Standard name
Human Ortholog
Description Mitochondrial external NADH dehydrogenase; type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain; NDE1 has a paralog, NDE2, that arose from the whole genome duplication
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.05 0.06 0.06 0 0 0 – 0 0 0 0 – 0 0 0.11 0.09 0.08 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0.05 – 0.07 0 0 0 – 0 0 0.07 0.08 0.15 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0.07 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0.05 0.06 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0.08 0.07 0
Golgi 0 0.13 0.41 0.25 0.33 0.06 0 – 0 0 0 0 – 0.49 0.45 0.62 0.51 0.41 0 0.12 0 0 0.09 0.13
Mitochondria 0.92 0.8 0.62 0.89 0.67 0.76 0.75 – 0.81 0.81 0.89 0.88 – 0.67 0.7 0.09 0.05 0.06 0.85 0.75 0.87 0.79 0.62 0.58
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.06 0 0 0 0 0.08 0.06 – 0.07 0.07 0.07 0.08 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0 0 0.06 – 0.05 0.07 0.07 0.05 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0.05 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.19 0.25 0.29 0.1 0.23 0.17 0.12 – 0.1 0.09 0.08 0.08 – 0.2 0.16 0.33 0.24 0.25 0 0 0 0 0.08 0.14
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 1 1 5 4 0 1 – 1 0 0 0 – 2 2 1 1 4 2 2 2 0 3 0
Bud 3 2 1 3 2 5 8 – 10 5 5 10 – 0 0 0 3 0 0 1 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 0
Bud Site 0 0 0 0 0 0 1 – 2 0 1 2 – 0 0 0 0 1 – – – – – –
Cell Periphery 4 10 9 18 7 9 4 – 3 5 7 5 – 4 3 5 9 9 0 0 0 0 0 0
Cytoplasm 3 4 3 9 8 9 25 – 22 11 16 12 – 2 3 3 8 16 1 3 0 0 0 0
Endoplasmic Reticulum 2 2 1 1 1 1 6 – 1 1 3 2 – 0 1 3 3 4 0 2 0 0 1 1
Endosome 0 2 3 4 7 21 29 – 12 11 3 5 – 0 2 0 1 1 7 3 4 1 4 1
Golgi 4 27 60 69 85 23 22 – 5 8 8 9 – 50 74 28 53 45 9 26 3 0 5 6
Mitochondria 264 164 91 250 174 305 369 – 263 277 426 365 – 68 115 4 5 7 245 170 150 13 39 29
Nucleus 2 2 2 0 4 5 5 – 3 7 4 6 – 0 0 0 1 1 0 0 0 0 0 0
Nuclear Periphery 18 1 2 2 4 31 29 – 23 23 32 35 – 2 1 0 2 2 0 1 0 0 0 0
Nucleolus 14 3 2 2 10 18 30 – 17 24 33 21 – 0 3 1 4 2 2 1 0 0 0 0
Peroxisomes 1 4 2 3 1 1 9 – 3 0 1 3 – 2 1 0 2 6 9 2 3 0 0 0
SpindlePole 1 1 4 0 1 3 9 – 1 8 3 4 – 0 0 1 0 1 1 0 0 0 0 0
Vac/Vac Membrane 53 52 43 27 59 67 60 – 33 31 36 33 – 20 26 15 25 27 5 8 3 0 5 7
Unique Cell Count 286 204 146 280 258 400 492 325 340 479 417 102 164 45 103 110 290 226 173 17 63 50
Labelled Cell Count 370 275 224 393 367 498 607 399 411 578 512 150 231 61 117 126 290 226 173 17 63 50


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.2 11.5 9.7 9.8 10.3 8.1 7.9 – 6.9 7.4 7.4 7.6 – 14.3 12.4 12.6 11.1 11.0 – 13.9 –
Std Deviation (1e-4) 1.3 4.1 1.6 1.8 2.5 1.9 2.6 – 1.8 2.0 2.0 1.9 – 3.3 2.7 4.2 2.8 3.3 – 6.3 –
Intensity Change (Log2) – – – 0.02 0.08 -0.26 -0.3 – -0.5 -0.39 -0.4 -0.35 – 0.55 0.35 0.38 0.19 0.18 – 0.52 –

