ORF
Human Ortholog
Description Potential noncatalytic subunit for phospholipid translocase Dnf3p; YNR048W has a paralog, CDC50, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.08 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0.17 0.1 0.11 0.09 0.08 0.17 0.1 0.11 0.14
Bud 0 0 0 0 0 0.05 0.06 0 0.06 0.05 0.05 0 0 0 0 0 0 0 0.05 0.05 0 0.09 0.05 0.09
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.1 0.08 0.08
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0 0 0 0 0 0
Cytoplasm 0.78 0.85 0.79 0.85 0.87 0.78 0.7 0.61 0.64 0.65 0.52 0.58 0.95 0.98 0.95 0.71 0.74 0.69 0.37 0.53 0.29 0.43 0.49 0.49
Endoplasmic Reticulum 0 0.06 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0.05 0 0.06 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.06 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.2 0 0.09 0.09 0 0.29 0.4 0.45 0.48 0.43 0.61 0.57 0 0 0 0 0 0 0.22 0.12 0.24 0.12 0.12 0.07
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.08 0.07 0 0.05 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 17 13 6 4 1 3 1 4 4 1 1 3 0 0 31 25 24 12 18 53 20 23 32
Bud 0 8 9 7 5 15 25 12 17 14 12 11 1 0 2 3 8 8 6 11 12 17 11 22
Bud Neck 0 0 1 1 0 0 4 0 0 0 1 1 1 1 1 0 3 0 5 8 16 18 17 18
Bud Site 0 0 1 0 2 8 2 2 1 5 1 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 5 3 3 1 5 4 0 2 2 2 1 1 1 8 15 12 0 2 6 2 4 5
Cytoplasm 96 173 205 141 156 255 293 189 192 186 122 148 261 214 282 130 187 152 47 127 93 82 108 116
Endoplasmic Reticulum 5 12 14 4 1 3 4 1 9 4 4 5 3 5 2 7 13 12 5 7 19 1 2 5
Endosome 1 2 5 1 5 4 1 4 1 0 2 0 3 1 4 3 8 17 8 10 13 5 5 4
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 5 1 1 1
Mitochondria 25 3 23 15 7 96 168 140 143 121 144 143 0 0 0 7 10 4 28 27 77 22 26 16
Nucleus 0 0 0 0 1 2 2 0 0 1 2 0 0 0 0 3 2 1 0 0 0 1 1 1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 1 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 1 1 3 1 0 2 0 0 0 0 1 0 6 0 0 3 0 0 1 0 0 0
SpindlePole 0 2 3 4 5 5 6 9 3 2 1 2 4 0 3 7 9 7 0 2 2 4 2 1
Vac/Vac Membrane 0 1 1 0 3 0 2 6 3 2 4 1 1 2 4 7 7 12 9 16 11 10 10 10
Unique Cell Count 123 204 259 166 179 326 420 309 298 284 235 253 274 218 297 182 253 219 128 239 319 193 219 238
Labelled Cell Count 130 219 282 183 195 392 515 370 373 341 298 319 279 224 305 206 287 253 128 239 319 193 219 238


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.9 4.7 4.2 4.0 6.2 3.7 3.5 3.4 3.4 3.3 3.0 3.0 5.5 5.6 5.4 7.4 7.1 6.6 5.5 5.5 5.9
Std Deviation (1e-4) 0.7 1.0 0.9 1.5 6.6 1.6 1.4 1.3 1.3 0.8 1.1 0.8 1.1 1.1 1.5 1.0 1.3 1.1 1.3 1.6 1.7
Intensity Change (Log2) – – – -0.07 0.56 -0.17 -0.27 -0.29 -0.29 -0.34 -0.5 -0.48 0.4 0.41 0.37 0.82 0.76 0.65 0.39 0.4 0.49

