Standard name
Human Ortholog
Description Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to endosomes
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0.09 0 0.08 – 0.07 0.06 0.1 0.08 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.12 0.14 0.43 0.23 0.29 0.38 – 0.48 0.48 0.53 0.56 0.58 0.28 0.18 0.2 0.45 0.43 0.43 0 0.05 0.09 0.1 0.07 0.08
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0
Endosome 0.47 0.5 0 0.19 0.33 0.14 – 0.06 0 0 0 0 0.52 0.65 0.61 0.4 0.47 0.49 0.73 0.68 0.55 0.57 0.63 0.63
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.23 0.14 0.44 0.39 0.16 0.43 – 0.36 0.53 0.45 0.54 0.49 0.07 0 0 0.05 0 0 0 0 0.08 0.08 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0.1 0 0.07 – 0 0 0 0 0 0 0 0.07 0 0.05 0 0 0 0 0 0 0
SpindlePole 0.32 0.15 0.22 0.32 0.33 0.19 – 0.18 0.12 0.11 0.09 0.08 0.14 0.26 0.27 0.19 0.19 0.2 0.1 0.08 0.1 0.08 0.1 0.06
Vac/Vac Membrane 0.11 0.32 0 0 0 0 – 0 0 0 0 0 0.19 0.1 0.1 0.13 0.08 0.07 0.06 0.09 0.1 0.08 0.12 0.12
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 2 1 0 2 0 – 0 1 3 0 0 3 4 1 0 2 3 1 1 1 1 2 1
Bud 9 6 5 19 16 41 – 66 34 59 32 34 6 10 9 1 4 1 2 1 0 1 4 4
Bud Neck 4 0 2 1 3 7 – 16 5 9 2 5 0 2 3 0 1 2 2 2 1 1 5 4
Bud Site 1 0 0 2 1 2 – 0 1 2 1 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 48 35 49 48 117 200 – 429 267 330 223 360 90 96 126 48 46 70 17 13 13 17 38 53
Endoplasmic Reticulum 3 2 1 0 3 0 – 4 3 0 0 0 2 2 11 3 8 6 3 0 0 0 0 3
Endosome 185 128 0 41 132 72 – 57 14 21 8 4 167 355 390 42 51 80 348 204 84 102 341 442
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 1 2 0 1 0 4
Mitochondria 91 37 51 83 65 228 – 327 299 276 214 303 21 12 15 5 3 4 15 12 12 14 16 24
Nucleus 2 1 0 0 0 0 – 5 2 1 0 2 0 1 1 0 0 1 0 2 0 1 4 6
Nuclear Periphery 0 1 1 1 0 0 – 1 0 0 0 0 1 1 5 1 0 1 0 0 0 0 0 2
Nucleolus 17 5 0 2 9 1 – 8 0 0 0 0 4 10 15 1 2 1 4 3 1 2 6 6
Peroxisomes 9 2 0 22 18 35 – 20 2 11 3 4 4 0 42 0 5 0 2 2 0 1 0 1
SpindlePole 125 38 25 67 133 98 – 163 66 69 36 52 44 140 174 20 21 32 46 23 15 15 51 44
Vac/Vac Membrane 44 81 0 5 13 17 – 15 12 13 5 12 61 53 61 14 9 12 26 28 15 15 64 85
Unique Cell Count 394 256 115 212 404 528 897 561 617 395 621 322 544 639 106 108 164 480 302 153 181 545 699
Labelled Cell Count 541 338 135 291 512 701 1111 706 794 524 781 403 686 853 135 152 214 480 302 153 181 545 699


Endosome

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.9 5.2 3.4 3.6 4.0 3.4 – 3.5 3.1 3.5 3.4 3.1 5.1 5.2 5.0 6.7 7.0 6.5 5.4 5.4 5.7
Std Deviation (1e-4) 6.5 0.8 0.7 1.0 1.1 1.3 – 1.1 2.8 4.1 3.8 0.5 0.9 0.8 0.8 1.2 4.5 1.6 2.8 2.5 2.5
Intensity Change (Log2) – – – 0.09 0.26 -0.0 – 0.03 -0.14 0.06 0.0 -0.14 0.59 0.63 0.56 0.98 1.06 0.94 0.67 0.68 0.74

