Standard name
Human Ortholog
Description Protein involved in proteolytic activation of Rim101p; part of response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.98 0.94 0.95 0.93 0.88 0.91 0.82 0.73 0.71 0.64 0.71 0.98 0.97 0.98 0.84 0.9 0.85 0.84 0.92 0.71 0.92 0.91 0.89
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.05 0.07 0.08 0.22 0.18 0.38 0.22 0 0 0 0 0 0 0 0 0.06 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.05 0.09 0.12 0.12 0.05 0.08 0 0 0 0.15 0.05 0.15 0 0 0.05 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 1 2 0 4 0 3 2 1 1 2 1 3 7 4 15 5 2 4 10 9
Bud 2 1 0 0 2 1 2 4 1 7 4 6 2 0 0 0 2 0 1 1 0 0 2 2
Bud Neck 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 3 4 0 0 2 2
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 7 0 0 2 1 2 1 1 0 1 1 0 2 0 4 4 4 0 0 0 0 0 0
Cytoplasm 320 371 34 71 193 213 294 369 142 160 129 197 308 524 739 397 251 289 300 359 63 206 453 566
Endoplasmic Reticulum 0 4 0 1 1 8 3 9 4 1 3 5 4 5 0 19 10 10 4 0 1 0 0 2
Endosome 5 1 2 0 5 9 1 3 2 4 1 4 1 6 5 21 8 12 11 4 4 4 11 17
Golgi 0 1 0 0 0 0 1 2 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0
Mitochondria 3 1 0 1 2 11 22 38 43 41 77 62 0 1 0 3 2 2 3 2 5 1 4 4
Nucleus 0 0 0 0 1 6 4 8 4 8 6 13 0 2 0 7 5 7 0 0 0 0 0 1
Nuclear Periphery 0 0 0 0 0 0 0 1 1 2 0 0 1 0 0 1 0 0 0 0 1 0 0 0
Nucleolus 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 1 1 1 0 0 0 0 0 0
Peroxisomes 1 0 0 0 0 2 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0
SpindlePole 1 0 1 2 4 1 1 3 0 3 3 0 1 2 2 3 1 7 6 0 2 1 8 15
Vac/Vac Membrane 2 4 0 1 5 10 16 42 23 26 11 21 3 4 10 73 15 51 8 3 4 2 2 6
Unique Cell Count 331 379 36 75 207 242 323 449 194 225 202 277 315 538 752 474 278 342 359 390 90 224 499 636
Labelled Cell Count 338 390 37 76 216 265 346 484 222 255 238 310 322 548 757 533 306 387 359 390 90 224 499 636


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.5 6.7 7.1 6.5 7.3 6.4 6.2 6.5 6.0 5.8 5.3 5.3 7.0 7.0 7.0 8.8 8.4 7.9 6.4 6.7 7.1
Std Deviation (1e-4) 0.5 0.8 0.9 1.5 1.4 1.4 1.4 1.3 5.5 1.5 5.9 1.3 0.9 0.9 0.9 1.8 1.4 1.7 0.8 0.9 1.1
Intensity Change (Log2) – – – -0.14 0.04 -0.16 -0.2 -0.13 -0.26 -0.29 -0.42 -0.42 -0.02 -0.03 -0.02 0.3 0.23 0.15 -0.16 -0.08 0.0


