Standard name
Human Ortholog
Description Nuclear dsRNA-specific ribonuclease (RNase III); involved in rDNA transcription, rRNA processing and U2 snRNA 3' end formation by cleavage of a stem-loop structure at the 3' end of U2 snRNA; involved in polyadenylation-independent transcription termination; involved in the cell wall stress response, regulating the degradation of cell wall integrity and morphogenesis checkpoint genes
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.05 0.05 0.16 0.12 0.13 0.11 0.15 0.06 0.06 0.08 0.13 0.12 0.06 0.06 0.05 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.12 0.25 0.15 0.21 0.59 0.44 0.54 0.47 0.61 0.55 0 0 0 0 0 0 0 0 0 0 0 0.05
Nucleus 0.79 0.79 0.51 0.51 0.51 0.51 0.33 0.42 0.48 0.42 0.46 0.4 0.39 0.31 0.31 0.61 0.62 0.61 0.59 0.61 0.37 0.33 0.22 0.2
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.28 0.23 0.54 0.62 0.46 0.33 0.33 0.26 0.27 0.24 0.27 0.24 0.6 0.58 0.59 0.34 0.26 0.32 0.34 0.29 0.45 0.41 0.35 0.31
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0.05 0.08 0.05 0 0.05 0.06 0.15 0.22 0.26
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 1 1 2 1 0 0 0 0 0 1 0 0 1 0 0 1 2 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 1 1 1 1 2 0 4 7 1 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2 1 0 4 2 14 11 21 10 12 7 7 23 40 41 26 23 14 1 1 0 3 0 2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 10 8 7 0 0 0 1 1 2
Endosome 0 0 0 0 0 1 1 1 0 0 0 0 5 14 15 5 8 2 2 1 2 3 16 16
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 1 1 1
Mitochondria 7 2 5 20 6 19 56 71 48 37 71 61 6 9 3 14 6 6 0 2 1 2 7 13
Nucleus 128 99 21 41 20 45 31 67 43 33 53 44 116 98 112 274 251 160 101 89 24 63 59 56
Nuclear Periphery 2 0 0 0 1 0 4 1 2 5 2 3 1 4 1 4 5 0 0 1 0 1 5 8
Nucleolus 46 29 22 50 18 29 31 41 24 19 31 27 177 183 210 152 105 85 57 41 29 80 95 87
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 5 6 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 2 1 0 1 7 0 1 1 1 3 10 10 6 6 4 0 0 2 4 13 8
Vac/Vac Membrane 3 4 1 2 1 2 2 7 2 1 0 6 1 7 8 21 34 12 5 7 4 29 60 73
Unique Cell Count 163 125 41 80 39 89 95 160 89 78 116 111 295 318 356 451 405 264 172 147 66 196 271 280
Labelled Cell Count 188 135 49 119 50 111 139 218 133 109 169 156 333 371 406 515 446 290 172 147 66 196 271 280


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.3 9.6 6.8 6.4 5.6 5.7 4.3 5.0 4.6 4.6 4.4 4.7 8.3 7.8 7.7 10.6 12.2 12.1 7.3 7.6 8.1
Std Deviation (1e-4) 1.4 2.2 1.5 1.6 1.3 1.4 1.2 1.6 1.0 1.6 1.2 1.7 2.1 2.2 2.0 4.3 4.0 4.7 1.3 1.5 1.4
Intensity Change (Log2) – – – -0.07 -0.28 -0.25 -0.65 -0.45 -0.55 -0.57 -0.61 -0.51 0.3 0.21 0.18 0.65 0.85 0.84 0.11 0.17 0.27


