Standard name
Human Ortholog
Description Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.7 0.77 0.9 0.97 0.95 0.93 0.87 0.9 0.84 0.88 0.81 0.85 0.98 0.98 0.98 0.64 0.6 0.63 0.12 0.11 0.17 0.18 0.15 0.19
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.07 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.08 0 0.09 0.16 0.15 0.24 0.2 0.28 0.25 0 0 0 0 0 0 0 0 0 0 0 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.41 0.33 0.1 0 0 0.05 0.07 0.06 0.05 0.09 0.07 0.1 0 0 0 0.46 0.49 0.48 0.77 0.8 0.73 0.73 0.7 0.67
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 2 0
Bud 0 0 3 4 0 5 0 7 3 4 0 3 0 1 1 0 0 0 2 5 1 2 2 0
Bud Neck 0 0 4 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 3 0 1 1
Bud Site 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 0 0 0 1 2 0 1 2 0 0 0 1 1 0 0 0 0 0 0 0 0 0
Cytoplasm 202 476 336 193 224 255 398 475 362 455 185 234 258 284 308 263 128 164 37 73 67 34 31 44
Endoplasmic Reticulum 2 3 1 0 0 1 0 0 0 1 3 0 0 1 0 19 7 5 2 3 2 3 4 6
Endosome 12 6 0 0 0 0 0 0 0 0 0 0 3 1 2 20 7 18 11 13 4 1 4 4
Golgi 2 1 0 0 1 0 0 0 0 0 0 0 0 0 0 1 3 0 2 2 0 0 3 1
Mitochondria 2 9 12 15 10 25 75 77 104 104 65 69 0 1 3 11 3 7 7 14 17 5 8 12
Nucleus 11 6 0 0 1 0 11 3 2 2 2 1 0 0 1 24 9 10 1 1 0 0 0 0
Nuclear Periphery 0 1 1 0 0 1 4 5 0 1 1 0 1 0 1 0 0 0 0 1 0 0 0 0
Nucleolus 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 2 1 3 0 0 0 1
Vac/Vac Membrane 119 200 36 2 8 15 30 32 22 49 15 28 3 2 2 187 104 125 249 520 286 144 148 161
Unique Cell Count 287 615 374 199 236 274 460 525 431 518 229 276 264 289 315 409 212 261 323 653 391 198 212 239
Labelled Cell Count 350 703 394 214 244 304 520 599 496 619 271 335 265 291 319 526 262 331 323 653 391 198 212 239


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.5 4.1 3.4 3.4 3.7 3.4 3.3 3.4 2.9 3.0 3.0 3.0 4.9 4.5 3.9 6.7 7.4 6.9 4.9 5.6 5.4
Std Deviation (1e-4) 0.7 0.7 0.6 1.1 0.9 0.7 0.8 1.0 0.4 0.8 0.4 0.9 5.0 1.2 1.1 1.9 2.0 2.0 1.8 2.2 1.5
Intensity Change (Log2) – – – 0.0 0.12 0.01 -0.04 -0.01 -0.22 -0.17 -0.2 -0.21 0.53 0.41 0.2 0.99 1.12 1.02 0.53 0.71 0.66

