Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L18B; homologous to mammalian ribosomal protein L18, no bacterial homolog; RPL18B has a paralog, RPL18A, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0.05 0.05 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0.05 0.05 0.08 0.06 0.07 0.08 0 0 0 0 0 0.06 0 0 0 0 0 0
Cytoplasm 0.99 0.98 0.97 0.98 0.95 0.87 0.8 0.73 0.68 0.68 0.69 0.6 0.99 0.98 0.98 0.98 0.98 0.98 0.97 0.94 0.95 0.94 0.95 0.92
Endoplasmic Reticulum 0 0 0 0 0 0.11 0.15 0.23 0.24 0.2 0.17 0.27 0 0 0 0 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 5 13 11 21 23 18 25 0 0 0 0 0 0 0 0 0 0 0 0
Bud 1 2 1 0 0 1 2 1 0 3 4 1 0 0 1 0 0 0 1 0 2 0 2 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 3 6 11 9 25 26 32 27 24 34 2 1 4 8 8 12 0 0 0 0 0 0
Cytoplasm 339 99 150 277 376 288 387 359 271 312 249 265 164 346 377 267 211 184 326 93 140 143 305 306
Endoplasmic Reticulum 2 1 1 4 17 35 71 114 95 93 63 118 1 10 7 12 10 6 4 0 2 2 7 13
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 1 0 5 5 5 5 7 14 11 12 0 0 1 1 1 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 3 2 14 12 17 15 0 0 0 0 0 0 0 0 0 0 1 0
Nucleus 0 0 0 1 0 1 1 1 1 1 0 1 0 0 0 0 0 0 0 0 0 1 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 1 2 1 2 4 3 2 19 6 21 0 0 3 2 1 1 0 0 0 1 1 2
Unique Cell Count 341 101 154 283 396 332 481 495 400 457 360 440 165 352 384 272 215 188 335 99 147 153 323 332
Labelled Cell Count 343 102 157 290 410 346 511 522 446 504 393 494 167 357 393 290 231 203 335 99 147 153 323 332


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 70.5 91.1 68.1 67.5 53.3 39.7 34.5 34.0 28.8 27.7 25.1 24.6 82.5 79.0 76.3 109.4 130.7 132.7 76.2 81.2 86.9
Std Deviation (1e-4) 13.8 22.2 15.5 15.0 9.9 8.8 8.0 7.0 6.4 6.2 6.1 5.2 19.4 18.5 18.3 27.9 31.8 30.6 21.6 22.7 24.5
Intensity Change (Log2) – – – -0.01 -0.36 -0.78 -0.98 -1.0 -1.24 -1.3 -1.44 -1.47 0.28 0.21 0.16 0.68 0.94 0.96 0.16 0.25 0.35

