ORF
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; relocalizes from nucleus to cytoplasm upon DNA replication stress; YOR342C has a paralog, YAL037W, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.12 0.25 0.33 0.4 0.95 0.85 0.81 0.83 0.73 0.72 0.64 0.68 0.69 0.94 0.98 0.53 0.48 0.46 0.13 0.11 0.24 0.86 0.86 0.82
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0.1 0.1 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.23 0 0 0.09 0 0.2 0.33 0.22 0.44 0.35 0.49 0.39 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.37 0.4 0.52 0.36 0 0 0 0 0 0 0 0 0.15 0 0 0.09 0.11 0.07 0.66 0.63 0.5 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.5 0.6 0.25 0.26 0.05 0.06 0 0 0 0 0 0 0.27 0.08 0 0.47 0.42 0.47 0.11 0.12 0.14 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 2 4 10
Bud 0 0 0 0 0 3 5 2 10 7 3 3 0 0 0 0 0 0 5 8 4 2 10 14
Bud Neck 0 0 2 1 2 2 5 8 3 8 3 12 0 0 1 0 0 0 0 1 1 1 1 3
Bud Site 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 3 1 0 1 0 1 0 0 0 1 0 0 0 1 0 0 0 0 1 2
Cytoplasm 14 50 72 81 334 263 333 373 188 258 153 191 164 412 457 79 78 66 17 24 59 243 343 342
Endoplasmic Reticulum 0 2 0 0 1 1 0 0 0 1 0 1 1 1 1 4 10 8 0 0 1 0 3 1
Endosome 0 1 1 2 2 2 1 1 0 0 0 0 7 1 2 16 16 14 1 4 3 5 4 5
Golgi 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 1 0 1 0 0 1 0 1
Mitochondria 26 5 0 18 8 61 137 101 114 124 117 109 0 0 1 0 1 2 0 4 3 5 9 12
Nucleus 42 80 112 73 2 5 3 9 4 9 4 2 37 5 1 13 18 10 86 140 125 3 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Nucleolus 0 0 0 0 1 0 1 1 2 0 0 1 0 1 0 1 1 1 0 1 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 1 3 3 2 2 9 1 0 0 4 5 3 2 6 10 3 8 10
Vac/Vac Membrane 57 121 53 53 17 20 6 10 1 12 3 8 64 35 15 70 68 68 14 27 36 6 3 4
Unique Cell Count 114 201 215 201 352 308 413 449 257 356 239 280 239 437 465 149 163 144 131 224 251 284 399 417
Labelled Cell Count 139 259 241 228 371 358 493 509 325 422 285 337 275 457 478 187 198 173 131 224 251 284 399 417


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.8 7.2 6.3 5.4 4.9 3.9 3.4 4.1 3.3 3.4 3.2 3.4 6.1 5.8 5.6 8.2 7.9 7.5 5.4 5.3 5.7
Std Deviation (1e-4) 0.9 1.2 1.1 1.3 1.3 1.3 1.0 1.3 1.5 1.2 1.6 1.1 1.1 1.0 1.2 1.7 2.0 1.8 1.6 1.3 1.5
Intensity Change (Log2) – – – -0.2 -0.36 -0.68 -0.86 -0.62 -0.9 -0.87 -0.96 -0.88 -0.03 -0.11 -0.16 0.4 0.34 0.26 -0.22 -0.24 -0.14


