Standard name
Human Ortholog
Description Putative ortholog of human ETF-dH; found in a large supramolecular complex with other mitochondrial dehydrogenases; may have a role in oxidative stress response; ETF-dH is also known as electron transfer flavoprotein dehydrogenase
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0.06 0 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.06 – – – – – –
Cell Periphery 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.06 0.07 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0.07 0.06 0 0.12 0.06 0.09 0.1 0 0 0 0 0 0.08 0.08 0.09 0.13 0.1 0 0.08 0.08 0.06 0 0
Golgi 0 0 0.28 0.16 0.2 0 0.05 0 0 0 0 0 0.16 0.21 0.26 0.09 0.13 0.07 0 0.06 0.06 0.07 0.1 0.14
Mitochondria 0.92 0.75 0.54 0.85 0.58 0.76 0.71 0.74 0.87 0.87 0.93 0.88 0.9 0.64 0.48 0.15 0.11 0.14 0.83 0.69 0.65 0.72 0.68 0.63
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0.06 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0.08 0.06 0.06 0.07 0.09 0.05 0.07 0 0 0 0.06 0 0 0 0 0 0 0 0
Nucleolus 0.06 0 0 0 0 0 0.09 0.05 0.06 0.05 0.07 0 0 0 0 0.11 0.13 0.1 0 0 0 0 0 0
Peroxisomes 0.07 0.12 0.14 0.09 0.11 0.05 0.07 0.06 0 0 0 0 0.05 0.21 0.24 0.13 0.19 0.15 0.07 0.05 0.11 0 0 0
SpindlePole 0 0 0.1 0 0 0 0 0.05 0 0 0 0 0 0.08 0.14 0.23 0.12 0.16 0 0 0 0 0 0
Vac/Vac Membrane 0.09 0.18 0.2 0.11 0.22 0.15 0.12 0.11 0.06 0.08 0 0.06 0.12 0.05 0.06 0.13 0.14 0.18 0 0 0 0.05 0.08 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 3 1 4 1 1 1 1 0 0 0 1 1 5 2 1 3 0 3 10 4 2 3 5
Bud 11 6 2 5 4 3 7 15 3 3 6 8 0 10 10 3 4 5 0 5 0 0 2 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Bud Site 0 3 0 1 0 1 0 3 2 2 1 0 0 0 0 3 2 6 – – – – – –
Cell Periphery 5 10 6 9 5 9 5 2 4 4 2 2 0 3 5 5 7 7 0 0 0 0 0 0
Cytoplasm 2 4 1 2 5 4 7 7 4 2 5 7 0 1 5 2 5 9 0 0 0 0 4 0
Endoplasmic Reticulum 3 1 0 0 0 3 0 1 1 1 0 2 0 0 0 1 3 4 0 0 0 0 0 1
Endosome 10 22 7 8 31 16 30 51 9 9 1 8 2 13 16 5 14 10 4 29 11 7 7 6
Golgi 2 10 34 36 51 12 16 14 2 4 0 9 9 32 52 5 14 7 13 23 9 7 19 29
Mitochondria 303 254 66 188 146 206 241 392 187 222 202 272 52 99 97 8 12 14 278 254 97 81 135 133
Nucleus 3 2 0 0 0 0 10 5 1 3 2 1 0 2 0 3 5 6 0 0 0 0 0 0
Nuclear Periphery 11 8 3 3 5 23 22 33 15 24 11 21 1 1 2 3 3 4 2 0 0 0 1 0
Nucleolus 19 9 4 6 5 12 29 26 13 12 15 13 0 4 1 6 14 10 0 1 0 0 0 0
Peroxisomes 24 42 17 21 27 14 24 32 5 4 0 6 3 33 48 7 21 15 23 16 15 3 5 7
SpindlePole 5 8 12 4 9 7 13 28 4 4 2 10 0 12 27 12 13 16 2 6 4 1 0 0
Vac/Vac Membrane 30 62 25 24 55 42 40 56 13 20 8 19 7 7 12 7 15 19 2 11 3 5 16 16
