Standard name
Human Ortholog
Description Mitochondrial dicarboxylate carrier; integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.07 0 0 0.05 0.06 0.06 – 0.06 0.06 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.06 0 0 0 0 0 0 – 0 0 0 0 0 0 0.09 0.07 0.06 0 0 0 0 0 0
Cytoplasm 0.1 0.08 0.08 0.09 0 0.06 0 0 – 0.05 0.06 0.05 0.1 0.06 0.09 0.59 0.5 0.56 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.07 0.07 0.09 0 0 0 0 0 0
Endosome 0 0 0 0.05 0 0 0 0 – 0 0 0 0.14 0.22 0.14 0.1 0.13 0.08 0 0.08 0.09 0.07 0.06 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0.1 0.09 0.24 0 0 0 0 0 0 0 0 0.06
Mitochondria 0.89 0.74 0.86 0.88 0.9 0.92 0.95 0.93 – 0.94 0.95 0.95 0.53 0.49 0.43 0.12 0.1 0.07 0.82 0.71 0.74 0.67 0.6 0.59
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.07 0 0 0 0 0 – 0 0 0 0.08 0.09 0.06 0 0.06 0.05 0 0 0.06 0 0.05 0.05
SpindlePole 0 0 0.06 0 0 0 0 0 – 0.07 0.05 0 0 0 0 0.08 0.05 0.08 0 0 0 0 0 0
Vac/Vac Membrane 0 0.2 0 0.05 0.07 0.07 0 0.05 – 0.05 0 0 0.25 0.29 0.28 0.05 0.1 0.08 0 0 0 0.07 0.1 0.11
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 0 0 0 0 0 – 1 0 1 1 0 3 4 5 6 0 4 6 3 6 11
Bud 5 1 23 7 10 25 41 42 – 32 27 31 6 2 4 4 4 9 3 1 3 3 4 4
Bud Neck 0 0 1 0 0 0 1 1 – 1 1 1 0 0 0 4 4 1 0 1 1 3 4 7
Bud Site 2 0 2 0 3 14 10 11 – 13 12 8 0 1 0 0 0 0 – – – – – –
Cell Periphery 0 12 4 3 1 2 0 1 – 1 2 4 4 9 10 17 17 14 0 0 0 0 0 0
Cytoplasm 12 15 25 19 18 30 16 29 – 28 27 27 25 19 28 116 117 126 0 2 2 4 3 3
Endoplasmic Reticulum 0 8 0 0 3 0 1 2 – 0 0 1 2 0 6 13 16 20 0 1 1 3 2 3
Endosome 0 8 12 11 19 4 1 1 – 1 0 0 34 72 47 19 30 18 3 16 29 18 14 12
Golgi 0 8 0 1 0 0 0 0 – 0 0 0 24 31 78 5 5 4 2 7 3 5 8 15
Mitochondria 105 138 284 192 383 496 601 702 – 533 466 534 129 162 140 23 23 15 103 153 253 169 141 170
Nucleus 4 1 1 2 2 22 23 23 – 13 8 9 4 3 1 2 1 1 0 3 0 0 2 1
Nuclear Periphery 0 2 1 1 10 5 8 10 – 6 7 6 1 0 0 0 1 0 0 1 4 2 1 1
Nucleolus 1 1 1 0 10 18 17 17 – 4 12 12 1 1 1 0 0 0 0 0 0 0 2 0
Peroxisomes 0 4 22 7 7 6 8 6 – 7 5 0 19 30 19 3 14 12 5 7 21 9 11 14
SpindlePole 1 4 20 5 14 20 28 32 – 38 24 19 8 12 2 15 12 17 2 1 3 5 4 5
Vac/Vac Membrane 0 38 13 10 28 35 22 35 – 26 13 13 60 95 91 10 24 18 1 9 5 16 22 30
Unique Cell Count 118 187 331 217 425 537 633 753 567 488 560 243 332 328 198 234 224 127 215 345 254 235 287
Labelled Cell Count 130 241 409 258 508 677 777 912 704 604 666 318 437 430 235 273 261 127 215 345 254 235 287


