Standard name
Human Ortholog
Description DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; relocalizes to the cytosol in response to hypoxia; not essential for viability
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.05 0 0 0.05 0 0 0 0 0.06 0.12 0.16 0.11 0.1 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.08 0 0 0 0.05 0.09 0.08 0.4 0.26 0.24 0.31 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.94 0.96 0.93 0.95 0.92 0.92 0.9 0.88 0.83 0.82 0.81 0.8 0.87 0.86 0.8 0.76 0.78 0.87 0.95 0.91 0.92 0.85 0.74 0.46
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0.1 0.1 0.11 0.12 0 0 0 0.05 0 0.07 0 0 0 0 0.05 0.11
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0.06 0.14 0.24
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 1 0 3 3 2 2 5 0 0 0 0 0 0 0 2 1 0 0 2
Bud Neck 0 0 0 0 0 0 1 5 2 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Bud Site 0 0 0 0 0 2 2 6 9 10 16 17 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 4 5 8 6 12 11 11 19 7 14 12 12 6 23 33 7 6 2 0 1 1 1 3 4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 3
Endosome 0 1 2 0 4 0 3 1 0 0 0 0 1 0 1 2 1 0 0 2 2 1 0 7
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2 19 1 1 0 18 32 33 127 103 84 131 1 1 1 0 1 2 1 1 0 0 0 3
Nucleus 116 232 231 186 233 308 319 353 265 323 284 333 82 163 165 48 47 65 123 224 230 85 113 79
Nuclear Periphery 0 0 0 0 1 4 3 2 4 6 2 6 0 1 1 0 0 2 0 0 0 0 1 2
Nucleolus 4 0 3 1 0 6 11 15 31 40 39 49 1 1 2 3 0 5 0 2 2 2 7 19
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0
SpindlePole 0 1 1 1 1 3 9 6 3 5 3 8 0 1 3 0 0 1 0 1 0 0 2 3
Vac/Vac Membrane 3 0 4 1 7 2 6 6 2 4 5 2 4 3 7 3 4 2 2 6 8 6 21 41
Unique Cell Count 123 242 248 195 254 333 355 401 321 396 349 418 94 189 206 63 60 75 130 247 250 101 154 172
Labelled Cell Count 129 258 250 196 258 355 397 449 453 508 447 563 95 193 216 64 60 81 130 247 250 101 154 172


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.6 6.1 8.3 7.8 7.4 5.8 5.5 5.8 4.6 4.9 5.0 4.8 7.8 7.4 7.1 8.8 10.0 10.3 9.1 9.2 8.7
Std Deviation (1e-4) 2.8 1.1 1.4 1.4 1.6 1.1 1.2 1.4 1.1 1.1 1.1 0.9 1.6 1.5 1.7 4.1 3.1 3.0 1.4 1.4 1.8
Intensity Change (Log2) – – – -0.08 -0.17 -0.52 -0.6 -0.51 -0.85 -0.74 -0.74 -0.8 -0.09 -0.17 -0.21 0.1 0.28 0.32 0.14 0.15 0.08

