Standard name
Human Ortholog
Description Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes; relative distribution to nucleus increases upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.86 0.79 0.2 0.48 0.42 0.43 – 0.2 0.26 0.16 0.27 0 0.62 0.33 0.54 0.69 0.74 0.96 0.77 0.75 0.42 0.77 0.8
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.13 0.15 – 0.34 0.34 0.46 0.21 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0.05 0.1 0.62 0.25 0.28 0.3 – 0.43 0.36 0.39 0.32 0.84 0.17 0.39 0.13 0.08 0.05 0 0.11 0.11 0.21 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0.05 0 0.11 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0
Vac/Vac Membrane 0 0.1 0.11 0.17 0.27 0.24 0.19 – 0.17 0.16 0.16 0.25 0.07 0.22 0.26 0.37 0.31 0.23 0 0.05 0 0.11 0.05 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 0 2 0 0 – 0 0 0 1 0 0 0 1 0 0 1 1 0 0 2 3
Bud 0 2 1 0 0 2 6 – 5 9 7 8 0 0 0 0 0 0 0 4 4 14 10 10
Bud Neck 0 0 1 1 0 0 1 – 0 0 1 0 0 0 0 0 0 0 0 3 1 2 3 3
Bud Site 0 0 0 0 0 1 1 – 5 1 2 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 1 13 1 3 2 5 – 2 1 1 1 0 3 0 7 4 10 0 0 0 0 0 0
Cytoplasm 185 285 351 63 252 168 234 – 112 140 88 145 15 263 139 169 159 182 186 287 372 91 319 343
Endoplasmic Reticulum 1 2 4 0 3 1 6 – 2 1 0 0 0 0 1 10 8 6 0 0 0 3 12 10
Endosome 0 2 0 6 23 16 15 – 5 3 3 22 3 23 20 13 5 3 0 3 5 6 4 3
Golgi 0 0 1 0 0 0 0 – 0 0 0 0 0 0 0 2 0 1 0 2 2 0 0 1
Mitochondria 2 7 0 8 13 52 82 – 189 183 256 112 16 3 6 4 1 0 0 5 8 3 7 4
Nucleus 4 16 43 196 133 112 165 – 237 198 214 173 305 73 163 42 18 12 1 39 55 45 14 11
Nuclear Periphery 0 0 0 0 1 0 1 – 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 0 0 0 1 1 4 2 – 20 14 26 23 40 2 13 0 1 1 0 0 6 7 4 3
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
SpindlePole 0 0 1 0 1 0 0 – 1 1 1 4 0 0 0 0 0 0 0 2 12 13 6 4
Vac/Vac Membrane 0 34 50 55 144 94 102 – 93 88 89 136 25 95 107 115 72 58 1 18 21 25 22 24
Unique Cell Count 190 332 445 318 529 398 541 551 543 553 544 365 424 416 313 231 247 194 372 499 219 415 431
Labelled Cell Count 193 350 465 331 576 452 620 671 639 688 628 404 462 449 363 268 273 194 372 499 219 415 431


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.4 6.4 7.5 6.9 7.4 6.1 6.2 – 5.5 5.2 4.8 5.7 7.5 7.3 7.3 9.6 9.9 9.7 6.8 6.7 7.4
Std Deviation (1e-4) 0.9 1.1 0.8 1.0 1.1 1.1 1.1 – 1.0 0.9 0.8 0.9 1.8 1.5 1.3 2.1 1.7 1.6 1.1 1.6 2.9
Intensity Change (Log2) – – – -0.12 -0.03 -0.3 -0.27 – -0.44 -0.52 -0.66 -0.4 -0.01 -0.04 -0.03 0.36 0.4 0.36 -0.14 -0.17 -0.02

