Standard name
Human Ortholog
Description Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton; may control nonselective autophagy and mitophagy through trafficking of Atg9p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.96 0.99 0.99 0.97 0.98 0.92 0.94 0.86 – 0.79 0.68 1.0 0.97 0.96 – 0.94 0.96 0.74 0.79 0.6 0.84 0.87 0.84
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 0.06 0 0.06 0 0.09 0.16 0.16 0.3 – 0.39 0.43 0 0 0 – 0 0 0.15 0.09 0.22 0.06 0 0.05
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 2 3 5 1 3 2
Bud 1 1 1 2 1 1 10 2 4 – 7 5 0 0 11 – 0 1 0 1 0 0 0 3
Bud Neck 4 1 1 3 11 4 9 5 3 – 7 5 0 0 0 – 4 6 0 1 0 0 1 0
Bud Site 0 0 0 0 0 0 1 1 1 – 0 3 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 1 3 1 3 3 1 3 2 – 0 2 0 1 0 – 3 3 2 2 4 0 1 1
Cytoplasm 212 250 195 246 311 384 392 461 232 – 215 240 150 296 295 – 244 388 166 200 103 135 234 245
Endoplasmic Reticulum 1 1 0 0 1 0 0 0 0 – 0 1 0 10 9 – 9 28 1 0 2 0 2 5
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 5 5 3 1 0 0 0 1
Golgi 1 1 0 0 1 0 0 0 0 – 0 0 0 0 0 – 1 0 1 0 1 1 0 0
Mitochondria 3 15 4 14 9 36 68 76 82 – 105 153 4 1 5 – 5 9 34 24 38 9 9 15
Nucleus 1 0 0 1 0 0 1 3 0 – 0 2 0 1 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 1 0 0 – 0 3 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 1 0 2 2 – 1 1 0 0 0 – 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 1 0 0 0 – 1 0 0 0 0 0 0 0
SpindlePole 1 1 0 1 0 0 6 8 4 – 5 12 0 0 1 – 3 2 3 2 1 1 1 4
Vac/Vac Membrane 1 2 0 0 0 0 2 0 1 – 0 0 0 0 0 – 4 7 1 7 2 0 5 6
Unique Cell Count 218 260 196 249 322 393 425 489 269 271 353 150 306 306 260 404 225 254 172 161 268 292
Labelled Cell Count 226 273 204 268 337 429 491 561 331 340 428 154 309 321 279 450 225 254 172 161 268 292


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.9 3.1 2.9 2.6 2.9 2.6 2.5 2.7 2.2 – 2.3 2.1 3.9 4.2 3.7 4.7 5.1 5.1 3.9 3.4 4.4
Std Deviation (1e-4) 0.7 0.6 0.9 0.9 0.8 0.8 1.2 1.1 1.1 – 0.9 1.1 1.3 1.8 1.7 1.7 2.1 1.6 1.3 1.1 2.0
Intensity Change (Log2) – – – -0.12 0.01 -0.13 -0.17 -0.1 -0.35 – -0.34 -0.43 0.44 0.56 0.37 0.73 0.84 0.83 0.44 0.24 0.61