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 1.6 0.4 1.2 0 3.8 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 -0.1 -2.0 -1.1 -0.3 -0.9 -0.6 -1.3 -1.5 -2.6 -2.5 1.2 1.3 1.1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.9 -0.7 -2.3 0 -3.5 0 0 0 0 0.8 0.5 0.7 -2.6 -3.7 -2.7
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.2938 6.7659 6.4364 8.648 6.6831 6.2502 6.5236 6.2242 6.3522 6.04 5.8078 6.2308 7.241 7.7248 7.4021 6.9543 6.9799 7.0237
Actin 0.0006 0 0 0 0.0023 0 0.0016 0.0001 0.0003 0 0 0.0001 0.0027 0 0.0001 0 0.0027 0
Bud 0.0001 0 0 0 0.0001 0.0001 0.0001 0 0.0005 0 0 0 0.0001 0 0 0 0.0003 0
Bud Neck 0.0004 0.0003 0.0002 0.0001 0.0004 0.0007 0.0004 0.0002 0.0003 0.0002 0.001 0.0007 0.0004 0.0002 0.0002 0.0004 0.0134 0.001
Bud Periphery 0.0002 0 0 0 0.0002 0.0001 0.0003 0.0001 0.0003 0 0.0001 0.0001 0.0003 0 0.0001 0.0001 0.0006 0.0001
Bud Site 0.0002 0.0001 0.0001 0 0.0003 0.0001 0.0007 0.0002 0.0003 0.0001 0.0001 0.0001 0.0003 0.0001 0.0001 0.0001 0.0034 0.0001
Cell Periphery 0.0001 0 0.0001 0 0 0 0.0001 0.0001 0.0001 0 0 0.0001 0.0001 0 0 0 0.0002 0.0001
Cytoplasm 0.0002 0 0 0 0.0005 0.0001 0.0007 0.0001 0.0006 0 0 0.0001 0.0003 0.0004 0.0001 0 0.0003 0
Cytoplasmic Foci 0.0008 0 0 0 0.0039 0 0.0061 0.0001 0.003 0 0 0.0001 0.0004 0 0.0003 0 0.001 0
Eisosomes 0 0 0 0 0 0 0 0.0002 0 0 0 0 0 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0002 0 0 0 0.0004 0.0001 0.0004 0 0.0004 0 0 0.0001 0.0006 0.0001 0.0001 0 0.0006 0
Endosome 0.0012 0 0 0 0.0037 0.0006 0.0053 0.0002 0.0008 0 0 0.0004 0.0018 0.0002 0.0003 0.0001 0.0077 0
Golgi 0.0002 0 0 0 0.0011 0 0.0011 0 0.0002 0 0 0.0001 0.0005 0 0.0001 0 0.0018 0
Lipid Particles 0.0012 0 0 0 0.0027 0.0001 0.0047 0.0004 0.002 0 0.0001 0.0006 0.0015 0 0.0016 0.0001 0.003 0.0001
Mitochondria 0.001 0.0001 0.0001 0 0.0005 0.0002 0.0027 0.0001 0.0005 0 0.0002 0.0006 0.0017 0.0001 0.0002 0.0002 0.0031 0.0001
None 0.0002 0 0 0 0.0005 0 0.0017 0.006 0.0006 0 0 0 0.0006 0 0.0001 0 0.0006 0
Nuclear Periphery 0.0019 0.0104 0.0005 0.0003 0.0039 0.0048 0.0026 0.0062 0.005 0.0001 0.0021 0.0016 0.0026 0.001 0.004 0.0177 0.0019 0.0007
Nucleolus 0.4621 0.3989 0.5329 0.4856 0.5251 0.554 0.4948 0.5045 0.5882 0.5784 0.527 0.6104 0.4852 0.4435 0.5308 0.5268 0.4721 0.5844
Nucleus 0.5196 0.5836 0.4602 0.5101 0.4396 0.4356 0.4595 0.4698 0.3864 0.42 0.4579 0.3771 0.4926 0.5504 0.4468 0.4495 0.469 0.4035
Peroxisomes 0.0034 0 0 0 0.0011 0 0.0046 0 0.0013 0 0 0.0001 0.0003 0 0 0 0.0008 0
Punctate Nuclear 0.0044 0.0052 0.0056 0.0037 0.013 0.0023 0.0108 0.0108 0.0081 0.0011 0.0111 0.0068 0.0068 0.0033 0.0147 0.0044 0.0151 0.0095
Vacuole 0.0012 0.0002 0.0002 0 0.0005 0.0008 0.0011 0.0006 0.0006 0.0001 0.0001 0.0006 0.0006 0.0005 0.0003 0.0002 0.0017 0.0002
Vacuole Periphery 0.0006 0.001 0.0001 0 0.0003 0.0004 0.0007 0.0003 0.0004 0 0.0001 0.0002 0.0005 0.0001 0.0002 0.0003 0.0007 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.3904 17.4148 18.6085 17.2919 16.1651 14.0186 11.6214 12.5974 10.7941 18.3527
Translational Efficiency 1.0615 1.2276 1.0279 0.8334 1.1069 1.3554 1.017 0.6623 0.6914 0.787

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1972 1057 1138 1615 1628 1321 105 147 3600 2378 1243 1762

