Standard name
Human Ortholog
Description Serine esterase; homolog of human neuropathy target esterase (NTE); Nte1p-mediated phosphatidylcholine turnover influences transcription factor Opi1p localization, affecting transcriptional regulation of phospholipid biosynthesis genes
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.34 0.34 0.29 0.29 0.07 0.19 0.09 0.05 0.08 – 0.06 0 0.4 0.4 0.38 0.38 0.38 0.38 0.35 0.36 0.45 0.38 0.37 0.41
Bud 0 0 0.12 0.11 0.15 0.11 0.12 0.12 0.13 – 0.16 0.08 0.07 0.09 0.1 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.07 0.08 0.1 0.1 0.05 0 0 0 0 – 0.05 0.05 0.1 0.11 0.22 0.1 0.13 0.1 0 0 0.06 0.07 0.07 0.11
Cytoplasm 0.14 0.17 0.14 0.17 0.13 0.18 0.18 0.2 0.1 – 0.1 0.15 0.2 0.19 0.19 0.22 0.16 0.17 0 0 0 0 0 0
Endoplasmic Reticulum 0.41 0.53 0.28 0.16 0.17 0.22 0.15 0.07 0.13 – 0.08 0 0.42 0.33 0.23 0.05 0.05 0.07 0.43 0.34 0.21 0.24 0.25 0.2
Endosome 0.05 0 0 0 0.07 0 0.05 0 0 – 0 0 0 0 0 0.07 0.05 0.08 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.15 0.27 0.21 0 0 0.05 0 0 0
Mitochondria 0.1 0.16 0.3 0.55 0.38 0.57 0.6 0.62 0.76 – 0.82 0.81 0.11 0.16 0.21 0.08 0.15 0.08 0.08 0.09 0.11 0.12 0.12 0.11
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.07 0 0.11 0.11 0.33 0.07 0.1 0.1 0.07 – 0.05 0.05 0 0 0 0.11 0.09 0.18 0 0 0.05 0 0 0
SpindlePole 0 0 0 0 0 0 0 0.05 0 – 0 0 0 0 0 0.09 0.14 0.12 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 77 127 79 73 20 53 39 26 40 – 20 3 50 111 122 62 64 73 110 159 156 69 111 139
Bud 10 14 33 29 42 31 50 68 61 – 53 31 9 24 31 3 4 5 0 2 0 0 2 1
Bud Neck 1 0 0 0 0 0 0 2 0 – 0 0 0 1 0 0 0 0 2 16 5 10 7 9
Bud Site 1 3 1 1 1 5 4 4 7 – 6 5 0 1 1 0 0 1 – – – – – –
Cell Periphery 16 32 26 26 14 12 14 15 18 – 17 21 13 30 70 16 22 20 11 14 20 12 20 38
Cytoplasm 32 63 37 43 38 52 77 115 49 – 34 60 25 53 60 37 27 33 2 6 1 3 8 6
Endoplasmic Reticulum 91 201 77 41 50 62 63 40 61 – 25 17 53 91 73 8 8 13 134 152 73 44 76 68
Endosome 12 2 12 6 20 5 21 23 3 – 0 10 1 4 0 11 9 16 4 11 10 5 6 9
Golgi 5 3 2 0 0 0 0 0 0 – 0 0 1 0 0 24 46 40 9 16 18 5 6 9
Mitochondria 23 62 82 139 109 164 259 352 367 – 271 321 14 45 67 14 26 15 25 38 37 21 37 35
Nucleus 1 0 1 2 1 0 0 3 1 – 0 1 2 0 0 0 2 1 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 1 0 0 0 – 1 2 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 1 1 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 15 5 29 29 96 20 43 58 36 – 18 18 4 12 10 18 15 35 4 3 16 2 7 7
SpindlePole 2 2 8 2 11 3 10 27 10 – 9 7 0 4 3 15 23 22 0 0 0 0 0 0
Vac/Vac Membrane 10 7 7 0 2 1 4 10 2 – 5 11 0 0 1 5 5 11 3 15 8 6 13 8
