Standard name
Human Ortholog
Description Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0 0 0
Cytoplasm 0.99 0.96 0.99 0.99 0.95 0.93 0.89 – 0.78 0.82 0.75 0.76 1.0 1.0 0.99 0.94 0.93 0.96 0.97 0.92 0.94 0.92 0.94 0.94
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.06 0.08 – 0.2 0.14 0.3 0.17 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0.05 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.05 0.05 0 – 0 0.05 0 0.05 0 0 0 0 0.07 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 – 0 1 1 0 0 0 0 0 0 0 0 3 0 0 1 1
Bud 0 1 0 0 0 2 0 – 1 4 2 2 0 0 0 0 0 0 0 2 1 1 2 6
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 4 3 3 0 5 3 – 6 2 3 4 0 2 3 7 9 7 0 0 0 0 0 0
Cytoplasm 200 301 224 226 269 273 363 – 193 240 188 191 335 478 473 134 191 147 190 293 212 117 324 377
Endoplasmic Reticulum 0 6 0 2 1 0 0 – 0 2 2 12 0 2 2 6 7 3 0 1 1 0 1 1
Endosome 0 0 0 0 1 0 0 – 0 1 1 0 0 0 0 1 2 0 0 2 1 1 1 2
Golgi 0 0 0 0 1 0 0 – 0 0 0 0 0 0 1 0 1 0 0 1 0 1 1 0
Mitochondria 0 2 0 2 3 19 33 – 49 42 76 42 0 0 0 3 3 2 2 2 2 1 4 1
Nucleus 2 2 1 0 1 4 9 – 5 11 9 12 1 2 0 7 3 2 0 1 0 0 1 0
Nuclear Periphery 0 1 0 0 0 0 0 – 2 2 3 1 0 0 0 0 2 0 0 0 0 0 0 0
Nucleolus 0 1 0 0 0 0 1 – 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0
SpindlePole 0 0 0 0 0 1 0 – 0 1 0 0 0 0 0 0 0 0 0 1 0 0 2 2
Vac/Vac Membrane 0 2 2 2 13 14 18 – 11 16 3 13 1 2 0 5 15 7 1 1 1 0 1 3
Unique Cell Count 202 313 226 229 283 295 407 246 294 250 252 336 480 477 143 206 153 196 318 227 128 347 403
Labelled Cell Count 202 320 231 235 289 318 427 269 322 288 277 338 486 479 164 233 168 196 318 227 128 347 403


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.8 6.6 7.0 6.4 7.3 6.0 6.2 – 5.6 5.8 5.1 5.5 6.7 7.0 6.8 8.3 8.4 8.2 6.3 7.0 7.5
Std Deviation (1e-4) 0.6 0.9 1.1 1.4 1.5 1.2 1.5 – 1.5 1.2 1.3 1.3 0.9 1.1 1.1 1.6 1.7 1.9 1.4 1.3 1.3
Intensity Change (Log2) – – – -0.13 0.06 -0.22 -0.17 – -0.33 -0.27 -0.44 -0.34 -0.07 0.01 -0.04 0.25 0.26 0.24 -0.15 0.0 0.1

