Standard name
Human Ortholog
Description UbiB family protein; contains transmembrane domain and mitochondrial targeting sequence; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.05 0.05 0 0 0.05
Bud 0 0 0.05 0.05 0 0 0 0.05 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0.05 0 0 0 0 0 0
Cytoplasm 0.15 0.18 0.15 0.12 0.15 0.08 0.12 0.14 0.07 0.1 0.13 0.12 0.35 0.44 0.55 0.37 0.3 0.33 0 0.06 0 0 0.06 0
Endoplasmic Reticulum 0 0.05 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0.07 0.07 0.06 0 0 0 0 0 0
Endosome 0 0.05 0 0.05 0.15 0 0 0 0 0 0 0 0.12 0.12 0.19 0.2 0.17 0.16 0.08 0.08 0.09 0 0.06 0.06
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.88 0.72 0.74 0.87 0.73 0.88 0.86 0.83 0.95 0.91 0.82 0.86 0.55 0.28 0.16 0.15 0.1 0.09 0.69 0.61 0.66 0.7 0.63 0.57
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.1 0 0.07 0 0 0 0 0 0 0 0.06 0 0.07 0.22 0.08 0.1 0 0 0.07 0 0 0
SpindlePole 0 0 0.05 0 0.07 0 0.08 0.09 0 0 0 0 0 0 0 0.09 0.12 0.14 0 0 0 0 0 0
Vac/Vac Membrane 0.06 0.12 0 0 0.08 0 0 0.05 0 0 0 0 0.09 0.16 0.14 0.16 0.18 0.13 0.06 0.09 0 0 0.07 0.11
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 3 0 0 0 0 0 0 0 0 0 0 0 0 1 2 7 2 8 16 0 5 7
Bud 3 6 12 7 10 3 16 24 9 11 4 2 1 5 0 7 4 1 1 2 0 1 2 1
Bud Neck 0 0 0 0 1 0 1 2 0 0 0 0 0 0 0 0 2 0 2 2 4 1 3 6
Bud Site 1 0 1 1 0 5 4 4 6 5 0 0 0 0 0 1 0 0 – – – – – –
Cell Periphery 0 3 4 3 1 4 2 1 1 2 0 1 6 3 1 14 12 6 0 0 1 0 1 1
Cytoplasm 20 27 34 18 36 30 50 62 22 43 8 7 48 53 89 109 57 41 1 10 1 1 9 3
Endoplasmic Reticulum 0 7 3 3 0 4 2 2 3 10 5 0 2 2 3 20 13 7 3 3 2 1 1 1
Endosome 5 7 7 7 38 4 6 13 0 0 0 0 16 15 30 59 33 20 12 13 26 3 8 8
Golgi 0 1 0 0 0 2 0 0 0 0 0 0 1 0 0 0 1 1 1 3 9 2 1 4
Mitochondria 119 106 170 132 180 328 362 370 300 402 51 48 75 34 25 44 19 11 105 111 196 55 93 90
Nucleus 6 1 1 0 1 8 8 15 7 4 1 0 0 1 0 2 7 2 0 0 0 1 1 0
Nuclear Periphery 0 0 1 0 0 3 1 2 2 10 1 1 0 0 0 0 0 0 3 0 2 0 0 0
Nucleolus 7 0 0 1 0 2 3 3 1 2 0 0 0 0 0 0 0 0 1 0 0 1 2 0
Peroxisomes 1 2 23 6 17 5 5 9 1 0 1 0 8 4 12 66 15 13 2 5 21 2 2 4
SpindlePole 0 2 11 2 16 13 32 38 14 16 2 0 4 0 1 26 23 17 1 1 3 0 3 2
Vac/Vac Membrane 8 18 5 3 20 12 17 21 10 13 1 1 13 19 22 47 34 16 9 16 5 1 9 17
Unique Cell Count 136 147 231 151 246 372 419 444 317 443 62 56 137 121 161 298 189 124 152 184 298 79 148 158
Labelled Cell Count 170 182 275 183 320 423 509 566 376 518 74 60 174 136 183 396 222 142 152 184 298 79 148 158


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.0 4.7 4.6 4.2 4.1 3.8 3.2 3.7 3.4 2.9 3.6 3.4 4.9 4.9 4.9 5.6 6.5 6.3 4.4 4.9 5.8
Std Deviation (1e-4) 0.5 0.7 1.2 0.9 1.2 1.2 0.9 1.2 0.9 0.7 1.5 1.3 1.0 1.3 1.4 1.7 1.8 1.2 1.5 1.8 1.9
Intensity Change (Log2) – – – -0.14 -0.15 -0.28 -0.52 -0.31 -0.43 -0.64 -0.35 -0.42 0.11 0.08 0.1 0.29 0.51 0.46 -0.07 0.1 0.33

