Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L15B; binds to 5.8 S rRNA; homologous to mammalian ribosomal protein L15, no bacterial homolog; RPL15B has a paralog, RPL15A, that arose from the whole genome duplication; relocalizes from nucleus to nucleolus upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.05 0 0.05 0.12 0.17 0.27 0.22 0.2 0.16 0.19 0.08 0.17 0.29 0.13 0.13 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0.05 0.15 0.27 0.05 0.26 0.09 0.07 0.14 0.11 0.14 0.16 0.24 0.31 0.12 0.09 0.06 0 0 0 0.11 0.18 0.2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.07 0 0.51 0.13 0.24 0.52 0.35 0.46 0.37 0 0 0 0.05 0.06 0.08 0 0 0 0 0 0
Nucleus 0.8 0.8 0.68 0.29 0.32 0.22 0.29 0.29 0.16 0.26 0.29 0.19 0.29 0.17 0.17 0.43 0.39 0.38 0.52 0.58 0.36 0.23 0.16 0.16
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.16 0.14 0.26 0.64 0.35 0.23 0.13 0.08 0.1 0.09 0.1 0.07 0.61 0.57 0.25 0.32 0.33 0.46 0.33 0.25 0.43 0.32 0.26 0.24
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0.07 0.41 0.32 0.12 0.2 0.14 0.08 0.15 0.09 0.16 0.19 0.26 0.34 0.11 0.09 0.1 0 0 0.06 0.11 0.14 0.17
Vac/Vac Membrane 0 0.09 0 0 0.09 0.05 0.12 0.1 0.16 0.12 0.08 0.15 0 0 0 0.07 0.12 0.08 0.06 0.09 0.05 0.15 0.15 0.14
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Bud 0 1 0 1 2 5 3 3 3 7 6 1 1 0 0 0 0 1 5 2 0 1 3 1
Bud Neck 0 0 0 3 2 0 0 2 1 1 0 0 0 2 0 0 0 0 0 0 0 1 1 2
Bud Site 0 0 0 1 0 8 3 5 5 3 4 4 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 4 6 8 7 8 17 28 66 36 42 35 46 22 57 102 42 35 19 2 0 0 1 2 3
Endoplasmic Reticulum 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 10 9 3 0 0 0 1 0 0
Endosome 2 3 8 37 48 7 42 22 11 28 24 35 43 80 109 39 24 16 6 10 8 25 54 62
Golgi 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 2 0 1 3 0
Mitochondria 9 11 0 16 2 70 21 60 86 72 103 89 5 3 2 18 16 19 0 7 3 5 7 7
Nucleus 235 318 111 71 56 30 48 71 27 54 64 47 78 56 58 144 101 96 178 259 68 53 48 51
Nuclear Periphery 8 6 3 1 0 1 1 0 1 0 0 1 0 3 0 2 2 1 6 2 4 3 5 7
Nucleolus 47 54 42 156 62 32 22 19 16 19 22 16 164 194 89 106 87 116 113 111 82 75 76 73
Peroxisomes 1 0 0 1 2 0 0 3 1 2 1 2 1 0 4 1 0 0 0 0 0 0 0 0
SpindlePole 0 4 11 100 56 16 32 34 13 32 21 40 51 89 120 37 24 26 4 5 11 26 42 52
Vac/Vac Membrane 13 34 4 4 15 7 20 26 26 24 19 36 4 9 14 25 31 20 22 39 8 36 44 43
Unique Cell Count 292 399 163 244 175 138 163 248 166 207 224 243 268 338 350 335 260 252 344 446 191 237 298 314
Labelled Cell Count 319 438 187 399 253 193 220 312 226 284 299 317 370 493 498 424 332 318 344 446 191 237 298 314


