Standard name
Human Ortholog
Description Protein with a possible role in phospholipid biosynthesis; null mutant displays an inositol-excreting phenotype that is suppressed by exogenous choline; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.6 0.68 0.52 0.42 0.42 0.44 0.33 0.32 0.28 0.3 0.28 0.27 0.76 0.62 0.61 0.46 0.47 0.47 0.62 0.62 0.57 0.64 0.55 0.54
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.07 0.05 0.18 0.25 0.25 0.23 0.23 0.3 0.21 0 0 0 0 0 0 0 0 0 0.05 0.06 0
Nucleus 0 0 0 0 0.08 0.06 0.08 0.09 0.12 0.14 0.14 0.12 0.05 0 0 0 0 0 0.18 0.19 0.11 0.05 0.06 0.05
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.45 0.38 0.58 0.61 0.57 0.45 0.51 0.46 0.51 0.5 0.44 0.54 0.25 0.49 0.48 0.61 0.62 0.6 0.12 0.09 0.08 0.12 0.16 0.18
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 2 0 2 3
Bud 0 0 1 0 1 4 5 8 8 4 4 6 0 0 0 0 0 1 0 5 9 1 5 15
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 3 2 1 1 4
Bud Site 0 0 0 0 1 1 0 0 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 0 0 0 1 4 2 2 0 1 0 0 0 1 2 0 0 0 0 0 0 0
Cytoplasm 67 165 232 138 210 258 261 220 215 236 167 186 81 112 138 77 87 85 85 157 270 57 179 192
Endoplasmic Reticulum 1 2 2 0 3 2 2 2 3 4 2 2 4 0 3 2 2 4 0 0 26 1 11 10
Endosome 0 1 6 8 7 5 9 2 7 2 3 11 0 1 3 0 2 1 1 1 16 0 10 16
Golgi 1 0 1 0 0 0 0 0 0 0 0 1 0 0 0 1 0 3 1 0 1 0 1 0
Mitochondria 3 5 12 22 23 106 199 171 174 178 181 142 0 0 0 3 3 1 1 3 4 4 20 11
Nucleus 4 6 8 13 42 36 67 65 89 107 81 85 5 5 0 2 5 6 25 49 53 4 19 16
Nuclear Periphery 0 0 0 0 3 3 5 8 4 2 2 10 0 0 0 1 0 0 2 1 31 1 6 6
Nucleolus 1 0 0 0 0 2 7 6 2 3 3 4 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0
SpindlePole 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 2 2 8 1 6 9
Vac/Vac Membrane 50 93 258 198 288 263 406 322 387 390 263 371 26 89 108 103 114 109 16 23 37 10 52 63
Unique Cell Count 111 243 444 326 503 583 791 694 755 785 596 687 106 182 227 169 184 181 139 256 478 89 327 359
Labelled Cell Count 127 272 522 379 578 680 962 808 893 929 706 820 116 207 252 191 215 210 139 256 478 89 327 359


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 5.9 6.6 6.1 6.6 6.2 6.7 6.7 7.6 7.5 7.9 8.2 6.1 7.0 7.6 8.8 8.8 8.6 – 6.4 7.1
Std Deviation (1e-4) 1.6 1.1 1.7 1.4 1.5 1.8 2.0 1.8 2.2 2.3 2.7 2.8 1.2 1.5 1.1 3.0 2.0 3.0 – 1.2 1.4
Intensity Change (Log2) – – – -0.11 -0.02 -0.09 0.01 0.02 0.2 0.18 0.25 0.3 -0.11 0.08 0.2 0.41 0.41 0.38 – -0.04 0.1