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 838.24 887.97 1027.80 1245.46 819.69 973.91 1245.74 1214.52 829.85 935.71 1046.21 1242.88
Standard Deviation 113.65 160.03 149.83 200.02 112.47 165.44 130.55 217.84 113.49 168.56 160.21 201.75
Intensity Change Log 2 — 0.083148 0.294124 0.571243 — 0.248710 0.603853 0.567236 — 0.167377 0.455557 0.569263

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000214 0.000649 0.000670 0.000833 0.000174 0.000559 0.000724 0.000826 0.000196 0.000599 0.000675 0.000832
Bud Neck 0.006005 0.007741 0.016625 0.031782 0.004202 0.009748 0.013337 0.024104 0.005189 0.008856 0.016347 0.031142
Bud Site 0.000934 0.001294 0.001062 0.003765 0.000235 0.000873 0.001384 0.002926 0.000618 0.001060 0.001089 0.003695
Cell Periphery 0.000094 0.000113 0.000040 0.000078 0.000027 0.000044 0.000021 0.000110 0.000064 0.000075 0.000038 0.000080
Cytoplasm 0.000704 0.002321 0.001381 0.000529 0.001461 0.000333 0.000076 0.000839 0.001046 0.001217 0.001271 0.000555
Cytoplasmic Foci 0.000726 0.000334 0.000068 0.000691 0.000076 0.001230 0.000056 0.007499 0.000432 0.000832 0.000067 0.001259
Eisosomes 0.000033 0.000039 0.000040 0.000049 0.000022 0.000044 0.000043 0.000061 0.000028 0.000042 0.000040 0.000050
Endoplasmic Reticulum 0.002248 0.003379 0.002151 0.001288 0.001109 0.002489 0.001520 0.001947 0.001733 0.002885 0.002097 0.001343
Endosome 0.000698 0.000618 0.000183 0.000995 0.000155 0.001063 0.000133 0.022791 0.000452 0.000865 0.000179 0.002813
Golgi 0.000226 0.000374 0.000193 0.000612 0.000141 0.000770 0.000308 0.002954 0.000188 0.000594 0.000203 0.000807
Lipid Particles 0.000154 0.000287 0.000098 0.000160 0.000088 0.000819 0.000064 0.002289 0.000124 0.000583 0.000095 0.000338
Mitochondria 0.000952 0.001380 0.000928 0.004087 0.000628 0.002693 0.000881 0.012787 0.000806 0.002109 0.000924 0.004813
Mitotic Spindle 0.002036 0.001940 0.002365 0.011226 0.000250 0.009709 0.001951 0.015242 0.001229 0.006256 0.002330 0.011561
None 0.003033 0.004230 0.002283 0.001387 0.003610 0.001174 0.000729 0.002920 0.003294 0.002533 0.002151 0.001515
Nuclear Periphery 0.000459 0.000326 0.000267 0.001339 0.000259 0.000591 0.000177 0.000654 0.000369 0.000473 0.000259 0.001282
Nuclear Periphery Foci 0.000448 0.002208 0.000321 0.000548 0.000695 0.000676 0.000271 0.000855 0.000560 0.001357 0.000317 0.000574
Nucleolus 0.266441* 0.239496* 0.274854* 0.335502* 0.285070* 0.243704* 0.523790* 0.263455* 0.274866* 0.241834* 0.295882* 0.329491*
Nucleus 0.711082* 0.731041* 0.694584* 0.600155* 0.701174* 0.719738* 0.449495* 0.605772* 0.706602* 0.724762* 0.673880* 0.600623*
Peroxisomes 0.000892 0.001052 0.001081 0.001280 0.000355 0.001610 0.003151 0.006990 0.000649 0.001362 0.001256 0.001756
Vacuole 0.001716 0.000609 0.000576 0.001916 0.000118 0.001191 0.001565 0.018354 0.000994 0.000932 0.000659 0.003288
Vacuole Periphery 0.000903 0.000570 0.000231 0.001780 0.000150 0.000941 0.000324 0.006623 0.000563 0.000776 0.000239 0.002184