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 5.2 5.6 4.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.8529 1.0118 0.5438 0.9635 0.2925 0.7866 1.8052 2.1708 2.1774 1.4882 2.2336 1.8077 3.5648 3.3797 3.2341 3.2775 3.1271 3.4774
Actin 0.0879 0.0283 0.0305 0.0168 0.182 0.0224 0.056 0.046 0.0203 0.0472 0.0406 0.0074 0.0382 0.0111 0.0153 0.0151 0.0459 0.0178
Bud 0.0025 0.0063 0.0096 0.0018 0.0018 0.0027 0.002 0.0038 0.0052 0.0091 0.0048 0.0028 0.0018 0.0053 0.0055 0.0105 0.0027 0.0016
Bud Neck 0.0017 0.0044 0.0046 0.0013 0.006 0.0236 0.0064 0.0038 0.0013 0.002 0.0011 0.0034 0.0025 0.0051 0.0055 0.0095 0.0014 0.0138
Bud Periphery 0.0037 0.0094 0.0389 0.0067 0.0022 0.0124 0.005 0.0104 0.0141 0.0331 0.007 0.0079 0.0032 0.0098 0.022 0.0392 0.0058 0.0052
Bud Site 0.0073 0.1246 0.0326 0.003 0.0041 0.0041 0.0516 0.0689 0.0112 0.01 0.0117 0.0009 0.0152 0.0475 0.0404 0.0098 0.0097 0.003
Cell Periphery 0.0015 0.0092 0.0061 0.051 0.0002 0.0114 0.0052 0.0075 0.0042 0.0073 0.0005 0.001 0.0027 0.0071 0.0071 0.0117 0.0015 0.0039
Cytoplasm 0.0138 0.067 0.0612 0.1197 0.0201 0.0713 0.0886 0.0886 0.0785 0.1058 0.0232 0.0549 0.0662 0.1191 0.0651 0.0679 0.0207 0.0617
Cytoplasmic Foci 0.1588 0.0455 0.1609 0.0343 0.1907 0.1063 0.0781 0.1033 0.0636 0.0985 0.1394 0.0775 0.1046 0.1101 0.0897 0.0675 0.0921 0.0797
Eisosomes 0.0068 0.0021 0.001 0.0022 0.0007 0.0018 0.0015 0.0036 0.0026 0.0016 0.0003 0.0006 0.0015 0.0014 0.002 0.0018 0.0003 0.0021
Endoplasmic Reticulum 0.0057 0.0202 0.0045 0.0431 0.0008 0.0235 0.0673 0.0119 0.0073 0.0056 0.001 0.0039 0.0144 0.0042 0.0037 0.0058 0.0027 0.0146
Endosome 0.1446 0.1222 0.1108 0.14 0.0485 0.0894 0.1478 0.1006 0.0812 0.0589 0.0816 0.091 0.1534 0.1407 0.1405 0.1598 0.1761 0.1387
Golgi 0.0581 0.0337 0.0672 0.0735 0.0453 0.0749 0.0467 0.0591 0.0557 0.0428 0.0571 0.0558 0.0831 0.0657 0.0726 0.0528 0.0766 0.0871
Lipid Particles 0.0465 0.0415 0.0196 0.0159 0.0929 0.0309 0.0421 0.0125 0.0196 0.0186 0.0107 0.0147 0.0397 0.0216 0.0178 0.0099 0.0097 0.0181
Mitochondria 0.154 0.2561 0.3248 0.4444 0.0188 0.3057 0.1741 0.2428 0.3724 0.4526 0.2931 0.4622 0.322 0.3297 0.4016 0.4244 0.4617 0.4077
None 0.0459 0.1709 0.0695 0.0163 0.1609 0.1418 0.1079 0.1649 0.2025 0.028 0.2579 0.165 0.0869 0.0842 0.0575 0.069 0.0541 0.0931
Nuclear Periphery 0.0399 0.0051 0.0007 0.0029 0.0021 0.0077 0.0179 0.0015 0.0022 0.0018 0.0008 0.001 0.0085 0.0008 0.0008 0.0011 0.0006 0.0033
Nucleolus 0.0121 0.0037 0.0009 0.0005 0.0044 0.0016 0.0018 0.0008 0.0011 0.0006 0.0005 0.0005 0.0006 0.0014 0.001 0.0009 0.0004 0.0007
Nucleus 0.0557 0.0045 0.0012 0.0015 0.0022 0.0017 0.0038 0.0013 0.0034 0.0014 0.0006 0.0008 0.0021 0.002 0.001 0.0014 0.0007 0.0011
Peroxisomes 0.0434 0.0114 0.0347 0.0094 0.1773 0.0427 0.0465 0.041 0.037 0.0503 0.0589 0.037 0.0351 0.0172 0.0299 0.0178 0.0156 0.0318
Punctate Nuclear 0.0107 0.0038 0.0022 0.0006 0.0364 0.0013 0.0187 0.0012 0.0007 0.0034 0.0008 0.0011 0.0015 0.002 0.0041 0.001 0.0006 0.0006
Vacuole 0.0636 0.0238 0.0128 0.0086 0.0017 0.0165 0.0234 0.0217 0.0106 0.0164 0.0048 0.0067 0.0118 0.0105 0.0112 0.0161 0.0145 0.0097
Vacuole Periphery 0.0357 0.0061 0.0057 0.0066 0.0008 0.0064 0.0076 0.0046 0.0051 0.0049 0.0035 0.0041 0.0051 0.0035 0.0054 0.0069 0.0066 0.0046

