Standard name
Human Ortholog
Description Heme-binding protein; involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0.05 0.05 0 0.07 0 0 0.05 0.06 0.09 0.07 0 0 0 0 0 0
Cytoplasm 0.67 0.69 0.79 0.74 0.84 0.71 0.62 0.55 0.57 0.59 0.59 0.62 0.81 0.91 0.93 0.73 0.71 0.73 0.26 0.51 0.4 0.38 0.53 0.51
Endoplasmic Reticulum 0.33 0.28 0.17 0 0.14 0.2 0.2 0.15 0.19 0.2 0.15 0.21 0.17 0.08 0.08 0 0 0 0.56 0.28 0.51 0.38 0.21 0.21
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.05 0 0 0.05 0 0.1 0.05 0.12 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.06 0 0.25 0 0.06 0.15 0.27 0.18 0.15 0.12 0.11 0.05 0 0 0.23 0.25 0.21 0.06 0.09 0 0.12 0.14 0.12
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 2 5 0 2 7 2 2 0 0 0 0 1 0 0 2 1 3 5 10
Bud 0 2 2 3 5 9 7 11 7 7 7 9 4 2 0 1 1 0 0 2 0 4 10 25
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 3 6 13
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 2 0 2 3 14 12 15 17 25 6 24 11 22 40 17 22 12 0 1 0 2 3 6
Cytoplasm 18 109 55 143 335 299 354 399 212 319 119 211 351 583 789 193 174 123 22 102 37 93 215 297
Endoplasmic Reticulum 9 44 12 5 54 85 117 112 71 110 31 70 75 51 68 5 1 2 48 55 48 94 85 123
Endosome 0 0 0 1 1 0 0 1 0 0 1 0 0 2 1 4 0 0 0 1 0 2 1 6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 1 2 0
Mitochondria 0 0 1 10 3 14 30 29 36 26 25 31 0 0 0 1 0 0 3 4 0 8 9 10
Nucleus 1 3 1 1 0 8 4 8 7 7 6 6 8 4 5 8 3 7 0 0 0 0 3 3
Nuclear Periphery 0 1 1 1 0 1 5 12 0 8 5 2 0 0 0 0 0 0 0 1 0 1 0 3
Nucleolus 0 0 0 0 1 0 1 3 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3
Vac/Vac Membrane 0 10 2 49 11 24 87 195 67 79 24 37 23 16 9 62 61 36 4 17 3 30 59 69
Unique Cell Count 27 158 70 193 399 421 573 727 371 537 200 340 434 639 846 264 245 168 86 201 95 248 408 582
Labelled Cell Count 28 171 74 215 414 456 622 785 419 589 227 393 472 681 912 292 263 180 86 201 95 248 408 582


Cytoplasm, Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.4 7.7 6.1 6.6 7.9 8.4 8.2 8.9 8.6 9.4 8.9 9.1 8.2 8.3 8.6 11.5 11.9 12.4 8.7 8.5 9.4
Std Deviation (1e-4) 1.1 2.2 1.4 2.5 2.0 1.8 1.7 2.1 2.4 2.3 2.4 2.4 1.1 1.6 1.3 3.6 4.1 3.6 1.5 1.4 2.0
Intensity Change (Log2) – – – 0.12 0.37 0.46 0.44 0.54 0.5 0.62 0.55 0.58 0.42 0.44 0.49 0.91 0.96 1.03 0.52 0.49 0.62