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 11.2 10.8 10.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.1197 1.1288 0.5763 0.046 0.0136 0.6431 4.5601 3.929 4.2928 3.5922 4.0212 4.4909 3.8856 3.6577 4.041 3.5363 3.616 3.6369
Actin 0.0001 0.0002 0.0003 0.0001 0.0001 0.0002 0.0334 0.0002 0.0117 0.0005 0.0009 0.0042 0.0221 0.0054 0.0118 0.0039 0.0211 0.005
Bud 0 0.0001 0.0002 0.0002 0.0001 0.0001 0.0022 0.0043 0.0052 0.0006 0.0005 0.002 0.0029 0.0029 0.0021 0.0065 0.02 0.0062
Bud Neck 0.0001 0.0002 0.0002 0.0005 0.0005 0.0006 0.0092 0.0069 0.015 0.003 0.0044 0.0055 0.0014 0.0053 0.0013 0.0005 0.0008 0.0016
Bud Periphery 0 0.0001 0.0003 0.0002 0.0001 0.0002 0.0035 0.0068 0.0084 0.0012 0.0009 0.004 0.0022 0.0015 0.0028 0.0057 0.0057 0.0047
Bud Site 0.0002 0.0006 0.0005 0.0006 0.0002 0.0002 0.0173 0.0119 0.0181 0.0057 0.0024 0.0011 0.027 0.0148 0.0076 0.0015 0.0017 0.0013
Cell Periphery 0.0002 0.0004 0.0004 0.0003 0.0001 0.0002 0.0011 0.0008 0.0007 0.0005 0.0016 0.0005 0.0009 0.0012 0.0005 0.0004 0.0003 0.0003
Cytoplasm 0.1736 0.3534 0.3336 0.4366 0.3365 0.5117 0.1067 0.2501 0.1794 0.1619 0.1734 0.269 0.1134 0.2429 0.1599 0.0924 0.2681 0.2939
Cytoplasmic Foci 0.0109 0.0156 0.018 0.0317 0.0426 0.0142 0.0427 0.0279 0.0483 0.0582 0.0572 0.0504 0.0545 0.0438 0.0362 0.1073 0.0221 0.0509
Eisosomes 0.0003 0.0001 0.0001 0 0.0001 0.0001 0.0005 0.0001 0.0002 0.0001 0.0001 0.0001 0.0009 0.0002 0.0005 0.0002 0.0002 0.0003
Endoplasmic Reticulum 0.0035 0.004 0.0042 0.0033 0.0022 0.004 0.0052 0.0044 0.0043 0.0047 0.0017 0.005 0.0072 0.0046 0.003 0.0031 0.0017 0.0036
Endosome 0.0183 0.0199 0.0247 0.0608 0.0904 0.0164 0.0457 0.0541 0.0596 0.1033 0.1125 0.058 0.0601 0.0411 0.0268 0.2077 0.0615 0.0599
Golgi 0.0003 0.0003 0.0005 0.0014 0.001 0.0003 0.0086 0.0009 0.0081 0.004 0.0173 0.0034 0.0061 0.0021 0.0022 0.0035 0.0039 0.0016
Lipid Particles 0.0014 0.0009 0.0012 0.0007 0.0027 0.0009 0.0168 0.0016 0.0132 0.0267 0.0107 0.0028 0.0245 0.0058 0.0048 0.0049 0.0014 0.0043
Mitochondria 0.0002 0.0004 0.0006 0.0011 0.0008 0.0005 0.0084 0.0015 0.0126 0.0032 0.0171 0.0087 0.0024 0.0015 0.0046 0.0083 0.016 0.002
None 0.7701 0.5604 0.595 0.3876 0.4925 0.4121 0.575 0.527 0.5379 0.408 0.4574 0.477 0.6177 0.5474 0.6929 0.3759 0.5127 0.5084
Nuclear Periphery 0.001 0.0018 0.0013 0.001 0.0007 0.0016 0.0227 0.0025 0.0068 0.0052 0.0016 0.0029 0.015 0.0021 0.0027 0.0125 0.001 0.0023
Nucleolus 0.0002 0.0004 0.0003 0.0004 0.0003 0.0004 0.0022 0.0025 0.0023 0.0046 0.0019 0.0017 0.0017 0.0053 0.0013 0.003 0.0005 0.0008
Nucleus 0.001 0.003 0.0029 0.0019 0.0017 0.0046 0.0217 0.008 0.005 0.006 0.0063 0.0065 0.0025 0.009 0.0028 0.0058 0.0058 0.0027
Peroxisomes 0.0001 0.0002 0.0003 0.0003 0.0003 0.0002 0.0307 0.0004 0.0089 0.0295 0.0264 0.0083 0.009 0.0021 0.0041 0.0035 0.0067 0.001
Punctate Nuclear 0.0006 0.001 0.001 0.0005 0.0005 0.0021 0.0079 0.0024 0.0055 0.0052 0.0014 0.0032 0.0053 0.011 0.0054 0.0068 0.001 0.0026
Vacuole 0.0169 0.035 0.0131 0.0678 0.024 0.0281 0.0343 0.0818 0.0447 0.1574 0.0987 0.0812 0.0204 0.0479 0.0241 0.1339 0.0447 0.0415
Vacuole Periphery 0.0009 0.002 0.001 0.0029 0.0024 0.0013 0.0044 0.004 0.0041 0.0105 0.0056 0.0046 0.0027 0.0023 0.0025 0.0129 0.0033 0.0049

