Standard name
Human Ortholog
Description Myo-inositol transporter; member of the sugar transporter superfamily; expressed constitutively; ITR2 has a paralog, ITR1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.11 0.17 0.21 0.12 0.15 0.14 0.1 0.13 0.11 0.13 0.16 0.08 0.05 0.05 0.05 – 0.08 0.05 0.11 0.08 0.1 0.09 0.07 0.06
Bud 0 0.06 0.05 0.07 0 0 0 0.1 0.06 0.06 0.06 0.05 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0.06 0.07 0 0.05 0.05 0.05
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0.36 0.54 0.49 0.43 0.42 0.35 0.33 0.3 0.34 0.37 0.32 0.4 0.55 0.55 0.41 – 0.36 0.36 0.6 0.7 0.76 0.65 0.68 0.67
Cytoplasm 0.68 0.55 0.46 0.5 0.51 0.47 0.47 0.42 0.4 0.39 0.34 0.35 0.62 0.62 0.76 – 0.67 0.66 0.1 0.07 0 0.08 0.05 0.08
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0.07 0.08 0.05 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0.05 0.05 0.12 0.24 0.22 0.46 0.41 0.46 0.54 0.55 0.57 0.57 0 0 0 – 0 0.09 0 0 0 0.05 0.06 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0.07 0.07 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 – 0.05 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 23 63 69 26 37 32 33 39 36 57 55 39 37 39 34 – 19 8 29 35 39 24 25 22
Bud 4 21 17 15 9 9 14 30 20 28 19 23 13 13 9 – 2 3 3 2 0 0 3 7
Bud Neck 1 0 3 0 0 0 0 1 0 0 0 0 8 8 1 – 3 6 14 29 12 13 18 19
Bud Site 0 0 1 0 1 1 0 2 0 0 0 1 0 0 0 – 0 0 – – – – – –
Cell Periphery 77 201 158 92 103 82 113 92 114 163 110 190 413 413 292 – 90 57 154 307 288 175 235 241
Cytoplasm 144 205 147 107 123 110 160 127 133 169 117 164 470 470 542 – 166 104 25 29 6 23 18 27
Endoplasmic Reticulum 2 4 2 4 3 5 7 5 3 6 14 11 11 7 5 – 18 13 13 11 12 9 8 14
Endosome 1 0 0 0 1 0 1 1 1 0 0 1 1 1 0 – 2 2 2 1 2 1 1 2
Golgi 3 2 1 0 0 0 0 0 0 0 0 0 0 0 0 – 1 1 2 2 0 1 0 0
Mitochondria 10 18 39 51 53 108 140 139 181 240 194 269 0 0 0 – 11 14 7 11 8 14 20 12
Nucleus 0 0 0 0 0 0 0 2 2 2 1 1 0 0 1 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 1 1 1 2 1 1 0 1 0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 12 16 16 8 11 5 5 9 1 10 0 0 0 – 0 2 0 0 1 0 0 0
SpindlePole 2 2 16 5 5 0 4 4 0 2 3 1 13 12 4 – 12 3 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 3 2 0 1 2 1 1 1 1 0 0 2 – 2 0 2 6 1 4 8 4
Unique Cell Count 213 373 323 214 243 235 340 304 335 438 341 474 755 754 716 249 157 259 440 378 271 345 360
Labelled Cell Count 267 516 465 319 354 356 485 451 499 678 516 712 966 963 890 326 213 259 440 378 271 345 360