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.7 1.1 -1.3 -2.8 -3.8 -3.4 -3.1 -2.9 -2.6 0.5 3.4 4.4 -0.9 -1.3 -0.9
Endoplasmic Reticulum 0 -0.8 0.6 0.6 -0.4 0.4 0.7 -0.3 0.7 0 -2.6 -2.6 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 2.3 0 2.7 2.2 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 4.1 0 0 2.8 4.4 3.2 2.7 2.2 2.1 0 0 0 3.9 4.1 3.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.0817 6.8126 6.2048 6.0653 5.161 5.9915 3.9148 4.373 3.9786 4.3129 3.9115 4.1903 2.5317 2.8673 2.9447 2.4244 2.726 2.7737
Actin 0.0021 0.0023 0.0009 0.002 0.0003 0.0005 0.0185 0.0007 0.0078 0.034 0.0016 0.0008 0.043 0.0007 0.0129 0.0108 0.0013 0.014
Bud 0.0001 0.0003 0.0001 0.0006 0 0.0001 0.0008 0.0003 0.0003 0.0007 0.0001 0.0001 0.0003 0 0.0003 0.0003 0.0001 0.0001
Bud Neck 0.0007 0.0035 0.0011 0.0036 0.001 0.003 0.0025 0.0004 0.0007 0.0081 0.002 0.002 0.001 0.0002 0.0005 0.0049 0.0067 0.0014
Bud Periphery 0.0001 0.0002 0.0001 0.0008 0 0.0001 0.0015 0.0002 0.0004 0.0007 0.0001 0.0001 0.0006 0 0.0005 0.0003 0.0001 0.0003
Bud Site 0.0017 0.0258 0.0041 0.0007 0.0001 0.0001 0.0043 0.0062 0.0016 0.0224 0.0002 0.0001 0.0017 0.0007 0.0013 0.0048 0.0006 0.0002
Cell Periphery 0.0003 0.0014 0.0004 0.0004 0.0002 0.0001 0.0009 0.0012 0.001 0.0005 0.0007 0.0002 0.0004 0.0004 0.0006 0.001 0.0002 0.0001
Cytoplasm 0.5712 0.6401 0.515 0.601 0.5684 0.6248 0.5165 0.6393 0.5161 0.5726 0.7224 0.586 0.5108 0.7376 0.6328 0.6619 0.5284 0.675
Cytoplasmic Foci 0.0063 0.0056 0.0033 0.0017 0.0028 0.0045 0.0145 0.0048 0.0265 0.0229 0.007 0.0065 0.0054 0.0028 0.0059 0.0147 0.0183 0.004
Eisosomes 0.0001 0.0001 0 0 0 0 0.0002 0.0001 0.0002 0.0001 0.0001 0 0.0007 0 0.0001 0.0001 0 0.0001
Endoplasmic Reticulum 0.2658 0.1971 0.3742 0.2632 0.3379 0.2515 0.2892 0.2308 0.2922 0.2147 0.1425 0.3 0.2745 0.2069 0.2895 0.2316 0.3238 0.2339
Endosome 0.0084 0.0078 0.0056 0.0039 0.0047 0.0109 0.0186 0.0058 0.0333 0.0132 0.0114 0.0137 0.0141 0.0043 0.0073 0.0084 0.0066 0.0062
Golgi 0.0007 0.0005 0.0002 0.0002 0.0001 0.0005 0.0068 0.0004 0.0099 0.004 0.0004 0.0007 0.0072 0.0003 0.0034 0.0021 0.0051 0.0038
Lipid Particles 0.0019 0.001 0.0007 0.0006 0.0011 0.0008 0.0068 0.0023 0.0106 0.0061 0.0016 0.0015 0.0259 0.0013 0.0037 0.0032 0.0274 0.0036
Mitochondria 0.0024 0.0003 0.0002 0.0002 0.0001 0.0003 0.0022 0.0001 0.0039 0.001 0.0001 0.0066 0.0061 0.0001 0.0073 0.0004 0.0339 0.0052
None 0.0718 0.0363 0.0349 0.0398 0.0166 0.04 0.0712 0.0797 0.0644 0.0397 0.077 0.0567 0.0379 0.0254 0.0073 0.0421 0.0039 0.0295
Nuclear Periphery 0.0221 0.0225 0.0255 0.0302 0.0125 0.0238 0.0155 0.0114 0.014 0.0121 0.0123 0.0096 0.0217 0.0097 0.0133 0.0063 0.0042 0.0089
Nucleolus 0.0006 0.0008 0.0003 0.0003 0.0001 0.0002 0.0004 0.0002 0.0001 0.0009 0.0003 0.0002 0.0012 0 0.0001 0.0001 0.0002 0.0001
Nucleus 0.0309 0.0392 0.0244 0.0433 0.0289 0.0314 0.011 0.0085 0.0038 0.0054 0.0111 0.0086 0.0332 0.0067 0.0044 0.0032 0.0026 0.01
Peroxisomes 0.0007 0.0002 0.0001 0 0 0.0001 0.0044 0.0001 0.0041 0.0204 0.0001 0.0001 0.0035 0 0.0026 0.0004 0.0345 0.0008
Punctate Nuclear 0.0076 0.0094 0.0053 0.0038 0.0215 0.004 0.0035 0.0015 0.0037 0.017 0.0042 0.0023 0.0053 0.0007 0.0044 0.0011 0.0004 0.0008
Vacuole 0.004 0.0053 0.003 0.0031 0.0032 0.0029 0.008 0.0057 0.0045 0.0031 0.0047 0.0036 0.0043 0.0021 0.0015 0.0018 0.0013 0.0016
Vacuole Periphery 0.0005 0.0003 0.0003 0.0003 0.0002 0.0003 0.0026 0.0002 0.0009 0.0004 0.0003 0.0005 0.0011 0.0001 0.0003 0.0002 0.0002 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.8373 25.7876 23.9194 25.5927 23.376 43.2468 19.0122 22.7308 31.7684 24.4108
Translational Efficiency 1.9608 1.4327 1.0841 1.2386 1.5814 1.2065 1.6398 1.6629 0.8488 1.6151

