ORF
Human Ortholog
Description Putative S-adenosylmethionine-dependent methyltransferase; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively; YMR209C is not an essential gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.13 0 0.06 0.07 0.08 0.11 0 0.06 0.06
Bud 0 0 0 0 0 0 – 0 0.06 0.07 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.08 0.07 0.12 0 0 0.06 0 0 0.05
Cytoplasm 0.85 0.73 0.87 0.79 0.78 0.5 – 0.55 0.45 0.39 0.35 0.35 0.96 0.98 0.97 0.82 0.77 0.66 0.19 0.19 0.15 0.38 0.36 0.3
Endoplasmic Reticulum 0 0.21 0.05 0 0 0 – 0 0 0 0 0 0 0 0 0.05 0.07 0.07 0.31 0.37 0.27 0.17 0.2 0.24
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.15 0 0.05 0.24 0.33 0.63 – 0.53 0.63 0.72 0.76 0.78 0 0 0 0 0.07 0.1 0.27 0.19 0.3 0.27 0.21 0.2
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0.07 0 0.05 0 0 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 15 6 0 0 0 – 0 0 1 0 0 1 3 0 5 4 6 50 45 61 28 47 50
Bud 9 5 5 5 9 21 – 32 41 57 28 43 0 0 1 0 0 2 4 2 3 7 14 25
Bud Neck 7 1 5 0 3 0 – 2 2 3 0 0 4 12 3 0 1 1 15 12 11 10 14 13
Bud Site 1 1 0 0 0 4 – 1 5 20 6 11 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 6 9 7 7 3 – 4 8 5 7 6 7 16 11 3 8 12 16 9 32 16 25 39
Cytoplasm 556 327 375 269 302 270 – 407 323 338 209 251 491 722 770 32 90 67 148 108 81 264 305 253
Endoplasmic Reticulum 16 93 23 6 2 8 – 4 1 2 6 3 12 9 8 2 8 7 238 203 148 116 171 199
Endosome 2 5 0 3 8 0 – 6 3 0 3 1 3 0 2 0 0 4 18 14 16 9 17 17
Golgi 1 1 0 0 0 0 – 0 0 0 0 0 1 1 1 0 1 1 2 7 3 5 4 7
Mitochondria 99 18 23 83 130 336 – 397 456 621 450 556 0 0 0 1 8 10 205 108 167 187 183 170
Nucleus 0 1 1 3 1 2 – 12 5 4 0 2 1 1 2 1 1 2 0 0 1 1 1 0
Nuclear Periphery 1 1 0 1 0 2 – 1 4 0 1 4 0 0 0 0 0 0 2 0 0 2 1 2
Nucleolus 0 0 0 0 0 3 – 0 0 1 3 0 0 0 0 0 0 0 0 0 0 1 0 1
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 0 2 2 3 0 0 1
SpindlePole 2 0 6 2 2 5 – 12 16 18 10 12 3 6 3 0 1 3 6 3 2 4 11 11
Vac/Vac Membrane 12 6 5 7 7 17 – 15 23 27 26 31 1 6 14 0 6 7 32 28 10 30 41 37
Unique Cell Count 653 446 432 342 389 536 743 721 863 596 717 512 738 794 39 117 102 760 556 556 699 857 845
Labelled Cell Count 710 480 458 386 471 671 893 887 1097 749 920 525 776 815 44 128 122 760 556 556 699 857 845


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.7 4.8 4.3 4.0 4.1 3.5 – 3.6 3.3 3.1 3.0 3.1 5.8 5.9 5.8 6.3 6.3 6.0 5.9 6.0 6.5
Std Deviation (1e-4) 0.4 0.7 0.9 1.0 1.4 1.4 – 1.4 1.0 0.7 0.8 0.9 1.0 1.1 1.3 0.9 1.5 1.7 1.2 1.4 1.6
Intensity Change (Log2) – – – -0.11 -0.06 -0.27 – -0.26 -0.36 -0.45 -0.52 -0.47 0.44 0.45 0.43 0.57 0.55 0.49 0.47 0.48 0.59