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700050100150WT3HU80HU120HU160050100150WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100150WT1AF100AF140AF180050100150
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 2.9 2.8 2.8 3.0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 1.7 1.7 2.6 2.0 2.2 2.6 0 0 0 0 0 2.0
Cytoplasm 0.3 -1.3 -3.7 -5.1 -6.6 -7.3 -7.3 -7.0 -8.7 1.4 0.7 0.6 0.5 0.5 0.3
Endoplasmic Reticulum 0 2.2 3.9 4.8 6.4 6.4 5.9 5.3 7.0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 2.7 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 2.1 0 2.3 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 57.7442 75.8009 69.3443 58.8915 63.5618 66.8167 55.5187 84.0174 72.3325 65.1116 60.4982 64.0273 62.1331 79.0967 75.8978 69.1106 63.252 66.8636
Actin 0.0007 0.0001 0.0001 0.0136 0.0001 0.0002 0.0118 0.0001 0.01 0.0111 0.0436 0.0164 0.0013 0.0011 0.0049 0.0003 0.0044 0.0305
Bud 0.0004 0.0001 0.0001 0.0008 0.0002 0.0001 0.0004 0.0001 0.0005 0.0013 0.0005 0.0004 0.0005 0.0001 0.0002 0.0006 0.0002 0.0003
Bud Neck 0.0004 0.0002 0.0003 0.0006 0.0009 0.0007 0.0011 0.0001 0.001 0.0013 0.0014 0.001 0.0002 0.0002 0.0002 0.0003 0.0009 0.0004
Bud Periphery 0.0006 0.0001 0.0001 0.001 0.0002 0.0002 0.0005 0 0.0003 0.0016 0.0007 0.0002 0.0006 0 0.0002 0.0005 0.0003 0.0002
Bud Site 0.0002 0.0001 0 0.0007 0.0001 0 0.0024 0.0001 0.0006 0.006 0.0012 0.0004 0.0002 0.0001 0.0003 0.0009 0.0021 0.0003
Cell Periphery 0.0042 0.0031 0.0014 0.0027 0.0034 0.002 0.0013 0.0002 0.0003 0.0002 0.0001 0.0001 0.0013 0.0013 0.0015 0.003 0.0002 0
Cytoplasm 0.8802 0.9632 0.9388 0.8915 0.9311 0.9248 0.8257 0.9902 0.8893 0.9022 0.7253 0.9233 0.8862 0.9732 0.9482 0.893 0.8589 0.9283
Cytoplasmic Foci 0.005 0.0006 0.0011 0.0016 0.0011 0.0042 0.0152 0.0006 0.0123 0.0076 0.0085 0.0067 0.0027 0.0006 0.0054 0.0033 0.016 0.0027
Eisosomes 0.0001 0 0 0.0003 0 0 0.0001 0 0.0002 0.0001 0.0004 0.0001 0 0 0.0001 0.0001 0.0002 0.0002
Endoplasmic Reticulum 0.0456 0.0185 0.0246 0.012 0.0069 0.0381 0.0195 0.0036 0.014 0.0094 0.0327 0.0083 0.0303 0.0151 0.0067 0.017 0.0066 0.0086
Endosome 0.0047 0.0009 0.0021 0.0066 0.0055 0.0033 0.0172 0.0008 0.005 0.0079 0.0115 0.0068 0.0058 0.0006 0.0037 0.0055 0.0176 0.0066
Golgi 0.0006 0.0001 0.0001 0.0014 0.0001 0.0006 0.0043 0.0001 0.0024 0.0036 0.0085 0.0019 0.0005 0.0002 0.003 0.0003 0.005 0.0017
Lipid Particles 0.0015 0.0013 0.0008 0.0008 0.0008 0.0003 0.0142 0.0001 0.005 0.0037 0.014 0.003 0.0009 0.0005 0.0021 0.0024 0.0249 0.0018
Mitochondria 0.0028 0.0004 0.0002 0.0046 0.0004 0.0018 0.0036 0 0.0079 0.0039 0.0674 0.0007 0.0024 0.0001 0.0024 0.0049 0.0057 0.0016
None 0.003 0.0001 0.0003 0.0015 0.0003 0.0012 0.0044 0.0001 0.0019 0.0011 0.0032 0.0015 0.0019 0.0001 0.0013 0.0016 0.0029 0.0003
Nuclear Periphery 0.0078 0.0016 0.004 0.0077 0.0058 0.0054 0.0187 0.001 0.0074 0.0033 0.0492 0.0075 0.0204 0.0021 0.0039 0.0065 0.0221 0.0065
Nucleolus 0.0019 0 0.0027 0.0013 0.0002 0.0021 0.0041 0 0.0012 0.0004 0.0005 0.0003 0.0008 0.0001 0.0031 0.0015 0.0014 0
Nucleus 0.005 0.001 0.0032 0.0062 0.0062 0.0021 0.0091 0.0007 0.0032 0.0021 0.0015 0.0029 0.0057 0.0007 0.0023 0.0033 0.0023 0.0021
Peroxisomes 0.0005 0 0 0.0002 0 0.0001 0.007 0 0.0131 0.0166 0.0131 0.0016 0.0004 0 0.0008 0.0002 0.009 0.0023
Punctate Nuclear 0.0033 0 0.0001 0.0004 0 0.0002 0.0155 0 0.0014 0.0022 0.0061 0.0118 0.0007 0 0.0003 0.0001 0.0051 0.0001
Vacuole 0.0267 0.008 0.0175 0.0396 0.0294 0.0113 0.0191 0.002 0.016 0.012 0.0074 0.0042 0.0274 0.0037 0.0075 0.043 0.01 0.0035
Vacuole Periphery 0.0048 0.0004 0.0025 0.0051 0.0072 0.0013 0.0047 0.0002 0.0069 0.0026 0.0034 0.0011 0.0096 0.0003 0.0015 0.0116 0.0041 0.0018