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -9.16 -14.37 -13.06 -4.81 -2.92 -6.40 -7.75 -6.06 -4.10 -1.05 -10.07 -17.22 -14.88 -6.35 -3.09
Bud Neck -2.00 -10.99 -20.79 -19.40 -11.59 -6.56 -6.11 -6.26 -5.22 -1.76 -5.95 -13.57 -22.71 -19.80 -11.57
Bud Site -0.93 -1.66 -4.07 -3.52 -3.68 -4.42 -5.22 -5.96 -5.12 -1.54 -2.34 -5.76 -5.22 -4.48 -3.86
Cell Periphery -0.68 2.51 0.75 1.60 -3.28 -1.99 -1.77 -2.96 -2.34 -2.41 -0.76 1.79 -1.09 -0.34 -3.75
Cytoplasm -2.05 -1.28 -0.02 2.05 1.29 1.49 2.76 -0.39 -1.70 -2.68 -0.82 -0.25 0.94 1.47 0.93
Cytoplasmic Foci 1.15 2.07 0.71 -0.47 -1.69 -2.92 -0.94 -1.86 -1.35 -1.70 -1.15 1.93 -0.92 0.03 -2.37
Eisosomes -2.41 -4.11 -5.55 -3.64 -1.99 -11.64 -7.00 -4.89 -2.53 -1.09 -8.81 -8.88 -9.68 -3.29 -2.24
Endoplasmic Reticulum -3.25 -0.62 2.49 8.00 5.44 -5.71 -2.95 -3.40 -1.28 -0.89 -5.23 -3.56 0.22 6.26 4.51
Endosome 0.47 2.72 -0.12 -0.57 -2.65 -3.34 -2.66 -2.23 -2.07 -2.20 -1.92 2.36 -2.47 -1.69 -3.00
Golgi -1.10 -0.05 -1.74 -0.72 -1.83 -2.66 -5.12 -2.23 -1.39 -1.66 -2.79 -1.84 -2.69 -0.28 -2.33
Lipid Particles -0.85 0.90 0.22 0.95 -0.63 -2.30 -1.47 -1.62 -0.78 -1.51 -2.40 0.32 -1.41 1.54 -1.60
Mitochondria -1.22 -0.17 -4.88 -4.17 -5.16 -3.26 -3.48 -1.61 -1.20 -1.46 -3.35 -1.41 -5.17 -3.00 -4.95
Mitotic Spindle -0.01 -1.28 -5.49 -5.41 -4.28 -4.47 -2.37 -2.20 -0.90 -0.62 -3.95 -2.61 -6.40 -3.35 -4.25
None -1.34 1.32 2.53 4.03 1.70 3.79 4.00 -0.33 -2.86 -2.93 1.52 2.44 3.53 2.17 1.00
Nuclear Periphery 0.91 1.02 -3.65 -4.71 -4.80 -1.67 -1.86 -3.75 -1.23 -2.08 -0.85 0.42 -4.57 -3.73 -4.96
Nuclear Periphery Foci -1.75 0.09 -0.40 1.69 -0.48 0.11 0.99 -0.89 -0.91 -1.04 -1.71 1.22 -0.28 1.54 -1.05
Nucleolus 3.18 -1.52 -5.07 -7.35 -2.83 5.16 -5.64 1.77 -0.10 5.68 5.73 -2.31 -3.83 -7.96 -0.93
Nucleus -2.31 2.89 11.35 12.25 6.92 -2.19 7.54 3.01 3.73 -3.66 -3.00 4.56 12.03 13.67 5.33
Peroxisomes -0.43 -0.86 -1.39 -2.20 -1.92 -2.60 -4.00 -2.39 -1.72 -0.04 -2.15 -3.91 -3.99 -1.01 -0.79
Vacuole 2.37 1.88 -1.14 -5.89 -4.98 -2.99 -1.55 -2.67 -2.46 -1.56 -0.14 -0.53 -3.95 -3.92 -3.47
Vacuole Periphery 1.05 2.21 -1.60 -3.30 -4.71 -2.37 -5.90 -2.12 -1.67 -1.95 -0.87 1.81 -3.55 -2.78 -5.02
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Nuclear dsRNA-specific ribonuclease (RNase III); involved in rDNA transcription, rRNA processing and U2 snRNA 3' end formation by cleavage of a stem-loop structure at the 3' end of U2 snRNA; involved in polyadenylation-independent transcription termination; involved in the cell wall stress response, regulating the degradation of cell wall integrity and morphogenesis checkpoint genes
Localization
Cell Percentages nucleus (59%), nucleolus (11%), mixed (30%)
Cell Cycle Regulation Yes
nucleolus - S/G2 (3.6e-06)
nucleus - T/G1 (9.2e-05)
Subcompartmental Group N/A

Rnt1

Rnt1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rnt1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available