Standard name
Human Ortholog
Description Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.24 0.23 0.37 0.57 0.23 0.18 0.24 0.25 0.36 0.33 0.54 0.41 0.68 0.84 0.92 0.23 0.19 0.2 0 0 0 0.06 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.49 0.14 0.09 0.07 0.06 0.09 0.06 0 0 0.08 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.1 0.14 0.25 0.1 0.22 0.32 0.41 0.33 0.23 0.25 0.11 0.15 0.09 0 0 0.47 0.41 0.41 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.56 0.73 0.57 0.45 0.72 0.61 0.59 0.68 0.69 0.66 0.62 0.58 0.29 0.2 0.1 0.47 0.54 0.48 0.86 0.84 0.88 0.85 0.86 0.83
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 2 0 0 0 0 1 0 0 0 1 1 0 0 0 0 0 1 0 0 0
Bud 1 0 0 0 0 0 0 2 0 5 1 0 1 0 0 0 0 0 2 2 2 4 3 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 1 1 0 0 3 0 0 0 0 0 0 0 0 0
Cytoplasm 45 25 64 60 40 20 60 88 146 168 115 128 138 245 326 42 40 37 6 2 3 11 12 12
Endoplasmic Reticulum 1 0 1 0 4 1 2 0 3 2 3 1 7 1 1 10 7 11 0 0 1 0 0 1
Endosome 0 0 3 4 1 0 1 0 0 0 0 0 3 2 0 3 9 4 7 7 5 1 8 19
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 0 0 0 1 0 0 2
Mitochondria 90 16 15 7 10 10 14 13 18 39 18 11 0 2 1 3 4 5 2 2 3 3 6 7
Nucleus 18 16 43 11 38 36 102 114 94 130 23 47 19 6 6 86 89 76 1 3 0 2 4 6
Nuclear Periphery 1 0 0 0 3 3 1 1 3 1 0 3 0 0 0 1 1 0 1 0 0 0 2 3
Nucleolus 0 0 0 0 3 0 1 0 2 1 0 2 0 0 0 0 3 0 0 0 0 0 0 2
Peroxisomes 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 0 0 1 0 0 1 1 0 1 1 0 1 1 0 0 1 0 1 0 1 0 2 2
Vac/Vac Membrane 104 81 99 48 125 69 147 239 275 337 132 180 59 59 35 86 116 88 168 106 173 158 275 296
Unique Cell Count 185 111 174 106 174 113 251 350 401 514 214 312 202 291 355 183 215 184 195 127 197 186 321 359
Labelled Cell Count 261 138 225 131 226 139 329 458 541 685 295 373 228 318 375 232 271 221 195 127 197 186 321 359


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 5.7 5.1 5.3 6.8 7.3 7.3 7.0 7.1 7.0 6.6 6.5 5.9 5.7 5.3 7.2 7.2 6.9 6.6 6.6 6.8
Std Deviation (1e-4) 0.8 1.3 1.3 2.3 1.8 2.3 2.5 2.3 2.4 2.2 2.2 2.1 1.1 1.2 1.5 1.5 1.8 1.9 1.7 1.6 1.8
Intensity Change (Log2) – – – 0.07 0.42 0.53 0.52 0.48 0.48 0.47 0.39 0.36 0.23 0.16 0.08 0.5 0.5 0.44 0.38 0.39 0.43