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – 0
Bud Neck – – – – – – – – – – – – – – 0
Bud Site – – – – – – – – – – – – – – 0
Cell Periphery – – – – – – – – – – – – – – 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – 0
Endosome – – – – – – – – – – – – – – 0
Golgi – – – – – – – – – – – – – – 0
Mitochondria – – – – – – – – – – – – – – 0
Nuclear Periphery – – – – – – – – – – – – – – 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – 0
Peroxisomes – – – – – – – – – – – – – – 0
SpindlePole – – – – – – – – – – – – – – 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – 0
Cytoplasm – – – – – – – – – – – – – – 0
Nucleus – – – – – – – – – – – – – – 0
Vacuole – – – – – – – – – – – – – – 3.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.2907 0.1374 0.2149 -0.2441 -0.6304 0.2292 2.5921 0.1305 0.3917 0.0636 0.1137 0.2087 0.7889 -0.0841 -0.2992 -0.3308 -0.3614 -0.1532
Actin 0.0758 0.0002 0.0045 0.0002 0.0006 0.0143 0.1524 0.0021 0.0087 0.0005 0.0059 0.0084 0.0557 0.0011 0.0117 0.0072 0.0049 0.0158
Bud 0.002 0.0004 0.0011 0 0 0.0002 0.0022 0.0032 0.0014 0.0001 0.0004 0.0003 0.0013 0.0026 0.0044 0.0002 0.0002 0.0017
Bud Neck 0.005 0.0005 0.0004 0 0.0001 0.0269 0.0121 0.0005 0.0029 0.0027 0.0016 0.0141 0.0073 0.0005 0.0016 0.0014 0.0002 0.0227
Bud Periphery 0.0044 0.0005 0.0021 0.0001 0 0.0005 0.003 0.0045 0.0021 0.0002 0.0007 0.0007 0.0017 0.0022 0.0076 0.0002 0.0004 0.0021
Bud Site 0.009 0.0115 0.0069 0 0 0.0004 0.0278 0.0104 0.0373 0.0007 0.0015 0.0003 0.0086 0.0242 0.0225 0.0007 0.0003 0.0021
Cell Periphery 0.0014 0.0003 0.0005 0 0 0.0004 0.0016 0.0004 0.0005 0.0001 0.0001 0.0001 0.0005 0.0003 0.0004 0.0001 0.0001 0.0003
Cytoplasm 0.0339 0.0805 0.0951 0.0895 0.1378 0.1196 0.1115 0.1132 0.1222 0.1292 0.1021 0.1975 0.181 0.1966 0.1851 0.0832 0.218 0.187
Cytoplasmic Foci 0.0419 0.0062 0.0236 0.0037 0.0023 0.0174 0.0982 0.0111 0.0198 0.052 0.0291 0.0078 0.054 0.0208 0.0281 0.0187 0.0109 0.0127
Eisosomes 0.004 0.0002 0.0002 0.0002 0.0002 0.0001 0.0012 0.0001 0.0001 0 0.0001 0 0.0005 0.0001 0.0002 0.0001 0.0003 0.0002
Endoplasmic Reticulum 0.0107 0.0013 0.005 0.0004 0.0007 0.0022 0.0131 0.0015 0.0021 0.0007 0.0022 0.0007 0.005 0.0014 0.0023 0.0019 0.004 0.0023
Endosome 0.0619 0.0022 0.018 0.0006 0.003 0.0103 0.0825 0.0122 0.0071 0.0223 0.0468 0.0013 0.0553 0.0102 0.0222 0.0113 0.0162 0.0142
Golgi 0.0236 0.0001 0.0023 0.0001 0.0001 0.003 0.032 0.0016 0.0022 0.002 0.0089 0.0005 0.0166 0.0006 0.0028 0.0018 0.0022 0.003
Lipid Particles 0.0608 0.0004 0.0159 0.0007 0.0003 0.0041 0.0323 0.0009 0.0093 0.0074 0.0325 0.0006 0.0264 0.0002 0.007 0.0047 0.0032 0.0034
Mitochondria 0.0421 0.0002 0.0037 0.0004 0.0003 0.0018 0.0136 0.0023 0.0136 0.003 0.0134 0.0003 0.0057 0.0007 0.0034 0.0011 0.0035 0.0017
None 0.4982 0.8898 0.8043 0.9025 0.8122 0.7696 0.2786 0.8302 0.7445 0.7288 0.6507 0.7544 0.5191 0.7266 0.6796 0.8269 0.7013 0.7083
Nuclear Periphery 0.0232 0.0004 0.0011 0.0003 0.0075 0.013 0.0294 0.0005 0.0025 0.0005 0.0085 0.0009 0.0075 0.0005 0.0023 0.0066 0.0237 0.0108
Nucleolus 0.0307 0.0008 0.0024 0.0001 0.002 0.0004 0.006 0.0003 0.0018 0.0005 0.0023 0.0004 0.0013 0.0004 0.0004 0.0022 0.0007 0.0005
Nucleus 0.0089 0.0007 0.0017 0.0002 0.015 0.003 0.0119 0.0008 0.0037 0.0026 0.0027 0.0023 0.003 0.002 0.003 0.0111 0.0029 0.0019
Peroxisomes 0.0247 0.0002 0.0064 0.0003 0.0001 0.0081 0.0438 0.0008 0.0077 0.0414 0.0436 0.0018 0.0264 0.0005 0.0109 0.0048 0.0005 0.0012
Punctate Nuclear 0.0247 0.0028 0.0024 0.0003 0.0168 0.003 0.0371 0.0006 0.009 0.0008 0.0409 0.0063 0.016 0.0015 0.0013 0.0106 0.002 0.0058
Vacuole 0.0089 0.0006 0.002 0.0003 0.0007 0.0008 0.0065 0.0025 0.0013 0.004 0.0035 0.001 0.0053 0.0066 0.0029 0.0043 0.002 0.0017
Vacuole Periphery 0.0041 0.0001 0.0004 0.0001 0.0002 0.001 0.0032 0.0004 0.0003 0.0004 0.0024 0.0002 0.002 0.0004 0.0005 0.0009 0.0026 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 18.6701 15.021 8.6693 12.4543 12.7085 11.1959 16.4533 10.2507 13.0796 13.4001
Translational Efficiency 0.4022 0.4331 0.7305 0.4117 0.6232 0.7876 0.444 0.6641 0.4834 0.6186