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.3 7.5 7.9 7.4 7.5 4.4 5.3 5.0 4.5 4.6 4.6 4.7 8.0 6.7 6.1 8.6 9.9 8.7 7.2 6.8 7.0
Std Deviation (1e-4) 1.4 1.4 1.4 1.4 5.1 1.7 1.7 1.5 1.4 1.3 1.0 1.2 1.9 1.5 1.7 2.0 2.0 2.2 1.4 1.5 2.1
Intensity Change (Log2) – – – -0.09 -0.08 -0.83 -0.57 -0.67 -0.82 -0.76 -0.78 -0.75 0.02 -0.25 -0.37 0.13 0.32 0.15 -0.13 -0.22 -0.17


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.1 -0.1 2.3 3.5 5.6 4.5 4.3 3.3 4.1 1.3 3.7 6.2 2.7 2.8 1.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 3.2 5.6 0 5.2 1.5 0 0 0 0 3.5 5.2 6.6 2.4 1.6 0.6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.3 0 0 4.7 6.8 0 0 0 0 0 0 0 3.0 3.2 3.6
Nucleus -7.8 -6.6 -8.0 -7.0 -7.9 -9.5 -8.1 -7.7 -9.9 -7.9 -11.5 -11.6 -5.3 -5.9 -6.0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 7.5 1.9 0 -2.8 -5.1 0 0 0 0 7.1 6.6 -0.1 1.3 1.7 4.2
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 7.6 5.8 0 3.4 2.2 0 0 0 0 3.5 5.1 6.7 1.5 0.9 1.2
Vacuole 0 2.4 1.2 3.4 3.1 4.2 3.3 2.5 4.1 0 0 0.9 2.2 3.4 2.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.7136 6.9055 6.3589 5.7118 6.0236 6.4152 5.3547 6.0961 5.5454 5.07 4.3647 5.8206 7.458 7.2939 6.6271 6.6585 6.6818 7.0299
Actin 0.0153 0 0.0268 0.0002 0.0271 0.0069 0.0665 0.0002 0.0048 0.0325 0.0021 0.0045 0.0263 0 0.0001 0.0103 0.0003 0.0131
Bud 0.0002 0.0001 0.0002 0.0005 0.0003 0.0001 0.0008 0.0002 0.0004 0.0004 0.0003 0.0001 0.0003 0.0001 0.0002 0.0003 0.0002 0.0001
Bud Neck 0.001 0.0014 0.0022 0.0019 0.0018 0.0017 0.0034 0.0017 0.0013 0.0029 0.0011 0.0024 0.0008 0.0015 0.0009 0.001 0.0008 0.0017
Bud Periphery 0.0005 0.0001 0.0004 0.0012 0.0007 0.0003 0.0019 0.0005 0.0014 0.001 0.0009 0.0005 0.0006 0.0002 0.0005 0.0005 0.0008 0.0003
Bud Site 0.0015 0.0006 0.0026 0.0009 0.0009 0.0003 0.0091 0.0013 0.002 0.0023 0.0012 0.0004 0.0009 0.001 0.001 0.0008 0.0004 0.0004
Cell Periphery 0.0003 0.0002 0.0003 0.0016 0.0002 0.0002 0.001 0.0005 0.0005 0.0007 0.0003 0.0002 0.0002 0.0002 0.0003 0.0001 0.0001 0.0001
Cytoplasm 0.0056 0.0003 0.0027 0.0243 0.0008 0.0002 0.0091 0.0007 0.0097 0.0007 0.0014 0.0004 0.0011 0.0034 0.0006 0.0009 0.0002 0.0001
Cytoplasmic Foci 0.0047 0.0002 0.0044 0.0007 0.0004 0.0004 0.0233 0.0003 0.01 0.001 0.0069 0.0009 0.0095 0.0004 0.0009 0.0045 0.0001 0.002
Eisosomes 0.0003 0 0.0005 0.0007 0.0003 0 0.0006 0 0.0001 0.0003 0.0001 0 0.0002 0 0 0.0001 0.0001 0
Endoplasmic Reticulum 0.0014 0 0.0005 0.0016 0.0011 0.0001 0.005 0.0003 0.0015 0.0023 0.0027 0.0023 0.0013 0.0003 0.0009 0.0013 0.0001 0.0001
