Standard name
Human Ortholog
Description Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p; NGL2 has a paralog, NGL3, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.96 0.99 0.95 1.0 0.94 0.89 0.77 0.82 0.73 0.68 0.56 0.7 1.0 0.99 0.99 0.98 0.96 0.96 0.91 0.95 0.94 0.93 0.87 0.84
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0 0.08 0.1 0.1 0.3 0.48 0.38 0.5 0.56 0.72 0.52 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 1 4
Bud 1 2 5 0 4 1 2 3 1 4 0 5 1 1 1 1 0 0 0 0 0 0 3 6
Bud Neck 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 1 1 0 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 3 0 0 0 3 1 1 0 0 1 1 1 5 3 8 11 7 0 0 0 0 0 1
Cytoplasm 224 237 113 41 126 149 123 187 80 86 92 109 472 510 515 558 570 494 223 230 111 227 272 305
Endoplasmic Reticulum 1 1 0 0 1 2 1 0 0 0 0 0 1 2 1 27 22 22 1 0 0 2 1 6
Endosome 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 4 7 3 0 0 2 6 5
Golgi 1 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 1 2 1 0 0 1 0
Mitochondria 11 0 9 4 14 51 77 87 55 71 119 81 0 2 1 5 6 3 1 3 2 2 6 9
Nucleus 0 0 0 0 0 1 1 1 1 0 4 1 0 1 2 3 5 3 0 1 0 0 0 0
Nuclear Periphery 2 1 0 0 0 0 0 1 0 2 0 1 0 0 0 0 0 0 1 0 0 1 0 0
Nucleolus 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 0 0 0 0 0 0 1 0 2 0 0 0 2 1 0 1 0 0 0 6 7
Vac/Vac Membrane 0 0 0 0 0 0 1 0 0 0 2 1 1 0 1 10 22 9 7 1 0 3 6 11
Unique Cell Count 233 240 119 41 134 168 160 227 109 126 165 156 473 516 520 569 593 512 245 243 118 245 312 365
Labelled Cell Count 243 245 129 45 145 207 207 281 139 164 219 201 476 524 524 616 644 546 245 243 118 245 312 365


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.0 6.1 4.6 4.3 4.2 3.6 3.0 3.4 3.4 3.5 3.1 3.2 6.1 5.8 5.8 5.8 7.0 6.4 5.0 4.8 5.6
Std Deviation (1e-4) 0.7 0.7 0.8 0.6 1.3 0.8 0.7 1.0 0.8 1.8 0.9 1.3 0.9 1.1 1.2 1.2 1.4 1.1 0.9 1.0 1.3
Intensity Change (Log2) – – – -0.1 -0.14 -0.38 -0.65 -0.45 -0.46 -0.42 -0.57 -0.55 0.39 0.33 0.31 0.31 0.58 0.47 0.1 0.05 0.27

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.5 -0.3 -1.9 -4.1 -3.3 -4.5 -5.3 -7.3 -5.2 4.4 2.8 3.1 2.0 0.6 0.8
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin – – – – – – 0.055 0.014 0.0432 0.0083 0.0137 0.0116 – – – – – –
Bud – – – – – – 0.002 0.0008 0.0009 0.0003 0.0012 0.0068 – – – – – –
Bud Neck – – – – – – 0.0116 0.0003 0.0005 0.0005 0.0008 0.0003 – – – – – –
Bud Periphery – – – – – – 0.0021 0.0005 0.0013 0.0002 0.0019 0.0061 – – – – – –
Bud Site – – – – – – 0.0057 0.0087 0.0082 0.0009 0.0038 0.0002 – – – – – –
Cell Periphery – – – – – – 0.0005 0.0003 0.001 0.0001 0.0004 0 – – – – – –
Cytoplasm – – – – – – 0.3779 0.6194 0.567 0.5929 0.4579 0.68 – – – – – –
Cytoplasmic Foci – – – – – – 0.0422 0.018 0.0173 0.0419 0.0435 0.0093 – – – – – –
Eisosomes – – – – – – 0.0003 0.0001 0.0003 0 0.0001 0 – – – – – –
Endoplasmic Reticulum – – – – – – 0.007 0.0035 0.0035 0.0025 0.0024 0.0013 – – – – – –
Endosome – – – – – – 0.0265 0.006 0.0219 0.0283 0.0361 0.0054 – – – – – –
Golgi – – – – – – 0.008 0.0055 0.0145 0.0131 0.023 0.0044 – – – – – –
Lipid Particles – – – – – – 0.0312 0.0006 0.0012 0.0066 0.0566 0.0026 – – – – – –
Mitochondria – – – – – – 0.0072 0.0007 0.0067 0.0012 0.0124 0.0024 – – – – – –
None – – – – – – 0.3736 0.3108 0.3012 0.2861 0.3289 0.2616 – – – – – –
Nuclear Periphery – – – – – – 0.0155 0.0009 0.0006 0.0017 0.001 0.0004 – – – – – –
Nucleolus – – – – – – 0.0009 0.0001 0.0001 0.0001 0.0002 0 – – – – – –
Nucleus – – – – – – 0.0079 0.001 0.0007 0.0015 0.0006 0.0009 – – – – – –
Peroxisomes – – – – – – 0.0091 0.0062 0.0062 0.0085 0.012 0.0055 – – – – – –
Punctate Nuclear – – – – – – 0.0084 0.0009 0.0004 0.0013 0.0013 0.0004 – – – – – –
Vacuole – – – – – – 0.0039 0.0014 0.0031 0.0034 0.0015 0.0006 – – – – – –
Vacuole Periphery – – – – – – 0.0034 0.0002 0.0003 0.0006 0.0007 0.0001 – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 18.889 18.4786 13.7119 16.0096 15.2488 18.5224 20.9386 18.698 20.2013 16.7878
Translational Efficiency 1.4065 1.4617 1.3812 1.0335 1.1269 1.4083 1.3002 1.1707 0.968 1.1513