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1028 171 1941 1901 740 264 205 1258 1768 435 2146 3159

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 620.91 734.56 876.41 793.95 677.88 721.83 927.59 824.81 644.75 726.83 881.30 806.24
Standard Deviation 71.57 73.98 106.07 109.40 83.52 713.96 110.25 118.97 81.78 558.17 107.54 114.31
Intensity Change Log 2 — 0.242496 0.497222 0.354664 — 0.090629 0.452457 0.283032 — 0.165229 0.474031 0.317721

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000818 0.000322 0.000620 0.002386 0.000480 0.000280 0.000358 0.002185 0.000676 0.000296 0.000595 0.002306
Bud Neck 0.025993 0.031320 0.016518 0.018565 0.030022 0.037415 0.019565 0.013315 0.027679 0.035019 0.016809 0.016474
Bud Site 0.013410 0.019771 0.028387 0.050138 0.019122 0.017840 0.011016 0.044701 0.015801 0.018599 0.026728 0.047973
Cell Periphery 0.000349 0.000171 0.000209 0.000389 0.000279 0.000357 0.000395 0.000387 0.000320 0.000284 0.000227 0.000388
Cytoplasm 0.387287 0.392311 0.502081 0.442736 0.508564 0.336306 0.325517 0.462146 0.438048 0.358322 0.485215 0.450465
Cytoplasmic Foci 0.315185 0.291144 0.071910 0.072919 0.240039 0.340273 0.109086 0.062305 0.283733 0.320961 0.075461 0.068692
Eisosomes 0.000721 0.000143 0.000081 0.000178 0.000397 0.000308 0.000225 0.000135 0.000585 0.000243 0.000095 0.000161
Endoplasmic Reticulum 0.001514 0.000906 0.005163 0.004674 0.001713 0.000503 0.003463 0.004363 0.001597 0.000662 0.005001 0.004550
Endosome 0.024039 0.023360 0.010525 0.009330 0.012936 0.041490 0.013392 0.006641 0.019392 0.034363 0.010799 0.008259
Golgi 0.011004 0.002921 0.000749 0.002167 0.005692 0.008431 0.000170 0.003813 0.008781 0.006265 0.000694 0.002823
Lipid Particles 0.024260 0.007561 0.004788 0.004251 0.010255 0.010294 0.010091 0.004060 0.018398 0.009220 0.005295 0.004175
Mitochondria 0.009746 0.009913 0.001003 0.003940 0.003429 0.010895 0.000289 0.000757 0.007102 0.010509 0.000935 0.002672
Mitotic Spindle 0.000564 0.003076 0.013580 0.016711 0.001759 0.005064 0.000260 0.011175 0.001064 0.004282 0.012308 0.014506
None 0.002159 0.001819 0.002010 0.001422 0.002844 0.001348 0.003613 0.003066 0.002446 0.001533 0.002163 0.002077
Nuclear Periphery 0.000460 0.000567 0.002371 0.001013 0.000326 0.000223 0.001382 0.000710 0.000404 0.000358 0.002276 0.000892
Nuclear Periphery Foci 0.000410 0.001286 0.003617 0.002091 0.000417 0.000228 0.004702 0.003674 0.000413 0.000644 0.003721 0.002721
Nucleolus 0.000996 0.001504 0.000602 0.000507 0.000409 0.001183 0.001012 0.000422 0.000750 0.001310 0.000641 0.000473
Nucleus 0.112496 0.119435 0.176038 0.162044 0.098935 0.091402 0.246238 0.171608 0.106820 0.102422 0.182744 0.165852
Peroxisomes 0.012450 0.021894 0.002103 0.003612 0.005661 0.015759 0.001262 0.003481 0.009608 0.018171 0.002022 0.003560
Vacuole 0.054101 0.069472 0.156945 0.196895 0.055915 0.077117 0.247637 0.199972 0.054860 0.074112 0.165608 0.198121
Vacuole Periphery 0.002037 0.001102 0.000699 0.004031 0.000806 0.003283 0.000326 0.001083 0.001522 0.002426 0.000664 0.002857