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 -0.3 -1.1 -0.7 -1.9 -2.8 -3.0 -3.6 -3.0 1.2 1.0 1.6 -1.7 -0.8 -1.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 3.1 2.8 4.5 3.2 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 2.5 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.5161 1.4266 1.1645 1.231 0.9047 1.1412 0.623 1.703 1.5022 0.7054 0.9446 1.5491 0.13 0.6507 0.5445 0.2838 0.1834 0.4897
Actin 0.0477 0.0117 0.0119 0.0018 0.0005 0.0016 0.0019 0.0003 0.0066 0.0032 0.0014 0.0008 0.0394 0.0009 0.012 0.0263 0.0001 0.0126
Bud 0.0014 0.0005 0.0008 0.0007 0 0.0001 0.0033 0.005 0.0003 0.0001 0.0072 0.0001 0.0005 0.0002 0.0008 0.0017 0 0.0004
Bud Neck 0.0077 0.0003 0.0037 0.0007 0.0004 0.0127 0.0118 0.0001 0.0004 0.0002 0.0003 0.0008 0.0008 0.0001 0.0004 0.001 0.0003 0.003
Bud Periphery 0.0021 0.0005 0.0007 0.0009 0 0.0001 0.0024 0.0009 0.0003 0 0.005 0 0.0006 0.0002 0.0009 0.0014 0 0.0007
Bud Site 0.0366 0.0042 0.0122 0.0011 0.0001 0.0001 0.0112 0.0058 0.0007 0.0001 0.0001 0.0002 0.0025 0.001 0.0066 0.004 0.0001 0.0003
Cell Periphery 0.0016 0.0003 0.0003 0.0001 0 0.0001 0.0006 0.0002 0.0001 0 0.0001 0.0002 0.0002 0.0001 0.0004 0.0001 0 0.0001
Cytoplasm 0.329 0.6754 0.6114 0.606 0.6019 0.7034 0.517 0.617 0.4925 0.5815 0.3873 0.7431 0.5406 0.7787 0.6311 0.6665 0.8716 0.726
Cytoplasmic Foci 0.0489 0.0196 0.0692 0.0477 0.1079 0.0933 0.0599 0.0155 0.0319 0.2013 0.0152 0.0433 0.0638 0.0279 0.05 0.0346 0.0125 0.0643
Eisosomes 0.0004 0.0001 0.0001 0 0 0 0.0002 0 0.0001 0 0.0002 0.0002 0.0005 0 0.0002 0.0001 0 0.0001
Endoplasmic Reticulum 0.0102 0.0049 0.0047 0.0032 0.0024 0.0073 0.0032 0.0024 0.002 0.0013 0.0043 0.0016 0.0079 0.003 0.0029 0.0028 0.002 0.003
Endosome 0.0642 0.0079 0.0326 0.0762 0.0087 0.0271 0.0074 0.0015 0.0093 0.0123 0.0035 0.0028 0.017 0.0041 0.0225 0.024 0.0048 0.0335
Golgi 0.0131 0.0029 0.0082 0.0139 0.0023 0.0024 0.0022 0.0004 0.0125 0.0012 0.0004 0.0004 0.0074 0.0006 0.0069 0.0177 0.0002 0.0041
Lipid Particles 0.0174 0.0005 0.0023 0.0071 0.0185 0.0034 0.0059 0.0001 0.0034 0.0006 0.0015 0.0018 0.0044 0.0003 0.0046 0.0217 0 0.0012
Mitochondria 0.0204 0.0077 0.002 0.0165 0.0018 0.0013 0.0028 0.0002 0.0027 0.0003 0.0017 0.0014 0.0068 0.0002 0.0084 0.0694 0.0001 0.0014
None 0.2773 0.2563 0.2238 0.2036 0.2257 0.1256 0.3335 0.347 0.4178 0.1801 0.5613 0.1836 0.2855 0.1752 0.2306 0.1048 0.1038 0.1373
Nuclear Periphery 0.0182 0.0016 0.0029 0.0019 0.0004 0.0111 0.0061 0.0005 0.0005 0.0006 0.0019 0.0005 0.002 0.0005 0.0009 0.0015 0.0006 0.0008
Nucleolus 0.0042 0.0001 0.0005 0.0003 0.0001 0.0001 0.0018 0.0001 0.0002 0 0.0003 0.0104 0.0001 0 0.0001 0.0002 0 0.0001
Nucleus 0.0234 0.0016 0.0033 0.0012 0.0008 0.0033 0.0088 0.0015 0.0012 0.001 0.003 0.0027 0.0016 0.0009 0.0014 0.0028 0.0018 0.0032
Peroxisomes 0.0322 0.0009 0.0033 0.0069 0.0266 0.0019 0.0137 0.0007 0.0022 0.0088 0.001 0.0016 0.0124 0.0009 0.0164 0.01 0.0001 0.0037
Punctate Nuclear 0.0241 0.0007 0.0033 0.0013 0.001 0.0021 0.0018 0.0004 0.0012 0.0067 0.0031 0.0036 0.0031 0.0045 0.0011 0.0009 0.0006 0.0019
Vacuole 0.0153 0.0019 0.002 0.006 0.0005 0.0019 0.0037 0.0005 0.0135 0.0003 0.0011 0.0006 0.0024 0.0006 0.0014 0.0054 0.0012 0.002
Vacuole Periphery 0.0044 0.0004 0.0007 0.0029 0.0001 0.0011 0.0009 0.0001 0.0008 0.0001 0.0003 0.0003 0.0006 0.0001 0.0004 0.003 0.0001 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.9452 20.8599 16.5846 17.4702 14.0468 15.5479 20.5893 21.6919 20.1691 19.5542
Translational Efficiency 0.6299 0.2998 0.3986 0.4029 0.361 0.5134 0.4179 0.3978 0.3956 0.4482

