Standard name
Human Ortholog
Description Scaffold protein responsible for phagophore assembly site organization; regulatory subunit of an autophagy-specific complex that includes Atg1p and Atg13p; stimulates Atg1p kinase activity; human ortholog RB1CC1/FIP200 interacts with p53, which inhibits autophagy in human cells
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0.08 0.07 0 0.09 0.08 0.08 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.92 0.96 0.97 0.85 0.79 0.66 0.59 0.56 0.51 0.49 0.38 0.41 0.96 0.97 0.93 0.92 0.95 0.93 0.77 0.87 0.67 0.88 0.77 0.81
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.09 0 0 0 0 0 0
Endosome 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.11 0 0 0.07 0.08 0.45 0.44 0.41 0.56 0.56 0.74 0.65 0 0 0 0 0 0 0.1 0 0.17 0 0 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.08 0.09 0.06 0.1 0.14 0.12 0.12 0.08 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 2 0 0 0 0 0 1 1 1 0 0 0 4 2 5 0 2 2
Bud 1 2 2 4 16 22 16 26 24 22 21 14 1 0 0 3 0 1 1 1 1 2 7 8
Bud Neck 1 1 0 0 4 4 5 2 3 6 1 1 7 10 10 1 1 2 2 0 1 1 2 1
Bud Site 0 0 0 0 0 0 2 2 0 4 6 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 2 0 1 1 0 1 1 0 1 3 1 1 4 13 10 6 2 0 1 1 0 2
Cytoplasm 336 231 266 107 154 203 215 161 154 132 105 130 392 518 458 349 249 305 279 209 186 273 210 299
Endoplasmic Reticulum 1 3 1 0 0 0 0 0 0 1 0 1 3 2 5 16 18 28 2 1 3 0 1 2
Endosome 0 0 2 4 10 4 7 9 8 4 3 7 3 1 5 13 2 6 9 4 14 6 10 7
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 3 0 0 2 0 0 0
Mitochondria 41 8 2 9 16 139 161 118 168 150 204 206 0 0 2 3 6 9 36 9 47 11 6 19
Nucleus 0 0 0 3 1 0 2 1 1 0 1 1 0 2 0 2 0 0 0 0 0 1 4 0
Nuclear Periphery 1 0 0 2 0 0 0 0 0 3 0 2 0 0 0 0 0 1 0 0 0 0 2 0
Nucleolus 0 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 1
Peroxisomes 0 0 1 3 6 3 3 7 3 7 6 12 0 0 1 1 0 1 0 0 0 0 0 0
SpindlePole 4 1 4 10 17 19 37 39 36 33 21 28 7 12 20 3 2 6 8 2 7 4 6 13
Vac/Vac Membrane 0 0 1 0 1 2 3 0 2 1 6 4 1 2 2 8 6 7 5 2 1 3 8 4
Unique Cell Count 364 240 275 126 194 308 366 287 302 270 276 316 407 535 495 378 262 329 363 242 280 312 274 370
Labelled Cell Count 386 246 281 142 227 397 453 367 400 363 375 414 416 549 508 414 296 375 363 242 280 312 274 370


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.0 3.8 3.9 3.7 3.8 3.0 3.1 3.3 3.0 3.0 2.8 2.7 5.3 5.4 5.5 6.2 5.6 5.5 5.5 6.1 6.1
Std Deviation (1e-4) 0.4 0.6 1.4 1.7 1.8 1.1 1.4 1.8 1.0 1.2 0.9 0.7 1.0 1.2 1.4 1.8 1.6 1.8 1.0 1.8 1.7
Intensity Change (Log2) – – – -0.07 -0.06 -0.37 -0.32 -0.26 -0.38 -0.4 -0.51 -0.52 0.44 0.46 0.48 0.65 0.51 0.49 0.5 0.63 0.63