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.2077 -0.462 -0.4974 -0.6731 -0.9278 -0.4857 1.3716 0.7348 0.5687 0.5939 0.8906 0.5678 -0.2438 0.2158 -0.2484 -0.0151 -0.2876 0.0507
Actin 0.062 0.0008 0.0046 0.0027 0.0009 0.0016 0.0832 0.0002 0.0148 0.0125 0.0297 0.0101 0.0107 0.0001 0.0001 0.0001 0 0.0001
Bud 0.0011 0.0008 0.0008 0.0084 0 0.0006 0.0037 0.0001 0.0022 0.0002 0.0016 0.0011 0.001 0.0001 0 0 0 0
Bud Neck 0.0115 0.0002 0.0032 0.004 0 0.0038 0.0091 0 0.0003 0.0002 0.0011 0.0015 0.0008 0.0002 0 0 0 0
Bud Periphery 0.0021 0.0013 0.0018 0.0255 0.0001 0.0023 0.0081 0.0002 0.0097 0.0003 0.0043 0.0046 0.0034 0.0002 0.0001 0 0 0
Bud Site 0.0124 0.003 0.0123 0.0033 0 0.0044 0.0322 0.0002 0.0018 0.0007 0.004 0.0006 0.0008 0.0003 0 0 0 0
Cell Periphery 0.0005 0.0002 0.0007 0.0009 0 0.0007 0.0012 0.0001 0.0003 0.0001 0.0003 0.0001 0.0009 0.0005 0.0001 0 0 0
Cytoplasm 0.0125 0.038 0.0189 0.0361 0.0056 0.0425 0.0355 0.0584 0.0281 0.0284 0.0721 0.0847 0.025 0.016 0.0147 0.0103 0.0346 0.0199
Cytoplasmic Foci 0.0323 0.0368 0.0072 0.0165 0.0012 0.0174 0.0474 0.0054 0.0108 0.0054 0.007 0.0137 0.0034 0.0043 0.0019 0.0022 0.007 0.0033
Eisosomes 0.0007 0.0002 0.0003 0.0003 0.0004 0.0002 0.001 0.0001 0.0002 0.0002 0.0004 0.0002 0.0007 0.0003 0.0003 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.003 0.0008 0.0005 0.0011 0 0.0002 0.0073 0.0005 0.0011 0.0019 0.0008 0.0016 0.0027 0.0004 0.0003 0.0002 0.0008 0.0003
Endosome 0.0415 0.003 0.0026 0.0016 0 0.0003 0.0401 0.0048 0.0123 0.0218 0.0273 0.0092 0.0054 0.0038 0.0005 0.0007 0.0132 0.0035
Golgi 0.0308 0.0005 0.0029 0.0005 0 0.0001 0.0142 0.0002 0.0039 0.0078 0.0106 0.0069 0.0005 0.0001 0 0 0.0001 0
Lipid Particles 0.0367 0.0017 0.0017 0.0012 0.0001 0.0007 0.0348 0.0005 0.0034 0.008 0.0247 0.0106 0.0028 0.0006 0.001 0.0004 0.0002 0.0003
Mitochondria 0.0165 0.0011 0.0052 0.0039 0.0001 0.0002 0.0166 0.0002 0.0192 0.0044 0.0297 0.0083 0.0007 0.0003 0.0001 0.0002 0.0001 0.0001
None 0.6882 0.9037 0.9301 0.8858 0.9911 0.9144 0.6037 0.923 0.8588 0.9014 0.7361 0.8195 0.9103 0.918 0.9794 0.9843 0.9402 0.9681
Nuclear Periphery 0.0052 0.0003 0.0003 0.0005 0 0.0002 0.0166 0.0003 0.0013 0.0028 0.0011 0.0069 0.0045 0.0002 0.0001 0.0002 0.0002 0.0001
Nucleolus 0.0017 0.0004 0.0024 0.0013 0 0.0003 0.0011 0.0002 0.0007 0.0001 0.0006 0.0012 0.0023 0.0006 0.0001 0.0001 0 0.0001
Nucleus 0.002 0.0008 0.0006 0.0011 0 0.0008 0.0021 0.0002 0.0016 0.0004 0.0008 0.0029 0.0023 0.0014 0.0001 0.0001 0.0001 0.0003
Peroxisomes 0.0293 0.0036 0.0013 0.0013 0.0002 0.0003 0.0138 0.0002 0.0142 0.001 0.0282 0.0036 0.0003 0.0001 0.0001 0.0001 0 0
Punctate Nuclear 0.006 0.0023 0.0014 0.0011 0.0001 0.0087 0.0193 0.0006 0.0018 0.0011 0.0011 0.0043 0.0107 0.0002 0.0003 0.0002 0.0001 0.0001
Vacuole 0.0028 0.0006 0.001 0.0024 0 0.0003 0.0063 0.0042 0.0125 0.0007 0.0113 0.006 0.009 0.051 0.0007 0.0007 0.0027 0.0033
Vacuole Periphery 0.0014 0.0001 0.0002 0.0005 0 0 0.0027 0.0003 0.001 0.0006 0.0073 0.0023 0.0017 0.0013 0 0.0001 0.0006 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 20.1653 16.0236 16.692 25.8125 18.7709 20.6709 27.5736 26.1806 22.7768 28.1858
Translational Efficiency 0.8187 0.8527 0.8884 0.5358 0.8148 0.7103 0.5448 0.4771 0.6144 0.5484

