025 0.0008 0.0048
Vacuole 0.0018 0.0002 0.0011 0.0001 0.0034 0.001 0.0063 0.0015 0.0039 0.0039 0.0025 0.0006 0.0041 0.0005 0.0003 0.0007 0.0013 0.0006
Vacuole Periphery 0.001 0 0.0005 0 0.0017 0.0002 0.002 0.0002 0.0008 0.0009 0.0015 0.0001 0.0008 0.0001 0.0002 0.0006 0.0013 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1.3326 0.3971 3.2413 4.0906 2.5917 3.5517 3.4127 5.1487 3.8899 4.5343
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2114 1380 3279 1646 1249 1934 124 77 3363 3314 3403 1723

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 607.45 713.84 912.89 769.84 658.14 686.11 839.90 1066.17 626.28 697.66 910.23 783.08
Standard Deviation 68.49 90.22 130.93 103.38 74.41 94.36 90.03 119.56 74.86 93.66 130.39 120.82
Intensity Change Log 2 — 0.232835 0.587675 0.341793 — 0.060045 0.351823 0.695971 — 0.145565 0.469843 0.536764

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000061 0.000201 0.000087 0.001821 0.000065 0.000228 0.000177 0.000040 0.000063 0.000217 0.000090 0.001741
Bud Neck 0.007221 0.026638 0.011931 0.009610 0.010077 0.043367 0.001893 0.006457 0.008282 0.036401 0.011565 0.009469
Bud Site 0.002540 0.006749 0.008341 0.031631 0.002497 0.016202 0.008003 0.006079 0.002524 0.012266 0.008328 0.030489
Cell Periphery 0.000127 0.000115 0.000123 0.000153 0.000131 0.000156 0.000184 0.000138 0.000128 0.000139 0.000125 0.000153
Cytoplasm 0.545370 0.444574 0.253449 0.491386 0.503574 0.429654 0.183643 0.614488 0.529847 0.435867 0.250905 0.496887
Cytoplasmic Foci 0.050914 0.219693 0.000565 0.013862 0.138653 0.233689 0.017621 0.002932 0.083500 0.227861 0.001186 0.013374
Eisosomes 0.000049 0.000119 0.000008 0.000036 0.000095 0.000154 0.000087 0.000007 0.000066 0.000139 0.000011 0.000034
Endoplasmic Reticulum 0.000233 0.000588 0.000901 0.001919 0.000478 0.000517 0.002178 0.000204 0.000324 0.000547 0.000947 0.001842
Endosome 0.001883 0.019479 0.000216 0.002652 0.004052 0.020921 0.001732 0.000754 0.002689 0.020321 0.000271 0.002567
Golgi 0.000466 0.004043 0.000031 0.001743 0.000590 0.004347 0.000058 0.000067 0.000512 0.004220 0.000032 0.001668
Lipid Particles 0.001488 0.005588 0.000096 0.000876 0.004413 0.008235 0.002266 0.000369 0.002574 0.007132 0.000175 0.000854
Mitochondria 0.001599 0.009837 0.000961 0.004494 0.001345 0.013013 0.000440 0.002656 0.001505 0.011691 0.000942 0.004412
Mitotic Spindle 0.002407 0.003162 0.006761 0.029339 0.001506 0.008259 0.005895 0.005704 0.002072 0.006137 0.006730 0.028283
None 0.009355 0.003991 0.008898 0.005363 0.005529 0.003532 0.023682 0.008549 0.007934 0.003723 0.009437 0.005506
Nuclear Periphery 0.000421 0.000537 0.001753 0.001619 0.000534 0.000637 0.001009 0.000520 0.000463 0.000595 0.001726 0.001569
Nuclear Periphery Foci 0.000120 0.000360 0.000050 0.001196 0.000234 0.000290 0.000365 0.000024 0.000163 0.000319 0.000062 0.001144
Nucleolus 0.002082 0.001981 0.000326 0.000750 0.000849 0.001886 0.001533 0.000589 0.001624 0.001926 0.000370 0.000742
Nucleus 0.364267 0.171039 0.697250 0.325167 0.299533 0.136723 0.713749 0.280073 0.340225 0.151012 0.697851 0.323152
Peroxisomes 0.001985 0.012439 0.000037 0.001008 0.002959 0.013763 0.000363 0.000251 0.002347 0.013212 0.000049 0.000974
Vacuole 0.007044 0.066753 0.008099 0.073077 0.022531 0.062208 0.034982 0.069372 0.012796 0.064100 0.009079 0.072911
Vacuole Periphery 0.000366 0.002113 0.000116 0.002299 0.000354 0.002219 0.000142 0.000725 0.000362 0.002175 0.000117 0.002229