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP70005101520WT3HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF14005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Cell Periphery 0.1 -1.7 0 0 – 0 0 0 0 – -0.8 -2.0 0 0.8 0.6
Cytoplasm 0 0 0 1.6 – 2.1 0 0 0 – 0 0 0 0 3.8
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Endosome 0 0 1.6 1.9 – 0 0 0 0 – 0 0 0 0 0
Golgi -3.5 -1.6 -10.2 -11.6 – -11.5 -11.3 -13.4 -12.3 – 1.2 0.7 2.5 1.6 0
Mitochondria 6.6 1.0 3.2 3.0 – 4.3 4.5 7.4 6.7 – 0.7 1.5 -6.3 -9.2 -9.1
Nucleus 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Nuclear Periphery 0 0 2.8 2.2 – 2.6 2.5 2.5 2.9 – 0 0 0 0 0
Nucleolus 0 0 1.7 2.3 – 2.0 2.6 2.5 1.9 – 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Vacuole -5.2 -1.5 -3.3 -5.0 – -5.3 -5.7 -7.0 -6.6 – -1.8 -2.9 0.5 -0.9 -0.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 23.6652 21.4915 21.9706 19.7251 18.2644 22.111 22.8501 24.312 22.2515 17.9587 21.2192 22.1901 21.1986 19.4219 22.7589 20.012 17.4753 18.2201
Actin 0.0013 0.0009 0.0007 0 0.0001 0.0013 0.0102 0.001 0.0092 0.0268 0.0021 0.0003 0.0354 0.0048 0.0182 0.0046 0.0003 0.0008
Bud 0 0.0001 0.0001 0 0 0.0001 0.0002 0.0001 0.0008 0.0016 0 0.0001 0.0005 0.0009 0.0003 0.0002 0.0001 0
Bud Neck 0 0 0 0 0 0 0.0002 0 0.0008 0.0008 0 0 0.0004 0.0005 0 0.0004 0.0001 0
Bud Periphery 0.0001 0.0001 0.0001 0 0.0001 0.0002 0.0004 0.0002 0.0017 0.0019 0.0001 0.0002 0.0007 0.0012 0.001 0.0005 0.0002 0
Bud Site 0.0001 0.0001 0.0003 0 0 0.0001 0.0008 0.0002 0.0034 0.0058 0.0002 0.0001 0.0028 0.0183 0.0008 0.0009 0.0001 0.0001
Cell Periphery 0.0002 0.0004 0.0003 0.0001 0.0004 0.0001 0.0003 0.0004 0.0005 0.0011 0.0001 0.0001 0.0003 0.0021 0.0001 0.0001 0.0002 0.0001
Cytoplasm 0 0 0.0001 0 0 0 0.0007 0 0.0008 0.0024 0.0006 0 0.0006 0 0 0 0.0001 0
Cytoplasmic Foci 0.0008 0.0004 0.0058 0 0.0001 0.0002 0.0131 0.0003 0.0021 0.0349 0.0077 0.0001 0.0124 0.0004 0.0003 0.0038 0.0015 0.0004
Eisosomes 0.0002 0.0003 0.0002 0.0001 0.0002 0.0001 0.0004 0.001 0.0005 0.0017 0.0003 0.0001 0.0003 0.0003 0.0008 0.0002 0.0001 0.0001
Endoplasmic Reticulum 0 0 0.0002 0 0 0 0.0011 0 0.0009 0.0022 0.0002 0 0.0004 0 0.0002 0.0001 0.0003 0
Endosome 0.0007 0.0013 0.0016 0.0002 0.0033 0.0011 0.0052 0.002 0.0059 0.0355 0.0081 0.0002 0.0083 0.0014 0.0009 0.0043 0.0392 0.0004
Golgi 0.0041 0.0034 0.001 0.0011 0.005 0.0046 0.0044 0.0068 0.0096 0.0258 0.0016 0.0004 0.01 0.0026 0.002 0.0071 0.0245 0.0011
Lipid Particles 0.0045 0.0041 0.0051 0.0005 0.0007 0.002 0.0173 0.004 0.0063 0.0144 0.0113 0.0006 0.0548 0.0063 0.0029 0.0431 0.0186 0.0048
Mitochondria 0.9763 0.9766 0.9578 0.994 0.9774 0.9761 0.9145 0.9559 0.9301 0.7961 0.9425 0.9919 0.8221 0.9102 0.9677 0.9114 0.8411 0.9864
None 0.0001 0 0.0007 0 0 0 0.0007 0 0.0021 0.004 0.0013 0 0.0031 0 0.0002 0.0001 0.0001 0
Nuclear Periphery 0 0 0.0004 0 0 0.0001 0.0049 0.0001 0.0029 0.0016 0.0025 0 0.0009 0.0001 0.0007 0.0001 0.0006 0
Nucleolus 0.0024 0.0002 0.0018 0 0 0 0.0015 0.0002 0.0014 0.0016 0.0005 0.0001 0.0045 0.0016 0.0001 0.0008 0.0004 0.0001
Nucleus 0.0003 0.0001 0.0007 0 0 0 0.0005 0.0001 0.0017 0.0006 0.0005 0 0.0006 0.0005 0.0001 0.0003 0.0003 0
Peroxisomes 0.0013 0.0022 0.0027 0.0001 0.0001 0.0004 0.0067 0.0016 0.0085 0.0322 0.0072 0.001 0.0211 0.0025 0.0012 0.0176 0.0008 0.0034
Punctate Nuclear 0.0001 0 0.0009 0 0 0 0.0004 0 0.0006 0.0037 0.0115 0 0.0028 0 0.0001 0.0004 0 0
Vacuole 0.0014 0.0015 0.0044 0.0003 0.0019 0.0009 0.0022 0.0042 0.0038 0.0021 0.0003 0.0009 0.003 0.0246 0.0003 0.0012 0.0163 0.0003
Vacuole Periphery 0.0062 0.008 0.0152 0.0035 0.0104 0.0125 0.0145 0.0219 0.0062 0.0031 0.0014 0.0042 0.015 0.0216 0.0018 0.0029 0.055 0.002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 55.0719 98.4618 101.7662 110.3813 76.5033 71.4228 110.9619 114.5875 115.452 92.159
Translational Efficiency 0.9675 1.1278 1.2491 1.3073 1.041 0.8644 1.1044 1.1691 1.0577 1.034