Unique Cell Count 224 377 271 254 289 286 429 569 480 332 394 126 279 318 165 168 191 313 443 352 184 304 338
Labelled Cell Count 296 521 394 391 404 409 584 743 655 460 508 172 376 438 213 251 286 313 443 352 184 304 338


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.1 6.0 5.4 5.1 5.1 4.8 4.6 4.4 4.0 – 3.9 3.7 5.5 5.7 5.4 8.6 9.3 9.9 6.3 6.3 6.6
Std Deviation (1e-4) 1.4 1.0 0.8 1.3 1.6 1.4 1.5 1.4 1.1 – 1.1 0.8 1.0 0.9 0.9 1.7 2.1 2.3 1.2 1.3 1.4
Intensity Change (Log2) – – – -0.06 -0.07 -0.16 -0.22 -0.29 -0.41 – -0.45 -0.54 0.05 0.08 0.02 0.69 0.8 0.88 0.24 0.24 0.29


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.1 -6.9 0 0 0 0 – 0 0 2.1 2.6 2.4 1.8 1.9 2.0
Bud -0.3 0.8 0 0 0 0 – 0 0 -1.5 -1.4 -0.9 -3.8 -3.6 -3.7
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 0.2 -2.2 0 0 0 0 – 0 0 0.2 0.4 4.1 0 1.1 0.3
Cytoplasm 1.0 -0.2 1.5 1.5 2.3 -1.4 – -1.3 0.6 1.6 1.7 1.7 2.4 0.7 1.1
Endoplasmic Reticulum -3.4 -3.1 0 0 0 0 – 0 0 2.7 1.1 -1.5 -6.0 -6.1 -5.8
Endosome -1.3 1.3 0 0 0 0 – 0 0 0 -2.1 -3.8 1.0 0.4 1.8
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 5.9 8.7 7.4
Mitochondria 5.7 1.9 0 0 0 0 – 0 0 -4.1 -3.9 -2.6 -5.3 -3.5 -5.8
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0.3 6.4 0 0 0 0 – 0 0 -2.5 -2.9 -3.7 0.1 -0.6 2.3
SpindlePole 0 0.6 0 0 0 0 – 0 0 0 -1.2 -1.8 2.8 4.3 3.7
Vacuole 0 0 0 0 -0.8 0 – -0.9 0.2 0 0 0 0 0 1.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.1914 4.7543 4.9386 4.8479 3.7366 4.5358 2.4291 3.3579 3.502 2.8633 2.3312 2.8331 4.2247 4.1868 4.3522 4.2006 3.8503 3.5147
Actin 0.1755 0.1349 0.2396 0.2338 0.166 0.1831 0.171 0.1213 0.1459 0.22 0.305 0.1427 0.2411 0.1918 0.2761 0.2681 0.3451 0.2437
Bud 0.0015 0.0021 0.0043 0.0032 0.0037 0.001 0.0212 0.0019 0.0152 0.0026 0.0006 0.0012 0.0008 0.0028 0.0154 0.0008 0.0029 0.0019
Bud Neck 0.0222 0.0108 0.0333 0.0438 0.0692 0.0983 0.0304 0.0091 0.0162 0.0094 0.0076 0.1034 0.0144 0.0088 0.0189 0.0521 0.0397 0.0693
Bud Periphery 0.006 0.004 0.0188 0.0292 0.0394 0.0039 0.0138 0.0018 0.006 0.0074 0.0013 0.0039 0.0023 0.0055 0.0186 0.0088 0.0222 0.0076
Bud Site 0.0134 0.106 0.0379 0.003 0.0456 0.0029 0.0547 0.1023 0.0241 0.0138 0.0026 0.002 0.013 0.0992 0.0693 0.0029 0.0131 0.0064
Cell Periphery 0.0315 0.0159 0.0286 0.0563 0.0123 0.0179 0.0298 0.031 0.0322 0.0236 0.0195 0.0303 0.0303 0.0312 0.0443 0.063 0.046 0.0207
Cytoplasm 0.1652 0.231 0.2119 0.2407 0.151 0.2681 0.1754 0.3491 0.2875 0.2735 0.1332 0.2599 0.1853 0.2062 0.1871 0.1097 0.1292 0.3406
Cytoplasmic Foci 0.0764 0.0884 0.0766 0.0279 0.0371 0.069 0.0866 0.0645 0.0744 0.0697 0.0989 0.0972 0.0777 0.0692 0.06 0.047 0.0752 0.0652
