Standard name
Human Ortholog
Description Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.07 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.09 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.08 0 0.1 0.08 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.85 0.91 0.92 0.97 0.88 0.81 0.85 0.92 0.96 0.94 0.94 0.91 0.96 0.97 0.99 0.87 0.85 0.86 0.23 0.34 0.3 0.39 0.4 0.56
Endoplasmic Reticulum 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.05 0.05 0.2 0.15 0.09 0.06 0.1 0.12 0.17 0 0 0 0 0 0 0.06 0 0.17 0.06 0.06 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.05 0 0 0.05 0.06 0 0 0 0 0 0 0 0 0 0.13 0.17 0.14 0.41 0.37 0.28 0.23 0.22 0.21
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 4 2 0 1 2 0 2 1 0 1 0 0 7 2 0 1 0 0 2 13 4 8 20 11
Bud 1 4 3 0 5 3 4 6 5 3 4 4 3 1 0 0 1 0 3 15 1 11 10 7
Bud Neck 0 4 4 1 0 0 1 6 1 1 1 2 3 1 0 3 3 0 9 28 5 14 22 12
Bud Site 1 1 1 0 1 0 0 1 0 1 0 0 2 0 0 0 0 0 – – – – – –
Cell Periphery 2 4 1 3 1 0 0 2 0 0 1 0 1 1 2 3 1 4 0 3 5 2 5 6
Cytoplasm 62 272 141 118 143 113 155 195 137 182 147 163 325 222 240 413 321 272 21 112 41 54 110 164
Endoplasmic Reticulum 7 6 4 0 4 2 3 0 1 0 0 0 2 0 1 33 14 20 2 3 1 1 10 5
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 6 2 5 5 8 4 1 5 3
Golgi 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 2 1 0 2 1 1 0 2 1
Mitochondria 1 6 6 6 8 28 28 20 8 20 18 30 1 0 1 10 1 7 5 12 24 8 18 13
Nucleus 0 0 0 1 3 2 5 3 0 1 1 0 0 1 0 11 4 5 0 0 0 0 0 0
Nuclear Periphery 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 1 0 0 1 1 0 0 1 0 0 0 0 0 0 0
SpindlePole 0 2 2 0 0 1 0 0 0 0 1 0 3 0 0 3 5 6 0 2 2 0 3 1
Vac/Vac Membrane 0 14 0 1 8 8 8 5 2 3 2 5 1 0 0 64 63 44 39 122 39 31 61 61
Unique Cell Count 73 299 153 122 162 140 182 211 142 193 156 179 338 228 242 475 377 317 95 333 140 138 278 294
Labelled Cell Count 78 316 163 131 175 157 206 240 154 213 175 204 350 232 244 550 419 364 95 333 140 138 278 294


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 4.1 3.1 3.1 3.5 3.3 3.2 3.4 3.3 2.8 3.0 2.6 4.3 4.2 3.8 6.3 6.7 6.6 4.4 4.4 5.0
Std Deviation (1e-4) 1.1 0.8 0.6 0.9 1.2 0.8 1.0 1.1 1.8 1.3 1.2 0.8 0.9 0.9 0.9 1.7 2.2 2.5 1.0 1.3 1.4
Intensity Change (Log2) – – – -0.02 0.19 0.1 0.04 0.11 0.07 -0.12 -0.06 -0.23 0.46 0.44 0.28 1.01 1.11 1.09 0.49 0.51 0.68