Endosome 0.0079 0.0003 0.0045 0.002 0.0037 0.001 0.0294 0.0017 0.0109 0.0071 0.0168 0.0046 0.0157 0.0025 0.0086 0.0104 0.0005 0.0016
Golgi 0.0032 0 0.0028 0.0001 0.0026 0.0026 0.0216 0.0001 0.0091 0.005 0.0055 0.002 0.0052 0 0.0005 0.0096 0.0001 0.0013
Lipid Particles 0.0084 0.0004 0.0051 0.0014 0.0014 0.0007 0.0222 0.0008 0.0084 0.0025 0.029 0.0098 0.0083 0.0004 0.0034 0.0121 0.0005 0.0046
Mitochondria 0.018 0.0001 0.0016 0.0007 0.003 0.0055 0.0239 0.0012 0.0101 0.0044 0.0746 0.0009 0.0252 0.0002 0.0019 0.0046 0.0024 0.0008
None 0.001 0 0.0109 0.0407 0.0043 0.0001 0.0143 0.0069 0.004 0.0004 0.0011 0.0002 0.0008 0.0019 0.0003 0.0005 0.0006 0.0001
Nuclear Periphery 0.0149 0.0015 0.006 0.0055 0.0443 0.0044 0.0067 0.0052 0.0082 0.0039 0.0138 0.0126 0.0213 0.0124 0.0057 0.0112 0.0077 0.0024
Nucleolus 0.4679 0.4168 0.528 0.3834 0.3265 0.5396 0.413 0.5723 0.6327 0.5406 0.333 0.608 0.4347 0.5171 0.6332 0.5209 0.2453 0.5205
Nucleus 0.424 0.5676 0.3666 0.5081 0.5255 0.4116 0.2927 0.3887 0.2253 0.3434 0.4586 0.3291 0.394 0.4351 0.3069 0.3539 0.6949 0.4204
Peroxisomes 0.0028 0 0.0018 0.0001 0.0003 0.0005 0.024 0.0001 0.0137 0.0004 0.0016 0.0013 0.0052 0 0.0001 0.0018 0.0002 0.0027
Punctate Nuclear 0.0185 0.0085 0.0262 0.0027 0.0516 0.0223 0.0213 0.0075 0.0351 0.034 0.0397 0.0171 0.0453 0.014 0.0136 0.053 0.0429 0.0267
Vacuole 0.0013 0.0016 0.0045 0.0185 0.0014 0.001 0.0081 0.0083 0.0072 0.0132 0.0043 0.0014 0.0015 0.0085 0.016 0.0012 0.0008 0.0007
Vacuole Periphery 0.0013 0.0002 0.0013 0.0032 0.0018 0.0003 0.0021 0.0014 0.0035 0.001 0.0051 0.0012 0.0017 0.0005 0.0045 0.0008 0.001 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 610.0122 705.7 884.2711 637.1796 768.8086 749.541 597.9889 618.948 742.4403 567.4522
Translational Efficiency 1.5479 1.4603 1.1759 1.7911 1.4388 1.2602 1.4881 1.5594 1.2303 1.5247

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1623 569 2820 1697 1821 2958 2552 1033 3444 3527 5372 2730

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 800.25 986.83 1124.75 1206.52 761.17 947.68 1127.48 1015.23 779.59 954.00 1126.05 1134.14
Standard Deviation 118.99 155.93 173.06 370.61 113.32 142.32 183.68 221.63 117.65 145.32 178.19 335.51
Intensity Change Log 2 — 0.302351 0.491082 0.592329 — 0.316181 0.566811 0.415516 — 0.309110 0.528496 0.508838

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000284 0.000883 0.000472 0.000934 0.000273 0.000262 0.000575 0.001069 0.000278 0.000363 0.000521 0.000985
Bud Neck 0.004474 0.020222 0.028653 0.033928 0.004282 0.015369 0.022199 0.034746 0.004372 0.016152 0.025587 0.034237