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery -2.6 -2.9 -2.7 -2.3 – -3.3 -3.6 0 -3.6 -3.3 -2.4 -3.5 -0.6 -0.9 0.8
Cytoplasm -16.1 -10.0 -10.9 -11.3 – -18.4 -16.6 -19.9 -16.3 -21.3 -5.5 -13.5 -7.3 -2.9 -1.6
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 2.3 0 0
Endosome 0 4.5 4.3 3.5 – 0 0 0 4.3 0 5.0 4.7 4.3 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 3.3 7.9 8.6 – 13.7 13.6 0 10.2 4.5 0 0 0 0 0
Nucleus 15.3 6.3 6.9 8.0 – 11.6 9.8 10.4 8.4 21.1 3.3 10.1 1.6 -0.8 -2.2
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 4.1 3.4 0 4.4 7.2 0 3.8 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 2.4 6.2 4.8 3.3 – 2.5 2.2 2.2 5.5 -2.1 4.4 5.5 8.4 6.4 4.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.0055 3.8106 3.5088 3.0571 3.1196 3.3475 3.7862 5.3628 4.6566 4.4095 4.3594 4.6863 4.2463 5.1124 4.7479 4.3088 3.6164 4.5026
Actin 0.0503 0.0032 0.0034 0.0149 0.0212 0.001 0.0319 0.0021 0.0105 0.0001 0.0295 0.001 0.0067 0.0008 0.0009 0.0003 0.0005 0.0006
Bud 0.0023 0.0039 0.001 0.0023 0.0017 0.0047 0.0015 0.0042 0.003 0.0004 0.0002 0.0016 0.0004 0.0001 0.0001 0.0007 0.0002 0.0039
Bud Neck 0.0015 0.0015 0.0031 0.0006 0.0017 0.0105 0.0025 0.0016 0.0009 0.0008 0.0007 0.0079 0.0002 0.0002 0.0004 0.0022 0.0007 0.0073
Bud Periphery 0.0029 0.0015 0.0012 0.0013 0.0013 0.004 0.001 0.0021 0.0028 0.0001 0.0001 0.0008 0.0002 0 0 0.0003 0 0.0033
Bud Site 0.0063 0.0379 0.0286 0.0071 0.0021 0.0021 0.021 0.0255 0.005 0.0008 0.0004 0.0008 0.0008 0.0006 0.0004 0.0002 0.0001 0.0016
Cell Periphery 0.0005 0.0004 0.0005 0.0001 0.0001 0.0003 0.0004 0.0005 0.0005 0 0 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0003
Cytoplasm 0.2851 0.544 0.3733 0.3667 0.4021 0.4511 0.3717 0.4715 0.4016 0.4364 0.3595 0.3926 0.5081 0.9928 0.7029 0.545 0.9324 0.7575
Cytoplasmic Foci 0.0529 0.02 0.0136 0.0691 0.0337 0.0024 0.0565 0.0035 0.0075 0.0008 0.0064 0.0063 0.024 0.0008 0.0011 0.0019 0.0011 0.0031
Eisosomes 0.0005 0 0.0001 0.0001 0.0001 0 0.0002 0 0.0001 0 0.0001 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0089 0.0035 0.0046 0.0031 0.0045 0.0025 0.0063 0.0021 0.004 0.0005 0.001 0.0028 0.0161 0.0007 0.0023 0.0015 0.0018 0.0142
Endosome 0.0568 0.0071 0.0245 0.0534 0.0281 0.002 0.0336 0.0019 0.0183 0.0003 0.0023 0.0022 0.3252 0.0002 0.0003 0.0013 0.0004 0.0021
Golgi 0.015 0.0011 0.0075 0.0249 0.022 0.0002 0.0111 0.0004 0.0019 0 0.0078 0.0002 0.093 0 0.0001 0.0001 0 0.0002
Lipid Particles 0.0198 0.0012 0.0089 0.0274 0.0025 0.0001 0.0168 0.0001 0.0022 0 0.0071 0.0001 0.0038 0 0 0 0 0.0001
Mitochondria 0.0259 0.001 0.0063 0.0194 0.01 0.0007 0.0037 0.0005 0.0052 0.0003 0.0011 0.0127 0.0055 0 0.0002 0.0002 0.0001 0.0003
None 0.015 0.0031 0.0041 0.002 0.0024 0.0011 0.0703 0.0068 0.0079 0.0006 0.0008 0.0139 0.002 0.0015 0.0034 0.0014 0.0034 0.0288
Nuclear Periphery 0.0202 0.0073 0.0058 0.0046 0.0107 0.0076 0.0108 0.0082 0.006 0.0044 0.0065 0.0059 0.0043 0.0004 0.0047 0.0055 0.0044 0.0047
Nucleolus 0.0121 0.0026 0.0039 0.0008 0.0011 0.0054 0.0027 0.0025 0.0024 0.0016 0.0034 0.0046 0 0 0.0002 0.0004 0 0.0006
Nucleus 0.3722 0.3391 0.4937 0.3539 0.3859 0.4899 0.3304 0.4257 0.5013 0.5509 0.5383 0.5378 0.0009 0.0015 0.2809 0.4336 0.0535 0.1642
Peroxisomes 0.029 0.0057 0.0035 0.0438 0.0614 0.0001 0.0076 0.0002 0.0029 0 0.0308 0.0001 0.0004 0 0 0 0 0.0001
Punctate Nuclear 0.0124 0.0073 0.0031 0.002 0.0053 0.0094 0.0145 0.0372 0.0069 0.0014 0.0031 0.0052 0.0004 0.0001 0.0019 0.0038 0.0002 0.0022
Vacuole 0.0071 0.0075 0.0084 0.0019 0.0016 0.0044 0.0046 0.0029 0.0069 0.0006 0.0006 0.003 0.0038 0.0001 0.0002 0.0015 0.0009 0.0046
Vacuole Periphery 0.0034 0.0009 0.0009 0.0007 0.0006 0.0006 0.0008 0.0003 0.0021 0.0001 0.0002 0.0004 0.0039 0 0 0.0002 0.0002 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 19.0422 14.9239 10.7281 21.7011 19.616 10.9497 25.6994 25.7793 17.776 27.9583
Translational Efficiency 1.4883 1.827 1.7955 0.8763 1.2786 3.1763 1.1078 0.957 1.6233 1.1329