Unique Cell Count 328 338 123 222 251 272 341 528 214 254 218 308 58 154 200 53 109 103 337 366 150 113 199 210
Labelled Cell Count 429 444 178 311 344 353 445 666 263 314 255 379 75 222 277 71 135 132 337 366 150 113 199 210


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.9 9.0 9.4 9.1 10.1 8.3 8.5 8.1 7.2 7.4 6.6 7.3 9.4 9.8 9.5 10.2 11.3 10.8 8.6 10.0 10.8
Std Deviation (1e-4) 1.7 2.1 1.5 1.9 2.0 2.1 1.8 1.8 1.8 1.5 1.9 1.7 2.0 1.7 1.7 3.6 3.9 4.0 2.7 2.1 2.2
Intensity Change (Log2) – – – -0.04 0.12 -0.17 -0.13 -0.21 -0.38 -0.34 -0.49 -0.36 0.01 0.07 0.02 0.12 0.27 0.21 -0.12 0.09 0.21


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 2.0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -0.4 0 0 0 0 0 0 0 0 0 0 0 0 0.5 0.6
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome -0.9 2.0 0.1 1.1 1.4 -0.6 -1.0 0 0 0 0.9 0.8 0 1.9 1.1
Golgi -2.5 -1.6 -6.7 -7.0 -9.6 -7.6 -7.9 -8.2 -7.7 -1.8 -1.3 -0.3 -2.7 -2.8 -4.1
Mitochondria 6.3 0.8 4.4 3.4 4.5 6.9 7.2 8.4 7.9 4.7 1.8 -0.9 -4.8 -6.9 -6.3
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 2.2 1.7 1.7 1.8 2.5 1.2 1.8 0 0 0 0 0 0
Nucleolus 0 0 0 1.9 0.8 1.1 0.7 1.4 0 0 0 0 0 2.7 2.0
Peroxisomes -1.2 -0.9 -3.0 -2.3 -2.9 -4.1 -4.9 -5.6 -5.0 -1.7 1.6 2.2 -0.1 1.1 0.2
SpindlePole -3.4 -2.4 -3.1 -2.5 -1.9 -3.3 -3.7 -4.0 -2.8 0 -0.6 1.0 2.3 0.5 1.3
Vacuole -2.4 0.4 -1.2 -2.4 -2.9 -4.0 -3.5 -5.0 -4.4 -1.4 -4.1 -3.9 -1.1 -1.3 -0.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.2427 5.3397 4.7454 4.6201 4.3728 4.4512 4.369 5.9091 5.8025 5.2181 5.2075 5.2278 4.2131 5.9424 5.1765 5.4104 5.3931 5.2397
Actin 0.0125 0.0193 0.015 0.0096 0.0103 0.0057 0.0246 0.0266 0.0256 0.0024 0.0087 0.0002 0.033 0.0073 0.013 0.003 0.022 0.0029
Bud 0.0009 0.0018 0.0007 0.001 0.0009 0.0024 0.0009 0.0007 0.0004 0.0008 0.0005 0 0.0006 0.0018 0.0006 0.0007 0.0002 0.0001
Bud Neck 0.0013 0.0005 0.0004 0.0009 0.0005 0.0005 0.0004 0.0004 0.0003 0.0009 0.0002 0 0.0013 0.0003 0.0001 0.0004 0.0001 0.0001
Bud Periphery 0.0021 0.0017 0.0023 0.0019 0.0035 0.0021 0.0021 0.0008 0.0009 0.002 0.001 0 0.0011 0.0033 0.0014 0.001 0.0005 0.0004
Bud Site 0.0049 0.0097 0.0025 0.0114 0.0011 0.0009 0.003 0.0039 0.0009 0.0011 0.0022 0 0.0014 0.0053 0.0029 0.0038 0.0005 0.0002
Cell Periphery 0.0009 0.001 0.0011 0.0006 0.0003 0.0004 0.001 0.0002 0.0003 0.0007 0.0001 0 0.0004 0.0002 0.0002 0.0002 0.0001 0.0001
Cytoplasm 0.0028 0.0014 0.0006 0.0017 0.0002 0.0002 0.0032 0.0003 0.0112 0.0003 0.0001 0.026 0.002 0.0006 0.0004 0.0013 0.0001 0.0004
Cytoplasmic Foci 0.02 0.0214 0.0123 0.0168 0.0077 0.0043 0.0288 0.0056 0.0028 0.0042 0.0169 0.0002 0.0226 0.0084 0.0061 0.0241 0.0157 0.0021
