Standard name
Human Ortholog
Description Cytochrome c1; component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.12 0.05 0.13 0.09 0.08 0 0.06 0 0.08
Bud 0 0 0 0 0 0 0 0 – 0 0 0.05 0 0 0 0 0.07 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.29 0 0 0 0 0 0 0 0
Cytoplasm 0.06 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0.1 0.09 0 0 0 0 0 0 0 0 0
Golgi 0.05 0 0 0 0 0 0 0 – 0 0 0 0.21 0.26 0.25 0.47 0.33 0.29 0.07 0.11 0.06 0.1 0.15 0.13
Mitochondria 0.73 0.92 0.92 0.96 0.9 0.87 0.88 0.87 – 0.91 0.93 0.91 0.78 0.74 0.65 0 0.07 0.16 0.66 0.68 0.68 0.6 0.57 0.55
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0.07 0.09 0.08 – 0.08 0.08 0.08 0 0 0 0.06 0.05 0.08 0 0 0 0 0 0
Nucleolus 0.12 0 0.05 0 0.07 0.12 0.13 0.15 – 0.12 0.12 0.14 0 0 0 0 0.05 0 0 0 0 0 0 0
Peroxisomes 0 0.06 0.2 0 0 0 0 0 – 0 0 0 0.11 0 0.09 0.12 0.22 0.08 0 0.05 0.19 0.15 0.16 0.12
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Vac/Vac Membrane 0.08 0.09 0 0 0.09 0 0 0 – 0 0 0 0.1 0.12 0.18 0.12 0.14 0.24 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 3 0 1 0 1 0 3 – 1 0 0 2 1 3 2 3 5 6 29 6 8 7 14
Bud 0 5 8 2 6 14 14 13 – 5 10 17 1 2 2 0 4 2 0 1 0 0 0 3
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Bud Site 0 1 0 0 0 6 5 2 – 6 6 2 1 0 0 0 0 0 – – – – – –
Cell Periphery 2 15 3 2 3 0 1 1 – 1 1 0 3 3 7 5 2 1 0 2 0 0 0 0
Cytoplasm 4 3 4 1 2 6 6 4 – 3 2 6 3 3 1 1 1 0 0 2 0 0 0 0
Endoplasmic Reticulum 1 1 0 0 1 11 5 4 – 4 6 2 0 3 0 0 0 0 0 0 0 0 0 0
Endosome 1 1 6 3 7 0 3 4 – 2 0 1 6 14 19 0 1 1 0 12 10 5 6 5
Golgi 3 15 0 2 1 2 0 0 – 0 2 1 29 37 51 8 19 11 5 38 16 14 25 26
Mitochondria 47 316 250 151 219 318 426 525 – 410 334 341 107 106 136 0 4 6 48 253 192 86 99 106
Nucleus 0 0 0 0 0 3 3 4 – 4 0 0 0 0 2 0 3 0 0 0 0 0 0 0
Nuclear Periphery 1 10 11 3 10 24 44 46 – 37 28 31 2 3 3 1 3 3 1 1 0 1 2 2
Nucleolus 8 5 14 5 18 44 65 88 – 54 42 52 5 2 5 0 3 1 1 0 0 1 0 1
Peroxisomes 0 20 55 7 8 4 19 15 – 12 5 5 15 6 18 2 13 3 1 20 53 21 27 22
SpindlePole 2 1 4 2 0 1 8 6 – 9 3 1 2 1 7 0 3 0 2 0 0 1 0 0
Vac/Vac Membrane 5 30 4 4 22 7 7 14 – 10 5 6 14 17 38 2 8 9 0 3 0 1 1 7
Unique Cell Count 64 343 273 158 243 366 483 605 453 361 373 137 143 208 17 58 38 74 370 285 144 175 195
Labelled Cell Count 74 426 359 183 297 441 606 729 558 444 465 190 198 292 21 67 42 74 370 285 144 175 195


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 18.4 14.4 9.6 9.8 9.3 9.3 9.1 10.0 – 10.3 11.2 11.6 10.6 10.6 10.2 14.7 14.0 14.6 12.3 12.9 13.0
Std Deviation (1e-4) 8.6 3.9 2.9 4.6 3.3 3.6 3.5 3.8 – 4.3 4.7 4.5 2.7 2.8 4.6 3.7 3.8 3.9 3.6 4.4 3.9
Intensity Change (Log2) – – – 0.03 -0.04 -0.04 -0.08 0.07 – 0.1 0.22 0.27 0.14 0.14 0.1 0.62 0.55 0.61 0.36 0.43 0.45