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.4 5.8 5.3 5.2 5.5 4.9 5.1 5.3 5.2 4.9 5.1 5.2 6.7 6.7 6.8 4.8 5.6 6.5 6.2 6.4 6.8
Std Deviation (1e-4) 0.8 0.7 1.1 1.2 1.5 1.1 1.3 1.1 1.0 0.9 1.1 0.7 0.8 0.8 0.9 1.0 1.2 2.2 1.0 1.3 1.5
Intensity Change (Log2) – – – -0.04 0.05 -0.11 -0.04 0.0 -0.04 -0.1 -0.06 -0.02 0.34 0.34 0.36 -0.13 0.07 0.31 0.23 0.27 0.36


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -2.7 -1.9 -2.3 -4.2 -2.8 -3.7 -3.1 -1.7 -5.3 -8.3 -8.1 -8.3 – -4.5 -4.6
Bud 0.8 -0.9 -0.8 -0.7 2.2 0.4 0.7 0.2 -0.3 -3.2 -3.2 -3.8 – -3.0 -1.7
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Cell Periphery -1.3 -1.5 -3.3 -4.1 -4.8 -3.9 -3.2 -4.4 -2.5 1.7 1.8 -2.4 – -3.1 -2.6
Cytoplasm 1.0 1.2 0.3 0.4 -0.9 -1.5 -1.9 -2.9 -3.1 5.1 5.1 9.5 – 5.0 4.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 2.9 1.9 0 0 0 – 4.3 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Mitochondria 3.6 3.1 9.0 8.4 9.3 11.4 12.1 12.1 12.7 -9.7 -9.7 -9.5 – -3.2 -1.0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Peroxisomes 1.9 1.6 -0.2 -0.3 -1.6 -1.8 -1.4 -3.2 -1.4 0 0 0 – -3.1 0
SpindlePole -1.5 -1.8 -3.5 -2.8 -2.6 -4.1 -4.0 -3.1 -4.5 -3.0 -3.2 -4.8 – -0.1 -1.6
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.8583 3.3442 3.1859 3.0275 2.9249 3.1554 3.5042 4.7827 4.833 3.9339 4.7445 4.5247 4.643 4.8481 4.068 5.1305 4.365 4.1476
Actin 0.0518 0.007 0.0162 0.0011 0.025 0.004 0.0157 0.0061 0.0222 0.0001 0.0021 0.0003 0.1388 0.0017 0.0122 0.0004 0.0691 0.0156
Bud 0.012 0.0009 0.0102 0.0007 0.0013 0.0022 0.0011 0.0004 0.0007 0.0002 0.0003 0.0003 0.001 0.0005 0.0038 0.0002 0.0006 0.001
Bud Neck 0.0092 0.0043 0.0187 0.014 0.0044 0.0067 0.017 0.0034 0.0063 0.0015 0.0065 0.003 0.0068 0.0056 0.0116 0.0014 0.0018 0.01
Bud Periphery 0.0307 0.0067 0.014 0.0145 0.0259 0.0127 0.0061 0.0033 0.0066 0.0046 0.0067 0.0059 0.0029 0.0022 0.0322 0.0035 0.0021 0.0108
Bud Site 0.0236 0.0729 0.0615 0.0062 0.0036 0.0043 0.0246 0.0903 0.0257 0.0009 0.0036 0.001 0.0058 0.0645 0.0589 0.0016 0.0046 0.0036
Cell Periphery 0.4019 0.3918 0.4425 0.6161 0.572 0.5359 0.593 0.4598 0.4726 0.7106 0.4463 0.6279 0.1637 0.3432 0.497 0.3075 0.6641 0.4503
Cytoplasm 0.2584 0.4563 0.3631 0.3268 0.3126 0.3673 0.2403 0.3371 0.3284 0.2788 0.3135 0.31 0.3847 0.4564 0.273 0.6002 0.1847 0.4091
Cytoplasmic Foci 0.012 0.0016 0.0046 0.0008 0.0039 0.0032 0.0027 0.0012 0.0014 0 0.0012 0.0003 0.04 0.0029 0.005 0.0016 0.0181 0.0028
Eisosomes 0.0055 0.0073 0.0042 0.0014 0.0021 0.0013 0.0117 0.0042 0.0071 0.0003 0.0073 0.0007 0.003 0.0008 0.0022 0.0005 0.0003 0.0011