Eisosomes 0.0054 0.0017 0.0045 0.01 0.0047 0.0033 0.0055 0.0039 0.0037 0.0035 0.006 0.0028 0.0073 0.0065 0.0093 0.0242 0.0219 0.0032
Endoplasmic Reticulum 0.0654 0.0865 0.0992 0.0562 0.1124 0.1094 0.0495 0.0487 0.0698 0.151 0.1845 0.0945 0.0715 0.0888 0.0338 0.0962 0.0492 0.0612
Endosome 0.07 0.0579 0.0442 0.0377 0.0767 0.0489 0.0345 0.0277 0.0461 0.065 0.0287 0.0431 0.0694 0.0483 0.0221 0.0159 0.0287 0.0315
Golgi 0.0567 0.071 0.0596 0.0623 0.0525 0.0616 0.0211 0.0388 0.0682 0.0499 0.0889 0.0626 0.0589 0.0605 0.0441 0.0615 0.0812 0.0366
Lipid Particles 0.1589 0.1176 0.0696 0.0354 0.093 0.0767 0.1639 0.0659 0.0796 0.0738 0.0889 0.0889 0.0888 0.0573 0.058 0.0288 0.0752 0.0308
Mitochondria 0.015 0.0062 0.0165 0.0465 0.0514 0.0161 0.0076 0.0016 0.0253 0.0045 0.0021 0.0234 0.0055 0.0047 0.0045 0.0038 0.0108 0.0053
None 0.043 0.0405 0.0308 0.0618 0.052 0.0237 0.0968 0.1086 0.0787 0.0114 0.0037 0.0247 0.097 0.1074 0.1217 0.1955 0.0374 0.0579
Nuclear Periphery 0.0342 0.004 0.0045 0.0082 0.0031 0.0022 0.0034 0.0034 0.0091 0.0018 0.0017 0.0015 0.0048 0.0012 0.0013 0.0009 0.0017 0.0015
Nucleolus 0.0009 0.0005 0.0004 0.0003 0.0002 0.0002 0.0014 0.0007 0.0006 0.0002 0.0001 0.0002 0.0006 0.0003 0.0008 0.0002 0.0005 0.0003
Nucleus 0.0063 0.0012 0.0012 0.0017 0.0007 0.0008 0.0028 0.0014 0.0047 0.0007 0.0003 0.0008 0.0008 0.0005 0.0031 0.0003 0.0006 0.001
Peroxisomes 0.031 0.0121 0.0091 0.0017 0.0205 0.007 0.0186 0.0035 0.0045 0.0096 0.0236 0.0113 0.0207 0.0062 0.006 0.0163 0.0141 0.0087
Punctate Nuclear 0.0127 0.0021 0.0034 0.0007 0.0009 0.0011 0.0062 0.0113 0.002 0.0011 0.0011 0.0015 0.0031 0.0009 0.0018 0.0006 0.0024 0.0014
Vacuole 0.0055 0.0049 0.0051 0.0219 0.0052 0.004 0.0049 0.0032 0.005 0.0067 0.0013 0.0031 0.0053 0.0024 0.0035 0.0033 0.0023 0.0047
Vacuole Periphery 0.0032 0.0007 0.001 0.0175 0.0023 0.0009 0.001 0.0003 0.0012 0.0008 0.0004 0.0008 0.0014 0.0004 0.0004 0.0003 0.0007 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 38.4221 27.595 29.045 30.7228 25.8305 32.8212 34.1346 32.4543 31.86 37.4555
Translational Efficiency 0.4441 0.3639 0.3688 0.3567 0.2953 0.4868 0.3752 0.3564 0.4038 0.3427

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
276 1441 362 1500 1901 2201 148 827 2177 3642 510 2327

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 721.42 840.60 1289.38 1033.86 747.85 854.47 1058.61 996.16 744.50 848.98 1222.41 1020.46
Standard Deviation 100.55 119.62 158.29 138.12 106.46 116.87 124.15 140.38 106.09 118.16 182.28 140.09
Intensity Change Log 2 — 0.220580 0.837766 0.519130 — 0.192281 0.501350 0.413629 — 0.206245 0.676327 0.466394