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1479 657 1229 86 369 1027 711 738 1848 1684 1940 824

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 735.41 687.44 941.18 1041.69 818.38 836.55 1015.61 962.77 751.98 778.38 968.46 971.01
Standard Deviation 85.83 115.37 128.71 124.58 88.01 117.36 124.75 159.63 92.43 137.42 132.23 158.19
Intensity Change Log 2 — -0.097315 0.355922 0.502305 — 0.031681 0.311504 0.234420 — -0.027938 0.332697 0.367422

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000156 0.000252 0.000183 0.003444 0.000902 0.000794 0.000143 0.001128 0.000305 0.000583 0.000168 0.001370
Bud Neck 0.007421 0.013906 0.002499 0.016576 0.004715 0.015819 0.002441 0.003008 0.006880 0.015073 0.002478 0.004424
Bud Site 0.003779 0.019961 0.009931 0.070813 0.007006 0.023024 0.010465 0.016312 0.004423 0.021829 0.010127 0.022000
Cell Periphery 0.000121 0.000094 0.000124 0.000282 0.000182 0.000088 0.000082 0.000442 0.000133 0.000090 0.000109 0.000425
Cytoplasm 0.638646 0.595487 0.651777 0.174750 0.572679 0.592274 0.671672 0.626123 0.625474 0.593527 0.659068 0.579014
Cytoplasmic Foci 0.131461 0.137856 0.025679 0.098864 0.239815 0.161273 0.011585 0.036094 0.153097 0.152137 0.020513 0.042646
Eisosomes 0.000085 0.000056 0.000039 0.000080 0.000131 0.000065 0.000024 0.000027 0.000094 0.000061 0.000034 0.000033
Endoplasmic Reticulum 0.000652 0.000632 0.001085 0.004616 0.001110 0.000591 0.001016 0.000701 0.000743 0.000607 0.001060 0.001110
Endosome 0.007131 0.024980 0.003141 0.060797 0.012331 0.018457 0.002623 0.020281 0.008170 0.021002 0.002951 0.024509
Golgi 0.000928 0.001845 0.001073 0.065265 0.001093 0.004845 0.000192 0.012646 0.000961 0.003675 0.000750 0.018138
Lipid Particles 0.003205 0.002842 0.001275 0.003745 0.003601 0.001966 0.000808 0.000726 0.003284 0.002308 0.001104 0.001041
Mitochondria 0.001195 0.002075 0.000365 0.019872 0.000364 0.002041 0.000369 0.004354 0.001029 0.002054 0.000366 0.005974
Mitotic Spindle 0.000663 0.002485 0.011513 0.172668 0.000502 0.013764 0.023968 0.035698 0.000631 0.009364 0.016077 0.049993
None 0.007446 0.008013 0.006055 0.002688 0.000823 0.001357 0.009063 0.029742 0.006123 0.003954 0.007157 0.026919
Nuclear Periphery 0.000302 0.000269 0.000785 0.001062 0.000229 0.000216 0.000959 0.000388 0.000287 0.000237 0.000849 0.000459
Nuclear Periphery Foci 0.000346 0.001288 0.001552 0.006122 0.001498 0.000645 0.001893 0.002099 0.000576 0.000896 0.001677 0.002519
Nucleolus 0.000804 0.004062 0.000387 0.000829 0.000368 0.000384 0.000456 0.000431 0.000717 0.001819 0.000412 0.000473
Nucleus 0.128099 0.056796 0.184655 0.068130 0.072729 0.041314 0.117898 0.080209 0.117043 0.047354 0.160189 0.078948
Peroxisomes 0.001351 0.005323 0.000372 0.022271 0.001617 0.006373 0.000160 0.003630 0.001404 0.005964 0.000294 0.005575
Vacuole 0.065698 0.119270 0.097362 0.198187 0.077259 0.113061 0.142496 0.123779 0.068006 0.115484 0.113904 0.131545
Vacuole Periphery 0.000513 0.002509 0.000148 0.008940 0.001044 0.001649 0.001688 0.002181 0.000619 0.001984 0.000712 0.002886