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 1.9 0
Cytoplasm -0.4 -2.6 -3.5 -4.6 – -7.0 -6.4 -7.6 -7.5 0.9 0.8 0.1 -3.0 -3.4 -2.0
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 3.3 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 3.9 4.4 – 7.1 5.9 9.0 6.4 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 2.5 0 2.9 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 2.5 2.5 2.4 – 2.4 2.8 0 2.7 0 0 0 0 3.4 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0034 0.001 0.0013 0.0012 0.0079 0.0026 0.0205 0.0017 0.0025 0.0006 0.0062 0.0044 – – – – – –
Bud 0.0001 0.0307 0.0597 0.0003 0.0003 0.0035 0.0021 0.0129 0.0137 0.0001 0.0005 0.0001 – – – – – –
Bud Neck 0.0002 0.0001 0.0004 0.0004 0.0005 0.0023 0.0012 0.0003 0.0004 0.0003 0.0015 0.0012 – – – – – –
Bud Periphery 0.0001 0.0073 0.0206 0.0002 0.0002 0.0028 0.0021 0.005 0.009 0.0001 0.0005 0.0001 – – – – – –
Bud Site 0.0006 0.0234 0.0345 0.0001 0.0016 0.0001 0.0131 0.0134 0.005 0.0002 0.0005 0.0001 – – – – – –
Cell Periphery 0.0002 0.0006 0.0008 0.0001 0.0001 0.0004 0.0002 0.0002 0.0001 0 0.0001 0 – – – – – –
Cytoplasm 0.4542 0.6735 0.4483 0.572 0.4006 0.6742 0.0291 0.4384 0.403 0.2751 0.1418 0.5045 – – – – – –
Cytoplasmic Foci 0.0457 0.0028 0.0093 0.0074 0.0855 0.0138 0.1047 0.0096 0.0094 0.0084 0.0196 0.0176 – – – – – –
Eisosomes 0.0002 0.0001 0.0001 0.0001 0 0.0001 0.0002 0 0 0 0 0 – – – – – –
Endoplasmic Reticulum 0.0349 0.0028 0.0016 0.0011 0.0014 0.0023 0.0111 0.0026 0.0016 0.0083 0.0011 0.0017 – – – – – –
Endosome 0.0588 0.0003 0.0008 0.0016 0.0757 0.001 0.2573 0.0024 0.003 0.0164 0.0884 0.0199 – – – – – –
Golgi 0.0147 0.0001 0.0001 0.0022 0.1127 0.0001 0.0428 0.0005 0.003 0.0027 0.0632 0.0016 – – – – – –
Lipid Particles 0.031 0.0003 0.0002 0.0336 0.032 0.0002 0.0704 0.0007 0.0005 0.0095 0.004 0.001 – – – – – –
Mitochondria 0.0023 0.0005 0.0014 0.0039 0.0057 0.0003 0.0219 0.0007 0.0016 0.0256 0.0115 0.0011 – – – – – –
None 0.2805 0.2516 0.4071 0.3543 0.265 0.2847 0.2724 0.4936 0.4985 0.6282 0.6537 0.3989 – – – – – –
Nuclear Periphery 0.0286 0.0006 0.001 0.0012 0.0004 0.0012 0.032 0.0019 0.0023 0.0076 0.0007 0.0017 – – – – – –
Nucleolus 0.0006 0.0002 0.0007 0.0002 0.0001 0.0004 0.0023 0.0003 0.0006 0.0002 0.0001 0.0005 – – – – – –
Nucleus 0.0069 0.0023 0.0055 0.0018 0.0003 0.0043 0.0083 0.0084 0.0197 0.0086 0.0009 0.0217 – – – – – –
Peroxisomes 0.0262 0.0001 0.0002 0.0146 0.0073 0 0.0668 0.0026 0.0105 0.0021 0.0018 0.0022 – – – – – –
Punctate Nuclear 0.0068 0.0007 0.0052 0.0032 0.0007 0.0049 0.0257 0.004 0.0146 0.0034 0.0007 0.0204 – – – – – –
Vacuole 0.0028 0.0008 0.0011 0.0005 0.0012 0.0008 0.0107 0.0008 0.0007 0.0014 0.0019 0.001 – – – – – –
Vacuole Periphery 0.0013 0.0001 0.0002 0.0002 0.0008 0.0001 0.0052 0.0001 0.0001 0.0013 0.0013 0.0004 – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.696 8.244 5.7576 8.992 7.0335 6.5062 9.1936 8.9353 11.4876 9.6617
Translational Efficiency 0.3641 0.3754 0.5947 0.4316 0.404 0.6564 0.5057 0.6161 0.444 0.4873

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2231 152 1958 1461 66 2409 344 1835 2297 2561 2302 3296

