| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | 0 | 2 | 0 | 0 | 0 | 3 |
| Bud | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | 3 | 7 | 0 | 3 | 4 | 6 |
| Bud Neck | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 2 | 0 | – | – | – | 0 | 0 | 0 | 1 | 1 | 4 |
| Bud Site | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | – | – | – | – | – | – |
| Cell Periphery | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| Cytoplasm | 27 | 26 | – | – | – | – | – | – | – | – | – | – | 24 | 85 | 114 | – | – | – | 16 | 4 | 0 | 15 | 27 | 38 |
| Endoplasmic Reticulum | 0 | 2 | – | – | – | – | – | – | – | – | – | – | 0 | 2 | 1 | – | – | – | 0 | 1 | 0 | 1 | 0 | 1 |
| Endosome | 1 | 1 | – | – | – | – | – | – | – | – | – | – | 0 | 1 | 9 | – | – | – | 1 | 2 | 0 | 2 | 2 | 6 |
| Golgi | 0 | 1 | – | – | – | – | – | – | – | – | – | – | 0 | 1 | 1 | – | – | – | 0 | 1 | 0 | 0 | 0 | 2 |
| Mitochondria | 62 | 6 | – | – | – | – | – | – | – | – | – | – | 1 | 2 | 1 | – | – | – | 4 | 2 | 0 | 2 | 10 | 20 |
| Nucleus | 98 | 143 | – | – | – | – | – | – | – | – | – | – | 75 | 193 | 221 | – | – | – | 122 | 173 | 0 | 61 | 68 | 76 |
| Nuclear Periphery | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 1 | – | – | – | 1 | 1 | 0 | 0 | 0 | 0 |
| Nucleolus | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | 0 | 0 | 0 | 0 | 1 | 1 |
| Peroxisomes | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 | – | – | – | 0 | 0 | 0 | 0 | 0 | 0 |
| SpindlePole | 0 | 0 | – | – | – | – | – | – | – | – | – | – | 0 | 1 | 2 | – | – | – | 7 | 2 | 0 | 3 | 8 | 12 |
| Vac/Vac Membrane | 41 | 63 | – | – | – | – | – | – | – | – | – | – | 11 | 33 | 53 | – | – | – | 54 | 35 | 0 | 42 | 60 | 92 |
| Unique Cell Count | 184 | 210 | 106 | 305 | 375 | 218 | 237 | 1 | 138 | 193 | 274 | |||||||||||||
| Labelled Cell Count | 229 | 242 | 111 | 320 | 403 | 218 | 237 | 1 | 138 | 193 | 274 | |||||||||||||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 3.8 | 5.3 | – | – | – | – | – | – | – | – | – | – | 5.4 | 5.8 | 5.5 | – | – | – | 5.1 | 5.7 | 6.2 |
| Std Deviation (1e-4) | 0.5 | 1.1 | – | – | – | – | – | – | – | – | – | – | 1.1 | 1.6 | 1.3 | – | – | – | 1.2 | 2.2 | 2.0 |
| Intensity Change (Log2) | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | 0.1334 | 0.5604 | 0.4716 | 0.4753 | 0.1696 | 0.5227 | 0.8236 | 0.379 | 0.2639 | -0.0819 | 1.5645 | 0.4601 | -0.0073 | 0.4509 | 0.0906 | 0.4543 | -0.018 | 0.3988 |
| Actin | 0.0006 | 0.0029 | 0.0001 | 0.0001 | 0.0002 | 0.0003 | 0.0177 | 0.0001 | 0.0014 | 0.0001 | 0.0302 | 0.0094 | 0.0057 | 0.0001 | 0.0028 | 0 | 0.0002 | 0.0002 |