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2184 1282 146 1130 1859 904 136 465 4043 2186 282 1595

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 678.66 751.48 912.81 991.00 750.58 776.85 1100.16 967.63 711.73 761.97 1003.16 984.19
Standard Deviation 72.69 120.63 118.35 147.46 92.30 107.09 105.41 132.47 89.76 115.90 146.20 143.64
Intensity Change Log 2 — 0.147046 0.427626 0.546196 — 0.049630 0.551636 0.366450 — 0.096708 0.494077 0.454597

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001186 0.001156 0.005736 0.023389 0.001974 0.001185 0.001696 0.013725 0.001548 0.001168 0.003787 0.020571
Bud Neck 0.020347 0.010138 0.004984 0.013470 0.013424 0.023602 0.003019 0.009627 0.017163 0.015706 0.004036 0.012350
Bud Site 0.010889 0.015582 0.027234 0.084507 0.008584 0.023099 0.023713 0.062458 0.009829 0.018691 0.025536 0.078079
Cell Periphery 0.000175 0.000126 0.000445 0.000472 0.000097 0.000161 0.000440 0.000273 0.000139 0.000141 0.000443 0.000414
Cytoplasm 0.502203* 0.585955* 0.306102* 0.262845* 0.518137* 0.449615* 0.343254* 0.299745* 0.509529* 0.529573* 0.324019* 0.273602*
Cytoplasmic Foci 0.253566* 0.161441 0.047814 0.095723 0.241635* 0.256822* 0.055096 0.090272 0.248080* 0.200885* 0.051326 0.094134
Eisosomes 0.000334 0.000082 0.000161 0.000407 0.000141 0.000168 0.000170 0.000083 0.000245 0.000117 0.000166 0.000312
Endoplasmic Reticulum 0.000671 0.001159 0.014455 0.002741 0.001012 0.000921 0.009015 0.001582 0.000828 0.001060 0.011831 0.002403
Endosome 0.009205 0.012202 0.009724 0.018753 0.010500 0.037375 0.016729 0.023016 0.009800 0.022612 0.013103 0.019996
Golgi 0.003573 0.002233 0.000393 0.009337 0.002457 0.006096 0.000301 0.009119 0.003060 0.003831 0.000349 0.009273
Lipid Particles 0.007137 0.004514 0.006220 0.003773 0.004814 0.005568 0.007493 0.005372 0.006069 0.004950 0.006834 0.004239
Mitochondria 0.004398 0.001927 0.000495 0.008875 0.002101 0.006348 0.000871 0.001278 0.003341 0.003755 0.000676 0.006660
Mitotic Spindle 0.002388 0.009082 0.004543 0.237940* 0.003305 0.007519 0.006580 0.157695* 0.002810 0.008435 0.005525 0.214546*
None 0.006493 0.007023 0.003289 0.004386 0.002089 0.001418 0.003089 0.003552 0.004468 0.004705 0.003192 0.004143
Nuclear Periphery 0.000169 0.000907 0.001731 0.001399 0.000304 0.000291 0.001648 0.000892 0.000231 0.000652 0.001691 0.001251
Nuclear Periphery Foci 0.000639 0.005680 0.011541 0.006056 0.000689 0.000617 0.014884 0.004623 0.000662 0.003586 0.013153 0.005638
Nucleolus 0.001484 0.001786 0.000964 0.003240 0.000800 0.001305 0.000597 0.003609 0.001169 0.001587 0.000787 0.003348
Nucleus 0.114608 0.096440 0.358286* 0.061454 0.113236 0.060710 0.179720* 0.069842 0.113977 0.081664 0.272169* 0.063900
Peroxisomes 0.022249 0.013767 0.008090 0.031853 0.014222 0.017404 0.002151 0.038510 0.018558 0.015271 0.005226 0.033793
Vacuole 0.037646 0.067736 0.187409 0.121729 0.059803 0.097108 0.329176* 0.200234* 0.047834 0.079883 0.255779* 0.144616
Vacuole Periphery 0.000642 0.001063 0.000383 0.007653 0.000676 0.002666 0.000359 0.004494 0.000658 0.001726 0.000371 0.006732