Eisosomes 0.0004 0.0006 0.0006 0.0001 0.0003 0.0002 0.0016 0.0003 0.0005 0.0002 0.0002 0.0001 0.0006 0.0002 0.0002 0.0001 0.0002 0.0002
Endoplasmic Reticulum 0.0027 0.0016 0.0008 0.001 0.0002 0.0001 0.0031 0.0001 0.0018 0.0001 0.0002 0.0013 0.0044 0.0002 0.0004 0.0004 0.0001 0.0004
Endosome 0.0464 0.0479 0.0307 0.049 0.0393 0.0162 0.0265 0.0204 0.0064 0.0313 0.0092 0.0011 0.0503 0.0176 0.0167 0.0254 0.0053 0.0169
Golgi 0.045 0.0688 0.028 0.0373 0.0304 0.0188 0.0206 0.0236 0.0056 0.0232 0.017 0.0031 0.0351 0.0399 0.015 0.0179 0.018 0.0312
Lipid Particles 0.0582 0.0115 0.0063 0.0473 0.017 0.0267 0.0789 0.0118 0.0141 0.0059 0.0869 0.0026 0.046 0.0078 0.0114 0.0076 0.0161 0.0058
Mitochondria 0.6988 0.75 0.8578 0.7612 0.873 0.9058 0.7064 0.8793 0.8902 0.8766 0.819 0.9583 0.7418 0.8853 0.9043 0.8227 0.8776 0.9155
None 0.0015 0.0004 0.0003 0.0003 0.0001 0.0001 0.0096 0.0001 0.0002 0.0001 0.0003 0.0003 0.0037 0.0001 0.0002 0.0019 0.0002 0.0034
Nuclear Periphery 0.0121 0.001 0.0005 0.0089 0.0001 0.0001 0.0146 0.0001 0.0004 0.0001 0.0005 0.0013 0.0063 0.0001 0.0006 0.0004 0.0001 0.0036
Nucleolus 0.0067 0.0008 0.0002 0.0018 0.0004 0.0005 0.0012 0.0011 0.0002 0.0015 0.0006 0 0.0037 0.0002 0.0001 0.0004 0 0.0003
Nucleus 0.0076 0.0006 0.0003 0.0037 0.0002 0.0003 0.0084 0.0003 0.0004 0.0006 0.0002 0.0025 0.0012 0.0001 0.0002 0.0003 0 0.0005
Peroxisomes 0.0378 0.0192 0.0265 0.0137 0.0082 0.0068 0.0495 0.0155 0.0071 0.0105 0.0298 0.0011 0.028 0.0161 0.0186 0.0449 0.0409 0.0058
Punctate Nuclear 0.0032 0.0002 0.0005 0.0021 0.0001 0.0001 0.0043 0 0 0 0.0015 0.0002 0.0042 0.0002 0.0005 0.0008 0.0011 0.001
Vacuole 0.0208 0.0224 0.0054 0.0184 0.0033 0.0039 0.0054 0.0038 0.0087 0.0255 0.0016 0.0002 0.006 0.002 0.0021 0.0205 0.0003 0.0025
Vacuole Periphery 0.0134 0.0182 0.0072 0.0113 0.0028 0.0039 0.0058 0.005 0.0221 0.0121 0.0033 0.0013 0.0063 0.0029 0.005 0.0223 0.0007 0.0066

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 24.4425 20.8096 24.7066 25.4886 33.1999 12.7961 16.964 19.3488 27.8906 20.142
Translational Efficiency 0.9951 0.7697 0.7662 1.0409 0.6958 1.5205 0.8925 0.6626 0.6127 0.6704

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2007 1279 698 98 1081 1455 2442 1020 3088 2734 3140 1118

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 723.31 956.32 1359.71 1435.11 870.02 923.93 1239.96 1316.31 774.67 939.08 1266.58 1326.72
Standard Deviation 110.88 156.27 247.33 202.93 136.35 151.55 224.12 211.71 139.27 154.62 234.82 213.61
Intensity Change Log 2 — 0.402879 0.910613 0.988475 — 0.086735 0.511173 0.597379 — 0.238879 0.706283 0.788131

