Standard name
Human Ortholog
Description Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; linker between TauB and TauA domains; human homolog is TFIIIC-90
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0.05 – – – 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.11 0 0.09 0.05 0.06 – 0.05 0.05 0 0.09 – – – 0.08 0 0.05 0 0 0 0 0 0.06
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0.06 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0.06 0 0
Mitochondria 0.08 0 0 0 0 0.05 0.07 – 0.21 0.13 0.3 0.2 – – – 0 0.06 0 0 0 0 0 0 0
Nucleus 0.96 0.97 0.77 0.95 0.87 0.86 0.8 – 0.7 0.75 0.68 0.7 – – – 0.75 0.82 0.77 0.91 0.95 0.7 0.69 0.71 0.69
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0.06 0 0.11 0.17 – 0.25 0.23 0.4 0.23 – – – 0 0 0.05 0 0 0 0 0 0.05
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.06 0 0 0 – 0 0.05 0 0.05 – – – 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0.11 0 0 0 0 – 0 0 0 0 – – – 0.11 0.11 0.11 0 0 0.09 0 0.11 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 – – – 2 0 0 0 0 1 0 0 0
Bud 0 0 0 0 0 0 0 – 1 1 2 0 – – – 1 0 1 1 1 0 0 1 0
Bud Neck 0 0 0 0 1 0 0 – 1 0 1 0 – – – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 2 4 – 4 3 1 13 – – – 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
Cytoplasm 7 4 4 7 18 13 19 – 11 12 6 22 – – – 17 11 10 2 0 2 0 0 2
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 – – – 6 5 5 0 1 0 0 0 0
Endosome 0 1 0 0 1 4 2 – 0 0 0 1 – – – 3 5 7 1 1 2 0 0 0
Golgi 0 1 0 0 0 0 0 – 0 0 0 0 – – – 0 0 1 1 0 0 0 0 0
Mitochondria 19 0 0 6 1 13 21 – 44 31 45 50 – – – 10 16 3 1 1 0 0 0 0
Nucleus 220 218 27 149 166 214 236 – 145 183 103 180 – – – 169 230 141 214 216 42 11 26 30
Nuclear Periphery 0 0 0 0 0 0 0 – 0 4 1 1 – – – 1 0 0 0 0 0 0 0 0
Nucleolus 9 1 0 9 7 28 50 – 53 57 61 58 – – – 6 5 9 1 1 1 0 1 2
Peroxisomes 0 0 0 0 1 0 0 – 0 0 0 0 – – – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 10 3 5 8 – 9 11 0 14 – – – 4 3 3 0 1 0 0 0 1
Vac/Vac Membrane 0 5 4 1 0 2 3 – 1 3 2 2 – – – 24 30 20 6 2 5 0 4 2
Unique Cell Count 230 225 35 157 191 248 296 208 244 151 256 224 281 184 236 229 61 17 37 45
Labelled Cell Count 255 230 35 182 198 281 343 269 305 222 341 243 305 200 236 229 61 17 37 45


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 7.3 8.6 6.3 7.3 6.2 6.3 – 5.4 5.7 4.8 5.3 – – – 8.9 8.1 8.2 – – –
Std Deviation (1e-4) 0.8 1.1 3.4 1.3 2.3 1.7 1.7 – 1.5 1.6 0.9 1.6 – – – 1.8 1.5 1.6 – – –
Intensity Change (Log2) – – – -0.45 -0.24 -0.48 -0.46 – -0.68 -0.59 -0.84 -0.69 – – – 0.05 -0.09 -0.08 – – –