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -2.7 -3.2 -2.5 -6.6 -6.9 -8.2 -7.7 -7.9 -8.6 4.5 2.1 2.1 -1.5 -1.1 -1.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 1.1 0.1 0 -0.3 0 0 0 0 0.3 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.7 1.5 7.7 10.1 9.8 9.4 9.3 11.4 8.6 0 0 0 0 0 0
Nucleus 1.8 4.5 3.4 4.7 5.1 6.1 6.8 6.7 6.3 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0.7 -0.3 -4.1 -2.3 -3.9 -2.3 -2.8 -4.5 -1.4 -6.2 -2.1 -2.6 0.6 0.9 0.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.2989 0.1636 0.0824 -0.2531 -0.2533 0.1898 1.4756 1.8449 1.6052 1.0876 1.4688 1.7665 0.2016 0.683 0.4367 0.2948 0.549 0.314
Actin 0.0063 0.0009 0.0006 0.0005 0.0146 0.0017 0.0067 0.0015 0.008 0.0332 0.0288 0.0014 0.017 0.0001 0.0029 0.0009 0.0085 0.0049
Bud 0.0001 0.0005 0.0002 0.0001 0.0015 0.0001 0.0004 0.0017 0.0011 0.0003 0.0003 0.0008 0.0002 0 0.0003 0.0001 0.0009 0.0006
Bud Neck 0.0007 0.0005 0.0003 0.0007 0.0009 0.001 0.005 0.0003 0.0007 0.0021 0.0008 0.0017 0.0009 0.0001 0.0003 0.0002 0.0004 0.0004
Bud Periphery 0.0001 0.0003 0.0001 0.0001 0.0038 0 0.0004 0.0013 0.0008 0.0004 0.0002 0.0016 0.0002 0 0.0006 0.0001 0.0006 0.005
Bud Site 0.0002 0.0112 0.0005 0.0002 0.0088 0.0001 0.0073 0.0047 0.0069 0.0013 0.0006 0.0002 0.0016 0.0004 0.0006 0.0002 0.0018 0.0001
Cell Periphery 0.0001 0.0001 0.0001 0 0.0002 0 0.0002 0.0001 0.0001 0.0001 0 0 0.0002 0.0001 0.0001 0.0001 0 0.0001
Cytoplasm 0.5047 0.5257 0.5228 0.5088 0.4573 0.5247 0.4534 0.539 0.547 0.3922 0.3769 0.5858 0.4723 0.6368 0.5444 0.5598 0.3479 0.4993
Cytoplasmic Foci 0.01 0.0126 0.0079 0.0124 0.0075 0.0112 0.0162 0.0084 0.0093 0.0099 0.0275 0.0107 0.0145 0.0079 0.0204 0.0066 0.0616 0.0083
Eisosomes 0.0001 0.0001 0.0001 0 0.0004 0 0.0002 0.0001 0.0001 0.0004 0.0001 0 0.0002 0 0.0001 0 0 0.0001
Endoplasmic Reticulum 0.0166 0.0088 0.0106 0.012 0.007 0.0079 0.0095 0.0079 0.0136 0.0078 0.0027 0.006 0.0272 0.0084 0.0083 0.0162 0.003 0.0063
Endosome 0.0097 0.0112 0.0071 0.0152 0.0123 0.0134 0.0125 0.006 0.0088 0.0073 0.0087 0.0057 0.0161 0.0037 0.0119 0.0174 0.0734 0.0083
Golgi 0.0003 0.0006 0.0002 0.0002 0.0015 0.0003 0.0015 0.0002 0.001 0.0016 0.0019 0.0001 0.0043 0.0001 0.0021 0.0004 0.0407 0.0069
Lipid Particles 0.0007 0.0008 0.0003 0.0006 0.0018 0.0006 0.002 0.0005 0.001 0.0012 0.0057 0.0001 0.0158 0.0004 0.002 0.0001 0.0041 0.01
Mitochondria 0.0004 0.0008 0.0007 0.0008 0.0046 0.0005 0.0011 0.0009 0.0018 0.0017 0.0009 0.0008 0.0043 0.0001 0.0019 0.001 0.0154 0.0149
None 0.3481 0.3451 0.3526 0.2713 0.3488 0.3167 0.3523 0.3466 0.3122 0.437 0.4086 0.2639 0.327 0.2974 0.3491 0.378 0.3608 0.4093
Nuclear Periphery 0.0193 0.0145 0.0145 0.0286 0.0121 0.0123 0.0216 0.0104 0.0154 0.0159 0.0031 0.011 0.0216 0.0111 0.0146 0.0079 0.0052 0.0055
Nucleolus 0.0003 0.0005 0.0003 0.0007 0.0035 0.0004 0.0013 0.0004 0.0009 0.0005 0.0003 0.0004 0.0008 0.0001 0.0002 0.0001 0.0002 0.0001
Nucleus 0.0731 0.0525 0.0708 0.1292 0.1 0.0964 0.0884 0.0623 0.0545 0.076 0.0705 0.0967 0.0585 0.0291 0.0265 0.0075 0.0364 0.0147
Peroxisomes 0.0001 0.0005 0.0002 0.0003 0.0026 0.0002 0.0022 0.0003 0.0005 0.002 0.0319 0.0002 0.0069 0 0.0021 0.0001 0.0341 0.0018
Punctate Nuclear 0.0055 0.0088 0.0059 0.0133 0.0066 0.0098 0.014 0.0051 0.0139 0.0071 0.0295 0.0107 0.0075 0.0024 0.0086 0.0009 0.0018 0.0009
Vacuole 0.003 0.0033 0.0037 0.0042 0.0034 0.0021 0.0032 0.0017 0.0019 0.0014 0.0008 0.0015 0.0025 0.0016 0.002 0.0016 0.0021 0.0011
Vacuole Periphery 0.0007 0.0006 0.0006 0.001 0.0008 0.0005 0.0006 0.0003 0.0006 0.0005 0.0002 0.0004 0.0007 0.0002 0.0013 0.0008 0.001 0.0013