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 4.8 5.4 4.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.2178 0.1035 -0.2639 -0.3198 -0.4812 0.3327 1.9714 1.9879 1.3652 1.8043 2.6201 1.7737 2.8496 2.704 2.6431 2.8858 2.5133 2.913
Actin 0.0724 0.0015 0.0001 0.0198 0.0163 0.0189 0.0281 0.0003 0.0037 0.0003 0.0305 0.0023 0 0.001 0 0.0014 0.0003 0.0001
Bud 0.0037 0.001 0.0015 0.0062 0.0004 0.0005 0.0007 0.0029 0.0025 0.0003 0.0011 0.001 0.0001 0.0075 0.0001 0.0002 0.0012 0.0002
Bud Neck 0.0186 0.0004 0.0003 0.0024 0.0007 0.0014 0.0022 0.0001 0.0069 0.0001 0.0039 0.0009 0.0004 0.0003 0 0.0001 0.0001 0.0117
Bud Periphery 0.0074 0.0017 0.0017 0.0228 0.0007 0.0012 0.0014 0.0032 0.0029 0.0006 0.0013 0.0013 0.0002 0.0089 0.0001 0.0003 0.001 0.0002
Bud Site 0.0148 0.0054 0.0003 0.0024 0.0009 0.0006 0.0062 0.0019 0.0045 0.0002 0.0054 0.0005 0.0007 0.0079 0.0001 0.0002 0.0001 0.0001
Cell Periphery 0.0034 0.001 0.0003 0.001 0.0002 0.0002 0.0006 0.0004 0.0005 0.0003 0.0003 0.0002 0.001 0.0008 0.0001 0.0001 0.0001 0.0002
Cytoplasm 0.155 0.2425 0.2534 0.153 0.3082 0.3337 0.1117 0.1169 0.1234 0.1554 0.1294 0.2315 0.0865 0.0813 0.0646 0.1452 0.0774 0.184
Cytoplasmic Foci 0.0628 0.0208 0.0382 0.0678 0.0177 0.0666 0.0311 0.0235 0.0214 0.0241 0.0181 0.0354 0.0241 0.0226 0.0081 0.0296 0.0052 0.0755
Eisosomes 0.0013 0.0002 0.0001 0.0004 0.0001 0.0003 0.0006 0.0001 0.0002 0 0.0004 0.0001 0.0001 0.0002 0.0001 0.0006 0.0003 0.0001
Endoplasmic Reticulum 0.0061 0.0045 0.0047 0.0064 0.0016 0.0045 0.0049 0.0019 0.0024 0.0013 0.0168 0.0018 0.0017 0.0017 0.0009 0.0016 0.0004 0.0022
Endosome 0.0541 0.0138 0.038 0.0483 0.0189 0.0571 0.0365 0.0166 0.0241 0.028 0.0803 0.0112 0.0289 0.0078 0.008 0.0252 0.0002 0.0571
Golgi 0.0169 0.0009 0.0007 0.006 0.0098 0.0089 0.0033 0.0004 0.0016 0.0019 0.0155 0.0014 0.0005 0.0006 0.0002 0.0006 0.0001 0.0014
Lipid Particles 0.036 0.006 0.0088 0.0096 0.0112 0.0129 0.0076 0.0021 0.0053 0.0337 0.015 0.0017 0.0026 0.0027 0.0004 0.0012 0.0003 0.0027
Mitochondria 0.0377 0.0009 0.0009 0.0202 0.0081 0.0157 0.0029 0.0007 0.0014 0.0014 0.0058 0.0013 0.001 0.0017 0.0003 0.0016 0.0003 0.0017
None 0.4133 0.6767 0.6351 0.5465 0.5663 0.4309 0.6823 0.8197 0.7818 0.6913 0.5691 0.6931 0.8077 0.8232 0.9065 0.772 0.9019 0.6441
Nuclear Periphery 0.0168 0.0011 0.0012 0.0084 0.0015 0.0126 0.0182 0.0006 0.001 0.003 0.0516 0.0019 0.0004 0.0006 0.0004 0.0009 0.0008 0.0006
Nucleolus 0.004 0.0005 0.0004 0.0006 0.0003 0.0009 0.0021 0.0003 0.0005 0.0016 0.0016 0.0007 0.0006 0.0017 0.0001 0.0003 0.0006 0.0003
Nucleus 0.0053 0.0016 0.0015 0.0026 0.001 0.0047 0.0148 0.0008 0.0012 0.0349 0.0209 0.002 0.0009 0.0023 0.0006 0.0009 0.0022 0.001
Peroxisomes 0.0261 0.0059 0.0006 0.0056 0.0031 0.0034 0.0077 0.0003 0.0016 0.0036 0.0045 0.0041 0.0002 0.0013 0.0001 0.001 0.0001 0.0015
Punctate Nuclear 0.0057 0.0009 0.0016 0.0044 0.0012 0.01 0.0222 0.0005 0.0019 0.0079 0.0134 0.0026 0.0003 0.0014 0.0002 0.0006 0.0069 0.0007
Vacuole 0.0347 0.0122 0.0093 0.0404 0.0294 0.0124 0.0128 0.0062 0.0103 0.0091 0.0104 0.0043 0.0412 0.0218 0.0081 0.0141 0.0005 0.0129
Vacuole Periphery 0.0039 0.0007 0.0013 0.0254 0.0024 0.0024 0.002 0.0005 0.001 0.0011 0.0048 0.0007 0.001 0.0026 0.0009 0.0021 0.0001 0.0016