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -3.8 -2.8 -0.9 – 1.1 1.0 2.1 2.6 3.0 -2.9 -5.9 -5.4 0.4 0 0
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 – 0 0 0 0 0 9.8 12.8 12.1 7.5 8.4 8.9
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 – 0 0 0 0 0 -9.4 -14.0 -14.7 -6.8 -7.2 -8.7
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 2.8 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 -2.0 0.9 1.2 -0.5 -0.4 -0.5
Vacuole 0 0 0 – 0 0 0 0 0 5.0 3.5 3.5 4.0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.3288 1.4538 1.3465 1.7106 1.5734 1.3162 0.0645 0.3297 0.2956 0.2185 0.0131 0.1563 2.2639 2.2698 2.396 2.2172 2.324 1.8245
Actin 0.007 0.0001 0.0069 0.0074 0.0276 0.0028 0.0145 0.0001 0.0048 0.004 0.0011 0.0017 0.0534 0.0001 0.0129 0.0105 0.0004 0.0001
Bud 0.0002 0.0002 0.0041 0.0001 0.0005 0.0001 0.0006 0.0001 0.0029 0.0013 0.0004 0.0001 0.0005 0.0003 0.0002 0.0006 0.0001 0.0001
Bud Neck 0.0015 0.0008 0.0022 0.0053 0.0013 0.0005 0.0006 0.0008 0.0009 0.0051 0.0002 0.001 0.0037 0.0016 0.0003 0.001 0.0009 0.0007
Bud Periphery 0.0002 0.0003 0.0011 0.0002 0.001 0.0001 0.0007 0.0001 0.0037 0.0019 0.0004 0.0001 0.0007 0.0004 0.0002 0.0008 0.0001 0.0001
Bud Site 0.0013 0.0017 0.0015 0.0009 0.0013 0.0002 0.0031 0.002 0.0091 0.0237 0.0016 0.0016 0.0104 0.003 0.0015 0.0022 0.0019 0.0004
Cell Periphery 0.0001 0.0001 0.0001 0.0001 0.0002 0 0.0003 0.0002 0.0004 0.0012 0.0001 0.0001 0.0004 0.0004 0.0001 0.0001 0.0001 0.0001
Cytoplasm 0.04 0.0554 0.0675 0.0059 0.0064 0.0392 0.0855 0.0925 0.097 0.1019 0.0247 0.0319 0.071 0.1185 0.1333 0.1001 0.1765 0.122
Cytoplasmic Foci 0.234 0.3282 0.2468 0.3215 0.3324 0.3295 0.2197 0.2799 0.2125 0.1966 0.1848 0.28 0.2505 0.2414 0.2435 0.3261 0.4321 0.3087
Eisosomes 0.0001 0 0.0004 0.0001 0.0003 0 0.0002 0.0001 0.0001 0.0001 0.0001 0 0.0004 0.0001 0.0001 0.0002 0 0
Endoplasmic Reticulum 0.0061 0.0013 0.0021 0.0012 0.0053 0.0012 0.0057 0.0024 0.0067 0.0013 0.0044 0.0017 0.0067 0.0044 0.0043 0.0015 0.0002 0.0021
Endosome 0.4119 0.3848 0.391 0.398 0.2778 0.3663 0.3548 0.3739 0.3871 0.4236 0.405 0.4494 0.3079 0.2852 0.2849 0.2707 0.2719 0.3469
Golgi 0.0214 0.0204 0.0365 0.0364 0.0384 0.0215 0.0313 0.0166 0.0291 0.0331 0.0307 0.0354 0.0164 0.0108 0.0326 0.0326 0.0398 0.0212
Lipid Particles 0.1321 0.0999 0.0934 0.1129 0.0942 0.1235 0.1303 0.1023 0.073 0.0658 0.1219 0.1235 0.0858 0.076 0.0576 0.0742 0.0413 0.0848
Mitochondria 0.0102 0.0043 0.0027 0.003 0.0192 0.0012 0.0206 0.0008 0.0211 0.0454 0.0231 0.0059 0.0089 0.0047 0.0068 0.058 0.0015 0.0016
None 0.0278 0.0173 0.0571 0.0039 0.029 0.0225 0.0339 0.0685 0.0845 0.0572 0.1276 0.022 0.0904 0.1651 0.1553 0.0053 0.0004 0.0757
Nuclear Periphery 0.0129 0.0013 0.0069 0.0021 0.0317 0.0043 0.018 0.0015 0.0044 0.0007 0.0038 0.0031 0.0139 0.0027 0.004 0.0022 0.0001 0.0009
Nucleolus 0.0021 0.0059 0.0011 0.0007 0.0018 0.0005 0.0041 0.0015 0.0008 0.0007 0.0005 0.0019 0.0031 0.0055 0.0006 0.0035 0.0005 0.0005
Nucleus 0.0129 0.0021 0.0047 0.0009 0.0047 0.0008 0.0063 0.0026 0.002 0.0007 0.0009 0.0013 0.0164 0.0063 0.0043 0.0233 0.0002 0.0013
Peroxisomes 0.0485 0.0483 0.0548 0.0879 0.1064 0.0647 0.0152 0.0235 0.0241 0.0213 0.0375 0.0134 0.0216 0.0187 0.0437 0.0556 0.0275 0.0169
Punctate Nuclear 0.0147 0.0105 0.004 0.0073 0.0112 0.0121 0.0168 0.0047 0.0025 0.0007 0.0065 0.012 0.0151 0.0046 0.0042 0.0038 0.0022 0.0039
Vacuole 0.0127 0.0154 0.0129 0.0029 0.0049 0.0078 0.0301 0.0239 0.027 0.0103 0.0197 0.0105 0.0188 0.0471 0.0082 0.0232 0.0017 0.0105
Vacuole Periphery 0.0024 0.0017 0.0021 0.0011 0.0044 0.0013 0.0077 0.002 0.0064 0.0034 0.005 0.0032 0.0041 0.0031 0.0014 0.0044 0.0007 0.0018