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.3 5.3 4.0 4.5 4.4 3.8 3.3 3.3 – 3.1 3.3 3.2 6.5 7.6 7.4 5.4 5.7 5.6 6.4 6.7 6.5
Std Deviation (1e-4) 1.4 0.9 0.7 2.0 1.4 1.0 0.9 0.8 – 0.7 1.2 0.8 1.3 9.7 1.6 1.1 1.3 1.3 1.9 1.9 1.4
Intensity Change (Log2) – – – 0.17 0.15 -0.06 -0.26 -0.27 – -0.37 -0.3 -0.33 0.71 0.92 0.87 0.43 0.5 0.49 0.68 0.73 0.7


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 – 0 0 0 -2.4 -4.3 -3.7 -2.5 -2.9 -1.5
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 1.4 1.6 4.2 3.7 3.3
Cytoplasm 0.5 -2.0 -1.2 -3.7 -2.6 – -1.6 -1.2 -1.7 1.1 -0.9 0.5 12.8 11.5 12.6
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 4.8 5.5
Endosome 0 0 0 0 0 – 0 0 0 4.5 7.0 4.8 2.8 4.1 2.3
Golgi 0 0 0 0 0 – 0 0 0 5.8 5.7 9.4 0 0 0
Mitochondria 0 0 0 0 0 – 0 0 0 -8.6 -10.2 -11.6 -16.7 -17.9 -18.3
Nucleus 0 0 3.4 3.2 2.8 – 2.3 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0.5 1.1 -0.5 -2.7 -0.3 -0.6
SpindlePole 0 0 0 0 0 – 0 0 0 -1.5 -1.5 -3.9 0.7 -0.5 0.7
Vacuole 0.4 1.6 1.6 -0.4 0.5 – 0.5 -1.0 -1.4 7.4 8.6 8.4 0.6 3.0 2.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.4094 7.4656 6.9784 6.3769 7.1467 7.3827 9.3322 10.1533 9.9125 8.7227 9.1655 10.251 7.4227 7.4299 7.6427 6.638 6.802 7.5005
Actin 0.0111 0.0186 0.0054 0.0015 0.0028 0.0035 0.0111 0.0039 0.0053 0.009 0.004 0.0036 0.0052 0.0192 0.0047 0.002 0.0031 0.0018
Bud 0.0017 0.0034 0.0012 0.0025 0.0037 0.0002 0.0004 0.0003 0.001 0.0004 0.0009 0.0003 0.0004 0.0009 0.0003 0.0005 0.0021 0.0001
Bud Neck 0.0014 0.001 0.0005 0.0002 0.0003 0.0014 0.0005 0.0003 0.0001 0.0001 0.0003 0.0002 0.0003 0.0007 0.0002 0.0003 0.0001 0.0001
Bud Periphery 0.0028 0.0063 0.0024 0.0057 0.0064 0.0005 0.001 0.0006 0.0025 0.0007 0.001 0.0018 0.001 0.0012 0.0009 0.0012 0.0089 0.0002
Bud Site 0.0074 0.0111 0.0034 0.0022 0.0011 0.0003 0.0021 0.0028 0.0015 0.0005 0.0014 0.0003 0.0007 0.0066 0.0006 0.0013 0.0009 0.0001
Cell Periphery 0.0007 0.0016 0.0012 0.0009 0.0005 0.0002 0.0006 0.0017 0.0004 0.0002 0.0002 0.0003 0.0005 0.0006 0.0004 0.0003 0.0005 0.0002
Cytoplasm 0.0005 0.0021 0.0005 0.0002 0.0006 0.0002 0.0015 0.0003 0.0004 0.0001 0.0006 0.0001 0.0003 0.0005 0.0001 0.0001 0.0001 0.0001
Cytoplasmic Foci 0.0116 0.0127 0.0074 0.0023 0.0042 0.0038 0.0091 0.0107 0.005 0.0016 0.0086 0.0029 0.0066 0.0075 0.0039 0.0028 0.002 0.0019
Eisosomes 0.0004 0.0003 0.0003 0.0002 0.0001 0.0001 0.0005 0.0018 0.0003 0.0002 0.0001 0.0002 0.0002 0.0003 0.0003 0.0001 0.0017 0.0013
