Standard name
Human Ortholog
Description Protein localized to COPII-coated vesicles; forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.05 0.06 0.1 0.06 0.06 0.08 0 0 – 0.05 0.05 0.09 0.1 0.06 0.05 0.08 0.14 0.09 0.05 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0.07 0 0.06 0.08 – 0.06 0.08 0.06 0 0.08 0.14 0.17 0.19 0.23 0 0 0 0 0 0
Cytoplasm 0.14 0.14 0.17 0.23 0.33 0.26 0.33 0.36 – 0.29 0.28 0.23 0.11 0.11 0.11 0.44 0.52 0.58 0 0 0 0 0 0
Endoplasmic Reticulum 0.82 0.88 0.79 0.61 0.25 0.53 0.35 0.2 – 0.25 0.21 0.39 0.85 0.85 0.84 0 0 0 0.86 0.9 0.89 0.81 0.84 0.81
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Golgi 0.07 0 0 0.08 0.05 0 0 0 – 0 0 0 0 0 0 0.06 0 0.05 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.07 0.13 0.2 0.2 – 0.28 0.43 0.4 0 0 0 0.13 0.09 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.14 0.35 0.11 0.17 0.25 – 0.18 0.12 0.08 0 0 0 0.29 0.1 0.08 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 16 8 23 9 15 22 13 21 – 19 17 36 35 25 23 9 11 7 15 4 6 15 10 13
Bud 3 0 2 0 9 8 10 15 – 16 21 14 8 1 0 2 2 1 2 0 0 2 2 2
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1
Bud Site 0 0 0 0 0 1 0 0 – 2 2 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 3 7 4 18 12 19 38 – 23 29 27 8 32 66 18 15 18 1 0 3 1 3 4
Cytoplasm 44 20 42 35 81 74 113 173 – 107 97 95 38 45 53 48 41 45 6 2 7 10 13 11
Endoplasmic Reticulum 264 122 191 93 61 154 119 93 – 92 74 165 289 349 396 1 3 0 283 128 221 309 277 289
Endosome 2 0 5 1 4 5 11 16 – 15 2 3 0 1 2 5 0 0 3 1 0 3 1 4
Golgi 22 2 10 12 12 0 2 3 – 0 0 2 7 10 7 6 3 4 6 2 3 10 6 4
Mitochondria 3 1 5 5 18 39 68 96 – 105 149 167 0 0 0 14 7 1 3 0 2 7 6 7
Nucleus 1 0 0 0 1 1 5 4 – 2 3 1 1 1 1 1 2 0 0 0 0 0 0 1
Nuclear Periphery 0 3 4 2 2 3 4 3 – 3 2 2 0 1 0 0 0 0 2 0 0 2 1 1
Nucleolus 0 0 0 0 0 0 1 1 – 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 1 1 – 3 0 0 0 0 0 1 1 0 0 0 0 0 0 0
Vac/Vac Membrane 11 4 9 21 88 32 59 117 – 68 43 33 9 14 9 31 8 6 3 2 0 11 4 6
Unique Cell Count 321 139 241 152 248 290 338 476 370 347 420 342 409 473 108 79 78 331 142 250 383 330 356
Labelled Cell Count 368 163 298 182 309 351 425 581 456 439 548 395 479 557 137 93 82 331 142 250 383 330 356


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 16.6 18.2 13.3 12.3 12.5 9.9 9.1 9.8 – 9.0 8.5 8.8 15.1 15.4 14.8 10.3 10.3 10.7 16.0 17.1 16.5
Std Deviation (1e-4) 4.1 3.2 2.8 2.4 5.8 2.7 2.5 2.7 – 2.4 2.1 2.2 2.9 2.9 2.6 2.0 2.0 2.1 3.4 3.5 3.5
Intensity Change (Log2) – – – -0.1 -0.09 -0.42 -0.54 -0.44 – -0.57 -0.64 -0.6 0.18 0.22 0.16 -0.37 -0.37 -0.3 0.27 0.37 0.32