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP70001020WT3HU80HU120HU16001020WT3rpd3Δ_1rpd3Δ_2rpd3Δ_301020WT1AF100AF140AF18001020
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 -0.3 0.6 0 -0.7 – 0 -0.1 1.1 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome 0 0.5 0 0 0 – 0 0 0 0 3.4 3.4 0 0 0
Golgi 0 0 0 0 0 – 0 0 0 7.9 8.8 8.7 0 0 0
Mitochondria 1.6 -0.6 -1.9 -1.4 -2.0 – -0.5 0.4 -0.1 -3.8 -4.8 -7.1 -10.6 -13.9 -11.5
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery -1.2 0 1.4 2.6 2.0 – 2.2 1.9 2.2 0 0 -1.7 0 0 0
Nucleolus -1.0 1.1 3.0 3.6 4.0 – 3.0 2.9 3.7 -0.7 -1.9 -1.5 0 0 0
Peroxisomes -4.5 -5.8 -8.2 -7.2 -8.9 – -7.9 -8.0 -8.1 -2.3 -4.4 -3.5 0 0.4 -1.8
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 0 3.9 0 0 0.8 – 0.7 0 0 4.1 4.6 6.5 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 11.1776 12.1125 11.6069 9.9511 10.705 11.1356 20.5656 18.6902 19.8332 20.0645 18.5859 18.9104 18.2679 16.5956 18.7008 16.5511 18.0826 17.5973
Actin 0.0159 0.03 0.0186 0.008 0.027 0.0066 0.0121 0.0126 0.0128 0.0004 0.0015 0.0033 0.0099 0.0091 0.0034 0.0167 0.0027 0.0109
Bud 0.0002 0.0011 0.0006 0.0002 0.0005 0.0008 0 0 0 0 0 0 0 0.0001 0 0 0 0
Bud Neck 0.0003 0.0003 0.0003 0.0001 0.0004 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Periphery 0.0004 0.0012 0.0014 0.0004 0.002 0.0033 0.0001 0.0001 0 0 0 0 0.0001 0.0001 0 0 0 0
Bud Site 0.001 0.0033 0.0076 0.0009 0.0007 0.0001 0.0001 0.0001 0.0001 0 0 0 0.0001 0.0001 0 0 0 0
Cell Periphery 0.0002 0.0003 0.0002 0.0001 0.0006 0.0001 0.0001 0.0001 0 0 0 0 0.0001 0.0001 0.0001 0 0 0.0001
Cytoplasm 0.0013 0.0002 0.0015 0.0006 0.0002 0 0 0 0.0001 0 0 0 0 0 0 0 0 0
Cytoplasmic Foci 0.0133 0.0088 0.0065 0.0106 0.0109 0.0017 0.0016 0.0023 0.001 0.0001 0.0011 0.0003 0.001 0.0025 0.0011 0.0006 0.0001 0.001
Eisosomes 0.0005 0.0006 0.0006 0.0004 0.0003 0.0004 0.0009 0.0003 0.0003 0.0002 0.0004 0.0005 0.0009 0.0003 0.0004 0.0006 0.001 0.0005
Endoplasmic Reticulum 0.0019 0.0002 0.0004 0.0003 0.0002 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.0201 0.0166 0.0075 0.026 0.0159 0.0038 0.0017 0.006 0.0012 0.0001 0.0026 0.0014 0.0026 0.0078 0.0028 0.0036 0.0011 0.0028
Golgi 0.043 0.0709 0.0557 0.1123 0.0668 0.0315 0.0139 0.0446 0.0069 0.0012 0.0227 0.0224 0.0209 0.0405 0.0237 0.0191 0.016 0.0332
Lipid Particles 0.0325 0.0135 0.0167 0.019 0.0272 0.0144 0.0142 0.0053 0.0038 0.0004 0.0202 0.0014 0.0161 0.0199 0.016 0.0027 0.0004 0.0126
Mitochondria 0.7951 0.8174 0.8498 0.7827 0.8166 0.9144 0.9346 0.8913 0.9628 0.9925 0.9367 0.9658 0.9328 0.9008 0.9435 0.9228 0.9761 0.9212
None 0.0005 0 0.0002 0.0003 0.0001 0 0 0 0.0001 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.0077 0.0001 0.0034 0.0003 0.0003 0 0.0001 0 0.0001 0 0 0 0.0001 0 0 0 0 0
Nucleolus 0.0045 0.0003 0.0005 0.0001 0.0001 0.0002 0.0003 0 0 0 0 0 0.0004 0 0 0 0 0
Nucleus 0.0015 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0 0 0 0 0 0.0001 0 0 0 0 0
Peroxisomes 0.0433 0.0285 0.0227 0.0311 0.018 0.0198 0.014 0.0333 0.0079 0.005 0.0126 0.0041 0.0096 0.0134 0.004 0.0307 0.0017 0.0099
Punctate Nuclear 0.0043 0 0.0002 0.0005 0.0002 0 0.0001 0 0.0011 0 0 0 0 0 0 0 0 0
Vacuole 0.0045 0.0018 0.001 0.0015 0.0027 0.0006 0.0011 0.0006 0.0003 0 0.0002 0.0001 0.0009 0.0005 0.0006 0.0003 0.0001 0.0005
Vacuole Periphery 0.0079 0.0049 0.0044 0.0044 0.0091 0.0023 0.0053 0.0035 0.0015 0.0001 0.0018 0.0006 0.0043 0.0048 0.0041 0.0028 0.0009 0.007