Endoplasmic Reticulum 0.0005 0.0012 0.0004 0.0006 0.0004 0.0003 0.0009 0.0002 0.0002 0.0001 0.0002 0.0003 0.0029 0.0022 0.0002 0.0001 0.0001 0.0002
Endosome 0.0614 0.0539 0.0247 0.0176 0.038 0.019 0.0212 0.0291 0.0111 0.0105 0.0305 0.0112 0.0266 0.0336 0.011 0.0187 0.0156 0.0143
Golgi 0.0569 0.0724 0.0334 0.0307 0.043 0.0387 0.0363 0.0578 0.014 0.0097 0.0351 0.0296 0.0413 0.0644 0.0331 0.0281 0.0202 0.0416
Lipid Particles 0.0225 0.0116 0.0046 0.0052 0.0015 0.0059 0.0172 0.0071 0.0012 0.0037 0.003 0.0047 0.0218 0.0096 0.005 0.0032 0.0012 0.002
Mitochondria 0.7872 0.7422 0.8879 0.9072 0.8516 0.907 0.8732 0.8697 0.942 0.9517 0.9024 0.9339 0.8581 0.8197 0.9243 0.935 0.931 0.9275
None 0.0003 0.0004 0.0001 0.0002 0.0001 0 0.0008 0.0001 0.0005 0 0.0001 0.0001 0.0002 0.0001 0.0001 0 0.0001 0
Nuclear Periphery 0.0008 0.0005 0.0001 0.0026 0.0004 0.0003 0.0009 0.0002 0.0002 0 0.0001 0.0007 0.0009 0.0037 0.0002 0 0.0001 0.0002
Nucleolus 0.0022 0.0085 0.0009 0.0007 0.0002 0.0001 0.0004 0.0002 0.0001 0.0002 0.0001 0.0001 0.004 0.0047 0.0002 0.0001 0.0001 0.0001
Nucleus 0.0007 0.0015 0.0004 0.0005 0.0003 0.0001 0.0003 0.0002 0.0001 0.0001 0.0001 0.0001 0.0003 0.0012 0.0001 0.0001 0.0002 0.0001
Peroxisomes 0.0054 0.0046 0.0062 0.0038 0.0041 0.0033 0.0131 0.0072 0.0089 0.0031 0.0051 0.0037 0.0082 0.005 0.0042 0.0033 0.0048 0.002
Punctate Nuclear 0.0003 0.0002 0.0001 0.0001 0 0 0.0003 0 0.0001 0 0.0001 0 0.0001 0.0001 0 0 0 0
Vacuole 0.0105 0.0278 0.0114 0.0096 0.0227 0.0028 0.0038 0.0022 0.0026 0.0019 0.0036 0.0016 0.0087 0.0079 0.0044 0.0011 0.0038 0.0017
Vacuole Periphery 0.0137 0.0182 0.0074 0.0055 0.0182 0.0122 0.0048 0.0037 0.0025 0.0061 0.0024 0.0044 0.0117 0.0103 0.0059 0.0016 0.0035 0.0046

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 36.2881 34.0888 30.1912 26.4129 39.8721 36.8827 60.5955 52.5294 48.5724 43.2284
Translational Efficiency 1.2283 1.3261 0.7782 1.0299 0.8768 1.2118 0.9525 0.8697 0.7616 0.8319

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1845 1815 151 211 1759 1474 169 1866 3604 3289 320 2077

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 735.84 780.08 917.30 951.68 764.02 800.28 1006.99 978.50 749.59 789.13 964.67 975.78
Standard Deviation 97.33 128.19 105.66 126.75 115.42 137.51 124.89 138.95 107.47 132.83 124.54 137.99
Intensity Change Log 2 — 0.084230 0.318002 0.371084 — 0.066894 0.398367 0.356961 — 0.075425 0.359498 0.363908

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000570 0.002164 0.006452 0.017345 0.001603 0.004325 0.017840 0.013375 0.001074 0.003132 0.012466 0.013778