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002249 0.001795 0.003810 0.018520 0.001307 0.001412 0.002019 0.004395 0.001919 0.001591 0.002417 0.005633
Bud Neck 0.004414 0.002024 0.011432 0.005981 0.001420 0.001933 0.008210 0.001756 0.003366 0.001976 0.008926 0.002127
Bud Site 0.015507 0.006584 0.014048 0.015870 0.004710 0.006876 0.026555 0.009272 0.011727 0.006739 0.023775 0.009850
Cell Periphery 0.000836 0.000175 0.000360 0.000434 0.000248 0.000330 0.001800 0.000549 0.000630 0.000258 0.001480 0.000539
Cytoplasm 0.004246 0.001090 0.000975 0.001143 0.000772 0.001352 0.003030 0.001046 0.003030 0.001229 0.002573 0.001054
Cytoplasmic Foci 0.025880 0.024741 0.021758 0.047018 0.016120 0.025742 0.014119 0.010829 0.022463 0.025273 0.015817 0.014001
Eisosomes 0.000077 0.000061 0.000174 0.000293 0.000046 0.000053 0.000102 0.000110 0.000066 0.000056 0.000118 0.000126
Endoplasmic Reticulum 0.000652 0.000222 0.000371 0.000532 0.000321 0.000344 0.000674 0.000483 0.000536 0.000287 0.000607 0.000487
Endosome 0.031399 0.034798 0.027823 0.021138 0.028673 0.060392 0.041261 0.011921 0.030445 0.048419 0.038274 0.012729
Golgi 0.029745 0.031274 0.023063 0.105587 0.022715 0.063236 0.024303 0.051703 0.027284 0.048284 0.024028 0.056426
Lipid Particles 0.006762 0.002772 0.005465 0.001932 0.004876 0.002256 0.006478 0.001420 0.006102 0.002498 0.006253 0.001465
Mitochondria 0.811129* 0.841229* 0.769870* 0.691637* 0.877938* 0.769204* 0.792564* 0.857113* 0.834516* 0.802898* 0.787519* 0.842608*
Mitotic Spindle 0.008202 0.007541 0.029350 0.010351 0.004685 0.008193 0.008526 0.006117 0.006971 0.007888 0.013155 0.006489
None 0.001028 0.000267 0.001181 0.000722 0.000326 0.000313 0.001405 0.000848 0.000782 0.000291 0.001355 0.000837
Nuclear Periphery 0.000077 0.000140 0.003536 0.000282 0.000207 0.000262 0.001161 0.000443 0.000122 0.000205 0.001689 0.000429
Nuclear Periphery Foci 0.000602 0.000276 0.001989 0.000265 0.000299 0.000507 0.000990 0.000426 0.000496 0.000399 0.001212 0.000412
Nucleolus 0.000718 0.000407 0.002065 0.000208 0.000554 0.000333 0.001056 0.000274 0.000661 0.000368 0.001280 0.000269
Nucleus 0.000473 0.000294 0.000503 0.000104 0.000647 0.000650 0.000518 0.000105 0.000534 0.000484 0.000515 0.000105
Peroxisomes 0.041803 0.027960 0.019485 0.052426 0.021395 0.011984 0.010285 0.006364 0.034659 0.019458 0.012330 0.010402
Vacuole 0.006705 0.008016 0.035595 0.011498 0.004707 0.021959 0.030835 0.013736 0.006006 0.015436 0.031893 0.013539
Vacuole Periphery 0.007496 0.008333 0.027147 0.014058 0.008033 0.022670 0.024107 0.021091 0.007684 0.015963 0.024783 0.020475