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.35 -1.89 -2.20 -1.86 -2.08 -6.85 -3.10 -0.74 4.72 2.75 -6.10 -3.15 -2.20 -1.80 -2.06
Bud Neck -9.46 -3.97 -1.45 9.14 3.09 -13.03 5.49 2.20 14.83 -3.39 -16.49 -3.35 -0.58 16.52 2.98
Bud Site -4.91 -4.20 -7.18 -5.19 -5.03 -8.84 -0.89 -1.57 2.86 -0.09 -9.86 -4.59 -7.36 -2.61 -5.00
Cell Periphery 1.58 2.32 0.43 -0.46 -1.21 -2.27 -2.66 2.92 3.82 4.12 -1.40 2.43 0.79 1.50 -0.89
Cytoplasm 10.89 47.38 17.26 5.11 -21.82 7.19 16.07 0.21 -2.50 -10.10 14.03 52.45 16.45 4.83 -23.22
Cytoplasmic Foci -27.99 26.99 20.15 36.26 -15.49 -13.50 20.84 27.27 44.61 3.79 -32.52 36.25 30.88 56.38 -14.48
Eisosomes -8.93 20.60 1.32 9.42 -23.59 -6.51 -0.72 12.57 20.10 8.85 -13.02 20.00 7.44 18.29 -20.15
Endoplasmic Reticulum -4.28 -13.42 -15.97 -14.21 -9.10 -0.39 -4.23 0.85 1.15 4.31 -3.63 -14.78 -15.93 -14.67 -7.98
Endosome -13.64 4.87 0.05 14.03 -10.80 -13.23 2.51 6.61 17.55 4.71 -19.62 8.22 2.79 21.47 -10.22
Golgi -5.09 3.02 -0.47 3.96 -1.42 -7.83 3.96 3.91 9.28 -0.35 -9.14 4.62 -0.35 5.85 -1.42
Lipid Particles -11.73 10.40 3.27 13.98 -22.44 -4.70 3.14 7.82 12.24 5.84 -10.23 11.49 7.47 15.49 -19.06
Mitochondria -6.53 0.99 -0.92 5.44 -1.83 -9.87 3.92 -0.53 8.62 -2.02 -11.37 1.31 -1.15 8.62 -1.90
Mitotic Spindle -0.49 -5.81 -6.84 -6.50 -3.36 -4.25 -1.16 -1.44 -0.69 -1.03 -3.73 -6.57 -7.26 -5.40 -3.46
None 5.33 1.00 4.81 -1.78 7.08 1.88 -1.76 -2.98 -4.45 0.86 6.07 -1.48 3.37 -3.47 6.62
Nuclear Periphery -1.98 -23.18 -21.28 -21.68 -4.68 -0.73 -6.24 -3.35 -2.28 2.05 -1.53 -26.10 -22.28 -17.32 -4.39
Nuclear Periphery Foci -4.33 0.86 -3.88 -2.68 -4.02 -1.01 -3.29 6.34 4.49 4.73 -3.84 1.69 -3.69 -2.88 -3.91
Nucleolus 0.16 4.41 3.65 6.26 -2.20 -6.12 -1.71 2.43 7.26 2.77 -1.22 4.85 3.72 8.11 -1.98
Nucleus 24.26 -50.07 -2.41 -24.67 42.47 18.93 -14.27 -2.22 -8.69 9.01 33.42 -60.51 -5.47 -31.97 43.50
Peroxisomes -8.46 3.72 2.70 10.58 -3.54 -9.90 4.68 5.03 14.40 2.39 -13.28 5.90 4.47 17.33 -3.49
Vacuole -20.89 -5.42 -27.12 -13.14 -25.98 -14.48 -4.23 -3.76 -1.72 -0.46 -26.97 -1.47 -26.19 -14.81 -25.60
Vacuole Periphery -5.62 2.55 -1.86 2.61 -2.79 -5.63 3.44 0.49 5.38 -0.77 -7.66 3.71 -1.91 3.24 -2.81
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein component of the synaptonemal complex axial elements; involved in chromosome segregation during the first meiotic division; critical for coupling checkpoint signaling to SC formation; promotes interhomolog recombination by phosphorylating Hop1p; also interacts with Mec3p and Ddc1p
Localization
Cell Percentages cytoplasm (23%), nucleus (7%), mixed (60%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Red1

Red1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Red1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available