Bud Neck 0.015301 0.010638 0.015596 0.022814 0.010094 0.003873 0.026331 0.011929 0.012760 0.007606 0.021265 0.013035
Bud Site 0.026292 0.028956 0.041541 0.159421* 0.021429 0.018778 0.123164* 0.146574* 0.023918 0.024395 0.084648 0.147879*
Cell Periphery 0.001084 0.000550 0.000321 0.000290 0.000781 0.000654 0.000385 0.000504 0.000936 0.000597 0.000355 0.000482
Cytoplasm 0.025465 0.010183 0.110974* 0.071696 0.013754 0.006797 0.031963 0.078912 0.019749 0.008666 0.069247 0.078179
Cytoplasmic Foci 0.084136 0.058118 0.162969 0.157689 0.056631 0.037970 0.138211 0.096882 0.070711 0.049089 0.149894 0.103059
Eisosomes 0.000170 0.000128 0.000223 0.000142 0.000147 0.000129 0.000159 0.000153 0.000159 0.000129 0.000189 0.000152
Endoplasmic Reticulum 0.001327 0.000963 0.009445 0.002785 0.001663 0.000556 0.003659 0.001032 0.001491 0.000781 0.006389 0.001210
Endosome 0.089451 0.093773 0.088954 0.090859 0.077730 0.087140 0.093608 0.063123 0.083730 0.090801 0.091412 0.065941
Golgi 0.086777 0.127952* 0.022422 0.043624 0.103121 0.127604* 0.066522 0.106548 0.094754 0.127796* 0.045712 0.100156
Lipid Particles 0.011272 0.003437 0.019034 0.004502 0.004521 0.002164 0.003565 0.000748 0.007977 0.002866 0.010865 0.001129
Mitochondria 0.548773* 0.567331* 0.038376 0.061071 0.621475* 0.635895* 0.122188* 0.284709* 0.584257* 0.598058* 0.082639 0.261990*
Mitotic Spindle 0.009084 0.013318 0.029832 0.068472 0.007083 0.010215 0.134139* 0.056975 0.008107 0.011928 0.084919 0.058143
None 0.000928 0.000940 0.002159 0.000600 0.000458 0.000217 0.000212 0.000414 0.000699 0.000616 0.001131 0.000433
Nuclear Periphery 0.000454 0.000139 0.003009 0.000360 0.000129 0.000091 0.000678 0.000124 0.000296 0.000118 0.001778 0.000148
Nuclear Periphery Foci 0.000367 0.000281 0.005417 0.001284 0.000158 0.000176 0.001417 0.000202 0.000265 0.000233 0.003304 0.000312
Nucleolus 0.001504 0.000849 0.013463 0.000927 0.000481 0.000208 0.001769 0.000164 0.001005 0.000562 0.007287 0.000241
Nucleus 0.003541 0.002023 0.174830* 0.014566 0.001424 0.000551 0.024091 0.002888 0.002508 0.001363 0.095221 0.004074
Peroxisomes 0.020985 0.033889 0.051761 0.118263* 0.022749 0.022907 0.094942 0.069088 0.021846 0.028967 0.074566 0.074084
Vacuole 0.037206 0.024172 0.182932 0.152274 0.024350 0.019801 0.101141 0.052023 0.030931 0.022213 0.139736 0.062207
Vacuole Periphery 0.035314 0.020196 0.020292 0.011013 0.030216 0.019950 0.014016 0.013635 0.032826 0.020086 0.016977 0.013368