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 24.3224 14.8487 20.4627 41.8909 26.151 29.645 26.0055 26.7803 33.4365 22.2665
Translational Efficiency 1.2112 1.6758 1.8003 1.3819 1.4049 1.054 1.053 1.6765 1.4155 1.2344

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1696 2126 1606 1697 2434 1895 2715 1978 4130 4021 4321 3675

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 917.45 998.00 1717.81 1388.46 821.49 999.40 1447.93 1421.36 860.90 998.66 1548.24 1406.17
Standard Deviation 235.13 226.53 487.93 314.68 150.30 251.13 318.87 331.98 195.56 238.44 411.56 324.52
Intensity Change Log 2 — 0.121410 0.904869 0.597784 — 0.282819 0.817677 0.790957 — 0.199915 0.864335 0.692270

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.015292 0.020813 0.004930 0.010251 0.017356 0.019387 0.002115 0.006925 0.016509 0.020141 0.003161 0.008461
Bud Neck 0.001355 0.000938 0.001565 0.000767 0.001896 0.000878 0.000830 0.001490 0.001674 0.000910 0.001103 0.001156
Bud Site 0.002484 0.003623 0.001352 0.003917 0.006508 0.001592 0.001520 0.010479 0.004856 0.002666 0.001457 0.007449
Cell Periphery 0.000266 0.000215 0.000114 0.000362 0.000518 0.000146 0.000085 0.000714 0.000414 0.000183 0.000096 0.000552
Cytoplasm 0.000938 0.000905 0.000336 0.000786 0.002893 0.000636 0.000538 0.001653 0.002090 0.000778 0.000463 0.001253
Cytoplasmic Foci 0.020540 0.015575 0.011074 0.007705 0.040565 0.025582 0.007432 0.008226 0.032342 0.020291 0.008786 0.007985
Eisosomes 0.000613 0.000592 0.000627 0.000249 0.000248 0.000668 0.000161 0.000288 0.000398 0.000628 0.000335 0.000270
Endoplasmic Reticulum 0.000263 0.000153 0.000117 0.000473 0.000248 0.000206 0.000084 0.000426 0.000255 0.000178 0.000096 0.000448
Endosome 0.020962 0.015190 0.002124 0.008038 0.069418 0.016580 0.005453 0.015004 0.049519 0.015845 0.004216 0.011787
Golgi 0.048633 0.042511 0.017836 0.050903 0.069946 0.064773 0.018305 0.034556 0.061194 0.053002 0.018131 0.042105
Lipid Particles 0.024200 0.007302 0.006223 0.001002 0.018302 0.013001 0.003210 0.002841 0.020724 0.009988 0.004330 0.001992
Mitochondria 0.816419 0.841586 0.915856 0.888221 0.667140 0.813728 0.938805 0.879576 0.728442 0.828457 0.930275 0.883568
Mitotic Spindle 0.001153 0.001538 0.001781 0.003943 0.003644 0.001169 0.002600 0.003300 0.002621 0.001364 0.002296 0.003597
None 0.001150 0.000492 0.003933 0.000755 0.000533 0.000643 0.001116 0.000808 0.000786 0.000563 0.002163 0.000783
Nuclear Periphery 0.000192 0.000089 0.001122 0.000170 0.000061 0.000119 0.000498 0.000791 0.000115 0.000103 0.000730 0.000504
Nuclear Periphery Foci 0.000179 0.000095 0.000377 0.000110 0.000161 0.000171 0.000191 0.000430 0.000168 0.000131 0.000260 0.000282
Nucleolus 0.000124 0.000058 0.000560 0.000082 0.000215 0.000079 0.000194 0.000155 0.000178 0.000068 0.000330 0.000122
Nucleus 0.000077 0.000073 0.000093 0.000028 0.000118 0.000030 0.000055 0.000102 0.000101 0.000053 0.000069 0.000068
Peroxisomes 0.041242 0.045900 0.004204 0.005402 0.096911 0.037162 0.005041 0.008277 0.074050 0.041782 0.004730 0.006949
Vacuole 0.001418 0.001033 0.006794 0.006581 0.001751 0.001532 0.004441 0.011017 0.001614 0.001268 0.005316 0.008969
Vacuole Periphery 0.002499 0.001320 0.018982 0.010255 0.001569 0.001920 0.007327 0.012940 0.001951 0.001603 0.011659 0.011700