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.87 -1.90 -2.69 -2.77 -2.42 -0.26 -1.71 -3.28 -3.22 -2.56 0.90 -1.25 -3.65 -4.08 -3.19
Bud Neck 4.18 -4.71 -0.71 -1.76 2.02 -1.25 -7.98 -0.82 0.39 7.45 3.53 -7.23 2.54 -0.38 8.65
Bud Site 4.73 0.45 -0.10 -1.68 -0.31 -1.41 -9.05 -1.98 -1.05 6.10 3.72 -6.08 0.86 -1.53 5.59
Cell Periphery 6.47 4.03 2.66 -2.29 -0.56 -1.52 -4.39 -1.62 -1.18 3.16 5.29 -3.01 0.51 -1.68 2.94
Cytoplasm 4.47 4.79 4.46 0.07 -0.64 -1.78 -4.04 -0.86 1.05 3.59 3.66 0.70 4.08 0.93 3.44
Cytoplasmic Foci 0.45 1.51 -1.96 -2.07 -2.35 -4.30 1.09 2.79 7.19 2.15 -1.46 4.04 4.24 5.81 1.09
Eisosomes 2.72 -4.31 -4.36 -4.70 -2.21 -1.52 -8.15 -6.26 -5.60 -0.67 2.38 -6.92 -5.72 -6.76 -0.65
Endoplasmic Reticulum 2.18 1.37 0.56 -2.83 -1.28 -0.32 -3.45 -1.51 -1.45 1.70 1.88 -0.47 0.35 -2.47 1.24
Endosome -1.20 1.15 2.67 3.31 1.58 -7.97 -3.89 6.10 14.67 12.44 -7.42 -3.56 10.01 15.86 12.65
Golgi -0.53 2.19 -4.56 -4.46 -4.94 -10.32 -0.62 -6.14 2.13 -6.09 -8.45 1.72 -6.65 -1.77 -7.45
Lipid Particles 3.60 1.04 4.53 1.04 3.69 2.25 -1.26 3.13 1.31 6.54 4.45 -0.17 5.93 1.97 7.34
Mitochondria -2.97 3.10 3.36 4.20 2.12 10.09 8.96 1.94 -7.78 -6.38 4.18 6.25 -0.88 -4.10 -5.71
Mitotic Spindle 0.41 -5.06 -0.70 -0.88 3.84 -2.43 -2.97 -1.00 1.42 1.78 -1.04 -4.68 0.39 1.23 4.43
None 2.04 -0.34 0.81 -3.72 3.10 0.18 -2.92 -5.22 -11.75 1.55 2.01 -1.50 -0.16 -13.18 1.85
Nuclear Periphery -2.96 -4.98 -3.06 -2.08 4.66 -0.44 -5.31 -2.06 -1.58 4.16 -1.43 -7.84 -4.13 -2.72 6.05
Nuclear Periphery Foci 1.87 -4.05 1.89 0.16 6.48 -1.06 -5.67 -0.91 0.38 3.73 0.82 -4.15 0.73 -0.08 5.58
Nucleolus 1.38 -1.51 1.90 0.88 3.70 0.50 -1.18 0.67 0.33 3.09 1.53 -1.10 1.86 0.64 4.35
Nucleus 1.02 -0.01 3.60 1.05 3.41 -0.04 0.23 1.06 1.55 5.15 0.21 0.16 2.33 1.83 5.98
Peroxisomes 3.63 5.85 -0.70 -1.63 -2.20 3.18 4.00 5.13 2.92 2.46 6.10 9.96 8.90 3.92 0.97
Vacuole -1.63 -9.67 -1.26 -0.77 5.03 -10.71 -15.68 -5.16 3.65 7.47 -9.40 -17.79 -4.68 1.17 8.83
Vacuole Periphery -0.78 -8.64 -1.09 -0.95 2.05 -7.40 -9.38 -5.51 0.59 1.24 -7.38 -13.71 -6.24 -2.09 1.91
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative ortholog of human ETF-dH; found in a large supramolecular complex with other mitochondrial dehydrogenases; may have a role in oxidative stress response; ETF-dH is also known as electron transfer flavoprotein dehydrogenase
Localization
Cell Percentages mitochondrion (95%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Cir2

Cir2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cir2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available