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.7572 5.8818 42.9907 191.9225 81.8955 2.6304 6.9135 10.3357 93.8654 161.3306
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1572 1179 784 1041 1599 1628 156 236 3171 2807 940 1277

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 597.27 699.76 889.44 826.73 642.76 702.46 887.39 835.94 620.21 701.33 889.10 828.43
Standard Deviation 77.99 95.93 109.69 117.04 75.22 92.41 106.95 123.83 79.91 93.92 109.24 118.38
Intensity Change Log 2 — 0.228477 0.574514 0.469033 — 0.128136 0.465288 0.379119 — 0.177338 0.518931 0.423127

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000626 0.000638 0.000668 0.007433 0.001288 0.001289 0.000419 0.007182 0.000960 0.001015 0.000627 0.007387
Bud Neck 0.185823 0.046144 0.012984 0.018786 0.109935 0.066158 0.001925 0.014459 0.147556 0.057752 0.011148 0.017987
Bud Site 0.090134 0.027642 0.033041 0.077329 0.072606 0.041375 0.002818 0.056720 0.081296 0.035607 0.028026 0.073520
Cell Periphery 0.001253 0.000131 0.000351 0.001385 0.000410 0.000236 0.000287 0.002253 0.000828 0.000192 0.000341 0.001545
Cytoplasm 0.358092 0.435599 0.489208 0.413276 0.455364 0.336555 0.303809 0.341055 0.407142 0.378156 0.458440 0.399929
Cytoplasmic Foci 0.136076 0.194555 0.022016 0.028622 0.150927 0.233812 0.022573 0.047331 0.143564 0.217323 0.022108 0.032080
Eisosomes 0.000615 0.000137 0.000061 0.000448 0.000362 0.000379 0.000094 0.000846 0.000487 0.000277 0.000067 0.000522
Endoplasmic Reticulum 0.001131 0.000552 0.007083 0.005697 0.000579 0.000706 0.007142 0.004681 0.000853 0.000641 0.007092 0.005510
Endosome 0.022134 0.036878 0.004547 0.005552 0.013173 0.053019 0.004109 0.017526 0.017616 0.046239 0.004475 0.007765
Golgi 0.002111 0.004269 0.000119 0.007673 0.002428 0.008757 0.000088 0.010378 0.002271 0.006872 0.000114 0.008173
Lipid Particles 0.008833 0.004760 0.002281 0.002376 0.004843 0.006583 0.002948 0.002765 0.006821 0.005818 0.002392 0.002448
Mitochondria 0.005701 0.006442 0.000376 0.007098 0.002450 0.012448 0.000288 0.001454 0.004062 0.009926 0.000361 0.006055
Mitotic Spindle 0.000677 0.004214 0.000694 0.032674 0.000952 0.009250 0.000402 0.075852 0.000816 0.007135 0.000646 0.040654
None 0.002765 0.002628 0.003645 0.005015 0.002857 0.000636 0.006572 0.001334 0.002811 0.001473 0.004131 0.004335
Nuclear Periphery 0.000214 0.000266 0.001133 0.000957 0.000130 0.000211 0.001662 0.000880 0.000172 0.000234 0.001221 0.000943
Nuclear Periphery Foci 0.000412 0.000426 0.004130 0.001821 0.000374 0.000219 0.003688 0.001987 0.000393 0.000306 0.004057 0.001852
Nucleolus 0.001049 0.001684 0.000340 0.000352 0.000865 0.000790 0.000545 0.000672 0.000956 0.001165 0.000374 0.000411
Nucleus 0.067342 0.065731 0.300130 0.178566 0.085502 0.041623 0.516723 0.119032 0.076499 0.051749 0.336075 0.167563
Peroxisomes 0.006925 0.021508 0.000573 0.001532 0.007847 0.032030 0.000313 0.005194 0.007390 0.027611 0.000530 0.002209
Vacuole 0.106859 0.144066 0.116357 0.200604 0.086474 0.150881 0.123449 0.273055 0.096580 0.148018 0.117534 0.213993
Vacuole Periphery 0.001228 0.001730 0.000264 0.002803 0.000635 0.003042 0.000144 0.015342 0.000929 0.002491 0.000244 0.005120

