Standard name
Human Ortholog
Description Histone acetyltransferase (HAT) catalytic subunit of the SAS complex; acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family; other members are Sas4p and Sas5p

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.08 0.11 0.27 0.24 0.42 0.42 0.38 0.38 0.29 0.37 0.23 0.32 0.41 0.43 0.16 0.14 0.08 0.06 0.08 0.12 0.18 0.22 0.22
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.56 0.06 0 0.11 0.14 0.42 0.56 0.45 0.67 0.58 0.74 0.55 0 0 0 0 0.08 0 0 0 0.06 0.05 0
Nucleus 0.6 0.62 0.62 0.63 0.29 0.23 0.25 0.29 0.25 0.23 0.26 0.24 0.46 0.41 0.68 0.7 0.67 0.61 0.61 0.49 0.34 0.22 0.14
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06
Vac/Vac Membrane 0.07 0.26 0.05 0 0.16 0.06 0.07 0 0.05 0 0.06 0.09 0.13 0.17 0.16 0.14 0.18 0.22 0.19 0.25 0.31 0.31 0.41
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2
Bud 0 0 0 1 0 2 5 8 11 5 10 6 0 0 0 0 0 4 2 2 0 3 8
Bud Neck 0 0 3 0 3 4 1 9 2 4 2 4 2 1 0 0 1 0 0 0 0 2 2
Bud Site 0 1 0 0 0 2 7 5 10 5 11 1 0 0 0 1 0
Cell Periphery 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0
Cytoplasm 34 14 46 49 149 136 151 178 136 185 100 114 68 77 35 30 11 25 12 30 14 36 39
Endoplasmic Reticulum 1 3 1 0 0 1 1 1 0 0 0 0 1 1 6 12 6 0 0 1 1 1 2
Endosome 0 2 1 5 20 3 1 1 0 2 0 2 5 6 8 8 5 6 0 2 1 2 1
Golgi 1 0 1 0 0 1 0 0 0 0 0 0 0 0 3 0 1 0 2 1 0 0 1
Mitochondria 226 7 5 22 51 136 221 212 320 290 326 196 1 3 6 9 10 7 5 9 4 8 5
Nucleus 241 77 105 126 103 75 99 135 121 113 115 85 75 74 146 150 88 264 91 123 27 36 26
Nuclear Periphery 1 0 0 0 0 1 0 0 2 1 0 0 0 0 0 3 0 0 1 0 0 1 1
Nucleolus 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 4 2 0 0 0 0 3 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
SpindlePole 0 0 1 6 6 2 3 7 5 7 3 5 0 1 3 1 2 15 1 7 1 9 10
Vac/Vac Membrane 28 33 9 6 56 21 26 18 24 16 27 31 21 30 34 29 23 96 29 62 25 51 73
Unique Cell Count 401 125 169 200 353 324 398 470 475 501 442 355 164 179 216 213 131 434 151 251 82 165 182
Labelled Cell Count 532 137 173 215 388 384 515 575 631 628 595 444 173 193 241 249 149 434 151 251 82 165 182


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.3 5.0 5.0 4.6 4.9 3.8 3.4 4.0 3.4 3.5 3.1 3.7 5.4 5.4 7.7 6.9 6.8 5.5 6.0
Std Deviation (1e-4) 0.4 1.2 1.1 1.3 1.7 1.4 1.2 1.0 1.4 0.8 0.9 1.2 1.9 1.9 1.7 1.7 1.7 2.1 2.2
Intensity Change (Log2) -0.13 -0.04 -0.4 -0.54 -0.33 -0.56 -0.51 -0.69 -0.42 0.1 0.1 0.62 0.47 0.45 0.12 0.26