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.3392 4.5233 4.6829 3.7556 4.5005 4.5365 2.2576 2.2377 1.9983 2.6818 2.6887 1.9999 1.1737 1.5408 1.2363 1.2317 0.9663 1.1152
Actin 0.0149 0.003 0.0104 0.0025 0.0157 0.0029 0.0189 0.0072 0.0093 0.0404 0.0213 0.004 0.0236 0.0124 0.0267 0.0052 0.0066 0.003
Bud 0.0005 0.0009 0.0046 0.0001 0.0002 0.0018 0.0016 0.0038 0.0011 0.0007 0.0016 0.0006 0.0003 0.0005 0.0008 0.0004 0.0008 0.0021
Bud Neck 0.0026 0.001 0.0038 0.002 0.0012 0.0103 0.0074 0.0017 0.0049 0.0106 0.0081 0.0075 0.0024 0.0014 0.001 0.0013 0.0142 0.0104
Bud Periphery 0.001 0.0012 0.0038 0.0004 0.0003 0.001 0.0054 0.0032 0.0028 0.0013 0.004 0.0013 0.0005 0.0006 0.0018 0.0008 0.002 0.0011
Bud Site 0.0072 0.0241 0.0114 0.0005 0.0006 0.0011 0.0076 0.0435 0.0078 0.0065 0.012 0.0011 0.006 0.0261 0.0045 0.0033 0.0032 0.0003
Cell Periphery 0.0043 0.0035 0.0036 0.0038 0.0013 0.0012 0.0022 0.0021 0.0017 0.001 0.0011 0.0007 0.0022 0.0022 0.0017 0.0014 0.0012 0.0009
Cytoplasm 0.2465 0.2824 0.3096 0.3912 0.2924 0.3618 0.3221 0.4732 0.4672 0.3933 0.4756 0.5204 0.38 0.4615 0.4367 0.4992 0.5092 0.4441
Cytoplasmic Foci 0.0274 0.0158 0.0312 0.0491 0.017 0.0369 0.0337 0.0221 0.0297 0.0382 0.0288 0.0311 0.0235 0.0224 0.0162 0.0279 0.0308 0.0328
Eisosomes 0.0011 0.0009 0.0009 0.0003 0.0027 0.0003 0.0004 0.0004 0.0002 0.0008 0.0004 0.0001 0.0006 0.0003 0.0006 0.0002 0.0001 0.0002
Endoplasmic Reticulum 0.108 0.0553 0.0695 0.1795 0.1172 0.0895 0.2155 0.1339 0.1348 0.1689 0.0907 0.1207 0.1647 0.1237 0.1698 0.1341 0.1107 0.1203
Endosome 0.0237 0.0171 0.0258 0.0134 0.0245 0.0238 0.0378 0.0283 0.0398 0.0345 0.051 0.031 0.0265 0.025 0.0215 0.0226 0.021 0.0304
Golgi 0.005 0.0021 0.0035 0.0023 0.004 0.0023 0.0057 0.0045 0.0055 0.0084 0.0103 0.0033 0.0039 0.0031 0.0049 0.0028 0.0033 0.0024
Lipid Particles 0.0249 0.0048 0.0064 0.0088 0.009 0.0133 0.0198 0.0078 0.0094 0.0176 0.0222 0.0094 0.014 0.0052 0.0068 0.008 0.0078 0.0109
Mitochondria 0.0043 0.0026 0.005 0.0009 0.002 0.0032 0.003 0.0028 0.0048 0.0406 0.0082 0.0058 0.0012 0.0007 0.0018 0.0008 0.0009 0.0024
None 0.4833 0.5657 0.4849 0.2856 0.4437 0.4284 0.2489 0.2246 0.2258 0.173 0.2001 0.2221 0.318 0.2949 0.2879 0.2623 0.2208 0.3157
Nuclear Periphery 0.0111 0.0045 0.0069 0.0089 0.0091 0.0042 0.018 0.0117 0.017 0.0082 0.0223 0.0139 0.0114 0.0065 0.0062 0.0068 0.0119 0.0081
Nucleolus 0.0019 0.0011 0.0012 0.0008 0.0014 0.0012 0.0029 0.0019 0.0018 0.0048 0.0038 0.0008 0.0007 0.0004 0.0006 0.0004 0.0024 0.0004
Nucleus 0.0039 0.005 0.0036 0.004 0.0045 0.005 0.0097 0.0093 0.0111 0.0078 0.0113 0.0076 0.0039 0.0039 0.0028 0.0047 0.0188 0.005
Peroxisomes 0.0114 0.0007 0.0021 0.0017 0.0019 0.0012 0.0065 0.001 0.0027 0.0237 0.006 0.0017 0.0065 0.0004 0.0014 0.0007 0.0213 0.0007
Punctate Nuclear 0.01 0.0032 0.0048 0.0386 0.0464 0.006 0.0185 0.0091 0.0108 0.0125 0.0148 0.012 0.0049 0.0038 0.0018 0.0052 0.008 0.0039
Vacuole 0.0058 0.0044 0.0057 0.0047 0.0042 0.004 0.0123 0.007 0.0098 0.0064 0.0047 0.004 0.0043 0.0044 0.004 0.0113 0.0045 0.0041
Vacuole Periphery 0.0013 0.0005 0.0012 0.0007 0.0006 0.0006 0.0021 0.0009 0.0016 0.0011 0.0018 0.0009 0.0006 0.0005 0.0005 0.0006 0.0005 0.0009