| Bud | 0.0009 | 0.0003 | 0.0008 | 0 | 0.0001 | 0.0025 | 0.0005 | 0.0001 | 0.0001 | 0 | 0.0003 | 0.0003 | 0.0002 | 0.0003 | 0 | 0 | 0.0025 | 0 |
| Bud Neck | 0.0003 | 0.0007 | 0.0002 | 0.0001 | 0.0004 | 0.0017 | 0.0056 | 0.0006 | 0.0004 | 0.0003 | 0.0039 | 0.0036 | 0.0043 | 0.001 | 0.0003 | 0.0002 | 0.0007 | 0.0015 |
| Bud Periphery | 0.0004 | 0.0001 | 0.0002 | 0 | 0 | 0.0005 | 0.0007 | 0.0001 | 0.0001 | 0 | 0.0008 | 0.0004 | 0.0005 | 0.0001 | 0 | 0 | 0.0008 | 0 |
| Bud Site | 0.0002 | 0.0012 | 0.0002 | 0 | 0.0001 | 0.0005 | 0.0031 | 0.001 | 0.0004 | 0 | 0.0007 | 0.0008 | 0.0006 | 0.0101 | 0.0001 | 0.0001 | 0.0003 | 0.0001 |
| Cell Periphery | 0 | 0 | 0 | 0 | 0 | 0.0001 | 0.0003 | 0 | 0 | 0 | 0.0002 | 0.0001 | 0.0001 | 0 | 0 | 0 | 0.0002 | 0 |
| Cytoplasm | 0.0224 | 0.0482 | 0.0185 | 0.0101 | 0.0167 | 0.0341 | 0.0385 | 0.0544 | 0.0509 | 0.0176 | 0.0093 | 0.0326 | 0.0288 | 0.0595 | 0.0216 | 0.0255 | 0.0332 | 0.0133 |
| Cytoplasmic Foci | 0.0071 | 0.0016 | 0.0006 | 0.0002 | 0.0018 | 0.0046 | 0.0095 | 0.0009 | 0.0036 | 0.0007 | 0.0056 | 0.003 | 0.002 | 0.0046 | 0.0005 | 0.0002 | 0.0183 | 0.0004 |
| Eisosomes | 0 | 0 | 0 | 0 | 0 | 0 | 0.0002 | 0 | 0 | 0 | 0.0005 | 0.0001 | 0.0001 | 0 | 0 | 0 | 0 | 0 |
| Endoplasmic Reticulum | 0.0011 | 0.0011 | 0.0007 | 0.0001 | 0.0007 | 0.0004 | 0.0069 | 0.0014 | 0.001 | 0.0017 | 0.0086 | 0.0014 | 0.0015 | 0.0013 | 0.0007 | 0.0003 | 0.0005 | 0.0004 |
| Endosome | 0.0025 | 0.0017 | 0.0009 | 0.0002 | 0.0015 | 0.001 | 0.0214 | 0.001 | 0.0021 | 0.0007 | 0.0451 | 0.0079 | 0.0032 | 0.0015 | 0.0018 | 0.0003 | 0.0007 | 0.0013 |
| Golgi | 0.0001 | 0.0001 | 0 | 0 | 0 | 0 | 0.0046 | 0 | 0.0017 | 0 | 0.0158 | 0.0023 | 0.0005 | 0 | 0.0002 | 0 | 0 | 0 |
| Lipid Particles | 0.0009 | 0.0002 | 0.0001 | 0 | 0.0001 | 0.0001 | 0.0059 | 0.0001 | 0.001 | 0.0001 | 0.0763 | 0.0023 | 0.0007 | 0.0001 | 0.0002 | 0 | 0.0005 | 0.0002 |
| Mitochondria | 0.0006 | 0.0003 | 0.0003 | 0.0002 | 0.0003 | 0.0006 | 0.0033 | 0.0005 | 0.0021 | 0.0005 | 0.0154 | 0.001 | 0.0045 | 0.0009 | 0.0003 | 0.0002 | 0.0061 | 0.0002 |
| None | 0.0383 | 0.039 | 0.052 | 0.0799 | 0.083 | 0.05 | 0.0406 | 0.0998 | 0.0906 | 0.0637 | 0.0055 | 0.0273 | 0.026 | 0.0225 | 0.0323 | 0.0366 | 0.0678 | 0.0034 |
| Nuclear Periphery | 0.0177 | 0.0133 | 0.0193 | 0.0071 | 0.0111 | 0.0095 | 0.0526 | 0.0134 | 0.0093 | 0.0264 | 0.1342 | 0.0146 | 0.0104 | 0.0153 | 0.0065 | 0.0046 | 0.0098 | 0.0084 |
| Nucleolus | 0.0062 | 0.0062 | 0.0055 | 0.0054 | 0.007 | 0.011 | 0.0076 | 0.0056 | 0.0039 | 0.005 | 0.0087 | 0.0096 | 0.0054 | 0.0038 | 0.0028 | 0.0035 | 0.0086 | 0.007 |
| Nucleus | 0.8532 | 0.8355 | 0.867 | 0.8606 | 0.8368 | 0.809 | 0.7177 | 0.8019 | 0.7931 | 0.8639 | 0.5715 | 0.8252 | 0.8558 | 0.8563 | 0.9224 | 0.8611 | 0.7792 | 0.9356 |