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.44 5.85 2.43 5.02 -3.40 -0.96 11.12 6.45 6.58 -5.09 -2.35 12.36 6.24 8.32 -6.15
Bud Neck 1.22 -0.61 1.66 0.71 3.23 3.26 3.55 1.22 -2.70 -3.13 3.30 2.42 2.13 -1.67 -0.35
Bud Site -1.13 1.59 -1.66 -0.40 -3.50 5.50 5.50 -2.47 -6.25 -6.26 3.09 5.57 -2.70 -5.23 -7.08
Cell Periphery 1.13 3.79 -1.37 -2.28 -4.05 4.75 5.55 -1.22 -4.02 -4.45 4.62 6.52 -1.46 -4.50 -5.62
Cytoplasm 0.15 2.40 0.61 0.69 -2.61 4.39 3.96 2.10 -3.40 -2.63 4.10 4.38 2.34 -2.68 -3.06
Cytoplasmic Foci 3.19 6.05 9.34 6.16 2.65 7.05 19.70 18.63 10.72 -0.84 8.82 19.91 20.72 12.04 1.08
Eisosomes 0.26 -0.17 5.54 6.23 6.32 -5.94 4.56 -1.26 5.06 -4.01 -4.60 1.81 3.92 7.76 2.22
Endoplasmic Reticulum 2.49 3.55 -1.98 -3.20 -3.61 1.22 5.45 -2.71 -3.55 -5.78 2.80 6.44 -3.21 -4.75 -6.33
Endosome 2.98 11.63 7.20 5.18 -6.71 18.88 24.38 18.82 0.89 -6.70 18.08 26.23 20.12 3.58 -8.57
Golgi 1.72 10.01 -0.52 -2.03 -8.83 1.28 17.86 10.13 7.61 -5.88 3.04 20.20 6.89 3.86 -10.47
Lipid Particles 7.45 7.96 10.94 7.56 6.45 2.72 9.43 9.55 7.78 0.57 7.42 12.42 14.55 10.41 4.86
Mitochondria -2.82 -12.14 -8.02 -5.79 3.88 -15.06 -34.48 -23.41 -7.67 9.35 -14.76 -34.58 -23.64 -9.39 9.94
Mitotic Spindle -1.02 -1.58 -3.68 -3.07 -2.60 5.15 1.50 0.48 -3.68 -0.90 3.76 0.64 -1.88 -4.63 -2.24
None 3.32 -9.90 1.98 -5.85 15.55 -0.42 -2.29 -1.09 -2.60 4.00 1.35 -7.35 0.03 -5.70 15.00
Nuclear Periphery 2.11 -3.84 0.41 -3.33 3.98 -4.02 -5.22 -2.51 -2.31 -0.97 0.54 -5.87 -2.46 -2.55 1.20
Nuclear Periphery Foci 1.94 -2.94 1.83 -0.52 4.54 -0.06 -0.74 -2.62 -2.14 -2.39 0.96 -2.69 -1.95 -2.36 -0.38
Nucleolus 1.95 -4.88 1.14 -1.03 5.54 1.90 0.52 0.99 -2.72 0.96 2.40 -2.15 1.34 -2.90 5.10
Nucleus 0.09 -0.57 1.99 1.35 2.24 3.85 2.17 0.67 -3.51 -1.62 2.12 1.31 1.75 -0.77 0.26
Peroxisomes -1.12 12.00 11.54 13.65 -1.14 12.91 23.83 22.35 9.96 -2.40 9.94 26.28 24.98 16.63 -2.52
Vacuole 1.24 -6.82 -5.07 -5.49 0.16 0.73 -5.29 -8.65 -8.74 -5.64 1.63 -8.52 -9.88 -10.30 -4.34
Vacuole Periphery 4.22 -11.01 -7.42 -8.72 4.86 -1.99 -9.66 -10.90 -10.50 -4.70 2.28 -14.33 -13.18 -13.71 -0.05
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cytochrome c1; component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex
Localization
Cell Percentages mitochondrion (93%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Cyt1

Cyt1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cyt1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available