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -1.3 -1.4 -0.8 -2.8 -2.7 – -2.1 -2.2 -0.4 0.3 -1.6 -2.4 -0.4 1.1 -0.1
Bud 0 2.1 0 0 1.9 – 2.5 3.2 2.0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 2.2 0.8 1.6 2.6 – 1.9 2.7 2.0 -0.4 2.6 4.6 4.6 4.9 5.8
Cytoplasm 1.4 3.9 2.2 4.3 5.2 – 3.2 3.0 1.6 -2.2 -2.3 -2.3 5.3 6.1 6.9
Endoplasmic Reticulum -3.9 -12.1 -6.3 -10.5 -15.4 – -13.2 -13.9 -9.9 1.6 2.0 1.5 -13.6 -11.9 -12.4
Endosome 0 0 0 0.9 1.0 – 1.3 0 0 0 0 0 0 0 0
Golgi 1.6 0.4 0 0 0 – 0 0 0 -1.5 -1.2 -2.2 0 0 0
Mitochondria 0 2.7 4.7 6.4 6.6 – 8.3 11.1 10.6 0 0 0 4.1 0 0
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 3.7 8.8 3.1 5.1 6.9 – 5.3 3.6 2.1 -0.8 -0.2 -1.5 6.8 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.9128 3.9231 2.7877 2.8534 2.4455 4.486 5.5041 5.4463 5.8215 4.9703 5.6248 5.616 4.5519 4.4084 4.4161 4.0716 3.8891 4.5464
Actin 0.0401 0.0078 0.0078 0.0119 0.0161 0.0073 0.0321 0.0142 0.0283 0.0287 0.0271 0.0117 0.0094 0.0096 0.0151 0.025 0.0053 0.0112
Bud 0.0011 0.0071 0.002 0.012 0.001 0.0019 0.0012 0.0078 0.0037 0.0009 0.001 0.0005 0.0006 0.006 0.0036 0.0026 0.0004 0.0021
Bud Neck 0.0058 0.0004 0.0008 0.0014 0.0007 0.0015 0.0013 0.0005 0.0007 0.0007 0.001 0.0049 0.0002 0.0007 0.0005 0.0003 0.0006 0.004
Bud Periphery 0.0014 0.0088 0.0037 0.0112 0.0008 0.0023 0.004 0.0195 0.0122 0.0096 0.003 0.0016 0.0039 0.0084 0.0126 0.0172 0.0017 0.0106
Bud Site 0.0243 0.0164 0.0052 0.0032 0.008 0.0006 0.0055 0.0065 0.0066 0.0006 0.0012 0.0005 0.0014 0.0248 0.0043 0.0008 0.0007 0.0004
Cell Periphery 0.0022 0.0033 0.0013 0.0038 0.0003 0.0008 0.0025 0.0035 0.0021 0.0041 0.0011 0.0008 0.0022 0.0027 0.0025 0.0027 0.0019 0.0016
Cytoplasm 0.1352 0.2078 0.2738 0.194 0.1849 0.2279 0.1653 0.2521 0.1651 0.2148 0.1342 0.219 0.1519 0.2137 0.1627 0.0803 0.1777 0.1721
Cytoplasmic Foci 0.0678 0.0246 0.0295 0.0356 0.0345 0.0173 0.0375 0.0121 0.0235 0.014 0.0383 0.0222 0.0186 0.0244 0.0225 0.024 0.0147 0.02
Eisosomes 0.0004 0.0005 0.0006 0.0001 0.0006 0.0001 0.0008 0.0003 0.0004 0.0006 0.0004 0.0002 0.0005 0.0003 0.0005 0.0008 0.0005 0.0003
Endoplasmic Reticulum 0.3737 0.3883 0.3693 0.309 0.3166 0.5515 0.3511 0.3467 0.4038 0.3339 0.3673 0.4327 0.5431 0.4057 0.4911 0.5584 0.4754 0.5254
Endosome 0.089 0.0406 0.0348 0.0629 0.0793 0.0729 0.0661 0.0348 0.0567 0.0493 0.0888 0.0557 0.031 0.04 0.0477 0.0346 0.061 0.0348
Golgi 0.0277 0.01 0.0165 0.0189 0.0604 0.0112 0.0171 0.0086 0.0167 0.0281 0.0469 0.0168 0.0086 0.0142 0.0116 0.0226 0.0115 0.0083
Lipid Particles 0.0289 0.0115 0.0148 0.034 0.0113 0.0075 0.0267 0.0152 0.0253 0.0052 0.0237 0.0121 0.0214 0.0292 0.0193 0.0198 0.0218 0.0139
Mitochondria 0.0167 0.0066 0.0128 0.0427 0.0475 0.0036 0.0111 0.0042 0.0038 0.0029 0.0065 0.003 0.0024 0.0025 0.0059 0.0154 0.0032 0.0028
None 0.0987 0.2314 0.2017 0.2358 0.1947 0.0727 0.2306 0.225 0.2151 0.2705 0.212 0.1956 0.1743 0.1629 0.1532 0.1543 0.1783 0.1588
Nuclear Periphery 0.022 0.0186 0.0085 0.0085 0.0086 0.0097 0.0156 0.0235 0.0169 0.0175 0.021 0.0104 0.0167 0.0258 0.0244 0.0203 0.0305 0.0181
Nucleolus 0.0028 0.0012 0.0004 0.0003 0.0005 0.0003 0.0005 0.0004 0.0004 0.0002 0.0003 0.0002 0.0003 0.0011 0.0004 0.0003 0.0001 0.0003
Nucleus 0.0285 0.0053 0.0023 0.0023 0.0032 0.0028 0.0026 0.0066 0.0033 0.0021 0.005 0.0032 0.0024 0.0101 0.0049 0.0022 0.0035 0.0038
Peroxisomes 0.0099 0.0007 0.0057 0.0026 0.0204 0.0003 0.0086 0.0008 0.0041 0.0005 0.005 0.0009 0.0007 0.0009 0.0009 0.0034 0.0003 0.0007
Punctate Nuclear 0.0097 0.0037 0.0033 0.0023 0.0024 0.0024 0.008 0.0016 0.002 0.002 0.004 0.0017 0.0021 0.0035 0.0023 0.0017 0.002 0.0028
Vacuole 0.011 0.0044 0.0042 0.0054 0.0067 0.004 0.0093 0.0141 0.0073 0.0104 0.0099 0.0049 0.007 0.0119 0.0109 0.0097 0.0063 0.0059
Vacuole Periphery 0.0032 0.0009 0.0008 0.0021 0.0017 0.0014 0.0026 0.0021 0.0022 0.0035 0.0024 0.0014 0.0015 0.0018 0.0031 0.0036 0.0026 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 41.1563 32.5998 31.102 41.1408 31.0709 28.1166 35.5514 41.6334 38.4877 47.3621
Translational Efficiency 0.8807 0.9552 1.1782 0.771 1.1338 1.3524 1.1256 0.7725 1.0122 0.8357