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.6084 0.1232 -0.1818 -0.431 -0.3608 -0.0126 0.8304 0.2855 0.1235 0.254 0.2508 0.0362 -0.8129 -0.722 -0.6844 -0.5577 -1.2324 -0.7332
Actin 0.0006 0.0006 0.0002 0.0022 0.0004 0.0006 0.0433 0.0028 0.0041 0.0596 0.0038 0.0018 0.024 0.0016 0.0012 0.0003 0.0014 0.0001
Bud 0.0003 0.0007 0.0002 0.0001 0.0015 0.0002 0.0022 0.0018 0.001 0.0007 0.0004 0.0016 0.0006 0.0066 0.0002 0.0094 0.0077 0
Bud Neck 0.0002 0.0003 0 0.0001 0.0004 0.0003 0.0043 0.0002 0.0012 0.0155 0.0015 0.0011 0.0022 0.0001 0.0004 0.0002 0.0004 0.0001
Bud Periphery 0.0004 0.0007 0.0004 0.0002 0.0025 0.0003 0.0049 0.0023 0.0051 0.0014 0.0003 0.0044 0.0006 0.0047 0.0001 0.0025 0.0064 0
Bud Site 0.0014 0.01 0.0007 0 0.0007 0.0001 0.0114 0.0039 0.0006 0.0018 0.0047 0.0007 0.0032 0.0027 0.0022 0.0016 0.0014 0
Cell Periphery 0.0001 0.0002 0.0001 0.0001 0.0001 0 0.0009 0.0002 0.0001 0.0002 0.0001 0.0001 0.0005 0.0002 0.0002 0.0003 0.0002 0
Cytoplasm 0.022 0.0238 0.0407 0.0404 0.0364 0.0395 0.0395 0.0676 0.0852 0.0518 0.0585 0.0833 0.0268 0.0674 0.0419 0.0423 0.036 0.0811
Cytoplasmic Foci 0.0168 0.015 0.0187 0.0443 0.0303 0.0172 0.0609 0.0051 0.012 0.033 0.0454 0.0167 0.0095 0.0072 0.0045 0.0521 0.0137 0.0193
Eisosomes 0.0003 0.0004 0.0002 0.0004 0.0001 0.0001 0.0005 0.0001 0.0001 0.0003 0.0001 0.0001 0.0005 0.0001 0.0003 0.0004 0.0001 0.0001
Endoplasmic Reticulum 0.0007 0.0004 0.0004 0.0005 0.0002 0.0002 0.0036 0.0003 0.0029 0.0021 0.0013 0.0006 0.002 0.0004 0.0016 0.0007 0.0012 0.0005
Endosome 0.0044 0.0017 0.0053 0.0042 0.0067 0.0029 0.0544 0.0007 0.02 0.0378 0.0598 0.0131 0.0107 0.0031 0.001 0.0065 0.0003 0.0085
Golgi 0.0004 0.0003 0.0002 0.0003 0.0013 0.0001 0.0195 0.0006 0.0126 0.0115 0.0169 0.0039 0.0034 0.0001 0.0001 0.0006 0.0002 0.0003
Lipid Particles 0.0016 0.0006 0.0005 0.0027 0.0004 0.0003 0.0387 0.002 0.0041 0.0284 0.0228 0.0026 0.0045 0.0003 0.0007 0.0035 0.0008 0.0004
Mitochondria 0.0003 0.0003 0.0003 0.0006 0.0197 0.0003 0.0127 0.0007 0.0056 0.0352 0.0026 0.0042 0.0016 0.0006 0.0004 0.001 0.0015 0.0002
None 0.9413 0.9406 0.9294 0.8972 0.8911 0.9355 0.6214 0.9032 0.8347 0.693 0.7625 0.8478 0.8788 0.9026 0.9328 0.8551 0.9057 0.8867
Nuclear Periphery 0.0044 0.0002 0.0003 0.0008 0.0001 0.0001 0.0063 0.0003 0.0024 0.0054 0.0014 0.0005 0.0114 0.0002 0.004 0.0009 0.0017 0.0002
Nucleolus 0.0002 0.0006 0.0001 0.0002 0.0003 0.0001 0.0018 0.0004 0.0003 0.0003 0.0004 0.0002 0.0011 0.0003 0.0004 0.0015 0.0013 0.0001
Nucleus 0.0011 0.0008 0.0005 0.0005 0.0003 0.0003 0.0023 0.001 0.0009 0.0005 0.001 0.0008 0.0077 0.0006 0.0056 0.0029 0.003 0.0003
Peroxisomes 0.0012 0.0007 0.0003 0.0022 0.0054 0.0005 0.0538 0.0034 0.0028 0.0151 0.01 0.0065 0.0015 0.0001 0.0001 0.0019 0.0007 0.0003
Punctate Nuclear 0.0019 0.0016 0.0007 0.0019 0.0012 0.0008 0.0102 0.0028 0.0009 0.0041 0.0041 0.0015 0.0075 0.0004 0.0016 0.015 0.0151 0.001
Vacuole 0.0003 0.0005 0.0006 0.0009 0.0006 0.0002 0.0055 0.0004 0.0023 0.0011 0.0019 0.0066 0.0012 0.0008 0.0007 0.0011 0.0009 0.0005
Vacuole Periphery 0.0001 0 0.0001 0.0002 0.0001 0.0001 0.0019 0.0001 0.001 0.001 0.0006 0.002 0.0007 0.0001 0.0002 0.0003 0.0003 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2.6397 2.3598 4.6694 3.1226 3.4225 5.2765 4.1754 4.5627 3.0822 5.8008
Translational Efficiency 1.1822 1.5508 0.5308 0.8339 1.3009 1.0048 0.8527 0.6188 1.1843 0.632