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 714.30 717.25 777.32 763.35 766.90 770.41 1023.95 688.71 715.81 767.25 814.18 721.80
Standard Deviation 87.13 134.43 100.81 116.77 93.52 92.57 145.55 108.37 87.76 96.39 139.79 118.14
Intensity Change Log 2 — 0.005946 0.121979 0.095815 — 0.006588 0.417035 -0.155142 — 0.006278 0.282248 -0.028665

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000030 0.000373 0.000078 0.000082 0.000142 0.000352 0.000438 0.000208 0.000034 0.000354 0.000132 0.000152
Bud Neck 0.004617 0.005363 0.003516 0.001743 0.004225 0.008832 0.001792 0.006387 0.004605 0.008626 0.003259 0.004329
Bud Site 0.002264 0.019846 0.007572 0.002761 0.003324 0.007168 0.003255 0.012323 0.002294 0.007921 0.006927 0.008085
Cell Periphery 0.000079 0.000304 0.000090 0.000098 0.000320 0.000087 0.000198 0.000193 0.000086 0.000100 0.000106 0.000151
Cytoplasm 0.673004 0.530443 0.576254 0.612365 0.593924 0.677509 0.485399 0.566582 0.670732 0.668780 0.562677 0.586876
Cytoplasmic Foci 0.074660 0.101002 0.015060 0.019167 0.129180 0.070094 0.010330 0.027401 0.076227 0.071928 0.014353 0.023751
Eisosomes 0.000078 0.000092 0.000020 0.000024 0.000117 0.000053 0.000069 0.000038 0.000079 0.000056 0.000027 0.000032
Endoplasmic Reticulum 0.000179 0.001292 0.000721 0.001019 0.001374 0.000406 0.005511 0.001942 0.000214 0.000458 0.001437 0.001533
Endosome 0.002310 0.004582 0.001020 0.001776 0.005647 0.004951 0.002325 0.004303 0.002406 0.004929 0.001215 0.003183
Golgi 0.000191 0.000150 0.000054 0.000073 0.000188 0.001437 0.000084 0.000680 0.000191 0.001361 0.000059 0.000411
Lipid Particles 0.001351 0.002452 0.000490 0.000825 0.003816 0.001971 0.001566 0.001911 0.001422 0.002000 0.000651 0.001429
Mitochondria 0.000458 0.000244 0.000270 0.000224 0.000200 0.003815 0.000200 0.000743 0.000451 0.003603 0.000259 0.000513
Mitotic Spindle 0.000339 0.000341 0.002825 0.000819 0.000052 0.009030 0.000780 0.007610 0.000331 0.008515 0.002519 0.004600
None 0.005072 0.004265 0.007330 0.006571 0.002596 0.002292 0.008615 0.005883 0.005001 0.002409 0.007522 0.006188
Nuclear Periphery 0.000181 0.000564 0.000646 0.000609 0.000355 0.000364 0.001157 0.001298 0.000186 0.000376 0.000722 0.000993
Nuclear Periphery Foci 0.000340 0.001178 0.000430 0.000960 0.002126 0.000286 0.003591 0.001079 0.000391 0.000339 0.000902 0.001026
Nucleolus 0.000541 0.000816 0.000300 0.000382 0.000675 0.000522 0.000143 0.000754 0.000545 0.000540 0.000277 0.000589
Nucleus 0.189249 0.253126 0.355947 0.316431 0.162754 0.153172 0.263826 0.311569 0.188488 0.159104 0.342181 0.313724
Peroxisomes 0.000567 0.001037 0.000164 0.000362 0.000749 0.004911 0.000131 0.000940 0.000572 0.004682 0.000159 0.000684
Vacuole 0.044385 0.072317 0.027095 0.033494 0.088055 0.052063 0.210503 0.047717 0.045640 0.053265 0.054503 0.041412
Vacuole Periphery 0.000104 0.000213 0.000120 0.000217 0.000182 0.000685 0.000088 0.000438 0.000106 0.000657 0.000115 0.000340