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 3.4 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.1 0.9 0.1 -0.1 0.9 -0.8 0.2 0.1 -0.3 0 3.6 4.7 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 3.4 4.6 4.3 0 8.6 8.2 0 0 0 0 0 0 0
Nucleus 1.0 -0.6 -0.3 -1.4 -2.1 -3.7 -4.1 -4.1 -4.7 -1.8 -2.4 -4.1 -4.0 -3.5 -1.8
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 1.5 1.9 0 4.4 4.7 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0.9 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.9038 3.1198 3.2204 2.9352 3.2519 3.0399 6.4392 7.2953 7.4512 6.7496 6.5695 6.8108 4.5174 4.8003 4.4368 4.6359 3.8484 4.5037
Actin 0 0 0 0 0 0.0001 0.0012 0 0.0055 0 0.0007 0.0002 0.0105 0 0.008 0.0012 0.0025 0.0012
Bud 0 0 0 0 0 0 0.0002 0 0.0003 0.0001 0.0002 0.0001 0.0002 0 0.0006 0.0001 0.0002 0
Bud Neck 0 0 0 0 0.0002 0.0004 0.0005 0 0.001 0.0002 0.0011 0.0006 0.0008 0 0.0014 0.0001 0.0002 0.0003
Bud Periphery 0 0 0 0 0 0 0.0004 0 0.0006 0.0002 0.0006 0.0001 0.0003 0 0.0013 0.0001 0.0006 0.0001
Bud Site 0 0 0 0 0 0 0.0003 0 0.0023 0.0002 0.0003 0.0001 0.0019 0 0.0033 0.001 0.0015 0
Cell Periphery 0 0 0 0 0 0 0.0001 0 0.0003 0.0001 0.0002 0 0.0001 0 0.0004 0 0.0002 0
Cytoplasm 0 0.0001 0 0 0 0.0001 0.0175 0 0.0138 0.0001 0.0008 0.0013 0.0002 0.0001 0.0004 0.0001 0.0001 0.0002
Cytoplasmic Foci 0 0 0 0 0 0.002 0.0023 0 0.0104 0 0.0002 0.0012 0.0123 0 0.0062 0.0075 0.0011 0.0001
Eisosomes 0 0 0 0 0 0 0 0 0.0001 0 0 0 0.0001 0 0.0001 0 0.0002 0.0002
Endoplasmic Reticulum 0 0 0 0 0 0 0.007 0 0.0063 0 0.0015 0.0003 0.0003 0 0.0004 0 0.0002 0.0001
Endosome 0 0 0 0 0 0.001 0.0224 0 0.0218 0.0001 0.0008 0.0083 0.0081 0 0.0042 0.006 0.0022 0.0002
Golgi 0 0 0 0 0 0.0003 0.0042 0 0.0055 0 0.0001 0.0004 0.006 0 0.0038 0.0059 0.0024 0.0001
Lipid Particles 0 0 0 0 0 0.0005 0.0026 0 0.0217 0 0.0006 0.0004 0.0218 0 0.0106 0.004 0.0447 0.0002
Mitochondria 0.0001 0.0001 0 0.0001 0.0001 0.0001 0.0018 0 0.0045 0.0006 0.0025 0.0008 0.0033 0.0001 0.0124 0.0034 0.042 0.0003
None 0 0 0 0 0 0.0001 0.0065 0 0.007 0 0.0004 0.0003 0.0003 0 0.0006 0 0.0002 0.0044
Nuclear Periphery 0.0001 0.001 0.0006 0.0006 0.0004 0.0002 0.019 0.0007 0.0132 0.0007 0.0286 0.0038 0.0013 0.0026 0.0015 0.0002 0.0006 0.0005
Nucleolus 0.0105 0.0099 0.0071 0.0057 0.0484 0.0261 0.0099 0.0057 0.0052 0.0352 0.0329 0.0225 0.0098 0.0109 0.0057 0.007 0.0256 0.0217
Nucleus 0.9891 0.9868 0.992 0.9933 0.9501 0.9678 0.8952 0.9934 0.8662 0.9614 0.9214 0.9555 0.9043 0.9858 0.9274 0.9569 0.8686 0.9696
Peroxisomes 0 0 0 0 0 0.0006 0.0002 0 0.0028 0 0.0001 0.0005 0.0132 0 0.0063 0.0059 0.0047 0.0001
Punctate Nuclear 0.0001 0.002 0.0002 0.0001 0.0007 0.0007 0.0043 0.0001 0.007 0.0001 0.0041 0.0028 0.0043 0.0001 0.0022 0.0002 0.0003 0.0003
Vacuole 0 0 0 0 0 0 0.0034 0 0.0034 0.0008 0.0014 0.0004 0.0005 0.0001 0.0018 0.0002 0.0009 0.0001
Vacuole Periphery 0 0 0 0 0 0 0.0011 0 0.0013 0.0003 0.0018 0.0004 0.0004 0.0001 0.0015 0.0001 0.0009 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.2808 34.3317 27.4353 28.3327 37.3453 22.1444 25.0332 24.3299 21.4018 26.3078
Translational Efficiency 1.4074 1.1583 1.2191 1.025 1.0794 1.6409 0.9461 1.242 1.037 1.2199