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.08 -2.22 -3.79 -3.77 -1.65 1.13 0.25 -1.61 -2.04 -1.74 1.04 -1.90 -3.98 -4.28 -2.64
Bud Neck 6.79 10.16 6.08 -0.93 -4.83 -4.68 9.14 2.77 6.22 -3.84 1.31 13.50 6.16 4.11 -6.77
Bud Site -2.81 -2.05 -11.12 -9.37 -4.14 -5.53 -1.90 -6.78 -3.70 -3.53 -6.09 -2.78 -13.21 -9.49 -5.80
Cell Periphery 2.84 -6.46 -3.60 -4.88 3.41 -5.03 -7.31 -3.69 -1.46 3.55 -0.25 -9.63 -5.48 -4.96 4.51
Cytoplasm -7.56 11.47 23.48 27.07 -0.31 5.39 11.60 16.46 10.82 -0.45 -2.31 16.31 29.22 27.32 -0.42
Cytoplasmic Foci 12.83 27.28 28.29 14.12 -4.11 -1.28 25.72 20.56 19.00 -3.43 8.52 37.58 35.12 23.33 -5.37
Eisosomes 8.31 4.69 2.74 -1.21 0.34 -1.49 -1.63 5.25 5.51 5.74 7.09 3.69 2.50 -0.38 0.89
Endoplasmic Reticulum -4.07 -7.51 -9.71 -6.85 6.49 0.47 -9.63 -5.69 -5.30 8.33 -2.15 -10.54 -10.61 -8.47 9.01
Endosome -2.73 0.06 2.15 4.45 1.65 -10.20 -1.76 -1.93 6.95 -0.14 -9.78 -1.45 0.67 9.23 1.76
Golgi 3.64 11.89 1.61 -0.33 -2.96 -4.14 8.39 -0.36 1.76 -1.79 -1.70 14.54 0.69 1.57 -3.43
Lipid Particles 2.68 1.00 4.86 0.79 2.91 -1.01 -1.66 1.48 2.08 2.49 1.90 -0.17 4.87 1.82 3.93
Mitochondria 3.14 5.39 1.79 -0.69 -2.41 -3.19 4.22 4.55 4.36 -0.70 -0.48 6.62 1.98 2.13 -2.46
Mitotic Spindle -3.30 -1.71 -17.87 -16.89 -16.83 -2.20 -2.16 -8.82 -8.35 -4.40 -3.92 -2.49 -19.79 -18.80 -13.95
None -0.16 3.63 2.86 2.57 -1.11 2.04 0.17 -0.78 -2.16 -0.59 -0.02 2.75 1.38 1.21 -1.59
Nuclear Periphery -2.55 -11.92 -15.66 -3.59 1.30 0.72 -11.02 -8.56 -8.73 2.09 -2.38 -16.30 -17.42 -6.63 2.13
Nuclear Periphery Foci -3.59 -3.84 -8.17 -1.12 2.08 1.52 -6.22 -5.03 -5.17 2.12 -3.46 -6.24 -9.53 -3.85 3.01
Nucleolus -1.01 -0.34 -0.18 0.48 0.22 -0.33 1.11 -1.78 -1.69 -2.15 -1.10 0.15 -1.54 -0.97 -1.25
Nucleus 3.86 -9.73 -1.12 -3.89 9.32 11.94 -4.67 2.80 -4.31 5.56 9.86 -10.23 0.30 -6.43 10.06
Peroxisomes 3.82 6.05 4.08 0.71 -2.17 -1.24 8.71 -1.38 -0.50 -5.50 2.12 9.34 2.29 0.54 -5.10
Vacuole -11.17 -10.93 -25.73 -20.19 0.20 -7.59 -15.17 -19.32 -16.28 2.16 -12.68 -17.89 -31.23 -25.27 2.64
Vacuole Periphery -1.80 4.69 -2.50 -1.57 -3.17 -5.08 3.92 -1.09 1.59 -1.65 -5.10 6.01 -2.69 -0.01 -3.59
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in proteolytic activation of Rim101p; part of response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation
Localization
Cell Percentages cytoplasm (41%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Rim20

Rim20


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rim20-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available