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.4 15.7 12.2 11.7 12.7 8.6 9.1 6.5 7.7 7.5 16.7 18.9 3.7 2.8 2.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 4.6 4.3 4.3
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 4.5 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus -3.2 -14.9 -13.6 -15.8 -15.6 -12.7 -14.0 -12.3 -13.5 -8.3 -15.9 -16.9 -8.6 -8.3 -8.9
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0.4 -7.0 -5.9 -9.5 -9.2 -8.2 -7.8 -7.6 -7.3 0.5 -5.8 -8.7 4.4 3.5 4.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.6414 1.3852 1.1765 0.8555 0.4969 1.1266 1.9181 2.3013 1.8654 1.0068 0.7128 1.6782 2.094 2.4998 2.2905 1.7598 1.415 2.0435
Actin 0.0402 0.0003 0.0153 0.0016 0.0191 0.0032 0.0127 0.0001 0.0146 0.0002 0.0004 0.0021 0.0001 0.0001 0.0003 0.0003 0.0004 0.0002
Bud 0.0012 0.0024 0.0006 0.0004 0.0008 0.0013 0.0033 0.0003 0.0008 0.0002 0.0002 0.0047 0.0005 0.0001 0.0012 0.0008 0.0007 0.001
Bud Neck 0.0033 0.0006 0.0016 0.001 0.0044 0.0049 0.0071 0.0005 0.0007 0.0011 0.0021 0.0026 0.0004 0.0004 0.0004 0.0008 0.0015 0.0023
Bud Periphery 0.0015 0.0006 0.0005 0.0003 0.0011 0.0015 0.0007 0.0001 0.0019 0.0002 0.0001 0.0008 0.0005 0 0.0002 0.0002 0.0003 0.0003
Bud Site 0.0026 0.0025 0.0017 0.001 0.0016 0.0004 0.0043 0.0018 0.0013 0.0002 0.0003 0.0002 0.0005 0.0004 0.0008 0.0003 0.0009 0.0003
Cell Periphery 0.0002 0 0.0001 0 0.0001 0.0001 0.0001 0 0.0001 0 0 0 0 0 0.0001 0 0 0
Cytoplasm 0.138 0.2711 0.1307 0.1984 0.2598 0.1458 0.113 0.2188 0.1064 0.1484 0.1622 0.1086 0.1152 0.1891 0.1312 0.2003 0.2324 0.1282
Cytoplasmic Foci 0.0246 0.0023 0.0071 0.016 0.0142 0.007 0.0114 0.0018 0.0076 0.0006 0.0017 0.003 0.0043 0.0011 0.003 0.0027 0.0047 0.0063
Eisosomes 0.0002 0 0.0002 0 0.0002 0.0001 0.0002 0 0.0001 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0058 0.0027 0.0027 0.0062 0.0084 0.0025 0.0065 0.0034 0.0018 0.0014 0.0162 0.0014 0.0022 0.0031 0.0023 0.0034 0.0026 0.0014
Endosome 0.0421 0.003 0.0207 0.0421 0.0339 0.011 0.0263 0.0023 0.0074 0.0012 0.0081 0.0041 0.003 0.0026 0.0038 0.0078 0.0069 0.0032
Golgi 0.0131 0.0001 0.0088 0.0027 0.0057 0.0027 0.0031 0 0.0022 0 0.0001 0.0006 0.0001 0 0.0001 0.0001 0.0002 0.0001
Lipid Particles 0.0208 0.0001 0.0065 0.0084 0.005 0.0064 0.0043 0.0001 0.0039 0 0.0002 0.0017 0.0002 0.0001 0.0003 0.0001 0.0001 0.0002
Mitochondria 0.0102 0.0005 0.011 0.0029 0.0033 0.0037 0.0017 0.0004 0.0144 0.0004 0.0019 0.001 0.0015 0.0003 0.0018 0.0004 0.0007 0.0003
None 0.0496 0.045 0.0551 0.1094 0.1439 0.0562 0.0266 0.0613 0.06 0.0022 0.0134 0.0196 0.0352 0.0143 0.0214 0.0073 0.0683 0.0144
Nuclear Periphery 0.0432 0.0223 0.0184 0.0383 0.0418 0.0181 0.027 0.0146 0.0136 0.0159 0.0338 0.0121 0.0135 0.0214 0.0126 0.0185 0.0185 0.0099
Nucleolus 0.0027 0.0018 0.0024 0.0019 0.0074 0.0029 0.0048 0.0015 0.0017 0.0015 0.0057 0.0023 0.002 0.0012 0.0033 0.0022 0.0023 0.0023
Nucleus 0.5424 0.6246 0.6721 0.5434 0.376 0.6864 0.7103 0.68 0.7109 0.8166 0.7267 0.8088 0.8051 0.7539 0.7995 0.7192 0.6288 0.7915
Peroxisomes 0.0161 0.0001 0.0091 0.0027 0.0016 0.0012 0.0025 0.0001 0.0065 0 0.0001 0.0014 0.0003 0 0.0001 0.0001 0.0002 0.0001
Punctate Nuclear 0.0261 0.0173 0.0317 0.017 0.0652 0.0419 0.0302 0.0108 0.0406 0.0081 0.0237 0.024 0.0128 0.0097 0.0161 0.0337 0.0265 0.0367
Vacuole 0.0112 0.0023 0.0025 0.0046 0.0045 0.0018 0.0029 0.0017 0.0024 0.0015 0.0021 0.001 0.0021 0.0016 0.0012 0.0015 0.0035 0.0011
Vacuole Periphery 0.0049 0.0005 0.001 0.0016 0.0021 0.001 0.001 0.0003 0.0011 0.0003 0.001 0.0004 0.0004 0.0004 0.0003 0.0004 0.0006 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 39.6536 13.3572 33.547 51.0112 34.2751 17.2311 8.0513 10.5176 19.2154 49.0076
Translational Efficiency 0.5057 0.6795 0.4746 0.4425 0.7204 1.0447 0.582 0.2718 0.6713 0.5781