| Peroxisomes | 0.0002 | 0.0007 | 0 | 0 | 0 | 0.0001 | 0.0163 | 0 | 0.0064 | 0 | 0.0133 | 0.0007 | 0.0006 | 0.0001 | 0.0001 | 0 | 0.0005 | 0.0001 |
| Punctate Nuclear | 0.0458 | 0.0446 | 0.0331 | 0.0356 | 0.0393 | 0.0731 | 0.041 | 0.0177 | 0.0311 | 0.0182 | 0.0445 | 0.0563 | 0.0468 | 0.0208 | 0.0067 | 0.0671 | 0.0685 | 0.0271 |
| Vacuole | 0.0008 | 0.0019 | 0.0004 | 0.0001 | 0.0006 | 0.0007 | 0.0039 | 0.0011 | 0.0006 | 0.0005 | 0.0026 | 0.0008 | 0.0016 | 0.0013 | 0.0004 | 0.0002 | 0.001 | 0.0007 |
| Vacuole Periphery | 0.0006 | 0.0003 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0.002 | 0.0003 | 0.0002 | 0.0004 | 0.0069 | 0.0005 | 0.0005 | 0.0003 | 0.0001 | 0.0001 | 0.0005 | 0.0002 |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 5.8977 | 9.5858 | 6.4018 | 11.1751 | 4.866 | 9.6454 | 7.996 | 10.4665 | 7.8537 | 11.8579 |
| Translational Efficiency | 1.0678 | 0.4587 | 0.9036 | 0.4568 | 1.1211 | 0.7223 | 0.5832 | 0.5339 | 0.7489 | 0.4468 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | ✘ |
| Protein Localization | ✘ |
| Gene Expression | ✘ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 1343 | 334 | 148 | 143 | 1654 | 2116 | 2110 | 820 | 2997 | 2450 | 2258 | 963 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 634.71 | 770.34 | 862.82 | 895.25 | 654.64 | 711.69 | 810.59 | 810.73 | 645.71 | 719.69 | 814.01 | 823.28 |
| Standard Deviation | 65.50 | 89.87 | 118.75 | 106.50 | 75.82 | 84.65 | 98.92 | 106.36 | 72.06 | 87.72 | 101.17 | 110.55 |
| Intensity Change Log 2 | — | 0.279398 | 0.442962 | 0.496193 | — | 0.120547 | 0.308271 | 0.308520 | — | 0.200931 | 0.376147 | 0.403957 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.000086 | 0.002091 | 0.000478 | 0.001081 | 0.000071 | 0.000131 | 0.000269 | 0.001374 | 0.000078 | 0.000398 | 0.000282 | 0.001330 |
| Bud Neck | 0.007263 | 0.011879 | 0.003519 | 0.004804 | 0.003774 | 0.007257 | 0.005992 | 0.006850 | 0.005337 | 0.007887 | 0.005830 | 0.006546 |
| Bud Site | 0.002555 | 0.004435 | 0.001347 | 0.007419 | 0.002944 | 0.002752 | 0.002745 | 0.007156 | 0.002769 | 0.002982 | 0.002653 | 0.007195 |
| Cell Periphery | 0.000154 | 0.000195 | 0.000081 | 0.000161 | 0.000228 | 0.000114 | 0.000090 | 0.000100 | 0.000195 | 0.000125 | 0.000090 | 0.000109 |
| Cytoplasm | 0.249814* | 0.116390* | 0.006432 | 0.044281 | 0.245059* | 0.138615* | 0.047248 | 0.054813 | 0.247190* | 0.135585* | 0.044573 | 0.053249 |
| Cytoplasmic Foci | 0.085668 | 0.042895 | 0.000533 | 0.000498 | 0.029425 | 0.014643 | 0.000935 | 0.004521 | 0.054628 | 0.018494 | 0.000909 | 0.003923 |
| Eisosomes | 0.000072 | 0.000077 | 0.000037 | 0.000056 | 0.000029 | 0.000021 | 0.000013 | 0.000026 | 0.000048 | 0.000028 | 0.000014 | 0.000031 |