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1072 1209 836 566 1774 1753 207 623 2846 2962 1043 1189

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 627.25 926.30 1261.41 1393.68 759.37 939.21 1264.65 1450.73 709.60 933.94 1262.05 1423.57
Standard Deviation 157.16 164.72 203.79 301.19 106.96 164.25 202.72 282.36 143.29 164.56 203.58 292.86
Intensity Change Log 2 — 0.562439 1.007925 1.151787 — 0.306645 0.735863 0.933904 — 0.427998 0.865316 1.036557

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001448 0.001665 0.001871 0.006151 0.000671 0.001193 0.004200 0.003651 0.000964 0.001386 0.002333 0.004841
Bud Neck 0.016229 0.001389 0.006650 0.004866 0.004485 0.001059 0.005665 0.003288 0.008909 0.001193 0.006455 0.004039
Bud Site 0.015129 0.004903 0.011699 0.022258 0.011056 0.003634 0.027527 0.012206 0.012590 0.004152 0.014840 0.016991
Cell Periphery 0.001417 0.000416 0.000214 0.001141 0.000512 0.000471 0.000479 0.001118 0.000853 0.000449 0.000267 0.001129
Cytoplasm 0.012796 0.000695 0.001031 0.003150 0.004566 0.001979 0.001802 0.001153 0.007666 0.001455 0.001184 0.002104
Cytoplasmic Foci 0.053436 0.013126 0.033417 0.010911 0.037366 0.011468 0.059966 0.010278 0.043419 0.012145 0.038686 0.010579
Eisosomes 0.000149 0.000054 0.000069 0.000243 0.000060 0.000050 0.000078 0.000205 0.000094 0.000051 0.000071 0.000223
Endoplasmic Reticulum 0.001467 0.000328 0.000442 0.001313 0.000578 0.000303 0.001493 0.000885 0.000913 0.000313 0.000651 0.001088
Endosome 0.048972 0.028520 0.027195 0.018176 0.063991 0.020135 0.064303 0.011749 0.058334 0.023557 0.034559 0.014809
Golgi 0.054457 0.022952 0.052945 0.065826 0.103122 0.022963 0.115835 0.058156 0.084792 0.022958 0.065427 0.061807
Lipid Particles 0.016590 0.001741 0.002723 0.001667 0.001407 0.001929 0.002183 0.002816 0.007126 0.001852 0.002616 0.002269
Mitochondria 0.681615 0.881578 0.744277 0.760613 0.694692 0.901934 0.575779 0.772116 0.689766 0.893625 0.710836 0.766640
Mitotic Spindle 0.007159 0.003293 0.024848 0.013489 0.012663 0.002410 0.044480 0.006035 0.010590 0.002771 0.028744 0.009583
None 0.003409 0.000332 0.000956 0.001721 0.000620 0.000398 0.000558 0.002568 0.001670 0.000371 0.000877 0.002165
Nuclear Periphery 0.000501 0.000088 0.001928 0.001033 0.000123 0.000195 0.001228 0.001910 0.000265 0.000152 0.001789 0.001492
Nuclear Periphery Foci 0.000852 0.000208 0.001456 0.000913 0.000398 0.000221 0.001186 0.000967 0.000569 0.000216 0.001402 0.000941
Nucleolus 0.001805 0.000848 0.001021 0.000554 0.001059 0.000158 0.000310 0.002505 0.001340 0.000440 0.000880 0.001576
Nucleus 0.009142 0.000468 0.000443 0.000369 0.001423 0.000451 0.001692 0.001007 0.004330 0.000458 0.000691 0.000703
Peroxisomes 0.040977 0.016981 0.014071 0.005578 0.020362 0.008222 0.013494 0.003329 0.028127 0.011797 0.013956 0.004400
Vacuole 0.014899 0.010162 0.028135 0.032680 0.016379 0.008723 0.036757 0.035100 0.015822 0.009311 0.029846 0.033948
Vacuole Periphery 0.017550 0.010253 0.044609 0.047347 0.024468 0.012103 0.040984 0.068959 0.021862 0.011348 0.043890 0.058671