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3.2 -2.8 -3.5 -2.9 -2.8 -0.1 -1.0 3.3 0.9 6.1 10.5 13.5 -2.9 -4.0 -3.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.7 0 2.8
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 1.4 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -0.6 -1.0 0.1 -1.2 -2.4 -2.0 -0.4 -0.1 -2.4 -4.3 -4.4 -5.3 -3.0 -3.1 -2.4
Nucleus -2.9 -0.6 1.3 3.4 1.8 -0.3 0.2 -3.6 -2.6 -4.0 -7.7 -8.6 4.4 3.5 3.3
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -1.9 2.9 0.7 0.3 2.6 2.7 2.1 1.0 0.2 -5.4 -8.1 -11.7 -1.9 -0.6 -1.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.4242 3.2531 2.4866 2.0204 2.1704 2.7246 1.2938 2.3103 1.8234 2.7852 1.9796 2.1776 0.1792 1.7776 1.2295 1.5268 1.7651 1.5309
Actin 0.018 0.0001 0.0083 0 0.0068 0.0034 0.0284 0.0004 0.0007 0.0002 0.0062 0.0007 0.0094 0 0.0005 0 0.005 0.0005
Bud 0.0004 0.0005 0.0006 0.0003 0.0005 0.0008 0.0007 0.0007 0.0009 0.0003 0.0004 0.0005 0.0004 0.0004 0.0003 0.0003 0.0004 0.0003
Bud Neck 0.0013 0.0013 0.0012 0.0009 0.0014 0.002 0.0019 0.0025 0.0018 0.001 0.0018 0.0028 0.0009 0.0011 0.0011 0.0007 0.0008 0.0016
Bud Periphery 0.0008 0.001 0.0014 0.0009 0.0017 0.0026 0.0018 0.0016 0.0015 0.0008 0.0011 0.0016 0.0009 0.0009 0.0009 0.0008 0.0008 0.0009
Bud Site 0.0026 0.0038 0.0022 0.001 0.002 0.0018 0.0044 0.0047 0.0027 0.0008 0.0011 0.001 0.0007 0.0017 0.0016 0.0007 0.0012 0.0008
Cell Periphery 0.0016 0.0036 0.0025 0.001 0.0028 0.0037 0.0019 0.0033 0.0026 0.0016 0.0027 0.0033 0.0015 0.0032 0.0017 0.0017 0.001 0.0029
Cytoplasm 0.0134 0.0182 0.009 0.0032 0.0021 0.0087 0.0209 0.017 0.0096 0.0066 0.0096 0.0047 0.0078 0.009 0.0066 0.0008 0.0046 0.0063
Cytoplasmic Foci 0.0282 0.0071 0.015 0.0075 0.0176 0.0136 0.012 0.0091 0.0121 0.0026 0.0073 0.0069 0.013 0.0091 0.0097 0.002 0.0184 0.0075
Eisosomes 0.0003 0 0.0001 0 0.0001 0.0001 0.0003 0 0 0 0.0002 0 0.0001 0 0.0001 0 0.0001 0
Endoplasmic Reticulum 0.0046 0.0039 0.0025 0.0009 0.0017 0.0032 0.0098 0.0034 0.0025 0.0031 0.0052 0.0022 0.003 0.0019 0.0031 0.0006 0.0008 0.0017
Endosome 0.2032 0.1052 0.1918 0.2331 0.1437 0.1506 0.2293 0.128 0.2123 0.1357 0.1102 0.1347 0.2216 0.1135 0.2049 0.1658 0.1416 0.152
Golgi 0.0141 0.0013 0.0095 0.0065 0.0123 0.0072 0.0169 0.0023 0.0159 0.0031 0.0155 0.004 0.0088 0.0019 0.0057 0.0034 0.0032 0.003
Lipid Particles 0.0404 0.0033 0.0265 0.0055 0.0403 0.0211 0.0164 0.0098 0.0143 0.0058 0.0111 0.0081 0.0191 0.005 0.0114 0.0039 0.0183 0.0166
Mitochondria 0.0148 0.0013 0.0578 0.0117 0.0051 0.0149 0.0365 0.0112 0.0258 0.0482 0.0199 0.0034 0.0117 0.0053 0.0307 0.0022 0.0106 0.0022
None 0.0769 0.0113 0.0279 0.0038 0.0012 0.0051 0.0085 0.0079 0.0076 0.0001 0.0076 0.0053 0.0085 0.0086 0.0034 0.0001 0.0051 0.0005
Nuclear Periphery 0.013 0.0035 0.0042 0.0017 0.0035 0.0102 0.029 0.0056 0.0062 0.0029 0.0204 0.0095 0.0096 0.0105 0.0052 0.0014 0.0105 0.0095
Nucleolus 0.0035 0.0027 0.0068 0.0038 0.0029 0.0041 0.0044 0.0104 0.008 0.0026 0.0025 0.0057 0.0034 0.0068 0.0045 0.0026 0.0025 0.0048
Nucleus 0.0073 0.004 0.0056 0.0052 0.0038 0.0058 0.0139 0.0102 0.0149 0.0311 0.0079 0.0085 0.0052 0.0088 0.0076 0.0028 0.022 0.0124
Peroxisomes 0.0117 0.0002 0.0023 0.0011 0.0258 0.0045 0.0116 0.0007 0.0032 0.0008 0.0016 0.0031 0.003 0.0004 0.0015 0.0004 0.0092 0.0007
Punctate Nuclear 0.0085 0.0001 0.0006 0.0002 0.0045 0.0015 0.0039 0.0003 0.0017 0.0001 0.0009 0.0015 0.0009 0.0002 0.0005 0 0.0271 0.0032
Vacuole 0.4182 0.6895 0.4958 0.5987 0.6199 0.6159 0.4375 0.6624 0.5481 0.6367 0.6732 0.6729 0.5033 0.649 0.5557 0.6459 0.5663 0.6221
Vacuole Periphery 0.117 0.1381 0.1283 0.113 0.1001 0.1193 0.11 0.1084 0.1075 0.116 0.0934 0.1197 0.1672 0.1624 0.1433 0.1638 0.1506 0.1506