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.21 -0.64 -2.37 -2.08 -2.27 0.18 0.97 0.35 0.34 -3.06 -1.11 0.54 -1.81 -0.46 -3.50
Bud Neck -3.57 5.32 0.66 3.21 -2.12 -6.36 1.82 1.03 8.47 -1.51 -6.66 6.08 4.38 9.85 -1.79
Bud Site -6.61 -2.64 -3.93 -1.22 -3.16 -6.30 -0.19 -2.30 4.27 -2.32 -10.86 -2.85 -5.82 3.63 -3.24
Cell Periphery 3.89 1.46 -0.25 -1.96 -0.93 6.54 7.21 0.23 -0.88 -0.97 6.89 5.32 -0.34 -0.91 -0.79
Cytoplasm 4.14 5.48 13.25 10.81 11.18 -0.74 6.01 5.51 7.06 -0.47 4.64 9.64 13.96 9.82 6.85
Cytoplasmic Foci -0.49 28.43 10.96 9.91 -3.08 7.75 25.38 23.48 23.79 -6.11 0.73 36.84 31.40 28.08 -3.41
Eisosomes 5.65 11.08 5.27 0.51 -2.61 5.95 8.60 9.05 8.30 2.16 7.53 14.31 15.09 8.87 1.95
Endoplasmic Reticulum -0.03 -6.49 -2.20 -2.21 -0.33 1.90 -2.46 1.10 -1.58 6.24 0.85 -7.30 -1.66 -2.66 6.32
Endosome -7.23 7.46 -1.73 2.29 -2.91 -2.77 9.44 2.77 4.82 -3.41 -8.71 11.10 0.11 6.31 -3.87
Golgi -3.12 0.54 -1.24 -1.12 -1.27 -4.05 5.85 -1.82 0.73 -2.59 -4.68 1.46 -2.29 -0.42 -2.60
Lipid Particles 0.86 4.97 0.46 -0.36 -4.10 3.56 6.83 7.24 2.85 1.85 2.65 6.51 6.55 4.21 0.37
Mitochondria -1.30 2.30 -0.93 -0.52 -1.41 -4.31 -0.48 -1.38 0.83 -1.32 -2.26 2.24 -0.63 0.67 -1.72
Mitotic Spindle -3.48 -4.79 -4.33 -4.25 -3.96 -4.86 -5.26 -7.64 -4.46 -3.62 -5.27 -7.06 -8.68 -6.73 -6.09
None -0.06 1.84 1.82 1.52 0.54 -1.24 -8.43 -5.42 -5.18 -3.19 1.87 0.65 -2.98 -4.07 -3.51
Nuclear Periphery 0.43 -14.96 -6.58 -6.75 -1.61 0.05 -17.65 -13.43 -13.56 7.55 1.09 -21.42 -13.27 -15.00 4.53
Nuclear Periphery Foci -2.31 -11.77 -4.27 -3.27 -3.11 3.08 -2.53 -4.15 -7.08 -0.22 -1.80 -8.34 -9.18 -6.41 -2.92
Nucleolus -2.93 4.58 2.34 3.22 -1.30 -0.22 -0.03 -1.66 -1.64 -1.65 -2.52 4.33 -1.04 0.81 -1.74
Nucleus 13.42 -11.41 6.76 -0.04 12.88 5.09 -12.01 -6.80 -13.06 5.70 18.40 -14.41 -0.21 -12.10 10.94
Peroxisomes -4.35 3.43 -1.21 0.31 -1.66 -6.02 5.54 0.00 5.54 -3.57 -7.36 4.64 -0.95 5.49 -3.69
Vacuole -9.27 -13.58 -10.86 -8.74 -8.26 -6.91 -17.81 -17.04 -12.87 0.87 -13.02 -22.13 -21.39 -14.93 -7.80
Vacuole Periphery -5.22 9.95 -0.92 0.90 -1.32 -1.13 1.10 0.87 2.31 -0.39 -5.30 2.33 -0.46 3.31 -1.67
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p; NGL2 has a paralog, NGL3, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (84%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ngl2

Ngl2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ngl2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available