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.8692 4.4972 4.4494 6.1769 2.1742 5.0279 7.9574 6.8199 8.0989 7.3105
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1985 1622 230 1689 1842 3133 123 1740 3827 4755 353 3429

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1040.47 1134.80 1281.62 1453.69 1066.63 1166.83 1438.65 1522.71 1053.06 1155.90 1336.34 1488.71
Standard Deviation 147.58 191.72 177.84 237.66 148.96 194.28 167.78 220.37 148.83 194.00 189.77 231.63
Intensity Change Log 2 — 0.125203 0.300733 0.482484 — 0.129535 0.431656 0.513581 — 0.127397 0.368491 0.498310

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000152 0.000154 0.000986 0.000779 0.000208 0.000091 0.000435 0.000906 0.000179 0.000112 0.000794 0.000843
Bud Neck 0.000689 0.000450 0.001516 0.001195 0.000863 0.000774 0.002621 0.001365 0.000773 0.000664 0.001901 0.001281
Bud Site 0.015488 0.014927 0.021292 0.016063 0.016413 0.011662 0.026942 0.020241 0.015933 0.012776 0.023260 0.018183
Cell Periphery 0.000161 0.000130 0.000284 0.000467 0.000201 0.000110 0.000144 0.000543 0.000180 0.000117 0.000235 0.000505
Cytoplasm 0.814329 0.881317 0.805975 0.913140 0.778159 0.872458 0.470502 0.867676 0.796920 0.875480 0.689082 0.890070
Cytoplasmic Foci 0.119530 0.057238 0.074639 0.014251 0.137923 0.057024 0.113799 0.017585 0.128383 0.057097 0.088284 0.015943
Eisosomes 0.000009 0.000003 0.000011 0.000004 0.000013 0.000008 0.000023 0.000005 0.000011 0.000006 0.000015 0.000004
Endoplasmic Reticulum 0.003210 0.001512 0.002612 0.000138 0.004504 0.001057 0.001372 0.000193 0.003833 0.001212 0.002180 0.000165
Endosome 0.003575 0.003718 0.009370 0.001094 0.007359 0.002402 0.020154 0.003301 0.005396 0.002851 0.013128 0.002213
Golgi 0.010675 0.007928 0.004656 0.003398 0.011728 0.007341 0.000803 0.004566 0.011182 0.007541 0.003313 0.003991
Lipid Particles 0.000841 0.000499 0.002353 0.002996 0.001219 0.000434 0.002965 0.002831 0.001023 0.000456 0.002566 0.002913
Mitochondria 0.001427 0.000300 0.000034 0.000694 0.000509 0.000901 0.000009 0.000344 0.000985 0.000696 0.000025 0.000516
Mitotic Spindle 0.000605 0.001660 0.001585 0.003300 0.000334 0.000637 0.000507 0.003836 0.000474 0.000986 0.001210 0.003572
None 0.002753 0.000755 0.000638 0.000498 0.000694 0.001381 0.000076 0.000275 0.001762 0.001167 0.000442 0.000384
Nuclear Periphery 0.000051 0.000018 0.000082 0.000019 0.000039 0.000025 0.000123 0.000041 0.000045 0.000022 0.000096 0.000030
Nuclear Periphery Foci 0.000360 0.000705 0.007245 0.001224 0.000392 0.000100 0.007224 0.001049 0.000376 0.000306 0.007237 0.001135
Nucleolus 0.000129 0.000165 0.000041 0.000137 0.000069 0.000089 0.000065 0.000147 0.000100 0.000115 0.000049 0.000142
Nucleus 0.004877 0.003849 0.010830 0.007343 0.003656 0.005363 0.007103 0.005172 0.004290 0.004846 0.009531 0.006241
Peroxisomes 0.000368 0.000505 0.000376 0.000619 0.000437 0.000387 0.001361 0.000742 0.000401 0.000427 0.000719 0.000681
Vacuole 0.015057 0.019181 0.054273 0.031217 0.028365 0.031773 0.342581 0.066698 0.021462 0.027477 0.154732 0.049221
Vacuole Periphery 0.005713 0.004987 0.001202 0.001423 0.006915 0.005985 0.001191 0.002486 0.006292 0.005644 0.001198 0.001963