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
274 527 942 1730 1267 1491 1728 1253 1541 2018 2670 2983

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 820.36 902.65 1088.20 1147.46 733.44 855.84 1167.69 1124.96 748.89 868.06 1139.65 1138.01
Standard Deviation 100.58 121.43 153.06 212.74 99.95 117.57 162.87 190.82 105.44 120.36 163.94 204.13
Intensity Change Log 2 — 0.137910 0.407615 0.484115 — 0.222662 0.670906 0.617123 — 0.178536 0.537896 0.548429

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000134 0.001080 0.000611 0.000780 0.000154 0.000421 0.000695 0.001119 0.000150 0.000593 0.000665 0.000922
Bud Neck 0.001554 0.003614 0.004149 0.010794 0.001566 0.006064 0.004644 0.009606 0.001564 0.005424 0.004469 0.010295
Bud Site 0.000868 0.002966 0.002901 0.005256 0.000970 0.006154 0.001321 0.010130 0.000952 0.005321 0.001879 0.007303
Cell Periphery 0.000142 0.000127 0.000109 0.000158 0.000127 0.000143 0.000094 0.000138 0.000129 0.000139 0.000100 0.000150
Cytoplasm 0.168973* 0.170518* 0.052639 0.063559 0.267200* 0.166961* 0.032105 0.081334 0.249735* 0.167890* 0.039350 0.071025
Cytoplasmic Foci 0.045958 0.017856 0.000413 0.001471 0.026656 0.013272 0.001145 0.005867 0.030088 0.014469 0.000887 0.003318
Eisosomes 0.000054 0.000030 0.000018 0.000016 0.000032 0.000022 0.000015 0.000017 0.000036 0.000024 0.000016 0.000016
Endoplasmic Reticulum 0.003472 0.004021 0.005384 0.004125 0.001851 0.002550 0.005176 0.003143 0.002139 0.002934 0.005249 0.003713
Endosome 0.002188 0.002852 0.000477 0.001447 0.001536 0.002595 0.000427 0.002125 0.001652 0.002662 0.000445 0.001732
Golgi 0.000393 0.000888 0.000062 0.001024 0.000691 0.000984 0.000636 0.002872 0.000638 0.000959 0.000434 0.001800
Lipid Particles 0.003281 0.002215 0.000284 0.000337 0.002137 0.001367 0.000192 0.000497 0.002340 0.001588 0.000224 0.000404
Mitochondria 0.005957 0.004216 0.000890 0.003345 0.002226 0.003415 0.001161 0.002740 0.002889 0.003624 0.001066 0.003091
Mitotic Spindle 0.004084 0.006696 0.001039 0.021559 0.001333 0.009910 0.003479 0.058938 0.001822 0.009071 0.002618 0.037260
None 0.005027 0.007378 0.003501 0.006651 0.009604 0.008011 0.003655 0.008692 0.008790 0.007846 0.003600 0.007508
Nuclear Periphery 0.001011 0.001105 0.001054 0.001490 0.000687 0.001330 0.000962 0.000856 0.000745 0.001271 0.000995 0.001224
Nuclear Periphery Foci 0.000959 0.001171 0.000414 0.002074 0.000841 0.000672 0.000389 0.001187 0.000862 0.000802 0.000397 0.001702
Nucleolus 0.001418 0.002332 0.000326 0.000988 0.002207 0.002902 0.000314 0.001553 0.002066 0.002753 0.000318 0.001225
Nucleus 0.740752* 0.754960* 0.916585* 0.865568* 0.669674* 0.760369* 0.936891* 0.795996* 0.682312* 0.758957* 0.929727* 0.836344*
Peroxisomes 0.000887 0.001911 0.000081 0.000141 0.001401 0.000824 0.000434 0.001905 0.001310 0.001108 0.000310 0.000882
Vacuole 0.012322 0.012756 0.008978 0.008668 0.008536 0.011513 0.006192 0.010948 0.009210 0.011838 0.007175 0.009626
Vacuole Periphery 0.000566 0.001307 0.000084 0.000549 0.000570 0.000521 0.000073 0.000336 0.000570 0.000727 0.000077 0.000460