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1540 898 1444 558 267 1466 752 1438 1807 2364 2196 1996

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 622.95 703.89 974.04 1587.85 661.77 687.77 968.76 1455.52 628.69 693.89 972.23 1492.51
Standard Deviation 128.47 125.56 239.14 333.00 220.13 172.34 259.85 378.27 146.34 156.43 246.44 370.97
Intensity Change Log 2 — 0.176234 0.644865 1.349886 — 0.055596 0.549809 1.137133 — 0.115353 0.596683 1.244216

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000287 0.000159 0.000789 0.005378 0.000156 0.000212 0.001552 0.002815 0.000268 0.000192 0.001051 0.003532
Bud Neck 0.009864 0.024998 0.005874 0.017432 0.006656 0.025120 0.009857 0.011859 0.009390 0.025074 0.007238 0.013417
Bud Site 0.009151 0.011671 0.010391 0.035435 0.002957 0.011879 0.020106 0.032651 0.008236 0.011800 0.013718 0.033429
Cell Periphery 0.002199 0.000169 0.001252 0.011228 0.001196 0.000671 0.001774 0.002184 0.002050 0.000480 0.001431 0.004713
Cytoplasm 0.351060 0.341491 0.388308 0.312506 0.353128 0.346346 0.492277 0.410071 0.351366 0.344502 0.423911 0.382796
Cytoplasmic Foci 0.119988 0.129305 0.015792 0.019518 0.144185 0.134906 0.039835 0.028432 0.123563 0.132778 0.024026 0.025940
Eisosomes 0.002713 0.000084 0.000100 0.000250 0.001232 0.000938 0.000119 0.000148 0.002494 0.000614 0.000106 0.000176
Endoplasmic Reticulum 0.218852 0.001806 0.159556 0.093467 0.121721 0.108400 0.098197 0.104220 0.204500 0.067909 0.138544 0.101214
Endosome 0.009783 0.048494 0.004838 0.008631 0.019528 0.031497 0.010208 0.013123 0.011223 0.037953 0.006677 0.011867
Golgi 0.009804 0.001417 0.000457 0.001774 0.002067 0.004736 0.001766 0.005651 0.008661 0.003475 0.000905 0.004567
Lipid Particles 0.052263 0.007287 0.005147 0.131139 0.046180 0.044440 0.017129 0.037180 0.051364 0.030327 0.009250 0.063447
Mitochondria 0.010937 0.003090 0.000709 0.000356 0.000951 0.006382 0.000915 0.002248 0.009461 0.005132 0.000780 0.001719
Mitotic Spindle 0.000236 0.001911 0.001144 0.009011 0.000170 0.001685 0.009763 0.014469 0.000227 0.001771 0.004095 0.012943
None 0.045879 0.005257 0.020115 0.001826 0.040379 0.026385 0.003732 0.021245 0.045067 0.018359 0.014505 0.015816
Nuclear Periphery 0.006154 0.000911 0.012119 0.001802 0.007356 0.006141 0.004658 0.003020 0.006332 0.004154 0.009564 0.002679
Nuclear Periphery Foci 0.008053 0.001886 0.036330 0.088683 0.030975 0.006250 0.059601 0.061440 0.011440 0.004592 0.044299 0.069056
Nucleolus 0.001691 0.002607 0.000967 0.000266 0.004941 0.003009 0.000460 0.000758 0.002171 0.002856 0.000793 0.000621
Nucleus 0.098508 0.067379 0.284957 0.074433 0.155804 0.096823 0.094899 0.069692 0.106974 0.085638 0.219873 0.071017
Peroxisomes 0.006624 0.004279 0.000294 0.000318 0.002062 0.004936 0.000560 0.000492 0.005950 0.004687 0.000385 0.000444
Vacuole 0.033485 0.341766 0.050586 0.186151 0.057295 0.135966 0.132111 0.174833 0.037003 0.214142 0.078503 0.177997
Vacuole Periphery 0.002468 0.004032 0.000275 0.000394 0.001061 0.003278 0.000483 0.003470 0.002260 0.003564 0.000346 0.002610