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.126886* 0.106357* 0.067642 0.154216* 0.055433 0.073339 0.143464* 0.225286* 0.064492 0.086403 0.089646 0.179474*
Bud Neck 0.003441 0.006568 0.004769 0.007908 0.007209 0.010586 0.005407 0.012553 0.006731 0.008996 0.004954 0.009559
Bud Site 0.004693 0.013827 0.028709 0.036773 0.006969 0.019893 0.018263 0.043846 0.006680 0.017493 0.025677 0.039287
Cell Periphery 0.005833 0.021753 0.008977 0.014826 0.011845 0.019942 0.032142 0.049229 0.011083 0.020658 0.015699 0.027052
Cytoplasm 0.024645 0.092559 0.016463 0.049040 0.137849* 0.162988* 0.068001 0.040704 0.123497* 0.135122* 0.031419 0.046077
Cytoplasmic Foci 0.060158 0.063645 0.015813 0.056488 0.059275 0.065128 0.055849 0.023915 0.059387 0.064541 0.027431 0.044912
Eisosomes 0.013485 0.039433 0.004708 0.027504 0.056244 0.047635 0.031667 0.051943 0.050823 0.044390 0.012531 0.036189
Endoplasmic Reticulum 0.061964 0.091479 0.556150* 0.156461* 0.050428 0.082956 0.314148* 0.225455* 0.051891 0.086328 0.485922* 0.180981*
Endosome 0.036384 0.022462 0.037597 0.039419 0.012670 0.017424 0.017332 0.021082 0.015676 0.019417 0.031717 0.032902
Golgi 0.110287* 0.152833* 0.025036 0.091029 0.157675* 0.131646* 0.046584 0.038494 0.151668* 0.140029* 0.031289 0.072358
Lipid Particles 0.354935* 0.168623* 0.166674* 0.288422* 0.182214* 0.165394* 0.185859* 0.192637* 0.204112* 0.166672* 0.172241* 0.254380*
Mitochondria 0.013235 0.021579 0.000154 0.003803 0.025374 0.024466 0.000326 0.003365 0.023835 0.023324 0.000204 0.003647
Mitotic Spindle 0.001197 0.000316 0.001145 0.007651 0.000108 0.000756 0.000587 0.002202 0.000246 0.000582 0.000983 0.005714
None 0.000626 0.001011 0.000053 0.000374 0.002241 0.001484 0.000059 0.000335 0.002036 0.001297 0.000054 0.000360
Nuclear Periphery 0.000091 0.000093 0.000793 0.000250 0.000089 0.000095 0.000361 0.000180 0.000089 0.000094 0.000668 0.000225
Nuclear Periphery Foci 0.001973 0.000706 0.039926 0.006377 0.000418 0.000718 0.018833 0.003159 0.000615 0.000713 0.033805 0.005234
Nucleolus 0.000122 0.000085 0.000013 0.000076 0.000062 0.000105 0.000052 0.000030 0.000069 0.000097 0.000024 0.000060
Nucleus 0.003709 0.002240 0.001267 0.004870 0.004350 0.005391 0.007545 0.002008 0.004269 0.004144 0.003089 0.003853
Peroxisomes 0.174728* 0.190620* 0.002043 0.035645 0.226579* 0.164696* 0.028625 0.051002 0.220005* 0.174953* 0.009757 0.041103
Vacuole 0.000988 0.002395 0.021766 0.016290 0.002010 0.003939 0.024691 0.011596 0.001881 0.003328 0.022614 0.014622
Vacuole Periphery 0.000620 0.001415 0.000304 0.002580 0.000957 0.001419 0.000204 0.000977 0.000914 0.001417 0.000275 0.002010