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.6 3.3 3.2 2.5 2.5 0.4 2.3 -1.2 1.1 2.7 3.1 -2.6 -3.2 -4.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.7 0
Endosome 0 2.8 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 4.0 0 0 0 0 0 0 0 0 0 0 0.7 1.8
Nucleus 0.2 -7.2 -8.5 -8.5 -7.7 -8.6 -9.5 -8.3 -8.5 -3.0 -3.9 1.1 1.7 0.9
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -1.1 3.4 0.5 0.5 -0.8 -0.1 -1.3 0.4 1.4 2.4 3.4 3.2 2.7 3.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.7757 -0.1967 -0.4656 -0.5032 -0.6907 -0.3993 -0.0277 0.471 0.4125 0.2885 0.0378 0.4744 -0.4084 0.0548 -0.1115 0.1464 -0.3989 -0.2796
Actin 0.0004 0.0001 0.0001 0.0001 0.0001 0.0001 0.0018 0.0001 0 0 0.0001 0.0001 0.0056 0 0.0002 0.0005 0.0001 0.0017
Bud 0 0 0 0.0001 0 0 0.0001 0.0017 0 0 0 0 0.0001 0 0.0004 0 0 0.0001
Bud Neck 0.0004 0.0004 0.0002 0.0006 0.0004 0.0013 0.0008 0.0003 0.0002 0.0002 0.0005 0.0042 0.0018 0.0002 0.0011 0.0005 0.0005 0.0035
Bud Periphery 0 0 0 0.0001 0 0 0.0001 0.0002 0 0 0 0 0.0001 0 0.0014 0.0001 0 0
Bud Site 0.0002 0.0003 0 0.0002 0 0 0.0002 0.0007 0.0001 0 0 0.0001 0.0005 0.0001 0.0015 0.0001 0 0.0002
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0.0001 0 0 0 0 0
Cytoplasm 0.0377 0.0473 0.0146 0.0177 0.0253 0.0161 0.029 0.0348 0.0092 0.0135 0.0118 0.0176 0.0183 0.0242 0.0147 0.0153 0.0175 0.0118
Cytoplasmic Foci 0.0028 0.0013 0.0007 0.0007 0.0007 0.0005 0.0013 0.0006 0.0002 0.0001 0.0003 0.001 0.0023 0.0005 0.0014 0.0005 0.0003 0.001
Eisosomes 0.0001 0 0 0 0 0 0 0 0 0 0 0 0.0001 0 0 0.0001 0 0
Endoplasmic Reticulum 0.0014 0.0017 0.0003 0.0002 0.0004 0.0003 0.0012 0.0006 0.0002 0.0001 0.0001 0.0002 0.0008 0.0011 0.0003 0.0002 0.0002 0.0004
Endosome 0.0051 0.0023 0.0005 0.0003 0.0008 0.0004 0.0026 0.0005 0.0002 0.0002 0.0003 0.0007 0.0017 0.0007 0.0022 0.0006 0.0002 0.0009
Golgi 0.0002 0 0 0 0 0 0.0002 0 0 0 0 0 0.0007 0 0.0002 0.0007 0 0.0003
Lipid Particles 0.001 0.0002 0.0002 0 0.0001 0.0001 0.0003 0.0001 0.0001 0 0 0.0001 0.003 0.0001 0.002 0.0064 0 0.0025
Mitochondria 0.0005 0.0008 0.0002 0.0002 0.0003 0.0002 0.0005 0.0005 0.0003 0.0002 0.0003 0.0001 0.0005 0.0002 0.0009 0.025 0.0001 0.0001
None 0.1422 0.114 0.108 0.0915 0.0769 0.0985 0.0773 0.0783 0.0631 0.0602 0.091 0.0695 0.0489 0.0679 0.0394 0.0292 0.1219 0.0297
Nuclear Periphery 0.0194 0.0247 0.018 0.0116 0.02 0.0084 0.0148 0.0081 0.0085 0.0095 0.0072 0.0034 0.0143 0.0144 0.0118 0.0064 0.0095 0.0059
Nucleolus 0.0078 0.0079 0.0067 0.0074 0.0071 0.0127 0.0075 0.0052 0.006 0.0067 0.0104 0.0119 0.0093 0.0067 0.0074 0.0061 0.009 0.01
Nucleus 0.728 0.7609 0.8017 0.7822 0.8046 0.7853 0.8174 0.8441 0.8832 0.8678 0.8257 0.8397 0.8573 0.8531 0.8765 0.8818 0.8016 0.8786
Peroxisomes 0.0002 0.0001 0 0 0 0 0.0001 0 0 0 0 0 0.004 0 0.0016 0.0067 0 0.0007
Punctate Nuclear 0.0514 0.036 0.0483 0.0869 0.0626 0.0755 0.0438 0.0228 0.0285 0.0411 0.0519 0.0509 0.0296 0.0297 0.0363 0.0195 0.0388 0.0522
Vacuole 0.0008 0.0014 0.0002 0.0001 0.0003 0.0002 0.0006 0.001 0.0002 0.0001 0.0002 0.0003 0.0008 0.0007 0.0005 0.0002 0.0001 0.0002
Vacuole Periphery 0.0003 0.0004 0.0001 0.0001 0.0002 0.0001 0.0002 0.0002 0.0002 0.0001 0.0001 0 0.0002 0.0002 0.0002 0.0002 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 15.7319 9.6989 9.3561 9.1138 15.4737 13.0123 8.3355 5.6259 8.4646 14.8242
Translational Efficiency 0.5426 0.7738 0.4615 0.4488 0.441 0.703 0.4384 0.5745 0.4469 0.4482