Endoplasmic Reticulum 0.0146 0.0103 0.0102 0.0073 0.0127 0.0094 0.003 0.0028 0.0036 0.0014 0.0111 0.0016 0.0301 0.005 0.0077 0.009 0.0024 0.0033
Endosome 0.019 0.0003 0.0046 0.0001 0.0044 0.0008 0.0011 0.0001 0.0002 0 0.0001 0 0.0644 0.0097 0.0408 0.0004 0.0092 0.0193
Golgi 0.0057 0.001 0.0036 0.0002 0.0091 0.001 0.0011 0.0003 0.0007 0 0.0004 0.0001 0.0135 0.0011 0.0015 0.0002 0.0166 0.0014
Lipid Particles 0.0067 0.0042 0.004 0.0005 0.0116 0.0054 0.002 0.0015 0.0008 0.0001 0.0014 0.0004 0.0072 0.0015 0.0016 0.0016 0.0067 0.0021
Mitochondria 0.0053 0.0003 0.003 0.0002 0.0016 0.0002 0.0002 0 0.0002 0 0.0002 0 0.0045 0.001 0.0009 0.0001 0.003 0.0002
None 0.1054 0.0323 0.028 0.0066 0.0015 0.0363 0.0752 0.087 0.1199 0.0004 0.1943 0.0456 0.0216 0.0758 0.0046 0.0653 0.0027 0.0388
Nuclear Periphery 0.0096 0.0003 0.0014 0.0002 0.0006 0.0003 0.0003 0.0002 0.0002 0.0001 0.0003 0.0001 0.009 0.0013 0.0006 0.0003 0.0003 0.0005
Nucleolus 0.0017 0.0002 0.0006 0.0001 0.0001 0.0003 0.0003 0.0002 0.0004 0 0.0006 0 0.0009 0.0005 0.0002 0.0001 0.0001 0.0001
Nucleus 0.0079 0.0004 0.0016 0.0003 0.0003 0.0005 0.0003 0.0002 0.0004 0 0.0007 0.0001 0.0026 0.0012 0.0007 0.0004 0.0002 0.0005
Peroxisomes 0.0025 0.0001 0.0016 0 0.0031 0.0036 0.0003 0 0.0005 0 0 0 0.0027 0.0001 0.0002 0 0.0106 0.0001
Punctate Nuclear 0.0057 0.0001 0.0023 0 0.0005 0.0004 0.0003 0.0001 0.0001 0 0.0001 0 0.0298 0.0002 0.0001 0.0001 0.0009 0.0002
Vacuole 0.0096 0.0018 0.0041 0.0029 0.0034 0.0041 0.0036 0.0016 0.0019 0.0011 0.0031 0.0027 0.0605 0.0242 0.0395 0.0056 0.0016 0.0204
Vacuole Periphery 0.0012 0 0.0003 0 0.0002 0.0001 0.0001 0 0 0 0 0 0.0063 0.0007 0.0054 0 0.0001 0.0086

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 53.6628 40.9643 36.3967 45.0153 50.4232 42.1834 42.6451 46.7142 38.6887 52.0269
Translational Efficiency 0.4501 0.4918 0.4818 0.3399 0.3447 0.4658 0.4366 0.3209 0.3595 0.328

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
138 395 156 1145 2281 1677 1961 1563 2419 2072 2117 2708

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 878.66 816.07 941.26 913.02 726.19 785.70 856.44 892.77 734.89 791.49 862.69 901.33
Standard Deviation 133.76 97.04 101.90 111.72 86.60 102.59 113.47 120.48 96.66 102.25 114.82 117.28
Intensity Change Log 2 — -0.106612 0.099288 0.055341 — 0.113631 0.238005 0.297941 — -0.002771 0.163714 0.170192

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000410 0.025971 0.001297 0.006492 0.008421 0.013738 0.000922 0.004160 0.007964 0.016070 0.000950 0.005146