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 941.1391 1114.7282 1458.6486 1000.9419 1290.356 973.0532 944.88 866.9053 1108.5895 813.2231
Translational Efficiency 1.0269 1.0542 0.8869 1.3469 0.9628 0.9178 1.1151 1.2188 0.9852 1.2643

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2597 1118 2090 116 2256 1952 440 1221 4853 3070 2530 1337

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 5321.77 6112.24 7772.70 7268.10 4689.40 5883.66 7691.31 6429.59 5027.80 5966.90 7758.55 6502.34
Standard Deviation 1109.68 1315.88 1440.33 1868.91 977.10 1292.97 1449.49 2216.95 1096.47 1306.00 1442.25 2201.64
Intensity Change Log 2 — 0.199795 0.546510 0.449672 — 0.327311 0.713826 0.455323 — 0.260931 0.627304 0.452322

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000012 0.000097 0.000052 0.000138 0.000022 0.000053 0.000136 0.000260 0.000017 0.000069 0.000066 0.000250
Bud Neck 0.000043 0.000639 0.000644 0.004453 0.000160 0.000280 0.005853 0.002623 0.000098 0.000411 0.001550 0.002782
Bud Site 0.000604 0.002995 0.001352 0.003870 0.000845 0.001103 0.003393 0.011545 0.000716 0.001792 0.001707 0.010879
Cell Periphery 0.001448 0.013573 0.013314 0.054332 0.003252 0.004082 0.019759 0.014863 0.002286 0.007539 0.014435 0.018287
Cytoplasm 0.940344 0.784171 0.780609 0.352355 0.869581 0.887103 0.438578 0.718761 0.907448 0.849618 0.721126 0.686971
Cytoplasmic Foci 0.005164 0.010919 0.004197 0.011919 0.005689 0.007387 0.018616 0.014399 0.005408 0.008673 0.006705 0.014183
Eisosomes 0.000000 0.000002 0.000001 0.000007 0.000000 0.000001 0.000005 0.000004 0.000000 0.000001 0.000002 0.000004
Endoplasmic Reticulum 0.000390 0.000449 0.000606 0.000198 0.000611 0.000227 0.000241 0.000212 0.000493 0.000308 0.000542 0.000211
Endosome 0.000162 0.000560 0.000324 0.000682 0.000362 0.000300 0.000943 0.002012 0.000255 0.000395 0.000432 0.001896
Golgi 0.013858 0.047049 0.022434 0.022139 0.030823 0.024734 0.039313 0.011447 0.021744 0.032860 0.025369 0.012374
Lipid Particles 0.001428 0.011152 0.011045 0.041589 0.004716 0.004079 0.021775 0.013651 0.002957 0.006655 0.012911 0.016075
Mitochondria 0.000127 0.000156 0.000117 0.000063 0.000109 0.000115 0.000164 0.000732 0.000119 0.000130 0.000125 0.000674
Mitotic Spindle 0.000247 0.001106 0.000572 0.000949 0.000834 0.000850 0.001986 0.007701 0.000520 0.000943 0.000818 0.007115
None 0.001717 0.002764 0.001285 0.001062 0.001836 0.002464 0.001388 0.003154 0.001772 0.002573 0.001303 0.002973
Nuclear Periphery 0.000113 0.000855 0.000823 0.001661 0.000285 0.000312 0.002994 0.000594 0.000193 0.000510 0.001201 0.000687
Nuclear Periphery Foci 0.003945 0.016546 0.011855 0.021046 0.010707 0.008235 0.024210 0.007131 0.007088 0.011262 0.014004 0.008338
Nucleolus 0.000018 0.000090 0.000055 0.000203 0.000025 0.000078 0.000202 0.000363 0.000021 0.000082 0.000081 0.000349
Nucleus 0.002834 0.012456 0.011326 0.027270 0.003735 0.010987 0.035992 0.025513 0.003253 0.011522 0.015616 0.025665
Peroxisomes 0.000008 0.000019 0.000012 0.000034 0.000007 0.000009 0.000014 0.000116 0.000007 0.000013 0.000012 0.000109
Vacuole 0.009788 0.056887 0.104076 0.424589 0.027935 0.026982 0.332348 0.150376 0.018224 0.037872 0.143776 0.174167
Vacuole Periphery 0.017750 0.037515 0.035300 0.031441 0.038464 0.020617 0.052090 0.014545 0.027379 0.026771 0.038220 0.016011