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.62 -6.60 -5.59 1.25 -0.15 -1.89 -4.99 -1.68 1.05 4.38 -3.70 -10.54 -8.78 1.91 -1.44
Bud Neck -0.33 1.12 4.04 2.19 2.55 -2.78 0.57 -1.72 1.58 -3.83 -3.60 1.31 0.07 3.73 -1.31
Bud Site -1.87 -3.58 -0.81 1.80 3.17 -3.18 -2.25 -4.62 -2.55 -3.88 -5.29 -3.87 -5.27 0.05 -0.54
Cell Periphery -2.16 -1.90 -3.19 1.91 -0.83 3.30 2.00 1.79 -8.54 -0.92 -1.54 -2.69 -8.41 -5.21 -4.89
Cytoplasm 6.58 15.90 9.96 -2.97 -4.06 -2.76 9.32 1.30 16.62 -19.49 0.92 21.83 16.69 15.12 -6.95
Cytoplasmic Foci -2.28 25.29 21.67 7.42 -3.20 3.11 6.45 5.58 17.26 -9.46 1.37 26.55 21.99 20.84 -7.64
Eisosomes -1.41 10.70 9.58 6.39 -2.25 4.19 1.71 4.97 2.70 9.91 3.90 9.09 8.48 5.63 -1.48
Endoplasmic Reticulum -3.83 -13.52 -9.28 0.51 -2.33 2.30 -5.33 -1.77 -13.97 5.53 -3.79 -14.74 -18.87 -12.88 -2.44
Endosome -3.51 6.17 1.43 4.07 -3.08 0.56 3.75 1.58 1.64 -4.09 -5.51 6.03 -1.89 3.88 -6.75
Golgi 1.18 3.67 3.11 3.10 -1.65 -3.49 2.77 -0.99 1.56 -1.22 -3.45 3.62 -0.73 2.46 -1.33
Lipid Particles -2.67 7.37 2.57 3.57 -3.21 1.96 2.35 2.10 0.24 -1.39 -2.22 6.45 -0.56 1.98 -8.00
Mitochondria 2.02 1.57 2.06 0.12 1.38 -4.75 -0.02 -5.88 4.05 -7.00 -4.33 1.67 -0.29 4.33 -4.59
Mitotic Spindle 0.55 -2.85 -1.10 -1.78 2.27 -6.49 -3.84 -5.69 0.68 -4.41 -6.06 -3.05 -5.27 2.52 -2.19
None 0.87 -1.91 -1.29 -1.76 0.76 0.34 -1.99 -4.35 -6.80 -2.19 4.88 -1.70 -1.16 -8.07 0.93
Nuclear Periphery -5.58 -22.05 -19.49 -1.10 2.52 -0.42 -11.89 -14.20 -20.12 0.63 -9.47 -26.14 -29.31 -19.78 -6.06
Nuclear Periphery Foci -3.39 -3.09 -6.93 1.17 -5.40 2.79 -2.47 1.37 -9.36 7.84 0.26 -8.03 -9.65 -9.91 -1.85
Nucleolus -1.36 3.35 2.14 2.60 -1.79 0.36 2.42 -0.32 -1.36 -7.12 -0.23 3.83 -0.14 0.14 -5.67
Nucleus -2.62 -27.02 -18.99 -3.70 4.96 0.61 -2.35 -6.10 -23.59 -6.22 6.00 -25.57 -24.19 -29.24 4.03
Peroxisomes -1.28 4.90 0.25 1.08 -1.11 -4.60 4.54 -0.60 4.32 -3.35 -4.83 5.23 -0.67 4.56 -3.00
Vacuole -4.40 3.98 0.80 4.58 -2.59 2.00 -13.44 1.14 -4.82 21.80 -3.91 -11.07 -4.53 -0.88 8.26
Vacuole Periphery -3.37 -0.61 -1.72 -0.08 -1.43 -3.74 3.27 -2.69 1.94 -4.35 -4.44 -0.28 -4.14 2.58 -3.86
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant
Localization
Cell Percentages cytoplasm (68%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ypk2

Ypk2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ypk2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available