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.1418 9.5765 7.1062 8.9828 2.3149 10.7067 8.8759 6.5352 12.5082 13.4791
Translational Efficiency 1.635 1.0961 1.8217 1.3226 6.8262 2.0781 1.3351 1.6037 1.5258 1.5603

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1038 1340 746 983 1323 1465 1326 826 2361 2805 2072 1809

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 632.41 758.54 918.48 837.54 671.11 762.11 873.79 797.73 654.10 760.40 889.88 819.36
Standard Deviation 71.24 107.35 105.82 114.88 93.48 100.29 100.60 108.66 86.59 103.74 104.73 113.83
Intensity Change Log 2 — 0.262365 0.538388 0.405298 — 0.183450 0.380737 0.249351 — 0.222275 0.459375 0.327116

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000109 0.000131 0.000299 0.000990 0.000137 0.000074 0.000222 0.000199 0.000125 0.000101 0.000250 0.000629
Bud Neck 0.055004 0.008663 0.026906 0.019487 0.024426 0.012344 0.015905 0.039007 0.037870 0.010585 0.019866 0.028400
Bud Site 0.004602 0.005555 0.010816 0.020377 0.003986 0.004552 0.010416 0.012304 0.004257 0.005031 0.010560 0.016691
Cell Periphery 0.000225 0.000024 0.000047 0.000066 0.000057 0.000065 0.000022 0.000199 0.000131 0.000046 0.000031 0.000127
Cytoplasm 0.083976 0.021568 0.012869 0.088724 0.042808 0.018431 0.014111 0.153740 0.060907 0.019930 0.013664 0.118410
Cytoplasmic Foci 0.248422 0.171319 0.109335 0.183239 0.214393 0.145698 0.131109 0.144127 0.229354 0.157938 0.123270 0.165380
Eisosomes 0.000279 0.000029 0.000060 0.000055 0.000099 0.000059 0.000024 0.000191 0.000178 0.000045 0.000037 0.000117
Endoplasmic Reticulum 0.000838 0.000384 0.001129 0.002053 0.000256 0.000421 0.000492 0.000950 0.000512 0.000404 0.000721 0.001549
Endosome 0.355313 0.622060 0.524316 0.317248 0.517631 0.631759 0.605403 0.250417 0.446269 0.627126 0.576208 0.286733
Golgi 0.026392 0.029505 0.007330 0.005073 0.017704 0.031620 0.006625 0.004415 0.021524 0.030610 0.006879 0.004773
Lipid Particles 0.066939 0.013257 0.009957 0.010152 0.053399 0.042180 0.006322 0.017686 0.059352 0.028363 0.007631 0.013592
Mitochondria 0.019514 0.010403 0.002326 0.001486 0.010210 0.015316 0.001943 0.007540 0.014300 0.012969 0.002081 0.004250
Mitotic Spindle 0.000380 0.021229 0.043823 0.050965 0.003112 0.007844 0.052148 0.023152 0.001911 0.014238 0.049151 0.038265
None 0.001945 0.000231 0.000242 0.001029 0.000871 0.000225 0.000145 0.004794 0.001343 0.000228 0.000180 0.002748
Nuclear Periphery 0.000860 0.000302 0.001255 0.001389 0.000390 0.000327 0.000807 0.001727 0.000597 0.000315 0.000969 0.001543
Nuclear Periphery Foci 0.000424 0.001781 0.014134 0.010379 0.001399 0.003032 0.012139 0.003223 0.000970 0.002434 0.012857 0.007111
Nucleolus 0.002583 0.001411 0.017850 0.003404 0.003149 0.002434 0.006556 0.011144 0.002900 0.001945 0.010622 0.006938
Nucleus 0.031397 0.003543 0.034542 0.024452 0.012611 0.004156 0.004814 0.128987 0.020870 0.003863 0.015517 0.072183
Peroxisomes 0.046161 0.035004 0.070049 0.065670 0.052694 0.036010 0.050748 0.032991 0.049822 0.035530 0.057697 0.050749
Vacuole 0.051095 0.048605 0.109231 0.192124 0.038699 0.038879 0.078540 0.160976 0.044149 0.043525 0.089590 0.177902
Vacuole Periphery 0.003542 0.004996 0.003484 0.001638 0.001968 0.004574 0.001509 0.002233 0.002660 0.004776 0.002220 0.001909