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
163 1276 1440 1209 1572 1401 185 104 1735 2677 1625 1313

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 639.85 688.52 812.14 782.02 616.86 684.51 913.61 819.83 619.02 686.42 823.69 785.01
Standard Deviation 86.48 98.08 87.72 104.36 71.33 88.48 84.04 88.94 73.20 93.20 93.06 103.72
Intensity Change Log 2 — 0.105765 0.343995 0.289472 — 0.150129 0.566635 0.410382 — 0.127711 0.457572 0.350087

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000061 0.000990 0.000191 0.000959 0.000085 0.000459 0.000342 0.000280 0.000083 0.000712 0.000208 0.000905
Bud Neck 0.038541 0.052679 0.002723 0.006179 0.010574 0.046461 0.001706 0.003868 0.013202 0.049425 0.002608 0.005996
Bud Site 0.005691 0.019123 0.002070 0.019014 0.002034 0.016971 0.001548 0.002857 0.002378 0.017996 0.002011 0.017734
Cell Periphery 0.000303 0.000175 0.000119 0.000172 0.000098 0.000444 0.000208 0.000152 0.000117 0.000316 0.000129 0.000170
Cytoplasm 0.337473 0.302123 0.195615 0.466482 0.503875 0.323937 0.155819 0.393502 0.488242 0.313539 0.191084 0.460701
Cytoplasmic Foci 0.284611 0.302870 0.005448 0.029090 0.188038 0.260294 0.012788 0.021517 0.197111 0.280588 0.006284 0.028490
Eisosomes 0.000332 0.000215 0.000032 0.000054 0.000111 0.000245 0.000105 0.000085 0.000132 0.000231 0.000040 0.000057
Endoplasmic Reticulum 0.001473 0.000697 0.003048 0.001450 0.000552 0.000829 0.005843 0.005118 0.000639 0.000766 0.003366 0.001740
Endosome 0.020154 0.036842 0.001527 0.012848 0.006243 0.032130 0.004319 0.002805 0.007550 0.034376 0.001845 0.012052
Golgi 0.001430 0.012051 0.000044 0.004427 0.001473 0.007818 0.000383 0.000051 0.001469 0.009836 0.000083 0.004080
Lipid Particles 0.020018 0.014228 0.001188 0.001703 0.008966 0.017302 0.003917 0.002330 0.010004 0.015837 0.001499 0.001753
Mitochondria 0.013686 0.026708 0.000469 0.003456 0.004761 0.023710 0.011523 0.000170 0.005599 0.025139 0.001728 0.003195
Mitotic Spindle 0.000545 0.005009 0.001807 0.056587 0.001409 0.010435 0.000254 0.000325 0.001328 0.007849 0.001631 0.052131
None 0.001152 0.002910 0.004002 0.007023 0.004251 0.003234 0.003064 0.004686 0.003960 0.003080 0.003895 0.006838
Nuclear Periphery 0.000604 0.000558 0.001978 0.001705 0.000686 0.001291 0.002212 0.001454 0.000678 0.000942 0.002005 0.001685
Nuclear Periphery Foci 0.000614 0.000317 0.000621 0.000921 0.000279 0.000454 0.001948 0.001599 0.000310 0.000389 0.000772 0.000975
Nucleolus 0.001690 0.002925 0.000586 0.001035 0.001417 0.002603 0.000786 0.000258 0.001443 0.002756 0.000609 0.000974
Nucleus 0.181333 0.105858 0.755416 0.261028 0.230452 0.144883 0.687328 0.359321 0.225838 0.126282 0.747664 0.268814
Peroxisomes 0.008920 0.037096 0.000553 0.003107 0.004052 0.022934 0.000346 0.000275 0.004509 0.029684 0.000530 0.002883
Vacuole 0.078622 0.072931 0.022442 0.116048 0.030049 0.080092 0.104649 0.199247 0.034613 0.076679 0.031801 0.122638
Vacuole Periphery 0.002747 0.003693 0.000119 0.006713 0.000594 0.003474 0.000912 0.000099 0.000797 0.003579 0.000209 0.006189