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.51 3.87 -1.96 -6.22 -8.15 -4.40 -4.48 -16.92 -14.95 -3.86 -5.64 -2.77 -19.35 -15.88 -9.05
Bud Neck -1.90 -0.90 -2.95 -1.25 -3.36 -2.67 1.27 -3.11 -1.18 -4.09 -2.17 1.71 -2.67 -0.66 -5.31
Bud Site -6.02 -4.53 -11.25 -7.59 -1.22 -7.99 -4.34 -11.21 -6.85 -6.16 -8.98 -4.95 -14.81 -9.38 -2.95
Cell Periphery -7.91 -1.40 -5.80 3.50 -2.63 -4.92 -3.38 -10.63 -8.11 -2.60 -7.01 -1.87 -9.43 -3.58 -4.34
Cytoplasm -14.74 2.02 -5.82 9.90 -9.33 -4.82 6.82 20.47 26.06 2.75 -2.72 19.47 19.33 26.29 -3.82
Cytoplasmic Foci -0.34 5.69 0.51 1.89 -12.32 -2.06 0.27 12.05 14.00 3.99 -1.99 8.87 5.32 8.09 -5.02
Eisosomes -10.12 3.92 -5.40 4.48 -9.41 3.00 3.66 1.06 -1.05 -2.79 2.68 12.92 5.52 3.78 -8.35
Endoplasmic Reticulum -2.99 -24.93 -8.67 -8.27 21.17 -7.54 -10.00 -17.43 -13.89 3.13 -9.18 -27.66 -21.52 -15.61 18.54
Endosome 3.35 -0.29 -0.71 -6.90 -0.48 -4.08 -1.94 -4.30 -1.80 -1.21 -3.38 -6.80 -9.98 -7.99 -0.40
Golgi -4.77 10.23 2.28 11.35 -14.64 5.22 16.77 25.62 23.54 1.28 2.67 27.83 18.05 19.06 -11.55
Lipid Particles 9.86 8.84 3.42 -13.43 -9.13 2.81 -0.18 -1.10 -2.97 -0.37 6.68 3.09 -6.74 -13.44 -7.50
Mitochondria -2.95 5.78 4.02 9.85 -5.59 0.48 17.88 11.73 11.84 -2.42 0.32 18.77 14.45 16.60 -5.61
Mitotic Spindle 2.69 0.14 -4.51 -5.24 -4.61 -2.45 -3.50 -2.66 -1.73 -2.00 -1.96 -4.38 -5.75 -5.36 -4.93
None -0.87 1.91 0.84 2.10 -3.75 1.54 6.12 4.84 3.22 -1.68 1.89 6.31 5.18 3.96 -3.78
Nuclear Periphery -0.02 -5.75 -3.70 -3.36 4.22 -0.43 -4.89 -2.26 -2.17 2.84 -0.32 -6.57 -4.35 -4.20 4.79
Nuclear Periphery Foci 2.67 -8.01 -4.52 -6.55 6.96 -4.06 -5.32 -5.19 -4.59 4.49 -1.14 -9.44 -7.77 -7.63 7.99
Nucleolus 0.69 2.07 0.90 0.21 -2.96 -1.80 0.71 3.20 2.91 1.72 -1.28 4.93 0.63 1.55 -2.43
Nucleus 1.01 1.52 -0.74 -4.05 -5.00 -2.29 -2.89 5.73 6.86 4.75 0.18 1.87 0.55 0.43 -1.14
Peroxisomes -1.17 13.65 10.89 27.67* -17.00 9.71 29.91* 29.35* 22.28 -4.14 7.97 43.05* 35.90* 37.23* -14.22
Vacuole -3.67 -6.66 -10.71 -9.75 1.78 -4.01 -5.54 -7.24 -5.64 3.19 -4.14 -8.26 -12.25 -10.79 3.17
Vacuole Periphery -4.87 2.51 -3.72 -2.19 -4.40 -2.85 6.55 -0.05 1.20 -2.20 -3.93 6.28 -2.99 -1.60 -4.87
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Serine esterase; homolog of human neuropathy target esterase (NTE); Nte1p-mediated phosphatidylcholine turnover influences transcription factor Opi1p localization, affecting transcriptional regulation of phospholipid biosynthesis genes
Localization
Cell Percentages ER (49%)
Cell Cycle Regulation No
Subcompartmental Group ER-1

Nte1

Nte1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nte1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available