Bud Neck 0.006815 0.092365 0.004914 0.016303 0.068897 0.094913 0.017822 0.017107 0.065355 0.094427 0.016871 0.016767
Bud Site 0.035361 0.068242 0.018730 0.065990 0.027476 0.038928 0.025713 0.052286 0.027926 0.044517 0.025198 0.058080
Cell Periphery 0.000534 0.081951 0.000987 0.003361 0.036635 0.042015 0.000995 0.001241 0.034575 0.049628 0.000995 0.002138
Cytoplasm 0.280429* 0.456529* 0.273174* 0.301221* 0.582328* 0.542775* 0.508218* 0.410193* 0.565105* 0.526333* 0.490898* 0.364117*
Cytoplasmic Foci 0.087303 0.078050 0.077732 0.043636 0.051303 0.068217 0.038000 0.053456 0.053356 0.070091 0.040928 0.049304
Eisosomes 0.000242 0.051825 0.000306 0.001434 0.069997 0.059222 0.000266 0.000724 0.066017 0.057812 0.000269 0.001024
Endoplasmic Reticulum 0.003369 0.003798 0.012499 0.006199 0.004498 0.003740 0.004827 0.003486 0.004434 0.003751 0.005393 0.004633
Endosome 0.021617 0.007648 0.016493 0.012444 0.003351 0.007464 0.003747 0.013296 0.004393 0.007499 0.004686 0.012936
Golgi 0.010662 0.012531 0.000310 0.004187 0.014321 0.016854 0.000470 0.005816 0.014112 0.016030 0.000458 0.005127
Lipid Particles 0.003441 0.007033 0.009212 0.004630 0.012007 0.010818 0.003550 0.004111 0.011518 0.010096 0.003967 0.004330
Mitochondria 0.000506 0.005289 0.000662 0.002186 0.007474 0.009984 0.000413 0.003688 0.007076 0.009089 0.000431 0.003053
Mitotic Spindle 0.001107 0.000965 0.000626 0.011845 0.000583 0.000940 0.000768 0.010683 0.000613 0.000944 0.000757 0.011174
None 0.000465 0.000283 0.000937 0.000465 0.002872 0.000785 0.000800 0.000954 0.002734 0.000689 0.000810 0.000747
Nuclear Periphery 0.000494 0.000078 0.001446 0.000850 0.000114 0.000114 0.000589 0.000297 0.000136 0.000107 0.000652 0.000531
Nuclear Periphery Foci 0.001574 0.001245 0.012769 0.003346 0.000294 0.000264 0.002332 0.001924 0.000367 0.000451 0.003101 0.002525
Nucleolus 0.000260 0.000120 0.000543 0.000154 0.000271 0.000199 0.000210 0.000165 0.000271 0.000184 0.000234 0.000160
Nucleus 0.100908 0.047081 0.199754* 0.056060 0.075890 0.043407 0.196777* 0.057964 0.077317 0.044107 0.196996* 0.057159
Peroxisomes 0.001184 0.012324 0.001549 0.004778 0.011703 0.014775 0.000725 0.005354 0.011103 0.014307 0.000786 0.005110
Vacuole 0.434061* 0.046178 0.365670* 0.451842* 0.021201 0.029583 0.192357 0.350716* 0.044754 0.032747 0.205128* 0.393474*
Vacuole Periphery 0.009260 0.000495 0.000389 0.002579 0.000365 0.001267 0.000500 0.002378 0.000873 0.001120 0.000492 0.002463

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.71 -4.40 -7.49 6.25 -5.44 -4.81 14.07 6.18 8.95 -3.84 -7.18 13.90 5.94 10.88 -6.78