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 23.6903 18.6651 14.9157 23.5202 23.9477 22.4732 21.2312 17.6365 18.1565 23.3113
Translational Efficiency 0.6704 0.7142 0.8972 0.5552 0.5384 0.5948 0.6004 0.6841 0.7449 0.6831

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
615 261 2762 1363 2019 2304 273 2796 2634 2565 3035 4159

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 695.66 808.30 797.17 777.29 690.70 725.11 890.64 901.10 691.86 733.57 805.58 860.52
Standard Deviation 74.15 107.42 93.29 129.18 80.30 86.92 95.52 120.69 78.94 92.70 97.24 136.52
Intensity Change Log 2 — 0.216508 0.196505 0.160071 — 0.070141 0.366783 0.383628 — 0.145442 0.283851 0.275776

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000421 0.001591 0.000559 0.007340 0.000762 0.001566 0.000425 0.002857 0.000683 0.001568 0.000547 0.004326
Bud Neck 0.010589 0.023290 0.017362 0.012514 0.008213 0.026923 0.003962 0.035423 0.008768 0.026553 0.016157 0.027915
Bud Site 0.004548 0.014887 0.032249 0.046109 0.002967 0.021481 0.002652 0.065596 0.003336 0.020810 0.029587 0.059210
Cell Periphery 0.000814 0.000461 0.000524 0.001228 0.000423 0.000576 0.000763 0.000782 0.000514 0.000564 0.000545 0.000928
Cytoplasm 0.374886 0.201919 0.450265 0.383125 0.377575 0.299546 0.292302 0.475617 0.376947 0.289612 0.436056 0.445305
Cytoplasmic Foci 0.295665 0.346178 0.046267 0.105121 0.230045 0.264801 0.114603 0.031496 0.245367 0.273081 0.052414 0.055625
Eisosomes 0.001571 0.000680 0.000122 0.000827 0.000779 0.000741 0.000320 0.000342 0.000964 0.000734 0.000139 0.000501
Endoplasmic Reticulum 0.026091 0.033887 0.009978 0.038755 0.044827 0.023843 0.017013 0.011218 0.040452 0.024865 0.010610 0.020243
Endosome 0.017429 0.046018 0.004645 0.011162 0.011790 0.034767 0.011105 0.005558 0.013106 0.035912 0.005226 0.007394
Golgi 0.011876 0.015480 0.000503 0.003704 0.012758 0.019457 0.000310 0.001801 0.012552 0.019052 0.000486 0.002424
Lipid Particles 0.087750 0.074748 0.009933 0.017292 0.087089 0.074638 0.021591 0.007635 0.087243 0.074649 0.010982 0.010800
Mitochondria 0.005847 0.021382 0.001565 0.002120 0.009955 0.029874 0.000474 0.005958 0.008996 0.029009 0.001467 0.004700
Mitotic Spindle 0.004433 0.002991 0.005934 0.008740 0.000763 0.007533 0.000130 0.019357 0.001620 0.007071 0.005412 0.015878
None 0.001676 0.000524 0.002489 0.001319 0.003198 0.002883 0.003068 0.002626 0.002842 0.002643 0.002541 0.002198
Nuclear Periphery 0.002038 0.001862 0.005434 0.001778 0.003377 0.002224 0.005181 0.001472 0.003064 0.002187 0.005412 0.001573
Nuclear Periphery Foci 0.002437 0.005151 0.003719 0.009151 0.002978 0.001747 0.019759 0.002470 0.002852 0.002093 0.005162 0.004660
Nucleolus 0.001211 0.001609 0.001034 0.000517 0.001101 0.001594 0.001729 0.000604 0.001127 0.001595 0.001096 0.000576
Nucleus 0.099413 0.063719 0.346983 0.148304 0.160446 0.097626 0.385088 0.215557 0.146196 0.094176 0.350411 0.193516
Peroxisomes 0.011719 0.029907 0.001594 0.005498 0.007984 0.016736 0.002670 0.003334 0.008856 0.018076 0.001691 0.004043
Vacuole 0.037744 0.109835 0.058311 0.193373 0.031226 0.067444 0.116545 0.108876 0.032748 0.071758 0.063549 0.136568
Vacuole Periphery 0.001844 0.003883 0.000530 0.002025 0.001744 0.004002 0.000310 0.001420 0.001768 0.003990 0.000511 0.001618