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1317 1066 2231 1741 1802 2233 246 1778 3119 3299 2477 3519

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 708.54 914.99 1007.68 1018.04 818.20 1009.10 1131.50 1101.60 771.90 978.69 1019.98 1060.26
Standard Deviation 156.23 155.27 176.54 160.59 114.08 137.05 154.56 183.28 144.08 149.80 178.37 177.42
Intensity Change Log 2 — 0.368907 0.508116 0.522873 — 0.302544 0.467711 0.429075 — 0.333722 0.486603 0.473365

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000366 0.000602 0.000437 0.000993 0.000200 0.000273 0.000960 0.000577 0.000270 0.000379 0.000489 0.000783
Bud Neck 0.002942 0.007393 0.016339 0.022602 0.004098 0.007127 0.008570 0.016888 0.003610 0.007213 0.015567 0.019715
Bud Site 0.001879 0.000954 0.000888 0.005251 0.000415 0.001508 0.000756 0.001263 0.001033 0.001329 0.000874 0.003236
Cell Periphery 0.000495 0.000191 0.000090 0.000226 0.000098 0.000238 0.000036 0.000086 0.000266 0.000223 0.000084 0.000156
Cytoplasm 0.016537 0.002152 0.001254 0.017124 0.001550 0.001811 0.000266 0.002678 0.007878 0.001921 0.001156 0.009825
Cytoplasmic Foci 0.002555 0.000143 0.000011 0.002227 0.000307 0.000258 0.000016 0.000023 0.001256 0.000220 0.000011 0.001113
Eisosomes 0.000034 0.000032 0.000029 0.000034 0.000017 0.000039 0.000044 0.000028 0.000024 0.000037 0.000031 0.000031
Endoplasmic Reticulum 0.005321 0.006225 0.002806 0.004685 0.003517 0.006276 0.004927 0.003338 0.004279 0.006260 0.003017 0.004005
Endosome 0.000563 0.000313 0.000088 0.003335 0.000213 0.001248 0.000069 0.000116 0.000361 0.000946 0.000086 0.001708
Golgi 0.000387 0.000072 0.000035 0.001493 0.000063 0.000213 0.000048 0.000042 0.000200 0.000168 0.000036 0.000760
Lipid Particles 0.000343 0.000077 0.000013 0.000918 0.000082 0.000240 0.000050 0.000028 0.000192 0.000187 0.000017 0.000469
Mitochondria 0.001001 0.000755 0.000854 0.004242 0.000368 0.001888 0.001092 0.001333 0.000636 0.001522 0.000877 0.002772
Mitotic Spindle 0.000413 0.000088 0.000213 0.030525 0.000540 0.001508 0.000039 0.000742 0.000486 0.001050 0.000196 0.015477
None 0.051679 0.004020 0.001446 0.011178 0.003906 0.002806 0.000810 0.001974 0.024078 0.003198 0.001382 0.006528
Nuclear Periphery 0.000409 0.000322 0.000238 0.002568 0.000237 0.000922 0.000169 0.000397 0.000310 0.000728 0.000231 0.001471
Nuclear Periphery Foci 0.001869 0.000545 0.000034 0.001454 0.000174 0.000450 0.000027 0.000153 0.000890 0.000481 0.000034 0.000797
Nucleolus 0.019847 0.016707 0.005125 0.008665 0.017067 0.014193 0.009989 0.005104 0.018241 0.015005 0.005608 0.006866
Nucleus 0.891098 0.958194 0.969524 0.873652 0.966364 0.954948 0.970291 0.963977 0.934583 0.955997 0.969600 0.919289
Peroxisomes 0.000661 0.000369 0.000072 0.000598 0.000118 0.000263 0.000439 0.000092 0.000347 0.000297 0.000108 0.000342
Vacuole 0.001220 0.000670 0.000419 0.006401 0.000512 0.002654 0.001305 0.001030 0.000811 0.002013 0.000507 0.003687
Vacuole Periphery 0.000378 0.000177 0.000085 0.001828 0.000154 0.001136 0.000097 0.000132 0.000249 0.000826 0.000086 0.000971