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2281 2049 118 654 2221 68 596 142 4502 2117 714 796

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 860.96 1073.31 1558.04 1041.07 808.48 905.08 910.06 1210.77 835.07 1067.91 1017.15 1071.34
Standard Deviation 163.06 307.56 328.70 296.60 150.78 241.66 160.26 396.00 159.30 307.10 311.80 323.22
Intensity Change Log 2 — 0.318049 0.855714 0.274049 — 0.162833 0.170750 0.582641 — 0.244963 0.564037 0.431740

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.004543 0.021394 0.005320 0.008868 0.003836 0.004783 0.011136 0.013492 0.004194 0.020860 0.010175 0.009693
Bud Neck 0.002171 0.003121 0.004050 0.010541 0.007948 0.008961 0.014618 0.010220 0.005021 0.003308 0.012871 0.010483
Bud Site 0.007618 0.039286 0.006740 0.052872 0.010054 0.026422 0.047097 0.017872 0.008819 0.038873 0.040427 0.046629
Cell Periphery 0.001443 0.003920 0.001935 0.003707 0.001213 0.000485 0.001798 0.007873 0.001329 0.003809 0.001821 0.004450
Cytoplasm 0.090350 0.076383 0.026057 0.219573 0.238843 0.206489 0.321134 0.114114 0.163607 0.080562 0.272368 0.200760
Cytoplasmic Foci 0.068501 0.040406 0.009118 0.050521 0.133119 0.126583 0.052215 0.035713 0.100380 0.043174 0.045093 0.047879
Eisosomes 0.000788 0.000543 0.000113 0.000338 0.000837 0.000224 0.000912 0.000286 0.000812 0.000533 0.000780 0.000329
Endoplasmic Reticulum 0.515678 0.596696 0.692796 0.274886 0.271248 0.293983 0.118958 0.584266 0.395092 0.586973 0.213794 0.330077
Endosome 0.034314 0.052756 0.052019 0.031394 0.038840 0.046753 0.012577 0.018597 0.036547 0.052563 0.019095 0.029111
Golgi 0.097817 0.042021 0.008491 0.010238 0.055202 0.035923 0.003408 0.009064 0.076794 0.041825 0.004248 0.010028
Lipid Particles 0.111864 0.065070 0.056682 0.036267 0.109380 0.039474 0.060612 0.052972 0.110638 0.064248 0.059963 0.039247
Mitochondria 0.018754 0.016119 0.000203 0.006706 0.023630 0.011075 0.000985 0.000364 0.021159 0.015957 0.000855 0.005575
Mitotic Spindle 0.000424 0.001886 0.005656 0.027861 0.001254 0.003483 0.010459 0.005946 0.000833 0.001937 0.009666 0.023951
None 0.011830 0.007364 0.000091 0.003858 0.009274 0.000532 0.007948 0.001430 0.010569 0.007145 0.006649 0.003425
Nuclear Periphery 0.000729 0.000283 0.006704 0.003714 0.003029 0.001153 0.001782 0.001057 0.001864 0.000311 0.002596 0.003240
Nuclear Periphery Foci 0.007066 0.004397 0.066146 0.047827 0.006353 0.005943 0.027045 0.004515 0.006714 0.004446 0.033507 0.040100
Nucleolus 0.000281 0.000360 0.000328 0.000473 0.000730 0.000328 0.000322 0.000216 0.000503 0.000359 0.000323 0.000427
Nucleus 0.005961 0.007675 0.008947 0.047855 0.035611 0.043624 0.134318 0.035976 0.020588 0.008829 0.113598 0.045736
Peroxisomes 0.010435 0.004285 0.000710 0.002768 0.009644 0.008036 0.003717 0.001561 0.010045 0.004405 0.003220 0.002553
Vacuole 0.006294 0.012149 0.046526 0.156160 0.034602 0.134093 0.166687 0.083818 0.020259 0.016066 0.146829 0.143254
Vacuole Periphery 0.003138 0.003887 0.001366 0.003572 0.005354 0.001655 0.002272 0.000647 0.004231 0.003815 0.002123 0.003050