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.2118 2.6623 4.9388 10.97 9.6533 10.4178 10.4309 15.897 13.9883 10.7667
Translational Efficiency 2.3041 5.7792 2.3862 1.324 1.4096 1.9682 1.9655 1.2935 2.1908 1.9689

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1635 1571 2171 1346 2128 1515 192 1987 3763 3086 2363 3333

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 776.69 778.67 900.54 1205.31 774.43 788.12 1089.87 1094.48 775.41 783.31 915.92 1139.24
Standard Deviation 102.86 128.05 124.95 403.84 98.97 126.19 218.04 222.84 100.69 127.23 144.51 313.72
Intensity Change Log 2 — 0.003673 0.213451 0.633993 — 0.025280 0.492949 0.499039 — 0.014502 0.359755 0.568192

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000178 0.000151 0.000246 0.003995 0.000083 0.000477 0.001401 0.000450 0.000124 0.000311 0.000340 0.001882
Bud Neck 0.002621 0.004780 0.006190 0.012685 0.002444 0.013958 0.007480 0.008588 0.002521 0.009286 0.006295 0.010242
Bud Site 0.002570 0.004373 0.004820 0.030638 0.001120 0.010712 0.003598 0.014000 0.001750 0.007485 0.004721 0.020719
Cell Periphery 0.000103 0.000099 0.000090 0.000675 0.000056 0.000156 0.000201 0.000189 0.000077 0.000127 0.000099 0.000385
Cytoplasm 0.465667 0.458170 0.231411 0.312966 0.507607 0.430331 0.064079 0.404821 0.489384 0.444503 0.217815 0.367726
Cytoplasmic Foci 0.055378 0.029455 0.001666 0.007248 0.060484 0.092381 0.001157 0.005240 0.058265 0.060347 0.001625 0.006051
Eisosomes 0.000036 0.000024 0.000016 0.003895 0.000025 0.000059 0.000042 0.000017 0.000030 0.000041 0.000018 0.001583
Endoplasmic Reticulum 0.004116 0.002896 0.003994 0.004273 0.002746 0.002749 0.013937 0.003546 0.003341 0.002824 0.004802 0.003840
Endosome 0.003960 0.002535 0.001115 0.002103 0.002456 0.008051 0.001690 0.003117 0.003110 0.005243 0.001162 0.002708
Golgi 0.001162 0.000654 0.000059 0.002680 0.000660 0.004162 0.000473 0.001128 0.000878 0.002376 0.000093 0.001755
Lipid Particles 0.005457 0.002290 0.000516 0.001371 0.003121 0.005908 0.001347 0.000771 0.004136 0.004066 0.000583 0.001014
Mitochondria 0.002333 0.002458 0.001124 0.003089 0.001656 0.005222 0.001236 0.002417 0.001950 0.003815 0.001133 0.002688
Mitotic Spindle 0.003430 0.004473 0.007510 0.057973 0.003213 0.015855 0.006345 0.035305 0.003307 0.010061 0.007415 0.044459
None 0.007203 0.010836 0.007474 0.013212 0.004381 0.006026 0.004702 0.013442 0.005607 0.008475 0.007249 0.013349
Nuclear Periphery 0.003826 0.002156 0.003358 0.002825 0.002890 0.001964 0.003135 0.003105 0.003297 0.002062 0.003340 0.002992
Nuclear Periphery Foci 0.005258 0.001901 0.000727 0.002422 0.001637 0.002840 0.005780 0.001641 0.003210 0.002362 0.001137 0.001957
Nucleolus 0.002417 0.001788 0.000630 0.000767 0.001051 0.002547 0.001134 0.000915 0.001644 0.002161 0.000671 0.000855
Nucleus 0.409924 0.444861 0.708175 0.495445 0.382980 0.356413 0.845389 0.463674 0.394687 0.401440 0.719324 0.476504
Peroxisomes 0.001287 0.001077 0.000292 0.000285 0.000638 0.005264 0.000306 0.000255 0.000920 0.003132 0.000293 0.000267
Vacuole 0.022437 0.024160 0.020402 0.039486 0.020493 0.033649 0.035713 0.035945 0.021338 0.028819 0.021646 0.037375
Vacuole Periphery 0.000639 0.000864 0.000185 0.001966 0.000260 0.001277 0.000854 0.001432 0.000425 0.001067 0.000240 0.001648