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.54 -1.35 -2.99 -2.82 -2.72 -1.80 -3.86 -2.44 -1.97 0.36 -1.79 -4.97 -3.94 -3.45 -2.49
Bud Neck 6.73 3.95 4.67 -3.42 1.33 4.40 -0.80 1.11 -3.20 1.60 7.97 1.88 4.24 -4.70 2.46
Bud Site 5.00 1.19 -1.63 -4.07 -2.28 6.11 -2.26 -0.53 -3.01 1.90 7.78 -1.04 -1.79 -5.10 -0.71
Cell Periphery 3.68 4.57 0.71 -2.45 -3.21 0.22 0.21 -1.59 -1.65 -1.69 2.68 4.75 -1.05 -2.70 -3.65
Cytoplasm 8.40 8.13 5.26 -2.15 -1.84 2.54 3.50 2.82 0.37 0.23 7.56 8.97 5.45 -1.13 -1.69
Cytoplasmic Foci 11.35 4.63 11.71 1.16 7.12 12.89 -2.74 12.62 0.63 6.05 17.05 1.51 17.23 1.16 9.47
Eisosomes 8.99 7.16 -2.49 -5.13 -4.68 1.85 -1.85 -4.61 -4.91 -3.88 7.82 3.63 -5.33 -7.11 -6.23
Endoplasmic Reticulum 4.46 3.96 0.40 -3.67 -3.21 3.04 -1.59 -1.35 -2.60 1.07 5.39 1.42 -0.89 -4.46 -1.93
Endosome 5.38 5.69 7.99 3.15 2.75 13.95 -0.03 16.07 3.57 7.21 14.27 7.59 17.28 4.46 7.14
Golgi 7.84 0.27 -1.52 -6.16 -1.64 18.53 -0.92 6.62 -6.10 4.09 19.81 3.78 4.48 -8.67 0.60
Lipid Particles 7.64 7.08 7.74 0.14 2.07 -1.13 -1.53 -1.69 -0.97 -0.67 6.63 5.47 5.62 -0.79 0.60
Mitochondria -16.35 -4.10 -4.59 7.90 -0.93 -22.35 4.43 -5.19 9.80 -6.83 -27.54 -1.67 -6.83 12.66 -3.95
Mitotic Spindle 3.04 -5.66 -2.10 -3.48 2.70 7.67 -3.52 3.46 -2.45 4.22 8.13 -5.92 0.45 -4.27 5.67
None 3.79 3.03 2.08 -11.42 -6.00 1.04 0.32 -6.58 -10.15 -9.40 3.89 2.40 -1.33 -14.07 -10.02
Nuclear Periphery 2.75 -3.87 -2.30 -5.43 2.39 -1.11 -3.86 -3.62 -3.47 -1.19 1.66 -5.38 -4.42 -4.92 0.81
Nuclear Periphery Foci 1.70 -1.31 -0.09 -3.86 1.81 1.08 -2.40 -1.99 -3.25 0.63 2.01 -2.96 -1.55 -4.91 1.86
Nucleolus 1.40 1.28 2.38 0.53 1.30 2.45 1.92 -1.02 -1.77 -1.64 2.57 1.09 -0.28 -1.55 -0.86
Nucleus 4.66 4.70 4.74 0.38 0.46 1.94 -0.37 0.44 -0.99 0.53 5.04 4.36 4.46 -0.79 0.02
Peroxisomes 5.99 6.93 9.46 4.18 3.43 5.81 1.88 9.35 3.26 3.00 8.10 6.04 12.74 5.04 5.13
Vacuole 2.22 -4.69 -4.24 -5.56 -0.97 6.00 -4.19 -5.05 -7.19 0.33 5.74 -6.27 -6.56 -9.08 -1.16
Vacuole Periphery 4.04 -7.18 -6.19 -7.77 -0.47 6.98 -2.99 -7.66 -9.92 -3.61 8.12 -6.93 -9.61 -12.52 -3.10
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial external NADH dehydrogenase; type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain; NDE1 has a paralog, NDE2, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (94%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Nde1

Nde1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nde1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available