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.31 -6.40 -12.31 -0.35 -3.08 -1.87 -6.73 -11.27 -5.99 -4.63 -2.08 -9.00 -16.57 -3.67 -5.47
Bud Neck -3.11 -7.38 -16.68 -15.53 -15.04 -5.52 -8.29 -16.21 -12.79 -13.80 -6.17 -11.14 -23.19 -18.79 -20.06
Bud Site -1.77 -2.11 -11.41 -7.73 -7.65 -4.10 -2.86 -12.69 -7.51 -12.22 -4.43 -3.12 -17.00 -9.12 -14.90
Cell Periphery 1.04 1.35 -3.47 -4.69 -6.78 -0.98 3.67 -7.36 -4.17 -11.36 -0.55 3.17 -8.70 -5.80 -13.05
Cytoplasm -0.10 9.08 8.65 11.88 -1.74 10.32 30.76 23.65 14.18 -9.09 9.67 31.08 26.93 19.67 -8.98
Cytoplasmic Foci 3.93 6.60 6.27 5.98 -4.63 5.46 13.45 9.59 4.53 -5.17 6.57 14.61 12.56 8.17 -6.48
Eisosomes 3.81 5.23 4.64 0.79 -2.10 4.10 6.73 -2.59 -7.27 -10.93 5.12 7.88 1.88 -4.75 -9.56
Endoplasmic Reticulum -0.41 -1.93 -0.84 -1.31 3.83 -2.92 -9.82 -11.95 -7.48 2.51 -2.32 -9.61 -7.69 -7.03 4.07
Endosome -0.60 4.12 1.98 2.38 -3.27 -2.53 6.46 -2.62 0.69 -7.79 -2.74 7.44 -0.47 2.39 -7.47
Golgi -1.23 1.64 -1.06 0.43 -2.81 -0.58 0.64 -1.08 -0.60 -1.52 -0.80 1.08 -0.94 -0.08 -2.09
Lipid Particles 1.31 4.45 3.71 2.34 -4.74 1.67 4.82 2.63 1.16 -9.86 1.84 5.99 3.97 2.64 -10.06
Mitochondria 0.42 1.26 0.72 0.63 -4.92 -1.13 1.50 -0.38 1.07 -3.99 -0.63 1.98 0.05 1.03 -5.94
Mitotic Spindle -0.53 0.60 -8.56 -9.22 -11.92 -4.14 -1.22 -15.12 -13.30 -14.87 -4.02 -0.54 -18.72 -15.67 -18.76
None -1.42 2.14 -4.35 -1.63 -9.14 1.01 5.49 -1.21 -2.39 -10.67 0.78 5.80 -1.41 -2.41 -13.72
Nuclear Periphery -0.24 -1.18 -6.20 -9.55 -9.28 -3.58 -7.42 -14.21 -5.99 -10.21 -3.65 -7.17 -17.45 -9.08 -13.82
Nuclear Periphery Foci -0.08 1.46 -6.97 -7.05 -7.63 1.06 1.47 -8.10 -8.22 -8.28 0.61 2.11 -10.58 -10.63 -10.90
Nucleolus -1.65 5.18 -10.28 -8.20 -11.32 -1.20 3.42 -9.38 -8.62 -10.40 -1.53 4.30 -13.21 -11.74 -15.16
Nucleus -0.84 -9.06 -1.44 -0.71 16.51 -7.59 -28.99 0.23 7.11 25.22 -7.35 -29.52 -4.16 3.77 30.53
Peroxisomes -1.32 4.42 2.33 2.00 -5.22 0.77 1.77 -0.14 -1.88 -3.86 0.23 2.16 0.83 1.20 -4.36
Vacuole 0.07 -1.28 -4.32 -5.01 -3.06 -2.42 -1.70 -9.97 -8.14 -8.87 -2.38 -2.95 -12.08 -9.49 -9.29
Vacuole Periphery -0.84 1.26 0.62 1.24 -1.91 0.19 2.33 1.42 2.74 -4.31 -0.53 2.60 1.36 1.94 -3.04
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; relocalizes from nucleus to cytoplasm upon DNA replication stress; YOR342C has a paralog, YAL037W, that arose from the whole genome duplication
Localization
Cell Percentages nucleus (25%), cytoplasm (13%), mixed (56%)
Cell Cycle Regulation No
Subcompartmental Group N/A

YOR342C

YOR342C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yor342c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available