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.28 -2.33 -3.01 -3.06 -2.67 -4.14 -9.93 -9.74 -0.12 7.18 -3.59 -6.04 -4.14 -3.16 -2.49
Bud Neck -3.00 -6.48 -12.79 -10.40 -7.38 -7.61 -7.41 -11.82 1.83 -1.02 -8.18 -8.34 -17.28 -4.01 -6.35
Bud Site -1.44 -1.72 -7.08 -6.10 -6.28 -7.05 -5.65 -7.80 0.78 -3.95 -6.45 -3.57 -10.22 -4.01 -6.84
Cell Periphery 0.38 1.49 -8.20 -8.20 -8.54 -6.83 -8.79 -7.90 0.29 3.33 -5.39 -5.31 -10.37 -7.19 -8.99
Cytoplasm 1.59 33.89 28.10 25.38 -2.78 8.84 54.02 27.47 14.66 -28.86 7.67 50.81 38.40 27.10 -13.16
Cytoplasmic Foci 9.00 23.17 21.14 14.00 -6.87 -7.26 26.05 24.69 24.10 -7.14 -0.68 34.65 32.52 26.90 -9.19
Eisosomes 4.97 7.16 -1.29 -1.31 -1.31 -11.19 -5.46 0.36 11.74 5.59 -6.48 3.53 -1.29 -1.25 -1.31
Endoplasmic Reticulum 2.81 -3.97 -2.69 -5.78 0.87 -0.26 -9.63 -5.55 -5.75 8.46 1.53 -10.15 -5.75 -8.06 5.60
Endosome 3.90 9.28 7.32 3.19 -1.51 -8.68 0.71 1.98 9.42 0.96 -5.38 9.89 6.24 9.50 -2.55
Golgi 1.05 2.36 0.48 -0.50 -1.92 -3.71 1.19 0.66 3.99 -0.45 -2.83 3.22 0.83 3.47 -2.41
Lipid Particles 5.65 10.64 7.67 1.36 -6.50 -5.40 4.06 10.14 10.17 2.32 0.18 14.67 11.76 9.09 -6.80
Mitochondria 0.02 1.93 -0.54 -0.52 -6.07 -4.14 0.26 -1.38 3.80 -3.46 -3.11 1.78 -1.34 2.68 -6.90
Mitotic Spindle -0.41 -3.87 -10.17 -9.96 -8.41 -4.97 -1.94 -10.74 -5.50 -3.49 -4.42 -4.69 -14.78 -11.29 -10.80
None -2.85 0.42 -5.71 -0.80 -6.64 -3.22 0.62 -13.64 -10.17 -10.52 -4.27 -2.05 -13.92 -5.87 -10.15
Nuclear Periphery 4.24 -1.52 -3.58 -9.18 -3.36 2.75 -2.21 -6.88 -9.62 -0.30 4.81 -4.63 -7.58 -12.90 -3.94
Nuclear Periphery Foci 4.38 6.70 3.60 -0.89 -4.23 -1.82 -1.99 -1.80 0.93 1.75 1.71 5.08 2.39 0.28 -3.33
Nucleolus 1.27 3.37 2.24 1.82 -1.93 -5.27 -0.71 -1.76 3.84 -0.77 -1.67 3.75 1.33 3.96 -3.72
Nucleus -4.12 -36.26 -15.07 -10.95 16.27 2.76 -26.21 -18.56 -18.66 16.23 -1.50 -50.51 -23.73 -20.29 25.28
Peroxisomes 0.42 2.92 3.14 2.75 0.22 -7.27 2.98 4.57 8.10 1.61 -5.69 3.64 4.54 8.38 0.35
Vacuole -2.51 -5.16 -15.03 -13.43 -11.85 -6.52 -5.29 -15.70 -9.51 -1.21 -6.62 -7.25 -21.70 -16.46 -13.85
Vacuole Periphery -0.57 2.12 -0.03 0.47 -1.75 -5.16 -0.92 -1.29 2.28 -0.17 -3.47 2.30 -0.84 1.88 -2.26
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein with a possible role in phospholipid biosynthesis; null mutant displays an inositol-excreting phenotype that is suppressed by exogenous choline; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cytoplasm (43%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Opi10

Opi10


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Opi10-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available