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.56 -1.27 -5.58 -4.38 -5.45 -1.77 0.80 -3.58 -2.45 -6.04 -2.40 0.38 -6.14 -4.75 -7.71
Bud Neck -3.05 -3.99 -0.63 2.93 4.66 -11.58 3.75 -14.61 -2.26 -15.66 -11.77 -6.78 -13.81 0.83 -6.47
Bud Site -4.49 -10.73 -10.55 -6.45 -2.16 -11.00 0.24 -19.47 -10.97 -19.44 -11.39 -11.93 -22.24 -11.64 -7.46
Cell Periphery 2.95 2.80 -1.96 -5.63 -5.97 -1.48 -3.26 -4.33 -0.97 0.82 -0.51 -0.30 -5.26 -2.59 -4.61
Cytoplasm 11.46 -6.20 1.84 -10.91 9.98 11.15 6.83 -9.87 -21.05 -11.92 13.73 -7.55 -6.58 -20.48 1.39
Cytoplasmic Foci -3.17 30.93 23.53 17.93 -12.78 -5.86 12.86 45.37 53.58 10.19 -5.02 46.69 48.12 51.61 0.12
Eisosomes 2.85 4.77 2.76 -0.32 -7.51 0.62 8.16 7.63 7.71 0.41 2.59 10.18 5.99 5.61 -7.98
Endoplasmic Reticulum -1.06 4.48 -1.73 -0.02 -8.91 7.09 8.43 12.97 7.41 2.85 6.03 13.50 9.71 3.73 -5.67
Endosome -6.37 7.81 4.48 8.63 -6.65 -15.02 0.08 8.90 20.93 5.54 -15.66 11.17 9.17 21.79 -2.54
Golgi -1.29 9.07 6.73 5.57 -4.80 -5.31 17.26 14.81 17.10 -4.01 -5.66 19.07 15.99 17.60 -5.35
Lipid Particles 1.48 14.08 13.02 7.23 -5.44 3.29 19.33 27.26 26.50 7.60 3.66 29.20 29.84 26.73 1.51
Mitochondria -2.64 6.54 5.17 3.37 -0.49 -10.78 11.01 4.75 14.23 -6.80 -11.62 11.02 6.31 15.29 -5.11
Mitotic Spindle 0.55 -0.65 -1.66 -2.35 -1.53 -5.93 3.25 -9.65 -4.64 -10.10 -4.75 -3.94 -9.42 -4.43 -5.87
None 2.88 -1.74 1.28 -2.34 4.06 0.39 -0.04 1.50 0.73 0.84 0.27 0.77 2.12 1.13 1.60
Nuclear Periphery 0.40 -7.73 0.47 -0.02 10.00 2.63 -2.65 4.50 1.56 5.61 2.37 -6.10 4.39 1.48 11.90
Nuclear Periphery Foci -2.51 -2.72 -8.88 -3.31 -7.14 3.11 -4.76 0.66 -3.62 4.86 2.25 -4.60 -4.79 -8.95 1.24
Nucleolus -0.53 0.60 1.91 2.49 3.94 -2.28 -2.08 2.72 5.02 3.66 -2.12 0.19 3.44 5.84 4.25
Nucleus 4.62 -36.94 -7.03 -10.71 30.51 13.83 -13.06 -10.23 -24.38 9.68 13.16 -36.69 -10.66 -24.46 28.19
Peroxisomes -3.98 7.15 4.77 5.82 -6.34 -8.98 5.48 7.43 16.86 0.11 -9.25 12.11 8.59 17.15 -5.61
Vacuole -8.04 -9.41 -29.73 -12.30 -25.75 -14.23 -10.73 -30.60 -19.59 -2.30 -15.90 -16.57 -42.05 -27.65 -27.67
Vacuole Periphery -2.14 2.81 0.46 2.51 -2.37 -7.67 7.76 2.40 9.41 -3.92 -7.75 6.69 1.97 9.14 -3.64
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative S-adenosylmethionine-dependent methyltransferase; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively; YMR209C is not an essential gene
Localization
Cell Percentages ER (60%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

YMR209C

YMR209C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ymr209c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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Images are not yet available