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1474 1084 3140 1255 2330 2022 1751 1302 3804 3106 4891 2557

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 588.21 756.22 797.07 765.42 676.58 752.60 817.18 863.62 642.34 753.86 804.27 815.42
Standard Deviation 65.64 94.36 97.79 114.85 78.23 91.07 102.37 328.39 85.27 92.25 99.92 252.58
Intensity Change Log 2 0.362475 0.438375 0.379920 0.153623 0.272393 0.352136 0.254523 0.351966 0.365124

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000049 0.000300 0.000185 0.001644 0.000255 0.000199 0.000106 0.000469 0.000175 0.000235 0.000157 0.001046
Bud Neck 0.007855 0.007507 0.013260 0.011369 0.002519 0.007805 0.003020 0.010901 0.004586 0.007701 0.009594 0.011131
Bud Site 0.001971 0.003356 0.004376 0.012955 0.001038 0.003265 0.000812 0.012369 0.001399 0.003297 0.003100 0.012657
Cell Periphery 0.000301 0.000153 0.000117 0.000177 0.000107 0.000195 0.000584 0.000480 0.000182 0.000181 0.000284 0.000331
Cytoplasm 0.226211 0.108776 0.031442 0.069727 0.180481 0.105225 0.057574 0.074914 0.198201 0.106465 0.040797 0.072368
Cytoplasmic Foci 0.080500 0.026091 0.000212 0.002129 0.012409 0.015829 0.002944 0.003505 0.038794 0.019410 0.001190 0.002830
Eisosomes 0.000075 0.000043 0.000012 0.000028 0.000016 0.000029 0.000186 0.000024 0.000039 0.000034 0.000074 0.000026
Endoplasmic Reticulum 0.000942 0.003571 0.003030 0.006245 0.000697 0.001818 0.002029 0.005370 0.000792 0.002430 0.002672 0.005799
Endosome 0.002104 0.002440 0.000513 0.001453 0.000488 0.002030 0.000619 0.004479 0.001114 0.002173 0.000551 0.002994
Golgi 0.000758 0.000666 0.000043 0.001074 0.000161 0.000796 0.000452 0.002591 0.000392 0.000750 0.000190 0.001847
Lipid Particles 0.008684 0.003345 0.000205 0.000716 0.000950 0.001927 0.000960 0.001074 0.003947 0.002422 0.000475 0.000898
Mitochondria 0.007853 0.004955 0.001661 0.004632 0.000944 0.004978 0.000666 0.005627 0.003621 0.004970 0.001305 0.005139
Mitotic Spindle 0.000987 0.002053 0.002546 0.009924 0.000769 0.007485 0.000258 0.020060 0.000854 0.005589 0.001727 0.015085
None 0.024693 0.007881 0.002318 0.005404 0.006108 0.007357 0.017416 0.005112 0.013309 0.007540 0.007723 0.005256
Nuclear Periphery 0.000887 0.001611 0.001928 0.001585 0.000849 0.001343 0.000743 0.002085 0.000864 0.001436 0.001504 0.001840
Nuclear Periphery Foci 0.000330 0.000749 0.000116 0.000482 0.000111 0.000379 0.000084 0.000920 0.000196 0.000508 0.000104 0.000705
Nucleolus 0.004798 0.004782 0.000948 0.000921 0.001242 0.002382 0.000829 0.000812 0.002620 0.003219 0.000905 0.000866
Nucleus 0.621400 0.808259 0.932195 0.852563 0.787467 0.827818 0.906953 0.828038 0.723118 0.820992 0.923158 0.840075
Peroxisomes 0.004463 0.006132 0.000104 0.000617 0.000890 0.002937 0.000327 0.000481 0.002275 0.004052 0.000184 0.000547
Vacuole 0.004577 0.006580 0.004481 0.015487 0.002388 0.005391 0.003228 0.017786 0.003236 0.005806 0.004033 0.016657
Vacuole Periphery 0.000561 0.000751 0.000308 0.000869 0.000112 0.000812 0.000209 0.002902 0.000286 0.000791 0.000273 0.001904