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1236 236 2327 1029 1724 1599 229 678 2960 1835 2556 1707

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 618.26 755.28 769.67 783.63 633.94 686.41 869.58 779.44 627.39 695.27 778.62 781.97
Standard Deviation 65.84 95.26 87.63 100.38 72.51 81.82 93.81 112.33 70.23 86.79 92.70 105.31
Intensity Change Log 2 — 0.288798 0.316026 0.341959 — 0.114724 0.455972 0.298092 — 0.203296 0.388571 0.319917

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000148 0.000867 0.000171 0.000915 0.000057 0.000485 0.000265 0.000628 0.000095 0.000534 0.000180 0.000801
Bud Neck 0.017898 0.033066 0.013134 0.007437 0.011931 0.038097 0.002585 0.006883 0.014423 0.037450 0.012189 0.007217
Bud Site 0.003566 0.014711 0.016724 0.031631 0.002836 0.017569 0.002540 0.015318 0.003141 0.017201 0.015453 0.025152
Cell Periphery 0.000147 0.000230 0.000135 0.000220 0.000114 0.000132 0.000224 0.000174 0.000128 0.000144 0.000143 0.000202
Cytoplasm 0.399082* 0.308792* 0.507175* 0.435305* 0.544330* 0.401178* 0.290277* 0.478150* 0.483679* 0.389296* 0.487743* 0.452323*
Cytoplasmic Foci 0.310526* 0.333369* 0.029812 0.043346 0.194349* 0.269368* 0.054848 0.062546 0.242861* 0.277599* 0.032055 0.050972
Eisosomes 0.000281 0.000158 0.000033 0.000080 0.000096 0.000163 0.000134 0.000080 0.000173 0.000162 0.000042 0.000080
Endoplasmic Reticulum 0.001345 0.000754 0.001031 0.003773 0.000773 0.000552 0.003362 0.002220 0.001012 0.000578 0.001240 0.003156
Endosome 0.019299 0.038273 0.006265 0.011190 0.006950 0.028853 0.011087 0.010102 0.012107 0.030064 0.006697 0.010758
Golgi 0.003939 0.005273 0.000155 0.003509 0.001423 0.005412 0.000138 0.001880 0.002474 0.005394 0.000153 0.002862
Lipid Particles 0.019449 0.006809 0.001394 0.003057 0.005888 0.006524 0.005427 0.003112 0.011550 0.006560 0.001755 0.003079
Mitochondria 0.009409 0.013357 0.001501 0.002407 0.002623 0.012468 0.000377 0.002928 0.005456 0.012582 0.001401 0.002614
Mitotic Spindle 0.000374 0.012805 0.016344 0.025828 0.001062 0.009626 0.000480 0.022553 0.000775 0.010035 0.014923 0.024527
None 0.001967 0.001174 0.005241 0.004502 0.004784 0.001597 0.005257 0.003631 0.003608 0.001543 0.005243 0.004156
Nuclear Periphery 0.000651 0.000593 0.002101 0.002005 0.000375 0.000417 0.001885 0.001149 0.000490 0.000439 0.002082 0.001665
Nuclear Periphery Foci 0.000268 0.000737 0.000668 0.002670 0.000276 0.000268 0.003950 0.003444 0.000272 0.000329 0.000962 0.002977
Nucleolus 0.001086 0.001949 0.001581 0.001373 0.001276 0.001380 0.001450 0.001033 0.001197 0.001453 0.001569 0.001238
Nucleus 0.146311* 0.099501 0.340902* 0.225058* 0.190421* 0.110788 0.478564* 0.193235* 0.172002* 0.109336 0.353235* 0.212419*
Peroxisomes 0.012317 0.034702 0.002362 0.006095 0.003502 0.019354 0.003124 0.002025 0.007183 0.021328 0.002430 0.004478
Vacuole 0.050638 0.089858 0.052835 0.185903 0.026300 0.073746 0.133809 0.187045 0.036463 0.075818 0.060090 0.186356
Vacuole Periphery 0.001298 0.003024 0.000434 0.003695 0.000634 0.002024 0.000220 0.001865 0.000912 0.002152 0.000415 0.002968