| Endoplasmic Reticulum | 0.000956 | 0.004586 | 0.006798 | 0.016843 | 0.000806 | 0.001196 | 0.002645 | 0.004833 | 0.000873 | 0.001658 | 0.002917 | 0.006616 |
| Endosome | 0.002215 | 0.002876 | 0.001251 | 0.000958 | 0.001022 | 0.002008 | 0.000710 | 0.005001 | 0.001556 | 0.002126 | 0.000746 | 0.004401 |
| Golgi | 0.001217 | 0.001857 | 0.000037 | 0.000062 | 0.000239 | 0.001126 | 0.000265 | 0.004574 | 0.000677 | 0.001226 | 0.000250 | 0.003904 |
| Lipid Particles | 0.006088 | 0.004846 | 0.000597 | 0.000797 | 0.002768 | 0.001490 | 0.000219 | 0.000843 | 0.004256 | 0.001948 | 0.000244 | 0.000836 |
| Mitochondria | 0.005853 | 0.004253 | 0.000737 | 0.001017 | 0.001303 | 0.005847 | 0.001216 | 0.005754 | 0.003342 | 0.005630 | 0.001185 | 0.005051 |
| Mitotic Spindle | 0.003533 | 0.006071 | 0.000055 | 0.000727 | 0.002079 | 0.005264 | 0.006703 | 0.016542 | 0.002731 | 0.005374 | 0.006268 | 0.014194 |
| None | 0.008367 | 0.005286 | 0.001457 | 0.004065 | 0.007244 | 0.006054 | 0.004303 | 0.003965 | 0.007747 | 0.005950 | 0.004116 | 0.003980 |
| Nuclear Periphery | 0.001022 | 0.001449 | 0.000748 | 0.001719 | 0.001205 | 0.001325 | 0.001398 | 0.001505 | 0.001123 | 0.001342 | 0.001356 | 0.001537 |
| Nuclear Periphery Foci | 0.000311 | 0.000639 | 0.000148 | 0.000657 | 0.000326 | 0.000526 | 0.000243 | 0.001385 | 0.000319 | 0.000542 | 0.000237 | 0.001277 |
| Nucleolus | 0.003423 | 0.006640 | 0.001710 | 0.000873 | 0.001808 | 0.002200 | 0.000823 | 0.000972 | 0.002532 | 0.002805 | 0.000881 | 0.000957 |
| Nucleus | 0.606817* | 0.764190* | 0.963153* | 0.884400* | 0.692813* | 0.802656* | 0.919443* | 0.860826* | 0.654277* | 0.797412* | 0.922308* | 0.864327* |
| Peroxisomes | 0.005780 | 0.007469 | 0.000178 | 0.000327 | 0.000844 | 0.001617 | 0.000108 | 0.000852 | 0.003056 | 0.002415 | 0.000112 | 0.000774 |
| Vacuole | 0.008372 | 0.011250 | 0.009799 | 0.029120 | 0.005555 | 0.004552 | 0.004139 | 0.016740 | 0.006817 | 0.005465 | 0.004510 | 0.018578 |
| Vacuole Periphery | 0.000433 | 0.000626 | 0.000903 | 0.000135 | 0.000458 | 0.000606 | 0.000495 | 0.001368 | 0.000447 | 0.000609 | 0.000522 | 0.001185 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | -1.27 | -5.71 | -7.68 | 0.22 | -4.49 | -2.68 | -4.23 | -2.48 | -2.35 | -1.90 | -1.49 | -4.78 | -3.06 | -2.00 | -2.34 |
| Bud Neck | -1.50 | 1.08 | -1.59 | 0.87 | -1.96 | -3.27 | -3.30 | -4.71 | -2.20 | -2.47 | -2.65 | -1.83 | -4.17 | -1.84 | -2.72 |
| Bud Site | -1.30 | 1.00 | -1.78 | -1.07 | -2.03 | 0.16 | 0.00 | -2.30 | -2.57 | -2.47 | -0.33 | -0.13 | -2.95 | -2.79 | -2.89 |