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.07 -3.49 -3.86 -3.45 -2.21 -2.76 -3.32 -8.98 -5.81 0.73 -4.13 -4.25 -10.38 -8.18 -0.60
Bud Neck 2.67 0.21 -1.91 -3.26 -1.87 4.96 -3.25 -1.52 -9.58 2.90 4.66 -2.81 -0.34 -5.65 2.72
Bud Site -0.90 -1.84 -8.76 -8.57 -7.04 1.11 -8.16 -25.36 -25.72* -2.05 -0.25 -7.66 -26.64 -26.46 -7.43
Cell Periphery 1.46 2.06 2.19 3.85 0.88 1.21 4.26 3.23 2.04 -1.94 1.75 3.04 2.40 2.42 -2.61
Cytoplasm 7.34 -6.39 -5.62 -7.35 2.11 4.22 -4.98 -18.33 -21.01 -8.18 8.26 -7.34 -17.96 -21.95 -1.27
Cytoplasmic Foci 7.09 -5.88 -5.40 -7.75 0.96 6.42 -7.08 -10.49 -17.30 3.49 9.04 -8.98 -8.89 -16.21 5.26
Eisosomes 2.22 -2.54 1.25 -1.18 4.30 0.92 -0.51 -0.30 -1.84 0.37 2.24 -2.03 0.56 -2.66 3.13
Endoplasmic Reticulum 1.19 -7.45 -2.98 -3.34 5.14 2.79 -2.41 1.47 -4.32 3.39 2.80 -7.08 0.88 -2.72 7.56
Endosome -0.96 0.47 0.91 1.42 0.23 -2.07 -1.46 4.19 6.26 3.25 -2.21 -0.63 6.45 8.52 3.50
Golgi -7.94 12.40 7.52 13.06 -2.43 -4.12 3.82 -0.09 4.11 -3.89 -8.44 8.26 -0.51 6.89 -8.13
Lipid Particles 6.10 -3.09 3.93 -1.18 5.59 3.00 0.54 5.38 3.37 4.01 6.67 -2.28 9.48 4.95 7.91
Mitochondria -1.66 45.19* 37.15* 38.16* -1.30 -1.25 26.43 31.73* 31.89* -8.65 -1.70 43.46* 37.16* 37.99* -14.45
Mitotic Spindle -2.64 -2.48 -5.84 -5.41 -3.10 -2.20 -7.62 -16.67 -15.08 4.59 -3.54 -7.63 -17.51 -15.95 2.57
None -0.05 -1.89 0.87 0.97 2.41 4.38 2.31 0.25 -1.64 -1.05 0.42 -1.43 1.44 1.06 2.41
Nuclear Periphery 1.69 -4.49 0.04 -3.43 4.70 0.98 -1.86 -0.21 -1.67 1.84 1.82 -4.60 1.30 -1.61 5.19
Nuclear Periphery Foci 0.71 -6.01 -4.06 -4.33 4.70 -0.45 -3.78 -1.80 -1.17 3.58 0.45 -6.82 -1.66 -2.00 6.62
Nucleolus 1.17 -3.99 1.06 -0.12 4.22 1.63 -2.32 2.06 0.38 2.83 1.47 -4.33 3.17 2.19 4.93
Nucleus 2.03 -8.84 -3.25 -3.52 7.55 2.17 -3.08 -3.88 -5.79 2.83 2.59 -8.60 -3.92 -5.31 8.30
Peroxisomes -4.72 -3.68 -6.87 -5.76 -3.94 -0.03 -5.59 -12.15 -11.41 1.89 -3.58 -6.61 -14.69 -11.94 -0.01
Vacuole 5.52 -9.48 -9.03 -9.79 0.12 2.39 -7.00 -10.76 -12.23 4.06 5.68 -11.42 -12.05 -14.73 7.11
Vacuole Periphery 7.66 3.44 10.44 4.83 1.72 5.20 5.88 9.08 4.25 -0.07 9.12 6.18 13.68 5.75 0.96
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial dicarboxylate carrier; integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix
Localization
Cell Percentages mitochondrion (92%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Dic1

Dic1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dic1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available