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.90 1.36 -3.63 -6.20 -5.18 2.18 -0.11 -3.16 -3.90 -3.04 3.58 0.89 -4.84 -7.34 -5.82
Bud Neck -0.66 4.53 4.51 2.51 -0.06 -1.23 2.43 5.59 5.99 0.95 -1.63 5.64 7.10 5.87 1.41
Bud Site -1.06 -3.57 -7.33 -3.23 -4.21 0.32 2.59 -2.29 -2.19 -4.86 -0.71 -2.58 -7.11 -4.29 -4.31
Cell Periphery 2.84 4.31 0.98 -2.28 -3.83 -1.23 -2.72 -0.06 1.16 2.44 0.70 4.40 0.79 -0.22 -3.74
Cytoplasm -0.14 -7.90 -1.94 -0.73 6.84 9.43 11.28 9.35 -3.12 -5.66 5.65 -1.46 4.68 -3.13 6.27
Cytoplasmic Foci 1.16 34.20 34.94 12.19 1.77 -6.06 12.68 23.48 20.17 5.51 -2.91 37.47 41.33 22.95 4.74
Eisosomes 8.89 10.08 8.88 -0.05 -4.83 1.81 4.17 7.43 5.59 6.50 7.52 12.17 10.99 4.80 -4.51
Endoplasmic Reticulum 1.71 -7.77 -6.44 -7.01 1.81 2.30 -4.28 -3.98 -11.34 1.27 3.39 -7.73 -7.31 -12.32 2.23
Endosome 0.17 8.25 9.64 3.20 3.01 -6.70 0.25 6.60 9.08 6.09 -4.40 7.86 11.48 8.83 5.81
Golgi 5.67 8.72 7.81 1.63 -1.79 -1.35 7.83 3.66 3.29 -2.31 1.93 10.64 8.60 3.81 -2.43
Lipid Particles 6.90 10.70 11.18 2.74 2.27 -0.01 0.63 4.63 5.47 4.57 5.77 10.56 11.87 5.91 4.34
Mitochondria 0.01 5.22 4.00 1.27 -3.47 -2.62 3.15 2.88 3.90 -2.78 -1.13 5.81 4.73 3.17 -3.06
Mitotic Spindle -1.11 -8.20 -6.96 -3.64 1.46 -0.92 1.54 -3.85 -1.36 -4.93 -1.37 -7.76 -7.78 -3.01 1.51
None 0.38 0.25 2.65 0.82 3.40 1.78 -0.08 0.39 -2.20 0.32 1.84 0.66 1.56 -0.70 1.29
Nuclear Periphery -0.50 -8.15 -7.51 -3.48 4.60 0.76 -4.89 -6.40 -16.47 1.91 0.40 -8.75 -9.78 -8.87 5.14
Nuclear Periphery Foci -1.08 -10.24 -5.58 -0.77 4.72 2.30 -5.18 -6.33 -6.89 2.37 -0.71 -11.32 -8.42 -4.46 4.42
Nucleolus -0.95 2.06 3.16 2.36 1.92 -4.27 -1.69 0.99 4.40 1.88 -2.37 0.50 3.27 4.32 3.20
Nucleus -0.62 -11.22 -10.03 -4.59 1.84 0.65 -7.83 -12.58 -8.86 2.61 0.44 -14.87 -15.66 -9.70 1.95
Peroxisomes -1.81 10.14 8.93 3.82 -2.87 -3.76 5.97 4.34 5.29 -2.34 -3.24 11.26 9.84 6.23 -2.78
Vacuole -2.02 -23.43 -32.36 -18.19 -9.95 -2.91 -12.85 -28.21 -19.73 0.95 -3.63 -26.96 -42.85 -26.72 -11.41
Vacuole Periphery 2.12 4.02 -0.68 -2.04 -2.96 -3.50 5.93 0.88 3.62 -1.11 -1.81 4.36 -0.52 1.07 -2.91
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Potential noncatalytic subunit for phospholipid translocase Dnf3p; YNR048W has a paralog, CDC50, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (44%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-10

YNR048W

YNR048W


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ynr048w-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available