Bud Neck -12.25 0.46 -4.08 11.41 -6.70 -6.26 20.11 22.09 22.30 1.70 -7.68 20.11 22.80 25.38 1.86
Bud Site -3.52 1.22 -2.31 2.20 -5.59 -5.03 1.74 -4.64 -1.15 -5.31 -7.18 2.04 -7.04 -0.78 -7.75
Cell Periphery -9.87 -3.80 -4.52 9.62 -3.38 -1.84 21.40 21.34 17.16 -0.52 -5.06 21.25 20.72 19.05 -3.21
Cytoplasm -7.91 0.37 -1.49 11.52 -2.33 5.79 14.30 23.33 16.75 9.36 5.65 14.04 31.61 24.16 14.28
Cytoplasmic Foci 0.12 1.44 5.15 6.85 3.81 -5.18 5.44 1.04 5.86 -4.06 -5.68 5.42 4.05 9.38 -1.80
Eisosomes -11.90 -1.56 -6.09 11.71 -5.75 3.68 35.33* 35.15* 26.96 -5.61 3.04 34.79 34.50 29.31 -8.04
Endoplasmic Reticulum -0.97 -7.21 -2.24 -1.97 6.49 1.01 -1.06 2.51 1.03 4.11 1.00 -2.39 0.95 -0.27 4.03
Endosome 2.63 0.60 2.55 -0.55 4.06 -7.39 -0.85 -8.08 -2.88 -7.70 -5.39 -0.86 -7.78 -2.55 -7.43
Golgi -0.90 1.48 1.01 5.47 -3.21 -2.47 20.27 9.12 10.51 -3.90 -2.12 19.16 11.52 13.32 -4.76
Lipid Particles -4.66 -6.38 -1.08 4.77 6.66 1.62 14.37 13.02 11.63 0.01 2.12 13.49 13.90 13.08 0.85
Mitochondria -4.03 -0.47 -2.18 2.99 -1.76 -2.12 11.83 4.99 5.74 -2.95 -1.96 11.78 6.65 7.04 -3.64
Mitotic Spindle 0.44 0.66 -4.03 -4.12 -4.54 -0.86 -0.67 -5.01 -4.79 -4.92 -0.78 -0.56 -6.81 -6.50 -6.74
None 0.75 -2.54 -1.08 -2.30 1.59 6.93 7.25 4.91 -0.28 -0.34 7.29 7.14 6.22 -0.27 0.17
Nuclear Periphery 6.12 -8.88 -1.09 -2.63 2.67 -0.01 -18.47 -8.60 -7.61 6.82 1.89 -20.28 -3.59 -3.81 1.50
Nuclear Periphery Foci 0.48 -10.14 -2.47 -1.82 9.46 1.29 -12.01 -9.76 -10.00 2.76 -0.48 -14.69 -13.35 -8.52 4.09
Nucleolus 2.81 -3.51 2.48 -0.73 4.94 3.49 1.54 6.23 1.88 2.43 4.61 0.67 7.49 2.04 3.96
Nucleus 2.91 -5.88 1.68 -3.37 8.35 12.57 -26.36 4.23 -6.56 28.03 12.82 -26.98 4.96 -7.86 30.39
Peroxisomes -7.78 -0.55 -2.67 5.57 -2.26 -2.85 17.80 7.55 8.84 -4.97 -3.33 17.68 9.03 10.91 -5.79
Vacuole 16.04 2.81 0.13 -47.09 -4.13 -5.89 -39.71 -50.73 -49.05 -19.39 5.01 -32.47 -60.89 -69.08* -26.60
Vacuole Periphery 1.31 1.34 1.07 -2.24 -2.52 -2.15 -0.22 -2.82 -0.66 -2.52 -0.90 0.99 -2.13 -1.12 -3.25
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Myo-inositol transporter; member of the sugar transporter superfamily; expressed constitutively; ITR2 has a paralog, ITR1, that arose from the whole genome duplication
Localization
Cell Percentages cell periphery (28%), cytoplasm (3%), mixed (52%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Itr2

Itr2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Itr2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available