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.07 -4.17 -5.13 -5.26 -4.45 -0.78 -7.16 -6.68 -6.54 -2.90 1.61 -7.42 -8.24 -8.40 -5.86
Bud Neck -5.51 2.99 -6.87 1.25 -10.42 -7.81 -2.70 -4.30 5.73 -1.52 -8.96 1.10 -5.81 5.69 -9.10
Bud Site -1.21 -1.38 -7.97 -7.04 -7.27 -5.72 -8.33 -12.33 -7.68 -2.94 -2.48 -4.60 -11.96 -10.29 -8.44
Cell Periphery 7.36 3.04 -5.66 -7.80 -6.68 1.56 -1.26 -2.35 -9.80 -0.66 6.49 2.15 -4.35 -10.49 -6.79
Cytoplasm 0.78 -3.46 5.20 3.87 7.70 0.36 -6.06 -2.63 -5.03 5.23 0.81 -7.27 -1.64 -2.48 5.43
Cytoplasmic Foci -1.37 26.30 23.70 20.23 -2.93 1.15 10.93 12.81 24.18 5.18 -1.87 26.74 26.74 31.18 -0.31
Eisosomes 5.82 5.77 5.51 -5.24 -4.15 0.64 2.97 2.94 3.43 -0.74 4.53 6.12 6.00 3.12 -3.57
Endoplasmic Reticulum 28.28 6.72 16.25 -9.36 11.04 0.71 2.49 3.40 5.40 1.54 17.32 9.15 17.77 0.31 10.88
Endosome -14.00 8.92 2.70 14.64 -4.47 -4.17 4.54 4.44 11.86 -0.24 -16.89 7.92 2.69 18.24 -4.86
Golgi 12.37 14.67 13.11 0.39 -5.00 -5.75 1.19 -1.19 1.54 -1.74 8.63 13.62 7.01 1.12 -2.78
Lipid Particles 20.51 22.35 -7.43 -13.79 -14.06 0.24 5.47 1.52 2.19 -6.86 9.14 20.62 -2.03 -9.30 -17.42
Mitochondria 6.08 9.48 9.85 3.48 7.82 -7.90 0.79 -1.05 6.43 -1.48 4.16 9.44 8.66 6.87 -1.28
Mitotic Spindle -1.81 -3.58 -3.83 -3.02 -3.29 -2.13 -4.97 -5.78 -4.80 -0.81 -2.74 -5.82 -6.84 -5.63 -3.98
None 9.43 5.83 10.83 2.40 6.95 1.30 3.77 2.77 3.77 -4.15 6.20 7.81 8.76 3.58 1.71
Nuclear Periphery 6.73 -5.10 5.51 -4.04 12.17 0.70 1.69 2.75 3.40 2.05 2.64 -3.42 4.63 2.39 9.90
Nuclear Periphery Foci 6.58 -13.55 -14.40 -15.74 -7.52 6.04 -4.69 -4.79 -17.38 0.60 7.18 -15.77 -19.60 -23.30 -5.36
Nucleolus -2.48 3.32 7.33 6.51 5.00 1.73 3.97 3.87 7.21 -1.46 -2.07 5.61 6.96 9.47 2.75
Nucleus 5.80 -26.80 1.94 -2.73 24.70 4.73 4.81 5.72 2.69 2.01 5.00 -19.72 5.22 0.22 25.22
Peroxisomes 2.05 5.86 5.94 7.65 0.53 -3.93 5.28 5.89 7.01 1.86 1.23 6.07 6.13 9.59 0.48
Vacuole -31.29 -9.06 -23.28 5.55 -20.24 -9.39 -12.66 -22.25 -12.33 -6.87 -30.08 -17.41 -40.07 -4.10 -24.93
Vacuole Periphery -3.17 10.41 10.30 9.26 -0.36 -6.96 2.77 -1.34 1.95 -2.45 -4.58 10.65 1.56 3.99 -2.59
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Heme-binding protein; involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis
Localization
Cell Percentages ER (69%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Dap1

Dap1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dap1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available