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17.2323 11.5535 16.0747 17.8281 12.3931 7.2658 16.0015 19.2181 17.1482 19.4683
Translational Efficiency 0.5929 0.6763 0.6363 0.5016 0.5368 1.241 0.6118 0.3604 0.4536 0.4663

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
225 1919 156 935 1315 1683 1391 434 1540 3602 1547 1369

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 628.80 726.52 975.14 775.41 618.68 707.69 814.66 811.29 620.16 717.72 830.84 786.78
Standard Deviation 155.71 103.44 116.52 113.44 88.99 100.10 104.32 106.86 101.57 102.32 116.14 112.64
Intensity Change Log 2 — 0.208401 0.633008 0.302358 — 0.193924 0.397005 0.391024 — 0.201240 0.520782 0.347013

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000233 0.000422 0.000538 0.000975 0.000109 0.000360 0.000163 0.000432 0.000127 0.000393 0.000201 0.000803
Bud Neck 0.020824 0.030871 0.002116 0.007977 0.017727 0.046380 0.004200 0.005682 0.018180 0.038118 0.003990 0.007249
Bud Site 0.017729 0.017658 0.007560 0.029245 0.005790 0.025599 0.006621 0.027485 0.007535 0.021368 0.006715 0.028687
Cell Periphery 0.001862 0.000076 0.000418 0.000310 0.000106 0.000564 0.000246 0.000173 0.000362 0.000304 0.000263 0.000267
Cytoplasm 0.422837 0.431792 0.351673 0.485528 0.497697 0.228920 0.403810 0.460318 0.486760 0.337002 0.398552 0.477536
Cytoplasmic Foci 0.182676 0.113434 0.061663 0.037716 0.137152 0.132552 0.020188 0.053650 0.143803 0.122367 0.024371 0.042767
Eisosomes 0.000282 0.000054 0.000155 0.000084 0.000087 0.000255 0.000067 0.000077 0.000116 0.000148 0.000076 0.000082
Endoplasmic Reticulum 0.000953 0.000944 0.007292 0.001674 0.000885 0.002837 0.002839 0.002048 0.000895 0.001829 0.003288 0.001792
Endosome 0.025653 0.029534 0.017126 0.008595 0.026789 0.076845 0.003624 0.009467 0.026623 0.051640 0.004986 0.008871
Golgi 0.001920 0.001570 0.000350 0.003218 0.001040 0.005224 0.000550 0.011316 0.001169 0.003277 0.000530 0.005785
Lipid Particles 0.014907 0.003039 0.006388 0.001884 0.005580 0.009201 0.002012 0.002430 0.006943 0.005918 0.002454 0.002057
Mitochondria 0.001989 0.003034 0.001773 0.003317 0.002324 0.010639 0.000499 0.001716 0.002275 0.006587 0.000628 0.002810
Mitotic Spindle 0.000641 0.006247 0.004454 0.022867 0.001635 0.008308 0.003159 0.024415 0.001490 0.007210 0.003290 0.023358
None 0.020450 0.000878 0.001332 0.005611 0.004843 0.004118 0.006569 0.004866 0.007123 0.002392 0.006041 0.005375
Nuclear Periphery 0.000965 0.000599 0.001826 0.001152 0.000772 0.001057 0.001932 0.002084 0.000800 0.000813 0.001921 0.001448
Nuclear Periphery Foci 0.000792 0.000301 0.017261 0.001556 0.000387 0.000264 0.001596 0.002423 0.000447 0.000284 0.003176 0.001831
Nucleolus 0.001965 0.001187 0.000595 0.000631 0.001671 0.002884 0.000810 0.000676 0.001714 0.001980 0.000788 0.000645
Nucleus 0.137266 0.078583 0.231808 0.171952 0.095549 0.087948 0.447761 0.158611 0.101644 0.082959 0.425985 0.167722
Peroxisomes 0.003880 0.006836 0.000768 0.003739 0.003793 0.012614 0.000328 0.001489 0.003806 0.009536 0.000372 0.003025
Vacuole 0.140784 0.270559 0.283174 0.206718 0.194269 0.335126 0.092833 0.228247 0.186455 0.300727 0.112027 0.213543
Vacuole Periphery 0.001390 0.002380 0.001730 0.005253 0.001792 0.008305 0.000192 0.002395 0.001734 0.005148 0.000347 0.004347