Bud Site 0.000614 0.003800 0.001062 0.003590 0.000582 0.001588 0.000958 0.013238 0.000597 0.001945 0.001013 0.007240
Cell Periphery 0.000074 0.000152 0.000039 0.000134 0.000069 0.000121 0.000045 0.000362 0.000072 0.000126 0.000042 0.000220
Cytoplasm 0.004753 0.009184 0.000552 0.004405 0.008118 0.005568 0.000845 0.029547 0.006532 0.006152 0.000691 0.013919
Cytoplasmic Foci 0.001022 0.002561 0.000023 0.000573 0.002019 0.000397 0.000029 0.007782 0.001549 0.000747 0.000026 0.003301
Eisosomes 0.000029 0.000055 0.000028 0.000043 0.000031 0.000032 0.000036 0.000074 0.000030 0.000036 0.000032 0.000055
Endoplasmic Reticulum 0.003918 0.006351 0.002100 0.002527 0.001976 0.003499 0.002144 0.003061 0.002891 0.003959 0.002121 0.002729
Endosome 0.000823 0.003130 0.000281 0.001040 0.000943 0.001409 0.000317 0.014445 0.000886 0.001687 0.000298 0.006113
Golgi 0.000327 0.000785 0.000136 0.000675 0.000413 0.000205 0.000118 0.003782 0.000372 0.000299 0.000127 0.001851
Lipid Particles 0.000925 0.000805 0.000028 0.000117 0.000780 0.000290 0.000026 0.003627 0.000848 0.000373 0.000028 0.001445
Mitochondria 0.001749 0.002403 0.001461 0.005418 0.001395 0.003448 0.001315 0.008504 0.001562 0.003280 0.001392 0.006586
Mitotic Spindle 0.002810 0.014320 0.002004 0.018185 0.002560 0.004214 0.001512 0.044428 0.002678 0.005845 0.001770 0.028115
None 0.005478 0.008195 0.000671 0.002959 0.011295 0.006419 0.001135 0.017348 0.008554 0.006706 0.000891 0.008404
Nuclear Periphery 0.005519 0.004388 0.001684 0.012150 0.001708 0.002409 0.001095 0.004913 0.003504 0.002728 0.001404 0.009412
Nuclear Periphery Foci 0.004924 0.006897 0.000422 0.004252 0.003750 0.001140 0.000492 0.004633 0.004303 0.002069 0.000455 0.004396
Nucleolus 0.279401* 0.317252* 0.274444* 0.356826* 0.325594* 0.239259* 0.264533* 0.266792* 0.303825* 0.251841* 0.269736* 0.322758*
Nucleus 0.681244* 0.590294* 0.683953* 0.533720* 0.631877* 0.709746* 0.700977* 0.505287* 0.655141* 0.690475* 0.692040* 0.522961*
Peroxisomes 0.000635 0.001786 0.000406 0.001038 0.000913 0.000602 0.000566 0.003815 0.000782 0.000793 0.000482 0.002089
Vacuole 0.000607 0.005054 0.000896 0.008185 0.000988 0.002820 0.000516 0.024043 0.000809 0.003180 0.000715 0.014185
Vacuole Periphery 0.000390 0.001483 0.000685 0.009299 0.000433 0.001199 0.000566 0.008504 0.000413 0.001245 0.000628 0.008999

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.94 -10.25 -17.43 -0.11 -12.06 0.15 -4.16 -6.73 -8.46 -5.16 -1.94 -6.40 -12.61 -12.23 -10.70