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.12 -1.13 -2.89 -2.87 -2.74 0.01 3.08 -1.08 -1.09 -1.69 -0.34 1.71 -2.79 -2.72 -3.11
Bud Neck 18.43 23.85 24.04 9.67 -0.54 7.43 20.72 17.51 14.96 -3.60 18.55 29.43 29.59 18.65 -1.26
Bud Site 12.66 10.62 8.61 -2.96 -2.17 6.76 17.15 7.08 2.70 -3.88 13.41 13.29 10.09 -0.46 -2.86
Cell Periphery 4.72 3.81 2.28 -4.02 -2.31 5.23 2.91 -0.81 -1.18 -1.05 5.34 4.09 0.87 -3.50 -2.43
Cytoplasm -6.81 -5.87 2.12 8.18 7.23 12.26 10.02 9.73 3.24 -0.94 4.05 0.58 9.09 5.64 6.40
Cytoplasmic Foci -7.78 25.96 26.01 29.47 -0.38 -11.96 25.36 21.82 32.77 -2.25 -14.55 37.08 36.48 47.53 -1.32
Eisosomes 9.08 10.32 5.14 -1.73 -2.88 -0.32 10.53 0.19 0.29 -1.94 5.99 14.35 4.23 0.46 -3.46
Endoplasmic Reticulum 3.82 -10.01 -7.00 -8.21 3.40 -1.10 -5.93 -7.66 -7.45 2.56 2.22 -11.94 -9.09 -9.61 4.08
Endosome -4.83 13.99 15.03 13.61 1.78 -15.39 8.36 2.80 15.02 -1.69 -14.76 15.87 15.46 23.48 0.30
Golgi -3.30 11.50 -0.39 1.06 -2.08 -7.97 6.51 -0.38 2.52 -1.54 -8.75 10.77 -0.40 3.48 -2.50
Lipid Particles 4.48 7.38 7.66 4.39 0.26 -2.49 2.69 4.43 6.31 1.36 1.99 8.44 9.33 8.54 0.70
Mitochondria -0.22 4.87 1.74 2.18 -2.47 -8.13 6.56 4.68 9.78 -2.86 -5.88 6.51 1.38 6.05 -2.56
Mitotic Spindle -3.61 -1.41 -7.18 -5.96 -6.95 -5.30 0.03 -3.48 -2.62 -3.49 -6.36 -1.22 -7.90 -5.80 -7.73
None 0.33 -1.11 -2.20 -2.39 -1.41 4.38 -1.03 1.69 -3.85 1.83 3.74 -1.37 -1.77 -4.57 -0.61
Nuclear Periphery -1.10 -12.92 -16.01 -17.58 -5.07 -3.10 -12.47 -10.58 -10.02 0.96 -2.03 -18.75 -20.40 -20.37 -4.38
Nuclear Periphery Foci -0.17 -4.59 -9.39 -8.38 2.71 2.75 -4.42 -3.97 -4.32 1.20 1.48 -5.17 -10.19 -10.58 2.87
Nucleolus -1.39 5.82 5.64 2.37 -0.66 0.92 2.09 2.06 1.86 0.16 -0.68 4.27 4.08 3.00 -0.56
Nucleus -0.55 -27.56 -21.36 -20.44 7.35 12.00 -16.51 -7.51 -10.64 10.55 8.52 -30.87 -21.94 -25.17 11.03
Peroxisomes -7.22 9.71 9.26 11.11 -2.03 -12.46 12.22 7.11 15.66 -2.79 -14.35 15.19 13.65 19.99 -3.33
Vacuole -7.01 -5.08 -18.95 -13.75 -13.01 -12.52 -6.00 -15.36 -11.86 -7.11 -13.52 -8.53 -24.97 -17.81 -14.87
Vacuole Periphery -2.18 9.75 0.54 1.45 -2.03 -8.02 10.06 -1.24 -0.53 -1.39 -7.91 12.16 -1.13 0.99 -2.15
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother
Localization
Cell Percentages cytoplasm (26%), vacuole (3%), mixed (37%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Dse4

Dse4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dse4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available