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.83 -4.37 -1.27 -0.62 -0.05 -3.25 -4.40 -3.15 0.40 -1.54 -2.50 -5.29 -2.04 -0.62 -1.38
Bud Neck -1.88 3.78 2.92 13.06 -4.34 -10.90 9.00 7.63 16.70 -1.24 -10.29 9.54 8.08 20.74 -1.87
Bud Site 0.25 1.75 -0.02 -0.59 -3.73 -9.43 -0.37 -2.82 2.53 -2.60 -8.20 0.81 -4.28 1.46 -4.88
Cell Periphery 3.67 2.98 3.40 -2.97 3.88 -4.62 -5.97 -2.06 4.35 4.55 0.84 1.68 2.35 2.15 1.81
Cytoplasm -0.29 4.48 1.28 2.57 -4.18 27.05 13.00 7.77 -9.54 -1.03 17.12 13.48 8.78 -5.84 -3.72
Cytoplasmic Foci 5.59 9.65 12.41 23.56 4.60 0.93 26.33 18.39 18.72 -5.09 4.80 28.17 25.67 31.10 -4.18
Eisosomes 4.66 2.24 4.11 -6.53 7.04 -3.46 2.15 1.09 3.59 -0.84 -1.34 3.46 4.09 2.94 1.16
Endoplasmic Reticulum -0.06 -8.98 -7.48 -10.28 6.88 -5.52 -14.74 -7.80 -0.10 4.32 -5.05 -16.93 -11.91 -4.32 7.94
Endosome -0.80 2.51 5.57 14.49 5.94 -15.67 14.64 12.20 24.45 -2.35 -11.65 14.93 13.77 27.44 -1.47
Golgi 0.41 1.48 0.38 0.02 -1.84 -7.31 2.03 -1.28 0.56 -1.57 -5.51 2.42 -1.24 1.11 -2.17
Lipid Particles 3.24 2.27 3.52 4.27 6.54 -4.69 7.18 6.54 10.00 -1.19 1.24 6.36 7.15 10.96 3.16
Mitochondria -1.69 0.94 0.32 1.70 -0.59 -8.83 4.51 2.96 10.91 -1.95 -7.84 4.74 1.33 8.11 -2.01
Mitotic Spindle -4.00 -1.06 -6.00 -3.88 -4.46 -4.36 -1.40 -3.67 -2.10 -3.32 -4.85 -1.65 -6.59 -4.25 -5.89
None 3.80 3.72 3.16 -5.84 -4.92 0.44 -0.39 0.23 -0.27 0.69 3.89 1.66 2.37 -2.90 0.67
Nuclear Periphery 0.73 -2.12 -2.48 -11.07 -0.46 -1.05 -8.56 -7.55 -6.32 -2.09 -0.24 -8.88 -7.66 -10.15 0.84
Nuclear Periphery Foci 1.65 -9.53 -4.09 -9.91 8.84 3.53 -8.47 -6.51 -6.93 -1.43 2.74 -11.35 -11.02 -12.26 4.17
Nucleolus 1.19 2.20 2.25 6.60 0.42 -2.62 3.86 4.05 6.31 0.65 -0.69 4.37 5.04 8.28 1.86
Nucleus 5.30 -4.13 -3.70 -15.13 2.01 1.51 -41.99 -9.81 -10.39 19.95 4.45 -40.21 -13.83 -18.05 25.69
Peroxisomes -3.17 4.03 1.93 5.50 -1.45 -6.97 6.75 5.45 10.17 -1.58 -7.39 7.56 3.57 10.21 -2.11
Vacuole -10.14 -8.19 -11.12 -3.38 1.06 -14.82 6.77 -8.57 0.63 -12.41 -16.50 3.28 -13.53 -1.60 -16.15
Vacuole Periphery -2.99 0.28 -1.13 -0.21 -1.03 -11.66 7.96 1.69 10.70 -1.70 -10.49 7.43 -0.35 4.74 -2.71
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects
Localization
Cell Percentages vacuole (65%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Kre5

Kre5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Kre5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available