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
107 1085 1497 979 1468 984 2095 154 1575 2069 3592 1133

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 761.09 894.82 1129.16 1029.78 836.23 879.57 1026.47 1123.89 831.13 887.57 1069.27 1042.57
Standard Deviation 93.56 118.19 159.74 144.65 96.69 115.55 124.79 131.03 98.32 117.19 149.27 146.47
Intensity Change Log 2 — 0.233530 0.569111 0.436197 — 0.072899 0.295720 0.426529 — 0.151670 0.432456 0.431144

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000310 0.000363 0.000203 0.002291 0.000332 0.001255 0.000416 0.000632 0.000331 0.000787 0.000328 0.002065
Bud Neck 0.012582 0.006358 0.001162 0.013997 0.004291 0.006698 0.008449 0.001684 0.004854 0.006520 0.005412 0.012323
Bud Site 0.018666 0.018871 0.008758 0.032377 0.005564 0.010767 0.010813 0.008675 0.006454 0.015017 0.009957 0.029156
Cell Periphery 0.000308 0.000099 0.000065 0.000167 0.000094 0.000128 0.000130 0.000117 0.000108 0.000113 0.000103 0.000160
Cytoplasm 0.533880 0.623365 0.763304 0.343226 0.645167 0.556097 0.524062 0.636692 0.637606 0.591373 0.623768 0.383115
Cytoplasmic Foci 0.252762 0.174283 0.014256 0.008718 0.126852 0.131712 0.008560 0.027989 0.135406 0.154037 0.010934 0.011337
Eisosomes 0.000149 0.000049 0.000007 0.000024 0.000047 0.000072 0.000018 0.000022 0.000054 0.000060 0.000013 0.000024
Endoplasmic Reticulum 0.000733 0.000817 0.000731 0.003227 0.001199 0.001022 0.002031 0.002340 0.001168 0.000915 0.001489 0.003107
Endosome 0.033789 0.018697 0.001256 0.005866 0.007309 0.018042 0.002272 0.015436 0.009108 0.018385 0.001848 0.007167
Golgi 0.005001 0.006061 0.000165 0.005940 0.002053 0.003708 0.002058 0.000523 0.002253 0.004942 0.001269 0.005203
Lipid Particles 0.007778 0.002646 0.000590 0.000581 0.002281 0.003684 0.000542 0.024421 0.002655 0.003140 0.000562 0.003822
Mitochondria 0.004445 0.001752 0.000164 0.005156 0.000606 0.003780 0.002167 0.001015 0.000867 0.002717 0.001332 0.004593
Mitotic Spindle 0.000134 0.008832 0.005910 0.101390 0.000258 0.007672 0.028257 0.001823 0.000250 0.008280 0.018944 0.087856
None 0.002883 0.001463 0.005078 0.012336 0.003942 0.001611 0.007898 0.007016 0.003870 0.001533 0.006722 0.011613
Nuclear Periphery 0.000511 0.000155 0.000377 0.001972 0.000274 0.000415 0.001367 0.001841 0.000290 0.000279 0.000954 0.001954
Nuclear Periphery Foci 0.000999 0.001137 0.002366 0.003403 0.000776 0.000505 0.001038 0.008641 0.000791 0.000836 0.001591 0.004115
Nucleolus 0.000801 0.000648 0.000107 0.000684 0.000564 0.000721 0.001084 0.000109 0.000580 0.000683 0.000677 0.000606
Nucleus 0.055127 0.048772 0.154757 0.402203 0.152241 0.103845 0.342205 0.121133 0.145644 0.074964 0.264084 0.363999
Peroxisomes 0.007898 0.004012 0.000096 0.000800 0.001007 0.002266 0.000506 0.000555 0.001475 0.003182 0.000335 0.000767
Vacuole 0.058353 0.080017 0.040515 0.050558 0.044284 0.143824 0.055530 0.138588 0.045240 0.110363 0.049272 0.062523
Vacuole Periphery 0.002888 0.001605 0.000135 0.005084 0.000859 0.002176 0.000598 0.000748 0.000997 0.001876 0.000405 0.004494