Bud Neck -10.17 -24.01 -21.43 -8.10 -4.46 -15.11 -22.38 -18.28 -13.69 -9.20 -17.71 -32.82 -28.30 -18.70 -9.80
Bud Site -4.26 -2.94 -6.28 -0.31 -4.98 -4.21 -4.12 -9.68 -9.02 -9.32 -6.04 -4.54 -11.43 -9.16 -10.45
Cell Periphery -2.09 3.11 -2.79 0.41 -4.75 -2.69 3.51 -7.96 -5.33 -9.02 -3.13 4.48 -7.23 -3.14 -9.35
Cytoplasm -2.00 4.64 0.36 2.17 -4.06 2.26 6.85 -6.80 -8.02 -9.83 0.59 8.26 -4.91 -5.28 -10.39
Cytoplasmic Foci -1.83 3.88 1.09 2.29 -3.20 3.18 3.95 -3.22 -6.11 -6.66 2.42 5.22 -1.67 -4.43 -7.33
Eisosomes -7.51 1.08 -6.15 3.72 -7.51 0.36 -1.54 -10.64 -11.19 -10.41 -3.87 -0.21 -11.41 -8.43 -12.16
Endoplasmic Reticulum -4.33 8.01 4.03 6.00 -3.40 -6.00 -1.95 -7.89 -1.22 -7.11 -4.66 5.40 -1.90 3.12 -6.84
Endosome -3.33 3.82 -1.58 2.90 -5.91 -1.74 3.88 -5.94 -5.69 -6.41 -3.72 5.47 -6.04 -4.66 -7.15
Golgi -2.21 1.29 -1.73 0.80 -3.89 2.46 3.24 -4.07 -4.62 -4.76 0.96 3.02 -4.36 -5.04 -5.89
Lipid Particles 0.08 3.33 2.73 3.77 -5.83 4.08 6.92 -2.43 -3.30 -3.71 3.18 6.00 -0.56 -2.57 -4.09
Mitochondria -1.74 0.40 -8.28 -6.75 -10.12 -4.37 -0.38 -5.85 -3.34 -5.85 -4.27 0.05 -10.14 -5.09 -10.72
Mitotic Spindle -3.43 -0.14 -7.10 -1.43 -7.32 -1.28 0.17 -10.28 -9.98 -10.37 -2.97 -0.05 -12.36 -10.74 -12.55
None -0.95 6.30 2.71 2.16 -3.27 3.26 7.94 -0.87 -3.37 -6.42 1.84 10.01 1.62 -0.18 -7.08
Nuclear Periphery 0.89 4.03 -4.22 -5.01 -8.60 -1.55 1.36 -3.35 -2.67 -4.21 1.43 4.12 -6.14 -7.70 -9.64
Nuclear Periphery Foci -1.44 5.02 0.63 2.00 -5.55 4.60 5.50 0.54 -3.08 -3.84 4.03 7.38 0.66 -3.32 -6.74
Nucleolus -2.83 0.44 -6.50 -2.00 -7.42 10.94 8.19 7.69 -0.35 1.37 8.52 6.40 0.20 -7.42 -5.45
Nucleus 7.62 0.53 15.43 3.72 16.41 -9.84 -8.54 10.06 18.39 17.26 -5.58 -5.92 17.39 22.74 24.04
Peroxisomes -3.51 2.45 -4.08 2.53 -10.69 1.27 1.55 -3.48 -4.33 -4.49 -0.28 2.32 -4.09 -4.01 -6.32
Vacuole -4.44 -1.84 -8.00 -2.36 -7.50 -3.55 1.36 -9.79 -9.15 -9.93 -5.73 -0.39 -12.44 -10.25 -12.38
Vacuole Periphery -3.85 -3.44 -8.32 -6.91 -7.96 -4.62 -1.56 -5.75 -4.89 -5.62 -5.95 -3.49 -10.07 -8.73 -9.75
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L15B; binds to 5.8 S rRNA; homologous to mammalian ribosomal protein L15, no bacterial homolog; RPL15B has a paralog, RPL15A, that arose from the whole genome duplication; relocalizes from nucleus to nucleolus upon DNA replication stress
Localization
Cell Percentages nucleus (48%), nucleolus (16%), mixed (30%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Rpl15b

Rpl15b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl15b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available