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.87 -2.65 -11.81 -5.86 -11.26 -3.14 -13.45 -13.22 -10.96 4.84 -3.42 -10.90 -17.16 -12.36 -10.67
Bud Neck -6.65 -15.86 -15.36 -11.57 -4.39 -4.16 -4.70 -15.99 -11.75 -7.33 -6.81 -15.86 -21.68 -16.12 -5.01
Bud Site 1.77 1.74 -4.19 -6.84 -6.98 -3.69 -3.58 -6.55 -0.73 -4.29 -0.94 0.21 -6.34 -5.75 -7.68
Cell Periphery 4.26 6.57 5.17 0.45 -4.86 -2.52 3.30 0.58 2.83 -5.24 0.97 6.26 4.74 2.41 -3.89
Cytoplasm 6.74 7.43 0.56 -7.91 -8.97 -0.26 3.31 -2.16 -1.55 -5.24 5.91 7.39 -0.89 -7.63 -9.55
Cytoplasmic Foci 4.31 4.63 2.37 -3.44 -4.16 0.54 1.64 1.57 3.34 -2.04 4.05 4.87 2.45 -2.56 -4.21
Eisosomes 0.73 1.85 -0.15 -1.28 -3.59 -8.56 -8.55 -8.45 3.72 4.69 -5.50 -3.47 -4.67 2.30 -1.27
Endoplasmic Reticulum -1.79 7.81 0.72 2.43 -7.53 -7.92 -1.80 0.32 8.35 1.90 -6.74 6.19 0.21 6.96 -6.09
Endosome 2.02 5.11 -3.16 -3.81 -4.45 -3.16 2.78 1.52 3.44 -3.39 -2.51 5.65 -3.09 -0.33 -4.55
Golgi 1.68 1.88 -1.22 -2.49 -2.62 -1.81 0.38 0.31 2.02 -0.31 0.42 2.00 -1.38 -1.75 -2.66
Lipid Particles 3.48 4.51 -1.26 -3.00 -3.43 -1.25 0.98 1.07 1.62 0.35 0.16 4.82 -1.27 -1.13 -3.57
Mitochondria 0.78 0.30 -5.26 -7.36 -6.96 -3.13 -7.86 -8.22 0.55 -2.62 -2.50 -2.08 -8.00 -2.83 -7.96
Mitotic Spindle 1.33 0.45 -8.47 -8.61 -8.53 -1.40 1.08 -1.00 0.65 -3.11 -1.25 0.74 -8.40 -7.91 -8.68
None 10.75 11.54 9.56 -3.75 -7.35 1.37 4.15 2.45 1.68 -4.25 10.62 11.75 9.31 -3.54 -7.76
Nuclear Periphery 0.51 1.74 -5.04 -5.08 -5.58 -2.44 0.81 -3.37 1.51 -4.72 -2.15 1.13 -5.71 -2.38 -6.17
Nuclear Periphery Foci 2.25 3.61 1.91 -0.92 -4.63 -1.64 2.49 0.15 1.63 -1.65 1.83 3.89 1.65 -0.49 -4.86
Nucleolus 1.80 10.03 5.95 3.87 -4.14 1.90 3.38 7.31 6.70 2.09 2.88 11.85 9.07 6.88 -2.88
Nucleus -10.53 -12.61 0.99 13.25 15.93 3.36 -0.76 3.69 -0.19 3.93 -6.39 -10.77 3.65 10.71 15.64
Peroxisomes 0.93 1.98 0.91 -0.01 -3.48 -2.62 -6.73 0.05 2.68 6.93 0.40 1.87 0.75 0.80 -3.06
Vacuole 2.48 3.99 -7.41 -8.10 -8.41 -3.59 -1.73 -2.70 1.14 -0.66 -2.86 1.91 -7.89 -4.63 -8.52
Vacuole Periphery 1.87 2.78 -2.53 -3.51 -3.88 -3.51 1.23 0.36 3.59 -1.19 -2.97 3.18 -2.59 0.99 -4.04
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; relocalizes to the cytosol in response to hypoxia; not essential for viability
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Dat1

Dat1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dat1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available