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.38 0.02 -4.73 -5.53 -5.98 -1.23 -0.79 -1.32 0.86 -1.42 -1.15 -0.47 -3.64 -1.26 -5.41
Bud Neck 1.91 3.42 -0.35 -4.69 -8.20 -3.53 -7.86 0.33 3.01 6.61 -2.88 -3.18 -5.65 -4.41 -4.31
Bud Site 0.08 2.25 0.87 1.66 -2.98 -3.65 -2.08 -2.36 0.33 -1.18 -6.48 -1.37 -4.25 0.54 -3.49
Cell Periphery 6.26 6.72 3.71 -8.91 -11.61 -2.59 -3.66 -3.61 -1.19 -2.02 -0.38 0.86 -8.51 -7.13 -9.78
Cytoplasm -3.24 -6.64 12.77 33.72 47.95 7.23 25.08 11.23 7.47 0.85 4.97 13.31 37.97 34.84 29.62
Cytoplasmic Foci 4.96 15.34 16.04 30.59 11.04 -0.53 28.77 20.56 19.47 -3.28 -2.98 30.40 31.06 39.09 4.72
Eisosomes 7.29 10.24 7.79 1.82 -18.00 -4.46 6.04 -0.43 3.91 -5.89 -1.33 10.89 3.05 5.20 -13.76
Endoplasmic Reticulum -0.98 -1.79 -8.01 -7.90 -7.68 0.91 -9.78 -2.86 -3.36 2.41 1.34 -6.80 -7.42 -8.10 -5.22
Endosome 2.80 5.96 5.86 11.26 -1.04 -7.51 8.20 2.34 7.25 -1.12 -7.39 9.95 8.10 15.66 -1.48
Golgi -0.48 3.75 2.62 3.80 -1.45 -1.55 2.75 5.61 3.56 1.45 -3.30 4.64 1.76 4.05 -0.88
Lipid Particles 1.98 2.81 2.57 1.49 -5.40 -1.72 7.19 -0.77 -0.25 -1.33 -0.77 7.07 1.78 1.91 -2.78
Mitochondria 1.16 1.82 0.89 -1.16 -7.30 -3.32 -2.79 1.57 3.56 3.39 -3.29 -0.50 -3.92 0.96 -3.41
Mitotic Spindle -3.95 -7.58 -9.03 -6.70 -7.46 -3.39 -11.66 -2.56 -0.12 5.30 -5.16 -13.16 -9.17 -6.94 -4.49
None 1.12 -1.26 -4.42 -12.38 -6.75 5.11 -7.27 -1.20 -3.49 2.02 6.01 -5.52 -7.30 -12.72 -4.17
Nuclear Periphery 0.94 -0.48 -6.68 -15.30 -12.71 -2.54 -21.13 -6.23 -5.50 3.74 0.01 -20.58 -15.31 -15.42 -6.60
Nuclear Periphery Foci -0.65 -6.63 -2.81 -2.54 1.77 2.32 -3.60 -3.89 -4.23 -3.41 -0.60 -9.61 -4.69 -4.40 -1.47
Nucleolus -0.06 2.92 -0.75 -0.47 -4.72 -1.08 -3.31 4.85 4.10 5.11 -0.83 -1.53 -1.73 -0.50 -0.47
Nucleus -0.08 -9.17 -27.85 -40.96 -29.26 5.98 -28.79 -1.70 -4.39 12.47 10.15 -22.70 -27.84 -37.24 -12.70
Peroxisomes 0.87 1.77 1.73 4.86 -3.66 -3.42 4.08 4.53 6.38 0.56 -3.07 3.78 3.57 6.74 -1.21
Vacuole -3.18 -2.75 -9.30 -9.01 -9.23 -16.04 -14.09 -13.90 -9.46 -11.23 -17.25 -14.82 -18.71 -9.06 -11.63
Vacuole Periphery 2.13 4.56 2.33 0.92 -1.78 -2.90 2.56 3.02 4.98 0.95 -2.88 3.74 0.13 1.83 -1.59
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes; relative distribution to nucleus increases upon DNA replication stress
Localization
Cell Percentages cytoplasm (84%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Msn2

Msn2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Msn2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available