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT30510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT10510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Bud 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Cytoplasm 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Mitochondria 0 0 0 0 – 3.0 0 0 2.9 – – – 0 0 0
Nucleus 3.4 1.5 1.4 0.4 – -0.9 -0.3 -1.0 -0.8 – – – -0.2 0.7 -0.1
Nuclear Periphery 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Nucleolus 0 0 0 2.6 – 3.4 3.2 0 3.1 – – – 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 – – – 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 – – – 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 – – – 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.7121 1.1558 1.2946 1.0158 1.1405 1.213 0.8577 0.7232 0.9085 0.6979 0.4107 0.8981 0.389 0.2848 0.1726 0.2694 -0.0399 0.232
Actin 0.014 0 0.0017 0 0.0109 0.0018 0.027 0.0018 0.0216 0.0377 0 0.0004 0.0125 0 0.0009 0.0374 0.0002 0.0006
Bud 0.0007 0.0011 0.0002 0 0.0009 0.0005 0.0003 0.0001 0.0003 0.0008 0 0.0001 0.0004 0 0.0002 0.0014 0.0001 0.0009
Bud Neck 0.0067 0.0001 0.0005 0.0001 0.0153 0.0008 0.0006 0.0002 0.0003 0.001 0.0006 0.0007 0.0034 0.0005 0.0004 0.0014 0.0071 0.0007
Bud Periphery 0.0012 0.0002 0.0004 0 0.0045 0.0002 0.0004 0.0002 0.0003 0.0034 0 0.0001 0.0005 0 0.0003 0.0019 0.0001 0.0021
Bud Site 0.007 0.0009 0.0005 0 0.002 0.0001 0.0029 0.0015 0.0076 0.0024 0.0001 0.0001 0.0056 0.0002 0.0019 0.0126 0.0002 0.0025
Cell Periphery 0.0004 0.0001 0.0001 0 0.0007 0 0.0002 0.0002 0.0001 0.0009 0 0 0.0002 0 0.0001 0.0005 0 0
Cytoplasm 0.0032 0.0037 0.0005 0 0.0006 0.0022 0.004 0.0023 0.004 0.0013 0.0001 0.0001 0.0024 0.0004 0.0066 0.0039 0.0004 0.0001
Cytoplasmic Foci 0.0077 0.0006 0.0031 0 0.0049 0.0015 0.0167 0.0002 0.0068 0.0059 0 0.0017 0.0099 0 0.0014 0.0261 0 0.0016
Eisosomes 0.0002 0 0.0001 0 0.0002 0.0001 0.0003 0.0011 0.0002 0.0016 0 0 0.0002 0 0.0001 0.0006 0 0
Endoplasmic Reticulum 0.0022 0.0001 0.0005 0 0.0013 0.0002 0.0017 0.0003 0.0029 0.0012 0 0.0001 0.0019 0 0.0008 0.0066 0.0002 0
Endosome 0.0146 0.0001 0.0035 0 0.0142 0.0041 0.0226 0.0004 0.0057 0.0045 0 0.0061 0.017 0.0002 0.0056 0.0316 0.0002 0.0007
Golgi 0.0066 0 0.0021 0 0.0089 0.0044 0.0051 0.0001 0.0066 0.0075 0 0.0179 0.0024 0 0.0003 0.0168 0 0.0005
Lipid Particles 0.0151 0 0.0049 0 0.0133 0.0033 0.029 0.0003 0.01 0.008 0 0.0038 0.0106 0 0.0004 0.041 0 0.0019
Mitochondria 0.0116 0.0003 0.0065 0.0001 0.0129 0.0074 0.0071 0.0037 0.0086 0.0179 0.0003 0.0039 0.004 0.0002 0.0006 0.0282 0.0003 0.0031
None 0.0019 0.0009 0.0008 0 0.0005 0.0002 0.0175 0.0102 0.0016 0.0016 0 0.0001 0.004 0.0001 0.0036 0.0035 0.0001 0.0002
Nuclear Periphery 0.0223 0.0027 0.0037 0.0002 0.0095 0.0019 0.0181 0.0055 0.0026 0.001 0.0021 0.0006 0.0064 0.0018 0.0033 0.0041 0.005 0.0002
Nucleolus 0.0255 0.0172 0.0184 0.0143 0.0632 0.0403 0.0124 0.0181 0.0206 0.0261 0.0722 0.0218 0.0216 0.0203 0.0268 0.0046 0.0669 0.0437
Nucleus 0.8174 0.9501 0.9369 0.9592 0.7956 0.9065 0.7973 0.9424 0.891 0.861 0.9142 0.9389 0.8658 0.9744 0.9236 0.7463 0.9022 0.9359
Peroxisomes 0.0046 0 0.005 0 0.0045 0.0026 0.0193 0.0003 0.0067 0.0112 0 0.0011 0.0034 0 0.0003 0.0246 0 0.0035
Punctate Nuclear 0.031 0.0212 0.009 0.026 0.0299 0.0214 0.011 0.0109 0.0014 0.0009 0.01 0.0017 0.0258 0.0014 0.0163 0.0038 0.0166 0.0012
Vacuole 0.0036 0.0004 0.0011 0 0.0039 0.0002 0.0054 0.0002 0.0007 0.003 0.0001 0.0005 0.0014 0.0003 0.0046 0.0021 0.0002 0.0003
Vacuole Periphery 0.0026 0.0002 0.0005 0 0.0024 0.0002 0.0011 0.0001 0.0006 0.0013 0 0.0004 0.0006 0.0001 0.002 0.0011 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.8646 11.1644 5.3849 10.6593 12.954 17.4749 9.1718 11.8092 9.6442 15.2051
Translational Efficiency 0.7359 0.5774 0.7723 0.4682 0.4354 0.5454 0.6131 0.4212 0.5115 0.5358