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.22 -5.70 -6.62 -1.91 -4.43 -2.65 -8.39 -6.77 -5.55 -1.90 -4.32 -8.43 -7.34 -5.26 -5.22
Bud Neck -7.97 -7.35 -4.30 -3.92 -3.82 -2.36 -10.84 -10.43 -10.14 5.27 -8.23 -12.03 -11.46 -10.56 -5.30
Bud Site -4.44 -6.15 -4.72 -0.92 -3.56 -1.88 -6.17 -8.58 -8.39 -5.87 -5.06 -7.89 -8.91 -7.84 -7.93
Cell Periphery -12.80 -14.27 -7.55 -5.38 -5.45 -2.09 -9.16 -8.95 -7.99 2.82 -12.22 -15.87 -12.06 -6.80 -1.03
Cytoplasm 18.22 24.68 21.93 15.30 15.17 -2.41 28.11 19.47 21.05 -14.81 12.04 28.48 28.55 20.41 5.32
Cytoplasmic Foci -5.86 1.02 -3.29 -1.80 -3.42 -2.85 -7.32 -8.37 -7.43 -0.28 -6.23 -4.52 -8.95 -7.12 -7.56
Eisosomes -8.17 -9.02 -5.83 -4.72 -4.94 -1.94 -10.61 -8.07 -7.01 3.98 -6.30 -12.77 -9.68 -7.57 -4.49
Endoplasmic Reticulum -0.76 -2.32 2.82 4.00 5.28 5.06 5.09 5.65 1.06 1.28 3.44 -0.60 5.88 3.56 5.89
Endosome -7.68 -8.51 -3.32 -1.18 -2.39 1.54 -8.00 -3.57 -3.69 -1.82 -5.21 -8.54 -3.95 -3.56 -3.39
Golgi -13.03 -7.11 -2.18 7.73 1.05 3.20 -1.54 13.29 9.58 11.23 -7.72 -2.65 9.73 15.35 12.53
Lipid Particles -10.15 -13.69 -8.10 -5.91 -5.98 0.84 -9.26 -7.84 -8.58 3.42 -7.86 -14.39 -11.69 -8.18 -2.84
Mitochondria -0.86 -0.28 1.45 2.03 2.31 -0.41 -2.80 -4.16 -4.10 -3.08 -0.74 -1.85 -4.08 -3.96 -3.82
Mitotic Spindle -5.55 -5.80 -2.26 -0.82 -1.61 0.42 -1.71 -5.20 -5.34 -4.23 -2.10 -1.71 -5.52 -5.32 -5.32
None -2.04 1.98 1.96 3.16 0.84 -2.02 1.56 -2.63 -1.39 -4.12 -3.07 2.68 -2.86 -0.80 -4.37
Nuclear Periphery -8.77 -12.74 -7.30 -4.01 -3.99 -1.08 -10.37 -4.97 -4.51 8.42 -8.79 -15.21 -7.62 -3.48 4.27
Nuclear Periphery Foci -10.38 -11.02 -4.70 -1.16 -2.35 2.78 -6.98 2.95 0.52 8.31 -6.59 -9.90 -2.50 2.53 5.40
Nucleolus -2.14 -10.97 -5.12 -2.94 -4.23 -1.53 -10.81 -7.39 -5.27 -2.43 -2.43 -15.06 -7.89 -5.81 -6.26
Nucleus -9.35 -11.58 -5.35 -3.76 -3.66 -9.93 -10.60 -15.71 -11.31 3.08 -13.97 -15.00 -16.90 -11.86 -7.13
Peroxisomes -1.72 -2.79 -2.79 -1.01 -2.40 -1.01 -5.28 -3.95 -3.84 -3.55 -1.94 -4.56 -4.03 -3.71 -3.81
Vacuole -13.25 -24.59 -15.91 -13.87 -11.80 0.16 -22.76 -21.66 -21.45 11.83 -10.34 -29.24 -26.51 -22.55 -4.59
Vacuole Periphery -7.20 -9.30 -1.88 1.99 1.74 7.53 -1.80 11.67 4.78 9.93 0.38 -5.51 8.93 7.98 13.56
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L18B; homologous to mammalian ribosomal protein L18, no bacterial homolog; RPL18B has a paralog, RPL18A, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Rpl18b

Rpl18b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl18b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available