| Cell Periphery | -1.18 | 3.84 | -2.03 | -0.18 | -4.25 | 2.43 | 3.04 | 2.55 | 0.31 | -2.16 | 2.54 | 4.07 | 2.69 | 0.11 | -3.65 |
| Cytoplasm | 11.77 | 36.93 | 18.32 | 5.36 | -4.16 | 14.52 | 31.03 | 24.62 | 13.04 | -2.38 | 19.20 | 42.17 | 31.62 | 14.12 | -2.77 |
| Cytoplasmic Foci | 6.88 | 22.16 | 22.14 | 8.62 | -0.69 | 6.65 | 15.66 | 12.93 | 7.80 | -3.20 | 14.87 | 26.15 | 23.67 | 10.87 | -3.18 |
| Eisosomes | -0.49 | 3.74 | -1.31 | -0.47 | -3.66 | 4.64 | 8.92 | -4.89 | -8.18 | -10.81 | 8.21 | 16.86 | -0.38 | -6.85 | -12.28 |
| Endoplasmic Reticulum | -7.58 | -8.21 | -10.71 | -8.37 | -5.90 | -4.07 | -16.11 | -15.34 | -14.60 | -10.19 | -7.52 | -17.84 | -18.00 | -16.34 | -12.40 |
| Endosome | -0.82 | 1.66 | 2.44 | 2.35 | -0.43 | -2.13 | 1.78 | -2.89 | -1.48 | -3.33 | -1.24 | 3.99 | -2.12 | -1.22 | -3.43 |
| Golgi | -0.54 | 2.41 | 2.29 | 1.72 | -3.79 | -2.16 | 0.25 | -1.93 | -1.08 | -1.97 | -1.24 | 1.94 | -1.41 | -0.82 | -1.96 |
| Lipid Particles | 1.29 | 9.97 | 9.13 | 4.62 | -2.27 | 3.59 | 7.97 | 5.35 | 2.94 | -5.52 | 6.69 | 13.50 | 10.41 | 4.95 | -6.29 |
| Mitochondria | 1.10 | 4.40 | 3.82 | 3.20 | -2.45 | -4.24 | 0.07 | -1.60 | 1.16 | -1.63 | -2.17 | 3.71 | -0.03 | 1.43 | -1.67 |
| Mitotic Spindle | -1.25 | 2.50 | -0.80 | 0.02 | -1.48 | -2.38 | -3.12 | -4.32 | -3.37 | -2.80 | -2.32 | -2.64 | -4.24 | -3.24 | -2.86 |
| None | 2.34 | 6.59 | 3.30 | 1.05 | -3.15 | 1.28 | 3.60 | 3.55 | 2.62 | -0.15 | 2.25 | 5.16 | 4.97 | 2.81 | -0.46 |
| Nuclear Periphery | -2.69 | 0.30 | -6.41 | -4.76 | -6.29 | -0.73 | -2.94 | -8.24 | -7.47 | -5.68 | -1.71 | -3.80 | -10.47 | -8.46 | -6.63 |
| Nuclear Periphery Foci | -2.16 | 1.32 | -4.59 | -2.66 | -5.25 | -0.97 | 0.66 | -2.65 | -1.97 | -2.88 | -1.23 | 0.93 | -3.05 | -2.19 | -3.29 |
| Nucleolus | -2.20 | 3.45 | 4.94 | 4.21 | 1.33 | -0.51 | 2.53 | 2.17 | 3.65 | -1.01 | -0.27 | 5.02 | 5.06 | 5.37 | -0.88 |
| Nucleus | -9.09 | -27.98 | -11.04 | -2.66 | 6.26 | -12.28 | -28.57 | -11.30 | -1.93 | 9.63 | -19.16 | -42.04 | -17.25 | -2.71 | 10.86 |
| Peroxisomes | -0.58 | 6.39 | 6.23 | 2.93 | -1.16 | -2.51 | 5.95 | 1.28 | 3.01 | -1.66 | 1.21 | 7.33 | 5.72 | 4.21 | -1.75 |
| Vacuole | -2.84 | -1.88 | -5.30 | -4.94 | -3.94 | 1.24 | -0.84 | -9.73 | -9.96 | -9.60 | 2.04 | -0.27 | -10.86 | -11.12 | -10.74 |
| Vacuole Periphery | -1.38 | -0.47 | 4.63 | 3.64 | 0.91 | -0.57 | 0.20 | -0.84 | -0.51 | -1.03 | -0.94 | 0.12 | -0.81 | -0.27 | -0.82 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p |
| Localization | |
| Cell Percentages | nucleus (43%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | nucleus-3 |
Nej1
Nej1
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Nej1-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