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 194.9594 341.2408 172.2517 391.9986 514.0432 153.9163 237.6696 160.1611 316.6733 487.0685
Translational Efficiency 1.257 1.2788 1.0772 1.1089 1.0526 1.2514 1.3001 1.0769 1.0838 1.149

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
93 333 1042 809 1888 2187 527 1002 1981 2520 1569 1811

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 794.40 861.38 860.48 846.09 742.48 783.96 900.90 871.21 744.92 794.19 874.06 859.99
Standard Deviation 111.51 111.05 101.64 121.08 98.73 101.51 113.05 131.46 99.98 106.11 107.32 127.54
Intensity Change Log 2 — 0.116784 0.115276 0.090946 — 0.078428 0.279015 0.230668 — 0.098381 0.196702 0.160138

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000320 0.000076 0.000128 0.000612 0.000024 0.000078 0.000260 0.001085 0.000038 0.000077 0.000172 0.000874
Bud Neck 0.023602 0.021886 0.039160 0.009589 0.018580 0.015405 0.012713 0.011761 0.018816 0.016262 0.030277 0.010791
Bud Site 0.056851 0.018650 0.010871 0.031494 0.006740 0.013761 0.013494 0.058019 0.009092 0.014407 0.011752 0.046170
Cell Periphery 0.000579 0.000419 0.000165 0.000128 0.000786 0.000604 0.000161 0.000188 0.000777 0.000579 0.000164 0.000161
Cytoplasm 0.097244 0.049589 0.129268* 0.382475* 0.036647 0.030540 0.309168* 0.348275* 0.039492 0.033057 0.189693* 0.363552*
Cytoplasmic Foci 0.040989 0.030092 0.027089 0.047293 0.012693 0.013787 0.039830 0.058916 0.014021 0.015942 0.031368 0.053724
Eisosomes 0.000070 0.000034 0.000065 0.000058 0.000030 0.000018 0.000073 0.000073 0.000031 0.000020 0.000068 0.000066
Endoplasmic Reticulum 0.004458 0.000952 0.004867 0.002204 0.003123 0.002282 0.004257 0.002357 0.003186 0.002106 0.004662 0.002289
Endosome 0.074357 0.089459 0.085899 0.019194 0.048367 0.070705 0.042382 0.031538 0.049587 0.073183 0.071282 0.026024
Golgi 0.002576 0.000836 0.000576 0.010134 0.001032 0.002615 0.000267 0.006633 0.001105 0.002380 0.000472 0.008197
Lipid Particles 0.016865 0.001221 0.003628 0.002971 0.001961 0.001186 0.004689 0.002184 0.002661 0.001191 0.003985 0.002536
Mitochondria 0.011201 0.000363 0.001047 0.002727 0.000907 0.005572 0.000398 0.003263 0.001391 0.004884 0.000829 0.003023
Mitotic Spindle 0.001561 0.000193 0.003809 0.043176 0.000380 0.001312 0.003779 0.043293 0.000435 0.001164 0.003799 0.043240
None 0.002858 0.000066 0.002743 0.004250 0.000228 0.000340 0.003108 0.003100 0.000352 0.000304 0.002866 0.003614
Nuclear Periphery 0.002408 0.000152 0.003075 0.001840 0.000240 0.000234 0.002551 0.002211 0.000341 0.000224 0.002899 0.002046
Nuclear Periphery Foci 0.014213 0.000333 0.002902 0.003556 0.000575 0.000114 0.004111 0.003087 0.001215 0.000143 0.003308 0.003297
Nucleolus 0.012628 0.000754 0.010255 0.002270 0.000870 0.001071 0.003220 0.001669 0.001422 0.001029 0.007892 0.001938
Nucleus 0.050958 0.006187 0.256196* 0.093096 0.012582 0.007019 0.238894* 0.074976 0.014383 0.006909 0.250385* 0.083071
Peroxisomes 0.005615 0.002884 0.005332 0.003921 0.000708 0.001315 0.003651 0.007619 0.000938 0.001522 0.004767 0.005967
Vacuole 0.559577* 0.753061* 0.409467* 0.329237* 0.841465* 0.811171* 0.311899* 0.333168* 0.828232* 0.803492* 0.376695* 0.331412*
Vacuole Periphery 0.021069 0.022793 0.003459 0.009775 0.012062 0.020871 0.001094 0.006584 0.012485 0.021125 0.002665 0.008010