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
636 958 510 1266 1616 2195 382 113 2252 3153 892 1379

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 624.30 750.57 1147.49 907.98 767.19 781.91 1080.60 1055.57 726.84 772.39 1118.84 920.07
Standard Deviation 99.49 106.41 146.79 127.19 101.57 106.35 124.86 125.47 119.73 107.34 141.74 133.34
Intensity Change Log 2 — 0.265747 0.878170 0.540421 — 0.027419 0.494177 0.460366 — 0.139238 0.679177 0.496834

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000275 0.000355 0.001475 0.000981 0.000210 0.000179 0.001312 0.001062 0.000228 0.000232 0.001405 0.000987
Bud Neck 0.004390 0.004064 0.019962 0.022467 0.003177 0.006389 0.019000 0.012673 0.003520 0.005683 0.019550 0.021665
Bud Site 0.001684 0.000815 0.001983 0.005135 0.000304 0.001380 0.002385 0.001913 0.000694 0.001209 0.002155 0.004871
Cell Periphery 0.000138 0.000117 0.000065 0.000219 0.000070 0.000095 0.000087 0.000129 0.000090 0.000102 0.000075 0.000212
Cytoplasm 0.020943 0.011978 0.000520 0.014966 0.005255 0.007680 0.002052 0.011253 0.009686 0.008986 0.001177 0.014662
Cytoplasmic Foci 0.002259 0.002251 0.000049 0.001338 0.000674 0.001194 0.000032 0.000048 0.001121 0.001515 0.000042 0.001232
Eisosomes 0.000023 0.000016 0.000046 0.000031 0.000016 0.000014 0.000047 0.000028 0.000018 0.000015 0.000046 0.000031
Endoplasmic Reticulum 0.001359 0.004083 0.005762 0.007418 0.001976 0.002666 0.006996 0.006184 0.001802 0.003097 0.006291 0.007317
Endosome 0.000391 0.000815 0.000178 0.002594 0.000200 0.001066 0.000244 0.000432 0.000254 0.000990 0.000206 0.002417
Golgi 0.000191 0.000353 0.000101 0.001399 0.000189 0.001056 0.000105 0.000088 0.000190 0.000843 0.000103 0.001292
Lipid Particles 0.000808 0.000501 0.000190 0.000487 0.000362 0.000744 0.000149 0.000200 0.000488 0.000670 0.000172 0.000464
Mitochondria 0.001048 0.001813 0.002200 0.003191 0.000698 0.004829 0.001598 0.001398 0.000797 0.003913 0.001942 0.003044
Mitotic Spindle 0.002566 0.002286 0.000348 0.014940 0.002275 0.005172 0.001396 0.030879 0.002358 0.004295 0.000797 0.016246
None 0.026649 0.008750 0.001061 0.006401 0.007283 0.005159 0.003440 0.010060 0.012752 0.006250 0.002080 0.006700
Nuclear Periphery 0.000593 0.000412 0.000324 0.001616 0.000317 0.000864 0.000386 0.001022 0.000395 0.000727 0.000351 0.001567
Nuclear Periphery Foci 0.000616 0.000479 0.000130 0.000766 0.000238 0.000355 0.000110 0.000239 0.000345 0.000393 0.000122 0.000723
Nucleolus 0.062813 0.008096 0.009586 0.004182 0.031540 0.009665 0.011377 0.002496 0.040372 0.009188 0.010353 0.004044
Nucleus 0.871886 0.950690 0.952956 0.899937 0.944228 0.948528 0.946138 0.914224 0.923798 0.949185 0.950036 0.901108
Peroxisomes 0.000383 0.000767 0.000534 0.000321 0.000361 0.000871 0.000393 0.000131 0.000367 0.000839 0.000473 0.000305
Vacuole 0.000753 0.001052 0.002351 0.009803 0.000474 0.001615 0.002590 0.005405 0.000553 0.001444 0.002454 0.009443
Vacuole Periphery 0.000231 0.000306 0.000177 0.001808 0.000150 0.000476 0.000164 0.000136 0.000173 0.000424 0.000171 0.001671