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -8.69 -0.35 -1.33 5.30 -0.53 -0.20 -0.28 -1.05 -0.90 -1.00 -9.02 -0.17 -1.81 4.59 -1.62
Bud Neck -2.04 -1.79 -7.57 -6.68 -3.81 -0.36 -3.48 -0.72 -0.45 0.24 3.45 -6.38 -4.61 -6.13 0.20
Bud Site -11.79 -0.09 -7.81 -1.37 -7.16 -1.96 -3.92 -1.48 0.86 1.06 -11.76 -4.20 -7.76 -0.59 -3.85
Cell Periphery -7.20 -1.31 -3.04 2.05 -1.57 3.52 2.27 -2.64 -2.97 -2.86 -7.60 2.51 -4.13 0.37 -4.86
Cytoplasm 2.49 6.07 -11.92 -12.82 -13.66 0.59 0.35 4.79 2.19 4.22 15.39 -3.76 -4.67 -12.27 -0.83
Cytoplasmic Foci 9.17 17.26 5.34 -1.33 -8.45 0.49 24.55 10.36 3.91 -1.19 20.05 24.25 14.36 -0.49 -4.43
Eisosomes 2.93 8.55 5.61 3.57 -2.73 6.85 4.42 6.51 -0.69 1.22 4.31 5.77 7.96 3.86 0.73
Endoplasmic Reticulum -6.75 -4.72 20.25 24.88 13.48 -0.04 24.30 -6.58 -3.98 -12.60 -18.40 19.44 9.30 20.34 -6.25
Endosome -8.78 -2.96 4.13 10.56 4.43 -0.58 19.15 5.91 2.81 -3.56 -8.15 14.06 6.53 11.89 -4.45
Golgi 14.31 22.40 25.08 13.55 0.38 1.44 23.09 15.95 1.67 -3.81 12.02 35.41 28.87 14.10 -3.85
Lipid Particles 9.70 4.21 17.04 7.97 2.16 5.65 17.18 5.36 -0.70 -2.20 11.68 18.37 18.90 7.00 -0.82
Mitochondria 1.35 14.92 7.62 5.72 -3.42 1.88 17.57 17.83 1.44 1.67 3.07 22.82 12.01 6.63 -3.19
Mitotic Spindle -3.22 -1.77 -6.13 -5.76 -3.60 -1.06 -4.21 -0.96 -0.61 0.59 -2.42 -4.69 -6.05 -5.71 -3.05
None 2.95 10.04 5.08 2.68 -2.53 7.69 3.23 6.00 -1.22 3.45 2.77 6.28 5.91 3.10 1.04
Nuclear Periphery 3.88 -4.21 -5.69 -6.70 1.99 3.61 1.28 3.09 -0.01 3.01 6.49 -3.52 -2.77 -6.85 -0.21
Nuclear Periphery Foci 3.66 -5.76 -7.27 -7.91 2.38 0.46 -3.52 1.40 0.50 4.02 3.88 -6.30 -7.18 -7.82 -2.88
Nucleolus -0.77 -0.22 -2.03 -0.70 -0.60 4.11 4.08 6.39 0.81 1.51 0.63 1.46 0.12 -0.48 -0.91
Nucleus -1.71 -1.30 -11.65 -11.11 -5.08 -0.91 -20.24 -1.21 -0.21 12.73 8.93 -20.13 -8.58 -11.03 14.81
Peroxisomes 7.29 10.93 9.69 3.82 -2.33 0.83 11.77 11.66 2.39 -0.23 9.44 14.54 13.89 4.60 -1.53
Vacuole -5.60 -4.80 -21.23 -20.65 -13.40 -4.26 -23.37 -4.30 1.48 10.93 2.04 -23.36 -20.22 -20.43 3.65
Vacuole Periphery -1.60 3.39 0.85 1.78 -1.64 8.67 7.53 15.80 2.71 0.27 0.93 6.86 3.89 2.48 -2.12
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein localized to COPII-coated vesicles; forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein
Localization
Cell Percentages ER (75%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Erv41

Erv41


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Erv41-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available