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.19 -4.56 -7.57 -7.27 -4.86 1.86 -2.24 -2.60 -4.45 -0.17 0.88 -4.27 -7.83 -8.33 -4.71
Bud Neck 10.74 5.43 7.28 -7.08 1.96 5.03 2.53 -2.49 -5.92 -4.32 11.67 6.36 3.56 -8.55 -2.63
Bud Site -0.81 -4.23 -7.99 -8.54 -4.53 -0.57 -7.15 -4.13 -3.57 -0.15 -1.04 -7.83 -9.07 -8.45 -3.35
Cell Periphery 9.97 8.58 7.76 -8.86 -2.80 -0.77 7.09 -6.70 -5.62 -8.79 8.19 10.23 1.47 -7.33 -9.76
Cytoplasm 11.13 12.38 -4.18 -13.93 -14.95 6.83 5.84 -13.55 -17.49 -16.97 12.69 12.79 -12.96 -22.23 -22.27
Cytoplasmic Foci 9.85 18.54 11.77 2.61 -7.33 10.34 13.40 8.35 -0.69 -3.14 14.04 21.98 14.01 1.17 -6.75
Eisosomes 13.69 11.41 11.82 -9.31 0.98 5.43 11.51 -5.81 -9.51 -12.90 14.54 15.09 6.35 -11.24 -12.19
Endoplasmic Reticulum 2.24 -2.98 -4.75 -7.54 -2.17 -2.41 -6.61 -4.62 -3.46 -1.79 1.05 -4.68 -6.95 -8.19 -3.90
Endosome -20.28 -9.26 10.61 33.69 19.50 -9.66 -3.23 21.70 32.10 25.37 -20.03 -9.10 23.82 46.78 33.20
Golgi -1.07 9.70 11.62 14.09 5.06 -6.35 9.06 10.43 13.95 2.72 -5.34 13.21 15.77 19.85 5.04
Lipid Particles 12.77 13.46 14.28 2.34 0.44 2.40 13.54 9.74 7.49 -4.75 9.90 19.29 17.15 8.15 -3.95
Mitochondria 4.19 9.03 9.97 7.36 1.74 -2.47 5.75 1.99 4.15 -2.32 0.86 10.55 8.04 7.57 -1.54
Mitotic Spindle -8.89 -8.94 -11.38 -6.39 -1.41 -3.37 -13.35 -6.57 -5.27 5.40 -9.12 -16.15 -12.92 -8.54 2.56
None 1.89 1.95 0.95 -2.39 -2.73 2.86 2.68 -2.51 -3.27 -3.23 2.85 2.88 -1.50 -3.84 -3.86
Nuclear Periphery 1.99 -2.63 -4.76 -10.45 -2.22 0.70 -5.87 -3.75 -3.91 -1.21 2.12 -5.23 -6.54 -8.73 -2.69
Nuclear Periphery Foci -5.26 -8.21 -7.91 -6.86 1.60 -1.86 -7.78 -4.04 -0.59 6.27 -3.21 -11.15 -8.50 -6.15 4.27
Nucleolus 2.23 -7.13 -3.20 -4.55 5.83 1.21 -4.91 -5.27 -5.98 -1.30 2.16 -8.70 -5.94 -7.32 3.69
Nucleus 10.13 -1.42 -1.65 -10.56 0.13 5.40 2.69 -14.34 -15.87 -15.19 11.26 0.84 -13.05 -18.45 -13.02
Peroxisomes 3.18 -4.18 -0.55 -3.33 3.46 4.90 1.28 5.78 1.39 4.50 5.83 -1.75 3.14 -1.91 4.49
Vacuole 0.04 -9.23 -24.56 -24.79 -14.16 0.08 -11.57 -18.39 -18.35 -10.29 -0.07 -14.51 -30.70 -30.68 -18.52
Vacuole Periphery -2.31 0.25 6.95 6.30 4.87 -6.24 2.16 0.42 5.51 -0.84 -5.75 2.05 4.75 8.60 2.77
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to endosomes
Localization
Cell Percentages endosome (20%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Snn1

Snn1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Snn1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available