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.12 -6.90 -3.29 -3.27 0.96 7.27 -3.71 -1.88 -2.24 -1.16 5.41 -7.43 -3.29 -3.63 0.03
Bud Neck 3.59 -5.62 -4.27 -5.67 0.66 0.87 -6.16 -4.17 -4.77 3.65 1.71 -8.03 -6.00 -6.87 2.71
Bud Site 0.41 -2.96 -0.43 -0.78 2.50 5.02 -2.00 -1.74 -5.18 1.47 3.99 -3.36 -1.56 -4.72 2.52
Cell Periphery 2.61 -4.04 -5.72 -6.33 -2.81 7.21 3.67 -8.13 -10.80 -9.45 7.17 -2.52 -9.44 -11.53 -6.47
Cytoplasm -10.27 1.45 -14.31 -3.03 -7.51 -15.97 11.84 -10.37 3.86 -14.64 -18.41 7.57 -16.83 0.22 -12.66
Cytoplasmic Foci 14.65 7.13 28.96 14.89 10.67 20.26 3.09 31.87 19.70 10.90 24.94 7.95 42.91 25.06 14.85
Eisosomes 7.19 -2.13 7.19 -1.57 6.01 1.64 -4.18 7.09 0.98 8.21 2.19 -3.77 9.63 0.84 9.57
Endoplasmic Reticulum 2.52 0.65 5.02 4.85 2.47 4.20 4.07 5.45 4.12 5.42 5.00 2.27 7.40 6.18 3.02
Endosome -0.37 -2.76 10.07 6.93 4.01 10.63 -4.04 7.13 -1.64 5.75 9.01 -4.18 10.22 2.90 6.25
Golgi 2.99 4.08 8.23 4.29 0.79 6.66 21.80 8.18 3.71 -3.69 7.07 7.85 11.57 5.81 -0.29
Lipid Particles 3.92 -5.06 -5.84 -6.64 -2.04 9.05 -3.89 -6.79 -10.24 -0.31 9.60 -6.18 -8.57 -10.97 -1.98
Mitochondria 2.66 3.31 1.33 -0.59 -1.15 -1.99 4.04 1.19 2.97 -2.07 1.16 4.23 1.65 0.98 -1.67
Mitotic Spindle -1.54 -3.20 -2.81 -1.59 -1.87 -0.99 -1.38 -3.39 -2.95 -3.12 -1.64 -3.79 -4.35 -3.40 -3.23
None 3.35 3.29 3.73 2.41 0.18 -2.67 5.22 3.25 4.60 -3.13 1.72 3.71 4.30 4.76 0.03
Nuclear Periphery 1.64 -1.91 1.03 -2.30 5.19 0.91 -5.26 -0.84 -2.46 5.44 1.73 -4.25 0.30 -2.78 6.69
Nuclear Periphery Foci -2.54 -8.86 -8.43 -4.93 7.21 9.37 -6.20 -7.23 -9.92 5.41 1.25 -10.82 -11.08 -11.22 9.13
Nucleolus -0.50 2.22 -0.56 0.15 -3.64 -3.05 0.46 -6.95 -5.01 -6.67 -0.52 2.41 -2.18 -1.42 -6.28
Nucleus 1.43 -4.12 -5.28 -6.72 1.81 -5.91 -3.46 -7.35 -3.97 0.47 -1.64 -5.21 -8.27 -7.63 2.08
Peroxisomes -0.92 -0.28 -2.77 -0.54 -2.30 1.20 -2.92 -2.94 -3.34 1.90 -0.54 -2.72 -4.06 -2.74 0.34
Vacuole -2.53 -6.53 -12.92 -9.82 3.11 -1.81 -13.01 -14.71 -13.74 10.72 -4.59 -11.61 -18.92 -15.48 8.21
Vacuole Periphery 1.03 8.02 7.69 6.21 -0.23 1.20 8.51 5.99 6.20 -2.22 1.25 11.42 9.36 9.16 -1.72
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description UbiB family protein; contains transmembrane domain and mitochondrial targeting sequence; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-4

Mco76

Mco76


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mco76-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available