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.56 -6.13 -3.02 1.23 -1.71 -5.71 -8.66 -5.14 0.22 0.04 -3.60 -8.08 -3.12 0.96 -1.65
Bud Neck -1.51 4.03 3.74 14.36 -4.50 -12.58 6.71 1.62 12.06 -2.19 -15.01 7.72 5.35 20.36 -5.02
Bud Site -5.34 2.02 -2.52 3.17 -5.67 -8.20 -1.16 -4.50 5.77 -3.78 -11.64 -0.06 -5.95 3.71 -5.84
Cell Periphery 3.21 4.41 4.78 4.20 1.17 -3.04 -6.57 -3.81 2.39 1.81 -3.28 -1.95 -0.03 3.27 1.80
Cytoplasm 1.91 8.42 -0.23 -3.70 -16.19 18.71 25.04 9.28 2.48 -4.12 21.42 37.62 15.15 -2.44 -16.90
Cytoplasmic Foci -0.91 14.71 14.03 42.88 -8.94 -9.18 33.70 27.22 33.83 -2.19 -12.59 39.54 36.13 57.03 -8.96
Eisosomes 3.96 11.46 10.37 8.93 -8.90 -7.71 -2.40 -1.37 6.07 0.87 -7.28 10.54 7.84 13.73 -6.31
Endoplasmic Reticulum 1.16 -3.99 -1.86 -14.93 6.43 -2.30 -11.29 -6.18 -5.93 0.45 -1.21 -18.82 -14.34 -14.71 6.41
Endosome -4.39 5.82 4.55 14.20 -3.64 -13.90 1.65 3.84 15.83 2.18 -18.21 8.47 2.33 18.44 -3.37
Golgi -8.65 3.84 0.20 8.39 -2.56 -6.67 4.46 5.54 8.48 1.03 -10.90 6.11 0.35 9.70 -2.53
Lipid Particles 1.02 3.32 3.29 10.47 -1.42 -5.08 5.09 7.13 9.71 2.34 -4.47 9.39 9.43 14.87 0.16
Mitochondria -2.26 2.56 2.35 11.04 -3.64 -8.62 -0.06 6.24 11.38 1.02 -11.23 4.65 4.75 15.26 -0.76
Mitotic Spindle -3.90 -1.36 -8.04 -6.82 -7.74 -4.51 1.70 -0.78 3.17 -1.44 -5.39 -0.38 -7.88 -5.95 -7.79
None -2.70 -4.60 -6.46 -2.83 -2.95 1.32 3.42 1.27 0.20 -1.16 1.17 0.92 -1.94 -3.24 -3.16
Nuclear Periphery 0.28 -13.25 -15.70 -19.15 -6.01 -2.39 -10.20 -7.34 -4.04 0.51 -1.70 -15.09 -16.83 -13.19 -5.70
Nuclear Periphery Foci 0.94 -0.50 -0.71 -7.10 -0.58 -0.99 -6.00 -6.57 -5.55 -0.25 -0.71 -6.61 -8.53 -5.82 -0.18
Nucleolus -1.60 2.05 1.74 4.58 -1.86 -3.28 3.87 6.09 7.25 3.59 -4.06 4.73 3.78 7.07 -1.54
Nucleus 5.21 -37.78 -10.03 -25.58 40.29 11.95 -16.83 -3.27 -6.67 9.07 16.92 -63.84 -12.48 -25.44 40.39
Peroxisomes -8.36 3.63 3.31 14.46 -1.44 -11.48 9.96 10.09 14.15 0.87 -16.78 9.28 6.25 19.17 -1.45
Vacuole 0.29 4.32 -11.79 -18.22 -24.48 -13.77 -9.14 -11.52 -9.71 -5.13 -14.84 -4.94 -26.75 -20.38 -23.13
Vacuole Periphery -0.86 3.31 0.64 1.83 -3.03 -6.53 0.30 7.76 7.68 1.22 -8.42 6.20 -1.92 2.21 -2.96
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton; may control nonselective autophagy and mitophagy through trafficking of Atg9p
Localization
Cell Percentages cytoplasm (15%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Pik1

Pik1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pik1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available