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.26 1.59 -1.05 -4.54 -3.73 -2.30 -6.72 -5.39 -4.93 -2.98 -1.82 -8.86 -7.03 -6.43 -4.88
Bud Neck 0.15 -1.54 1.62 4.19 11.70 1.75 1.90 5.64 4.41 2.57 1.42 -5.17 6.64 6.36 11.63
Bud Site 2.47 3.01 2.59 0.49 -2.36 -4.90 -2.28 -6.86 -4.77 -5.07 -3.54 -1.50 -6.61 -4.31 -5.81
Cell Periphery 1.45 4.29 4.91 6.48 3.51 2.34 11.90 12.09 8.17 0.65 2.77 12.08 12.90 9.24 2.73
Cytoplasm 2.37 -2.01 -10.74 -22.88 -16.57 1.71 -21.44 -30.16 -30.96 -2.63 1.81 -23.24 -40.14 -41.71 -15.53
Cytoplasmic Foci 1.16 1.59 1.61 0.49 0.06 -0.61 -8.08 -12.28 -12.05 -2.53 -1.14 -9.02 -12.08 -11.18 -3.03
Eisosomes 2.61 0.40 0.41 -4.70 0.03 5.15 -10.80 -12.24 -19.25 1.93 4.85 -12.20 -13.25 -22.32 0.81
Endoplasmic Reticulum 2.45 -0.35 1.30 -7.69 8.33 3.52 -4.72 3.21 0.90 6.54 4.64 -6.58 3.44 -0.74 10.38
Endosome -1.01 -0.21 4.88 10.21 14.34 -6.04 4.11 10.34 15.44 2.66 -6.65 -2.80 14.10 20.26 13.16
Golgi 2.54 3.04 0.14 -1.22 -1.47 -2.91 2.49 -2.28 -0.30 -3.56 -2.60 2.21 -2.02 -0.36 -3.17
Lipid Particles 2.60 2.17 2.38 -3.66 4.23 1.61 -2.77 -0.24 -3.97 3.20 2.72 -2.09 0.75 -5.53 5.68
Mitochondria 2.54 2.38 2.38 -2.35 0.13 -4.82 2.35 -1.82 3.97 -3.39 -4.01 1.90 0.19 4.15 -2.03
Mitotic Spindle 1.84 -1.89 -6.82 -7.28 -6.03 -1.49 -2.39 -7.31 -7.03 -4.94 -1.28 -3.79 -10.20 -9.89 -8.04
None 2.49 0.31 -0.89 -7.61 -2.07 -1.02 -6.25 -2.79 -2.64 0.31 0.44 -6.12 -5.56 -5.66 -0.91
Nuclear Periphery 1.40 -0.73 -0.36 -13.31 1.78 0.09 -8.59 -5.00 -4.99 2.82 1.33 -14.06 -9.03 -9.96 3.51
Nuclear Periphery Foci 1.91 1.39 1.46 -5.97 0.55 1.45 -6.88 -5.01 -7.15 1.81 2.33 -4.34 -3.93 -9.57 1.19
Nucleolus 2.71 0.49 2.45 -1.52 7.47 -0.20 -3.41 -1.32 -1.07 2.01 1.19 -8.87 -0.54 -1.48 7.85
Nucleus 2.91 -11.34 -4.49 -22.48 12.66 4.08 -22.97 -16.64 -18.19 14.98 5.07 -34.65 -24.93 -28.41 19.95
Peroxisomes 1.27 0.39 1.93 1.72 3.93 -1.77 -3.43 -3.24 -2.70 -0.89 -1.67 -5.62 -3.14 -2.31 1.70
Vacuole -4.60 3.70 3.00 16.99 -1.92 3.90 38.94* 35.25* 32.33* -6.76 3.19 48.38* 42.23 40.45* -5.25
Vacuole Periphery -0.35 4.28 4.35 7.39 0.74 -6.81 13.78 8.56 14.71 -3.09 -7.00 12.56 10.17 17.07 -0.75
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication
Localization
Cell Percentages vacuole (94%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Exg1

Exg1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Exg1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available