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.23 -8.80 -2.68 -2.08 -2.34 0.25 0.61 -1.62 -6.33 -10.98 -0.64 -0.09 -2.91 -2.89 -3.19
Bud Neck 0.11 -4.49 -2.74 -2.86 0.74 -5.31 -1.45 -9.15 -3.29 -7.95 -3.86 -7.09 -7.84 -4.22 -1.94
Bud Site -1.65 -3.23 -4.87 -3.91 -3.51 -3.93 0.46 -6.11 -4.31 -6.36 -4.01 -3.60 -7.63 -5.76 -5.94
Cell Periphery 4.96 6.65 4.53 -0.16 -2.47 -1.63 -5.05 -2.07 -0.98 1.83 -0.00 -2.31 -0.99 -0.84 0.50
Cytoplasm 14.82 31.80 23.53 7.30 -8.62 13.24 24.15 18.99 6.59 -3.53 19.74 41.56 29.80 9.97 -9.42
Cytoplasmic Foci 12.22 21.75 21.18 10.07 -3.89 -2.27 10.27 10.12 10.49 0.69 9.48 23.21 22.28 14.62 -2.87
Eisosomes 6.82 18.57 10.06 2.51 -10.06 -4.75 -3.29 -10.82 -2.22 2.84 1.77 -1.70 1.74 -0.39 1.92
Endoplasmic Reticulum -8.75 -13.88 -18.56 -9.15 -11.60 -6.60 -8.59 -18.39 -15.20 -12.03 -10.86 -15.82 -25.96 -18.14 -16.27
Endosome -0.66 3.91 1.79 2.34 -3.13 -4.00 -0.56 -3.72 -0.70 -3.43 -3.22 3.10 -2.33 0.74 -4.48
Golgi 0.23 5.90 0.21 0.07 -1.90 -2.20 -0.86 -1.65 -0.54 -1.18 -1.86 2.06 -1.51 -0.39 -2.11
Lipid Particles 6.46 11.97 10.97 6.94 -3.96 -4.69 0.21 0.51 4.16 0.01 4.11 10.49 10.15 7.81 -1.82
Mitochondria 1.96 5.63 2.83 0.96 -1.68 -5.64 1.00 -3.95 1.33 -4.40 -1.96 4.95 -0.06 1.61 -3.58
Mitotic Spindle -1.67 -2.36 -4.12 -3.47 -3.14 -4.61 0.04 -6.00 -2.90 -5.99 -4.87 -2.31 -7.28 -3.76 -6.39
None 8.30 12.54 10.82 3.14 -4.46 -1.16 -4.82 1.44 2.33 5.48 5.50 5.89 9.77 3.65 2.95
Nuclear Periphery -4.46 -9.64 -11.89 -3.93 -0.60 -4.37 -0.86 -14.12 -9.59 -13.76 -6.18 -9.81 -18.49 -10.20 -7.69
Nuclear Periphery Foci -2.47 4.13 -2.55 0.82 -4.52 -3.79 0.14 -3.88 -1.97 -3.90 -4.18 2.83 -4.89 -1.22 -5.63
Nucleolus 0.08 7.56 7.79 6.52 0.34 -3.75 2.06 1.27 5.40 -1.08 -1.75 6.90 7.09 8.43 -0.08
Nucleus -16.33 -35.77 -21.73 -4.09 11.84 -5.24 -18.85 -3.89 0.62 11.04 -14.98 -38.91 -16.77 -2.20 16.86
Peroxisomes -1.42 8.32 6.92 5.15 -1.99 -4.09 2.18 2.45 6.36 0.07 -3.36 7.99 6.68 7.75 -1.84
Vacuole -3.88 -2.16 -10.73 -9.53 -9.93 -5.78 -3.18 -13.58 -12.32 -12.77 -6.74 -4.69 -17.39 -15.61 -15.97
Vacuole Periphery -0.87 2.02 -0.15 0.47 -1.17 -2.23 -0.75 -1.88 -0.77 -1.74 -2.31 0.40 -1.94 -0.49 -2.00
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Histone acetyltransferase (HAT) catalytic subunit of the SAS complex; acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family; other members are Sas4p and Sas5p
Localization
Cell Percentages nucleus (51%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Sas2

Sas2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sas2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available