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.77 -10.44 -14.40 -11.00 2.45 1.22 -13.58 -9.04 -9.24 -2.66 0.27 -16.05 -18.07 -17.81 2.06
Bud Neck 0.94 -10.76 -13.02 -13.42 -0.51 -6.30 -8.32 -5.51 -4.53 -0.41 -4.96 -14.12 -15.29 -13.42 -1.16
Bud Site 1.53 -0.90 -4.06 -6.36 -4.24 -3.09 -7.28 -5.91 -4.32 -3.17 -1.66 -7.06 -8.48 -6.84 -4.83
Cell Periphery 0.67 2.65 -0.52 -1.15 -2.96 -1.40 -0.63 -2.88 -1.95 -2.49 -0.75 1.09 -2.48 -1.99 -3.08
Cytoplasm 2.68 6.38 2.10 -1.00 -8.65 -1.87 3.42 -1.20 -0.49 -2.24 0.62 7.43 -2.13 -2.86 -8.68
Cytoplasmic Foci -0.00 2.96 2.08 1.61 -2.93 -1.17 1.80 1.58 4.67 -3.12 -0.82 3.21 1.37 2.39 -3.03
Eisosomes 3.84 -8.56 -8.39 -12.02 1.56 2.24 -11.25 -6.63 -6.98 -2.08 4.00 -15.65 -14.79 -16.89 1.17
Endoplasmic Reticulum -6.13 -7.18 -17.08 -11.52 -5.99 -3.54 -10.13 -7.56 -7.01 -3.46 -6.63 -12.09 -20.72 -16.89 -6.43
Endosome -1.17 2.62 -3.27 -1.50 -4.01 -3.42 -2.20 -4.10 0.09 -3.71 -3.56 0.67 -4.06 -1.37 -4.15
Golgi -0.66 1.98 -1.96 -0.86 -2.39 -2.33 0.60 -0.25 2.40 -3.29 -2.42 0.84 -1.85 0.69 -2.44
Lipid Particles 0.65 1.36 0.64 -0.04 -2.08 -1.31 1.52 -1.56 0.35 -3.92 -0.79 1.89 -0.14 0.74 -2.69
Mitochondria -0.85 -2.35 -6.52 -1.38 -1.30 -4.26 -3.23 -6.68 2.44 -1.31 -4.29 -3.89 -7.82 1.22 -2.09
Mitotic Spindle 0.72 2.06 -4.67 -5.30 -6.45 -1.87 0.19 -2.44 -2.24 -2.46 -1.27 1.55 -5.94 -5.39 -6.60
None 5.18 8.55 7.05 2.00 -6.30 1.81 4.27 0.75 -0.55 -2.14 4.96 9.87 6.14 1.14 -5.30
Nuclear Periphery 2.90 3.22 -8.19 -11.72 -12.46 -3.90 -3.02 -5.74 -4.25 -5.24 -2.50 0.18 -13.09 -9.84 -13.23
Nuclear Periphery Foci 1.13 3.26 -0.66 -1.81 -4.15 -0.80 1.92 -2.34 -1.45 -3.25 -0.15 3.28 -2.86 -2.46 -4.67
Nucleolus 11.57 10.53 12.36 2.36 4.71 10.73 7.90 13.50 4.79 3.91 15.58 13.05 17.68 4.52 5.58
Nucleus -9.69 -9.49 -3.03 8.76 8.66 -0.89 0.43 4.11 4.31 3.95 -6.72 -5.36 5.50 10.70 9.71
Peroxisomes -1.28 -2.06 2.06 1.77 4.42 -1.45 -0.04 1.10 1.99 2.75 -1.84 -1.17 1.45 2.51 4.62
Vacuole 1.70 0.11 -5.41 -8.04 -6.31 -3.48 -3.58 -3.72 -3.54 -3.17 -0.58 -3.22 -8.55 -8.55 -6.94
Vacuole Periphery -0.68 0.62 -1.87 -1.56 -2.01 -2.98 -0.34 -1.57 2.50 -1.51 -3.02 -0.17 -2.08 -1.15 -2.07
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; linker between TauB and TauA domains; human homolog is TFIIIC-90
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Tfc8

Tfc8


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tfc8-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available