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.49 -1.16 -4.06 0.61 -3.76 -6.12 -7.40 -3.39 -0.10 -0.76 -6.15 -4.65 -5.46 -0.54 -4.21
Bud Neck -3.02 1.43 6.49 5.39 5.52 -10.06 4.78 2.82 11.50 -1.31 -9.93 0.00 6.36 13.26 5.53
Bud Site -4.65 -6.44 -6.02 -0.89 -1.23 -8.38 -2.98 -5.09 2.47 -2.79 -9.10 -7.04 -7.76 0.95 -0.86
Cell Periphery -0.86 2.07 -1.04 0.66 -2.42 -1.85 -4.69 -1.25 0.10 3.55 -1.05 0.16 -2.10 -0.47 -1.60
Cytoplasm 5.13 -5.28 5.10 -1.87 10.31 15.26 19.85 14.13 2.55 -7.53 11.57 7.03 15.87 3.92 8.74
Cytoplasmic Foci -1.09 40.49 39.80 19.13 -0.22 -9.79 15.43 23.68 31.35 0.66 -4.86 46.63 44.75 40.35 -2.03
Eisosomes 4.15 10.07 7.97 3.99 -13.11 -7.13 -4.45 2.15 7.95 5.16 0.95 11.76 8.13 9.02 -10.88
Endoplasmic Reticulum 1.53 -0.85 -8.46 -14.38 -12.02 1.44 -9.36 -9.98 -12.72 4.08 2.52 -5.28 -13.41 -19.51 -11.63
Endosome -3.95 7.28 6.34 6.52 -0.99 -12.43 -3.45 -1.48 9.69 2.33 -10.41 4.29 3.50 12.59 -0.67
Golgi -0.65 8.29 3.13 2.13 -1.55 -7.54 7.50 1.16 6.42 -1.21 -5.41 10.87 2.65 6.25 -1.96
Lipid Particles 7.39 11.82 10.73 4.36 -8.40 -1.00 0.44 5.49 6.62 3.72 6.60 13.86 11.97 8.41 -6.27
Mitochondria -0.77 5.84 5.97 2.90 0.82 -6.71 6.28 1.73 7.11 -1.49 -4.76 6.59 6.25 8.22 0.23
Mitotic Spindle -2.30 -8.49 -6.67 -1.58 -1.30 -4.73 -0.64 -4.46 -1.90 -4.35 -5.45 -8.19 -7.92 -3.32 -1.58
None 1.88 -5.01 -2.44 -3.82 1.78 6.64 1.19 2.99 -4.72 1.18 6.24 -2.16 0.48 -4.81 2.42
Nuclear Periphery 0.21 -10.37 -14.30 -12.79 -0.78 -1.04 -12.23 -12.35 -11.94 3.61 0.56 -12.56 -19.04 -19.81 1.44
Nuclear Periphery Foci -3.22 -5.22 -7.71 -6.15 -5.33 0.07 -4.09 -9.38 -9.39 2.01 -1.86 -6.48 -11.46 -11.22 -5.36
Nucleolus -2.54 -4.91 -0.55 1.71 3.91 -0.49 -1.37 0.46 0.92 1.66 -1.45 -4.70 -0.05 1.10 4.39
Nucleus 4.37 -29.12 -10.96 -11.62 14.24 13.00 -11.60 -0.54 -9.25 10.77 12.34 -30.37 -7.90 -17.00 19.50
Peroxisomes -3.54 7.68 6.08 5.13 -0.99 -10.71 -0.91 2.69 11.83 2.30 -8.97 6.79 5.71 11.98 -0.31
Vacuole -5.39 -6.76 -28.41 -16.41 -25.43 -16.17 -12.54 -25.32 -20.56 -4.74 -14.18 -16.31 -38.98 -31.17 -29.47
Vacuole Periphery -2.44 7.59 -0.09 1.68 -1.53 -6.42 8.42 -0.38 2.55 -1.38 -5.86 7.12 -0.52 2.11 -1.83
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Scaffold protein responsible for phagophore assembly site organization; regulatory subunit of an autophagy-specific complex that includes Atg1p and Atg13p; stimulates Atg1p kinase activity; human ortholog RB1CC1/FIP200 interacts with p53, which inhibits autophagy in human cells
Localization
Cell Percentages cytoplasm (31%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Atg17

Atg17


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Atg17-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available